(DIR) Return Create A Forum - Home --------------------------------------------------------- MS Speaks (HTM) https://msspeaks.createaforum.com --------------------------------------------------------- ***************************************************** (DIR) Return to: LEMTRADA (Campath, alemtuzumab) ***************************************************** #Post#: 2822-------------------------------------------------- (Abst.) ANCA-associated life-threatening systemic vasculitis aft er alemtuzumab treatment for MS By: agate Date: February 23, 2020, 7:20 pm --------------------------------------------------------- From PubMed (February 23, 2020), "ANCA-associated life-threatening systemic vasculitis after alemtuzumab treatment for multiple sclerosis" (HTM) https://www.ncbi.nlm.nih.gov/pubmed/32081100 ANCA vasculitis: [quote][font=Roboto]ANCA vasculitis is an autoimmune disease affecting small blood vessels in the body. It is caused by autoantibodies called ANCAs, or [/font][font=Roboto][/size]A[/font][font=Roboto][/size]nti-[/fon t][font=Roboto][/size]N[/font][font=Roboto][/size]eutrophilic [/font][font=Roboto][/size]C[/font][font=Roboto][/size]ytoplasmi c [/font][font=Roboto][/size]A[/font][font=Roboto][/size]utoantibo dies. ANCAs target and attack a certain kind of white blood cells called neutrophils. They target a part of neutrophils called the cytoplasm (the inside of the cell.)[/font][/quote] [from the UNC Kidney Center Website] *****************************************************