Heart Abnormalities among Covid-19 Vaccinated Children A follow up study (https://bit.ly/3wVSYU8) conducted at the Seattle Children’s Hospital of children suffering myocarditis following their second dose of the Pfizer mRNA vaccine was published in the Journal of Pediatrics on 25 March 2022. The study followed up 16 male children, with an average age of 15 years, 3 to 8 months after their initial diagnosis with myocarditis within a short time frame following mRNA vaccination. The authors used Electrocardiograms and Cardiac Magnetic Resonance (CMR) to examine abnormalities in the heart such as myocardial scarring, fibrosis, strain, and reduced ventricular muscle extension which can be associated with reduced capacity to pump blood and increased risk of heart attack. The authors found that although there was some measure of resolution after 3 – 8 months most subjects still had some persistent abnormalities. Although (initial) symptoms (such as chest pain, and exercise intolerance) were transient and most patients appeared to respond to treatment (solely with NSAIDS such as ibuprofen), we demonstrated persistence of abnormal findings on CMR at (3-8 months) follow up in most patients, albeit with improvement in extent of LGE (a measure of the heart’s capacity to pump efficiently). The authors warned: The presence of LGE is an indicator of cardiac injury and fibrosis and has been strongly associated with worse prognosis in patients with classical acute myocarditis. A meta-analysis including 8 studie found that presence of LGE is a predictor of all cause death, cardiovascular death, cardiac transplant, rehospitalization, recurrent acute myocarditis and requirement for mechanical circulatory support. Full video: https://youtu.be/smKDRiiVIpY