[HN Gopher] Funding for Covid-19 Projects ___________________________________________________________________ Funding for Covid-19 Projects Author : molecule Score : 218 points Date : 2020-03-15 16:35 UTC (6 hours ago) (HTM) web link (blog.samaltman.com) (TXT) w3m dump (blog.samaltman.com) | intended wrote: | Can someone just sell Bidets = better for the environment, and | this ridiculous fighting over TP in the developed world ends. | spookthesunset wrote: | If you look on amazon, lots of them are getting sold out. This | might be what changes people's view on it... | the_af wrote: | I come from a country where bidets are very popular, and I of | course own one: you still need toilet paper. Think when you | wash your hands, how do you dry them? ;) | TeMPOraL wrote: | Fights over TP should disappear soon. It's just a supply shock, | but unlike with PPE, the coronavirus doesn't affect the rate at | which people go through TP, so it should be one time. People | who hoarded will just take more time to buy again. | fortran77 wrote: | An AI system that has been trained on survivability based on | easily cheked comorbidities (age, BMI, smoker) that can instantly | do triage and let hospitals know whether or not to allocate a | hospital bed/ventilator to an incoming patient. | supernintendo wrote: | Please make sure any startup you fund doesn't take a selfish | approach to patents and intellectual property. Any progress on | fighting Covid-19 needs to be shared with the world and not used | as a cynical tool for profit. | vikramkr wrote: | What counts as selfish? If someone is developing a drug for it | but can't make the money back they spent on it because they | don't have patent protection, they're not going to do it in the | first place. A startup will fundamentally need to have | profitability to be worth developing the drug. The government | is a different story, and of course there's a chance the | vaccines come out of the NIH etc. But if it comes out of a | startup in particular, the people behind it we're only driven | to create it for profit (why are they founding a startup | instead of working through academia, or doing it as a | startup/funding a startup instead of as a nonprofit?) And if | that profit motive was required to make this work, then profit | was the tool used to fight Covid, not the other way around, no? | d_burfoot wrote: | Thanks SamA! | fludlight wrote: | You can also try emailing K-12 (6-12 really) schools offering | tech support helping teachers and students set up and use tele- | learning software. | codingdave wrote: | I'd suggest that the K-5 crowd needs more help than 6-12. My | older children already did some of their work online, and when | the schools shut down, the teachers emailed the students to let | them know that they'd be using their existing tools... just | expanding the content. | | But my younger kids have never even used the online tools. They | need more help, and the teachers need more help transitioning | their curriculum to remote classrooms. | tcbawo wrote: | There are a lot of mom and pop stores and restaurants that will | suffer and may go out of business. If there is a secure, | convenient website to set up gift card purchases, it might keep | these places afloat. | wenc wrote: | I was thinking this too, but I'm not convinced the gift card | idea, as it stands, will work for all businesses. There needs | to be some creative thinking to make it truly help small | businesses. | | Gift cards are a deferred liability -- they help cash flow now | but in the future when everybody redeems them, they're going to | eat away at future income, which doesn't leave the mom and pop | store necessarily in a better state. The hope is: (1) a large | percentage of folks never redeem their gift cards; (2) mom-and- | pops can accommodate the increased demand in the future and | still make future income. (3) they can set really limited | expiry dates. But if these assumptions are not true, they will | still have to close. (but yes, let's do gift cards for | businesses where these assumptions are true) | | In some cases, gift cards are not useful especially for non- | scalable businesses like barbershops, which have a finite | number of appointment slots. Gift cards just delay the | inevitable. Barbers can extend hours and open up more slots but | they might never catch up. | | A more appealing idea is a temporary UBI but then we're wading | into political territory. And even with a UBI, it doesn't help | businesses with uncertain demand and perishable inventories. | | I really want to help small businesses: any thoughts from other | folks here? Is there something else we can do? Are there | good/better solutions? | tcbawo wrote: | Maybe something like GoFundMe but with gift cards that have | <100% redemption value, so it's neither entirely charity or | unfunded liability. You need some transparency into the | funding goals. Maybe even provide some sliding scale where | after a certain amount purchased, the gift cards trend | upwards towards 100%. | andrewfromx wrote: | Sam's ending line "And of course, I think the best thing to do is | still to get people to stay home." makes me think we need this | app asap: https://news.ycombinator.com/item?id=22585852 | samirillian wrote: | What about more social network type projects? As someone living | in a relatively cheap apt building in Chicago, I was thinking | that this could be an opportunity to get people to actually | interact more with the aid of technology, form local support | networks for sharing information and other resources, make sure | the most vulnerable people have some support, etc. Lots of people | are stuck at home, lots of people are nervous, lots of people may | need help in the coming weeks. I wish our apartment building