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 (DIR) Return to: AVONEX (interferon beta-1a)
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       #Post#: 1772--------------------------------------------------
       Fulminant hepatitis death in patient taking interferon beta-1a
       By: agate Date: August 1, 2017, 12:26 pm
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       The short article doesn't specify whether the patient was on
       Avonex or Rebif. Hepatic function is supposed to be checked
       regularly, or at least that was specified when I was on Avonex.
       From DocGuide Weekly, August 1, 2017:
       [quote]Source: Internal medicine (Tokyo; Japan) 56 (14),
       1897-1901 (2017)
       An Autopsy Case of Fulminant Hepatitis in a Patient with
       Multiple Sclerosis Treated by Interferon-Beta-1a
       Yamazaki Y, Suzuki A, Hirayanagi K, Tsukagoshi Y, Uehara R,
       Horiguchi K, Ohyama T, Tomaru T, Horiguchi N, Nobusawa S, Ikota
       H, Sato K, Kakizaki S, Kusano M, Ikeda Y, Yokoo H, Yamada M
       A 44-year-old woman with multiple sclerosis (MS) receiving
       interferon (IFN)-beta-1a treatment was admitted to a local
       hospital for severe icterus and liver injury. She was
       transferred to our university hospital because fulminant
       hepatitis (FH) was suspected. She was diagnosed with acute-type
       FH based on hepatic coma, severe liver injury and liver failure,
       and she received plasma exchange and continuous
       hemodiafiltration therapy. On hospital day 6, she died from
       liver failure despite intensive care. An autopsy revealed
       histological findings consistent with FH.
       Physicians should monitor the hepatic function of MS patients
       receiving IFN-beta-1a treatment, as serious events can occur in
       rare cases.[/quote]
 (HTM) http://www.docguide.com/autopsy-case-fulminant-hepatitis-patient-multiple-sclerosis-treated-interferon-beta-1a?hash=544098a8&eid=59157&alrhash=2e22ec-4b70c95432d7b63d98dcc4c365f92710
 (HTM) http://www.docguide.com/autopsy-case-fulminant-hepatitis-patient-multiple-sclerosis-treated-interferon-beta-1a?hash=544098a8&eid=59157&alrhash=2e22ec-4b70c95432d7b63d98dcc4c365f92710
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