had | at least a forum for sharing a little info. | bryanrasmussen wrote: | I guess fixing the problems listed here would be the most useful | to invest in startup wise https://www.wired.com/story/high- | stakes-security-set-ups-mak... as they will be problems that | persist after the pandemic is over, and can secure clients in | wealthy firms for the product that fixes them. | pkaye wrote: | The US ventilator companies say they can already ramp up | production 5x. They just need the orders. And they can probably | make more basic units which might be sufficient | | https://www.forbes.com/sites/baldwin/2020/03/14/ventilator-m... | olalonde wrote: | Why haven't they? There's a worldwide shortage of ventilators | and prices are through the roof. | pkaye wrote: | > The German government just placed an order for 10,000 | mechanical ventilators. What's the U.S. government doing | about a potential shortage here? Not much, it seems. | President Trump alluded to the matter in a press conference | but did not spell out any plans. | | I guess there is not action at the top level. This is a | national emergency and they should be cranking them out like | tanks during a war and distribute to where its most needed. | hanniabu wrote: | > They just need the orders. | jonas21 wrote: | Or rather, one small US ventilator company says they can ramp | up their production by 5x in 3 to 4 months. From your link: | | _"We could increase production five-fold in a 90- to 120-day | period," says Chris Kiple, chief executive of Ventec Life | Systems ... The seven-year-old, 135-employee Ventec is a fairly | small player in a market dominated by Medtronic (under the | Puritan Bennett brand), GE Healthcare and Allied Healthcare in | the U.S._ | | Not to mention that there's a big difference between producing | ventilators at 5x the current rate and having 5x as many total | ventilators available. | brian-armstrong wrote: | Hospitals also need beds and staff to care for patients on | ventilators. They could be well-equipped with the ventilators | themselves and be bottlenecked on people to operate them. | aabajian wrote: | You can use an ECMO instead of ventilation: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185806/ | | Here's a fringe idea in the worse case: Connect one ECMO | oxygenator to multiple patients at once using Type-O negative | blood. You'd have to filter out the O-negative RBC's as they come | in. | hn_throwaway_99 wrote: | This seems pretty insane to me. ECMO in general is _much_ more | dangerous than mechanical ventilation because the risk of | infection and sepsis is so much higher. Certainly understand it | as a last ditch effort, but the resources and risks WRT ECMO is | much higher than mechanical ventilation. | blackRust wrote: | Unfortunately the number of ECMO machines is far cry away from | what is required for this to work: | https://en.wikipedia.org/wiki/Extracorporeal_membrane_oxygen... | | Even if you manage to double or triple capacity unfortunately | it is no match to the exponential growth. | haldujai wrote: | We have a lot more ECMO capacity than people think, CPB | machines from heart surgery cases can be used to provide ECMO | which are at least an order of magnitude more common than | classic ECMO machines. | bryanrasmussen wrote: | I'm somewhat dense - why Type-O? | ipostonthisacc wrote: | it is somewhat universal. type-O blood can be used for all | groups (in general), but type-O patients can only receive own | aabajian wrote: | O-negative means the red blood cells lack the A, B and Rh | antigens on their cell membrane. It is these antigens that | (most) often lead to a host immune response. | Spooky23 wrote: | Type O is the universal donor. | haldujai wrote: | This is an extremely flawed idea. | | Not only does transfusion present a big risk, we quote ~20% | risk of adverse events (minor to severe), but what you're | suggesting massive transfusion protocol (DIC, hemolysis, TRALI, | TACO) AND ECMO which itself is orders of magnitude more | dangerous than ventilation. | | The risks are numerous but for brevity sake you have: Acute | limb ischemia, DIC/other coagulopathies and spontaneous | hemorrhage which carry huge mortality. | | It would be way simpler and safer to connect multiple patients | to the same ventilator who are all on CMV with similar | settings. | | ECMO is not saving many people with severe COVID-19 related | illness. It depends on buying time for your body to recover. | Nearly every case I've read about that required ECMO the | patient died because of multiorgan failure and sepsis. ECMO | only works well in patients with isolated lung (and some | circumstances heart) problems. | danenania wrote: | I wonder how much home pneumonia treatment options like | humidifiers, steam, and drinking tons of fluids can impact the | hospitalization rate? Quitting/taking a break from smoking has to | be a big one too. Can we find ways to encourage more people to do | these things, like some kind of viral science-based "Lower Your | Covid Risk" website or app? It could promote social distancing | too. | | One of the biggest problems so far imo is lack of clear, | unambiguous guidance from authority figures. People in the | general population still have wildly misinformed views. Finding | creative ways to inject this kind of crucial information into the | collective consciousness could have a big impact. | fovc wrote: | There was a comment yesterday about how easy it is to manufacture | iron lungs. A quick search indicates they might be effective | (https://www.ncbi.nlm.nih.gov/pubmed/15065832) | | Is this being explored? | haldujai wrote: | The mechanism of respiratory failure is different in COPD vs | ARDS (in the case of COVID), hypercarbic vs hypoxemic. There is | minimal human research in the use of NPV/iron lungs with ARDS. | As far as I'm aware the technology does not even exist for many | of the ventilation modes we use today with NPV which was | designed for people with polio and paralyzed breathing muscles | rather than "fluid in their lungs" causing the respiratory | failure. | tcbawo wrote: | If cheap improvised medical equipment turns out to be feasible, | I hope government will provide adequate legal cover for those | willing/able to do R&D, manufacture, and distribution. | dnautics wrote: | How about a project to understand who is NOT getting Covid-19? | There are almost certainly healthcare workers in heavily infected | areas who "should have gotten it but haven't". Understanding this | could rapidly lead to: | | - screens to identify who's vulnerable and who's not | | - therapeutic strategies (probably not ready for this round, but | for future rounds) | | edit: removed errant footnote reference | thih9 wrote: | > There are almost certainly healthcare workers in heavily | infected areas who "should have gotten it but haven't"[0] | | It looks like the link is missing. Does anyone have it? | dnautics wrote: | no, sorry, I was going to add more text and put the bullets | into a footnote, but went back to coding. | | If you would like more information on something similar, | consider: | | https://www.theguardian.com/world/2007/may/27/aids.features | | The flip side of this is that I used to work in structural | biology, and there were tons of structural biology grants | flying around justifying studying these antibodies on the | grounds that they might lead directly to vaccination | strategies. Well, that is highly unlikely because some of | these antibodies have a germline (versus adaptive immunity | internal random generator) mutation that fundamentally | changes the higher-order architecture of their antibodies | that makes them not comparable to the antibodies that the | rest of us have. The blatant (deliberate or brainless, I | wasn't sure) mischaracterization by the PIs and the brazen | funding of these proposals (deliberate or brainless, I wasn't | sure) by the grant program managers that contributed me to | leaving academia. I just wish they were honest and said "we | are studying this because it's interesting and we would like | to know more about the universe". | [deleted] | bastawhiz wrote: | I've read multiple reports online that truvada and descocy (HIV | medication sold as a prophylactic, largely to LGBT individuals) | may offer some resistance to COVID-19. I think it's largely | bunk speculation, but research into whether existing, mass- | produced pharmaceuticals would help could be incredibly | valuable. | tjoff wrote: | Don't know about trubada/descocy but they are doing exactly | that. Still, takes many months to get results though. | davmar wrote: | for any of sam's startup ideas to have an impact on the current | Covid-19 pandemic, they need to: | | 0. raise a lot of money because vaccine/therapeutic development | is $$$. it's probably not seed funding. | | 1. be successful in researching and developing an approach that | works with a novel, unproven approach | | 2. get that approach certified | | 3. scale the manufacturing of the novel approach | | 4. deliver the drugs to patients who need it | | 5. do it all in a timeframe that is faster than what existing | companies can do, and within the budget of the money that you've | raised. | | i don't think novel vaccines and therapeutics made by startups | are likely to work in time to have an impact on this coronavirus. | | but, sam's funding can help out if he suggests different | problems: logistics planning, increasing care capacity, and | increased political pressure. | | - in the open letter to mike pence | (https://medium.com/@maxinedexter/open-letter-to-vice-preside...) | they call for call centers to "coordinate transfers of patients | to areas with higher levels or greater capacity for delivering | care." if it doesn't exist, software should power this. | | - same letter: "A tracking method at the state level for people | self quarantined must be instituted for public health | surveillance and follow up." | | - cities need additional mobile quarantine facilities. build them | out of box shipping containers or something. | | for this pandemic, we're already behind the 8 ball so i suggest | picking simpler projects. if you want to fund novel approaches | that require r&d, that's probably more likely to help with the | next pandemic. | taytus wrote: | >You can email me if you want. | | What is Sam's email? | | Thanks! | mceoin wrote: | samaltman@ycombinator.com gives a hit in Superhuman. | ISL wrote: | Finding ways to mitigate the economic impact of Covid-19 is less | sexy, but it is likely to be the place where investors can make | the biggest difference to other humans. | | Zero/low-interest loans will stem the inevitable downward spiral | that comes with loss of free cash flow from otherwise great | businesses. This is the time to ensure the stable capitalization | of good businesses (and investors are likely to get paid back in | spades in karma, if not cash, for doing so). | Theodores wrote: | Well said. | | The lockdown presents an opportunity. Imagine you run a small | customer facing business where the premises could do with | refurbishment. | | Under normal circumstances you cannot close the doors for | however long it takes to redecorate the place, maybe putting in | modern lighting and air conditioning. Too much revenue would be | lost plus there would be the matter of goodwill with customers | discovering rival shops. | | Most of these businesses are cash driven, there isn't a lot in | the bank. So, right now the business has to shut up shop, game | over thanks to consequences of the virus. | | Now, if you did have the capital to spend on the premises, you | could shut the doors to the customers and hire the usual team | to help out on the refurbishment. They might not have the | paperwork for the HVAC work or for doing electrical work but | they could put everything in place for when times change and | the electrician or HVAC engineer could be called out. Painting | the walls or assembling shop fittings can be done by almost | anyone, albeit not as quickly or proficiently as the | professionals. | | When the hysteria is over and 'herd immunity' is reached then | the refurbished business can reopen. With more up to date | premises and a fresh look this should result in better sales. | | Sometimes 'charity starts at home' and helping one's preferred | local business to make something of the opportunity rather than | close is worth a go. If you are a customer then even just | talking to your favourite shop about opportunities is useful, | 'customer feedback'. It could be your hairdresser, a cafe or a | shop that could do with the suggestion. Perhaps they don't | notice the grubby walls as they work there day in and day out, | whereas, you as a customer, might notice such things but never | say anything as you like the staff. Time to speak up before | they close. | voidmain wrote: | Someone should look at Sterilray and Ushio 222nm KrCl excimer | lamps. Light at that frequency is extremely effective at | destroying viruses but probably does not cause much skin cancer | or eye damage like other UV because it is absorbed so fast it | doesn't make it through the dead layer of skin etc. There are at | least some studies but no FDA approval or mass production. If | they work these might make a big difference in transmission in | public spaces, especially via surfaces. | deftnerd wrote: | Even if 222nm has its purposes, the market is crying out for | inexpensive and plentiful UV-C 253nm LED's. | | You can get UV LED's in different wavelengths, but 253nm is the | very effective for disinfection (even though it does suffer | from the other UV damage that you mentioned). It's slightly | wider wavelength might make it more possible to make using | existing LED manufacturing techniques. | | This would open up a lot of possible germicidal sanitation | technologies from integrated germicidal LED's on door handles, | bulbs used with home automation to disinfect a whole home once | everyone has left for the day, to Roomba-like devices that | disinfect floors. | Animats wrote: | On the ventilator front, a good start would be to order one each | of the available ventilators on Alibaba, express shipping. For | all the ones that show up, get them examined and tested and torn | down if necessary. Publish the results. Get emergency FDA | approval. Order in bulk. Make arrangements with the better | suppliers to go to three shifts. Arrange for large air shipments | of the good ones to where they are needed. Find out if there's | something the supplier needs and get it from them. Basically, use | money to overcome all normal obstacles to getting those things | where they are needed. | spodek wrote: | Any tinkerers want to help these low tech versions | https://www.notechmagazine.com/2020/03/open-source-breathing... | | Helping create versions 3d printable or mass manufacturable | could save countless lives. | timcederman wrote: | This is spot on. I emailed officials in my city and county with | this suggestion earlier this weekend and received some mild | interest. From my research into the situation they do have | stock and the current bottleneck is shipping, but stock is | making it over in 2-3 weeks. | ma2rten wrote: | I doubt that there are going to be a bunch of ventilators that | you can just order on Alibaba. | jacquesm wrote: | Take your pick: | | https://www.alibaba.com/showroom/emergency-ventilator.html | BurningFrog wrote: | You can order. But will they arrive? | jacquesm wrote: | That is a good question. I suppose there _was_ some stock | of these before the crisis but those are very likely all | depleted. Still, with this many suppliers it might not | hurt to ask. Dutch proverb: "If you don't shoot you will | certainly miss". | microcolonel wrote: | For what it's worth, China has literally turned around | pending export medical supplies, and banned certain | exports. Ventilators seem like they would be on that | list, if it has not been withdrawn yet. | thaumasiotes wrote: | > Dutch proverb: "If you don't shoot you will certainly | miss". | | Huh. The idea is certainly around in the US, but I'm kind | of surprised I can't think of a matching proverb. | | We have a very close match, but it's considered a witty | quote from a particular person (no consensus on who) -- | "you miss 100% of the shots you don't take". | | There's also something along the lines of "you can't get | what you don't ask for". There's also an individually | attributed version of this: "if you don't ask, you don't | get". I had to look this up. There is no really common | version. | | And of course, there's "ninety percent of success is | showing up". Again this is attributed -- quote trackers | seem to agree that it should be "80%", not "90%". But | this one is common enough that I could see it becoming a | proverb eventually. On the other hand, this has gone | somewhat afield from "if you don't shoot, you won't hit". | stormtroper1721 wrote: | "You miss 100% of the shots that you don't take" is one | ma2rten wrote: | Fair enough, but I checked the first one. They were already | certified by western agencies. | genbit wrote: | Here you go, startup idea: emergency logistics. Company that | can quickly ship and verify good quality approved medical | equipment and supplies to the epidemic area. | jacquesm wrote: | That's called the Red Cross. | mceoin wrote: | Mycology. Not a company but a novel and underinvested space with | 3000+ yr history with antiviral applications. Paul Stamets is the | go-to guy here but likely slammed. His talk, into the mycoverse, | goes into detail about how he was brought in to do battery | testing post-9/11 and how basically all polypore mushrooms | (common globally) have some antiviral properties. Some are super- | potent. At risk of being called "the crazy mushroom guy" I'm | including here because I know this is a vastly underinvested in | space and has huge latent potential WRT antivirals. The reason it | is underinvested in is because patents are hard (used for 1000s | of years) so big pharma stay away. Long shot, but also could be | tested everywhere, reasonably cheaply. | https://www.youtube.com/watch?v=f0rkcrWqsV4 | Alex3917 wrote: | Are there any mushrooms that have shown antiviral effects | against SARS or other viruses in the Coronavirus family? | | I know there are a ton of studies on this for plant-based | medicine in relation to SARS and MERS, but I haven't looked | much into mushrooms for this. (Even as an amateur mycologist.) | | I know folks have been recommending cordyceps for COVID-19, but | not because it has antiviral properties. Given that hunting for | cordyceps is about the only safe thing to do in NYC right now, | maybe this will be the year I actually find it for myself. | (Albeit the species that's common in NYC doesn't have any | history of being used medicinally afaik.) | mceoin wrote: | I haven't seen anything specifically related to COVID-19 and | won't speculate. I'm also not a scientist or medical | professional, so just think of me as some guy on the Internet | saying "mycology is an interesting non-big-pharma industry | that has bio-prospecting potential due to its anti-viral | properties", and Paul Stamets is the source of that | statement. | | (Personally, I'm making a lot of Reishi tea and taking a | spectrum of polypore supplements as a general immune booster, | not a specific defense against COVID-19). | | P.S. good luck finding cordyceps! | andreyk wrote: | "I'm trying to fund startups/projects helping with COVID-19, | because it's basically the one thing I know how to do that can | help. " | | You can... donate to the many existing efforts already fighting | this? | natalyarostova wrote: | Sam's expertise isn't just about money. It's about identifying | the good ideas in the sea of ideas, and helping them get | connected. | hanniabu wrote: | It doesn't look like the items identified in his list are | things that can really help now though. They seem like | they're things that will only be useful in future pandemics. | zmj wrote: | Like the second wave of COVID-19 next winter? | DoreenMichele wrote: | I'm going to note two things here: | | First, Sam Altman is no longer president of YC and this is his | personal blog. So I think it is probably a mistake to conflate | his writing with YC policy. | | Second, I've been posting here more than a decade. I was | initially very open about my diagnosis and my pursuit of non-drug | solutions, but that went weird and problematic places, in part | because people on the leader made problematic comments at times | that looked to me like the baked in assumption was "She's just a | girl. She couldn't possibly come up with a brilliant idea like Do | A Website about her health stuff." The website in question was | listed in my profile at the time. He hadn't taken thirty seconds | to look at my profile before opening mouth and inserting foot. | | Sadly the person may have been trying to flirt with me. It's a | debacle I feel my reputation has never recovered from. | | I still don't know how to get taken seriously and I absolutely | can't single-handedly dream up a fix here. | | I can't figure out what to talk about without engagement. I can't | self promote when various gatekeepers actively exclude me for not | having the right kind of mostly male-coded credentials because I | was a homemaker and full-time mom for a lot of years. | | I've spent nearly 19 years getting better while the world calls | me crazy and actively denies me support. The odds are extremely | poor that I will ever get taken seriously. | | But if it genuinely bothers you that people are dying from this | infection, maybe stop and consider setting aside your sexist, | classist prejudices about me and try to find some way to help me | find my voice and share what I know that has allowed me to | successfully get off all the drugs and generally grow healthier | while the world laughs in face and tells me I'm a liar and | nutcase. | | And if insisting I'm a lunatic who deserves zero respect matters | to you more, then you don't really want a solution to this | problem more than you want to remain married to unpleasant | character traits. | | Because you have this person in your midst whose very life | depends upon such expertise and would love to share useful | information and that's not a secret. It's just absolutely not | taken at all seriously and I'm routinely attacked for trying to | talk about health stuff at all, even when I'm doing so for my own | edification with zero intent to convince anyone else of anything | at all. | taytus wrote: | I read your post 4 times. I still have no clue what you are | talking about. | adamsea wrote: | Wouldn't it make more sense, from a public health perspective, to | put that money into the existing local institutions (hospitals, | health clinics, food banks) which are vital and soon may be | strained to the breaking point? | CPLX wrote: | The thing Sam Altman could have done, and still could do, that | would have by far the most impact in this and similar crises, is | support the adoption of universal health coverage and sick leave | policies, as well as financial assistance for those devastated by | these shutdowns. | | Startups are cool. But to the extent the Silicon Valley community | has fought against a social safety net and effective public | sector they're part of the problem. | | Not singling him out specifically here as my understanding is | that he actually has done some political work along those lines, | but the first sentence here implies that investing in startups is | the only thing he knows how to do. That rings false. | | He's very wealthy and powerful. He has enormous influence over | people who set employee policies at important companies and has | the ear of world leaders.[0] | | There's many things he could do that are much more effective than | investing in startups. | | [0] https://youtu.be/rKoACC5iOhQ | pmorici wrote: | This seems obviously false. Italy has universal health coverage | and they have one of the worst outbreaks and worse fatality | rates of any country. This doesn't feel like the right time to | promote preferred political agendas. Doesn't matter who pays | for it when there is no vaccine and no cure. | melenaboija wrote: | Partially agree with you. | | Universal health coverage in this situation is meant to treat | everybody in equality for same problem and I would say it | doesn't matter who pays for it as long as everybody will get | treated in a similar way. | | Agree on European governments did not the right thing, but | again, not sure if that has something to do with universal | health. | nrp wrote: | On universal paid sick leave, the intent is to enable people | to not go into their workplace when they could be contagious. | The choice between risking getting others sick or going broke | and getting evicted isn't one people should be forced to | make. | | On universal health coverage, the major difference is what | the recovery looks like (potentially after the vaccine in | countries where it's too late for containment). If there's | any silver lining to this pandemic, hopefully it's that | politicians who oppose universal health coverage become | unelectable. | pmorici wrote: | I understand that but the op is advocating that those | things would do more than having an ample supply of PPE and | an effective treatment and vaccine which is total nonsense. | js2 wrote: | We'll soon see how America's broken healthcare system | combines with its undocumented immigrants and homeless. | Alex3917 wrote: | And also people of color not filling out the census because | they're afraid the government is going to send people to | lynch them. Healthcare resources are completely | misallocated because people are scared to tell the | government where they live. During the last census, the | response rate in Harlem was something like only 65%, which | the government can tell based on electricity usage and | toilet flush data. | adrr wrote: | Sick leave is in the house bill that passed yesterday along | with paid family leave. White house supports it so it should | pass the senate with little problems. | CPLX wrote: | No it isn't. It excludes almost everyone. | | That bill is an embarrassment. Doing something about _that_ | is kind of exactly what I'm talking about. | [deleted] | gji wrote: | Those benefits only apply to people who work at companies | that have less than 500 employees. Unfortunately, that leaves | most people in the lurch. | | https://www.nytimes.com/2020/03/14/opinion/coronavirus- | pelos... | cheez wrote: | Those are the companies that won't survive without it. The | bigger companies are expected to fund it themselves. | throwaway8291 wrote: | How true. I believe the US will see an even worse fallout than | Italy - because people who can afford private medical personal | tend to question whether healthcare is a business model at all | ("Is curing patients a sustainable business model?", GS). | | America has the most uplifting and free-spirited legacy, but it | has been transformed in the past decades into the most | primitive form of greed and selfishness possible. Covid-19 is | only the eye-opener. | | FTR: I believe the US will lose 5% of its population to the | coronavirus in 2020. Not being panicky, just multiplying. | ma2rten wrote: | Coronavirus has death rate of 1-2%. It might be slightly | higher if the health care system gets overwhelmed, but the US | has a head start on Italy/China in terms of social distancing | measures. | varjag wrote: | 3.4% | ma2rten wrote: | That number is a crude estimate based on reported cases. | The real number of cases is obviously higher than the | ones being reported. | varjag wrote: | These are WHO figures. You are speculating. | ISL wrote: | What odds are you giving for the 5% prediction? | | COVID-19 is going to hit us hard, but I believe deeply in | America's ability to adapt and pull together. We are | fractured and almost-leaderless today, but the United States | tends to do very well against a common challenge, once the | scale of the challenge is understood. | [deleted] | aaronbrethorst wrote: | The United States's greatest challenges of the 20th century | were only dealt with _after_ the country had strong | leadership at the top. There is zero chance the U.S. will | get that aforementioned strong leadership before January | 2021 at the earliest. | darawk wrote: | I will make a bet with you for whatever amount of money that | you want that every single prediction you just made is false. | On a per capita basis, the US will have a better time than | Italy. The US will lose _nowhere near_ 5% of its population. | Not even 1%. | | Happy to formalize it and bet for real, if you'd like. | CyanLite2 wrote: | 5%? That's like 15-20 million people. Doubt it. We, the | United States, have a lot of problems. We're greedy. We're | arrogant. While we can't prevent all deaths, we're not going | to let 15-20 million people die to a virus in this modern age | of technology and healthcare. | throwaway8291 wrote: | I hope for the best. | onetimemanytime wrote: | >> _we 're not going to let 15-20 million people die to a | virus in this modern age of technology and healthcare._ | | well, you have to take measures weeks and months ahead, or | else it doesn't matter...lungs need oxygen. | heretoo wrote: | Technology doesn't help once the number of cases needing | intensive care exceed the capacity. Healthcare doesn't | exist without technology. | | Italy exceeded that limit in the last two days, so now they | have to decide who has the highest chance of survival, and | those people get intensive care, if it is available. | i_am_proteus wrote: | Neither agreeing nor disagreeing with your point, but | deliberating over what could have been done in the past does | not help solve a crisis in the present. | hn_throwaway_99 wrote: | I very much disagree. The mistakes that were previously made | (both broadly socially and specific instances, such as | closing the pandemic response team and the delay in testing) | were all incredibly foreseeable. I find it the height of | dishonesty to say "Gosh, we had no idea what would have | happened, we just have to focus on the present". Now, I don't | think you're saying that, and you're right that the current | situation is where we are and we should focus on what we can | actually do. In the "never let a good crisis go to waste" | vein, though, one thing we can actually do is make people | realize that the health and well-being of your neighbors is | inextricably linked to your own. | CPLX wrote: | I mean today, literally, he could call Nancy Pelosi, who most | certainly knows who he is and would call him back, and scream | at her for the insane lack of direct federal action to help | regular workers affected financially by this crisis in the | bill they just passed. | | If enough _people like him_ did that to our world leaders you | can be damm sure it would make a difference. | whiddershins wrote: | Who isn't affected? Are you arguing we should | simultaneously bail out the whole country? | CPLX wrote: | Yes of course. The government should take steps to | stabilize the whole country and reduce the damage caused | by mass disaster events. That's what governments are for. | whiddershins wrote: | I don't disagree, but I find your general stance of "of | course my ideology is reality" totally problematic. | | Edit: To clarify there is a wide array of opinions about | "what government are for" and "what governments should | do" ... I think it is important to acknowledge that when | expressing an opinion about what you think. | kick wrote: | I think implying that he doesn't support those isn't | necessarily in line with his previous statements. | | He's previously made statements in favor of _at least_ | universal healthcare, and it seems incredibly unlikely that he | doesn 't support sick leave policies. | claudeganon wrote: | Ycombinator funds several startups whose success depends on | Medicare for All not happening. | kick wrote: | They've also funded startups in bids to try and make | universal healthcare happen: | | https://blog.ycombinator.com/yc-research-universal- | healthcar... | | Also, you shouldn't refer to universal healthcare/single- | payer as a concept with "Medicare for All." Medicare for | All is a compromised American policy proposal inferior to | what most countries have had for years. | claudeganon wrote: | Medicare for All is the only meaningful proposal with | mass support inside the Overton Window of American | politics right now. I'd prefer a robust national | healthcare service, but that's not on the table. | | Watsi is more akin to GoFundMe for care in the developing | world, which, while admirable, has little to do with | creating a universal healthcare system anywhere. | dang wrote: | Please don't take HN threads on generic tangents. They're | predictable. | | https://hn.algolia.com/?dateRange=all&page=0&prefix=false&qu... | throwGuardian wrote: | Italy has both universal health coverage and sick leave | policies, but is still reeling with a 7% mortality rate [1] and | crisis. Neither replaces good leadership and policy/decision | making by public health officials, and certainly has ZERO | effect on pandemics. | | FYI, countries routinely provide free health care [2] during | pandemics because it typically is an existential crisis for | it's civil society and economy. | | [1]: https://www.ccn.com/coronavirus-death-rate-soars-to-7-in- | ita... | | [2] : announcement about US COVID-19 testing and treatment: | | For USA - | | Where to get COVID-19 test? | | Enter your zip code to find out the nearest COVID-19 test site. | (from US HRSA.gov website) https://findahealthcenter.hrsa.gov/ | | 1. Go to clinics instead of crowded large facilities. | | 2. Fees: Testing and Treatments are free. | | If confirmed, home isolation for 14 days, please help stop | spreading COVID-19. Proactive screening to stop the spreads. | randomsearch wrote: | > 7% mortality rate | | Please don't use such misleading figures. Spreading fear is | dangerous. This number is known as a "naive case fatality | rate", with the emphasis on naive. And you're even quoting | just for one country - cherry-picking. | | The UK CMO has said the mortality rate for COVID-19 is likely | 1% or less. | | Please, act responsibly. The situation is serious and | difficult enough. | throwGuardian wrote: | The only person taking anything I said out of context is | you. I've been very specific about the 7% estimate being | unique to Italy, replete with a source. I've never claimed | that to be the overall wordlwide mortality rate, so read | before accusing someone. | | > Please, act responsibly .. | | I suggest you practice what you preach, and read someone | else's well intentioned, informed opinion without | attributing malice or intent to spread falsehoods. | | Most of all, the false narrative that a universal health | care system somehow handles pandemics any better is clearly | being proven wrong in the case of Italy, which is what I | was trying to point out | danenania wrote: | No one really knows how the number will turn out. There are | factors that could push it down: lack of testing, lots of | mild cases; and factors that could push it up: the disease | takes a long time to either recover or succumb to, so many | of those who will end up dying from it haven't died yet. | | Resiliency of healthcare systems also clearly has a _major_ | impact. It might be well under 1% in a "first world" | country where hospitals can keep up, and well over 10% in a | "third world" country where they can't. | | While a 7% mortality rate certainly isn't some kind of | objective fact, it's unfortunately not out of the realm of | possibility for us in a worst-case scenario where the | healthcare system is completely inundated. It's better to | face up to that possibility than downplay it even if it | scares people, because we urgently need people to act so it | doesn't get that bad. While I agree that people shouldn't | fear-monger, it's far more irresponsible at this point to | downplay the risk than to (arguably) overstate it. | whiddershins wrote: | This is a negative and overall unhelpful comment. | | Not only do I not agree with your characterization of what is | useful for him to do, your ideas about health care policies and | mandatory sick are irrelevant, distracting, unimaginative, and | an example of moral posturing that takes the form of demanding | employers somehow take this burden, basically it is moral for | you to demand someone-not-you foot the bill for something you | think should happen. | | I deeply wish this wasn't the highest voted comment on this | submission. | saiya-jin wrote: | Well here is where you disagree with most of the HN crowd | including me. Maybe you are rich enough or insensitive enough | to not care. That in fact doesn't matter at all. | | Free/almost free good enough healthcare, and education in | similar vein are cornerstones of any society that would like | to call itself fair, just and overall good place to live, not | only for few elites. Everybody benefits from it, whole effin' | mankind benefits from it long term. | | Heck, even though I am relatively young and properly healthy, | so I don't need to spend a cent on healthcare, I am happy to | pay (swiss) one so that other benefit. Fuck society that | doesn't do that. | whiddershins wrote: | These things aren't free. It is merely shifting the costs. | | Shifting costs to employers (mandatory paid sick leave) is | generally immoral. | | If people want to provide a benefit, do it with government | spending, and remind yourself it is your money (taxes) that | funds it. | | If you are still willing to do it, at least you are putting | your money where your mouth is. | whiddershins wrote: | Also "Fuck Society that doesn't do that" [you are Swiss?] | Am I understanding you correctly? | | That's grossly insulting and jingoistic. Maybe you should | rethink your nationalism and arrogance. | ma2rten wrote: | Health insurance companies have already said they will cover | COVID without copay/deductibles. I am sure that there will be | free/low cost options for people without any insurance. | | The people who profit from the current system know that there | is a presidential election in November. They can't afford to | let public opinion go against them. Ironically, I think that | this event will cement the current system more. | claudeganon wrote: | > Health insurance companies have already said they will | cover COVID without copay/deductibles. | | This has been said about testing and coverage for testing is | included in the bill that passed the house. But I've seen it | nowhere reported that this is true for treatment. What's the | source for this claim? | | > I am sure that there will be free/low cost options for | people without any insurance. | | The only provision currently on the table is Medicaid | expansion to states for treatment, but the amount of people | who are or will be ineligible for Medicaid (assuming they got | laid off) is quite large. I'm not certain how you can be | "sure" of this. | ma2rten wrote: | It turned out it was a misstatement by Trump: | | https://www.cnn.com/2020/03/12/politics/fact-check-copays- | co... | amluto wrote: | Which means that, once a treatment or vaccine is available, | the vendor can charge essentially whatever they please. | | I think the federal government should buy or acquire by fiat | the rights to produce remdesivir and contract, immediately, | with multiple vendors to start mass production. If the trial | pan out, the US alone may need enough to treat a few million | people. If the trials don't pan out, some money is lost. | | (I'm not saying Gilead shouldn't be fairly compensated. By | all means, pay them a few billion dollars. But don't allow | them to extract $50k per case. And don't allow them to delay | widespread availability while negotiating.) | | FWIW, China appears to be doing this right now. A Chinese | company is manufacturing the drug now and is essentially | ignoring the patent. | rjzzleep wrote: | Let's not forget that the US did that with the Anthrax | vaccination. | | https://www.theguardian.com/business/2001/oct/23/anthrax.bu | s... | fma wrote: | If I recall, in addition to ignoring the patent, the | Chinese company is taking the Gilead drug, repurposing it | and then owning a new patent for the Corona virus... | amluto wrote: | To some extent the legal wrangling its irrelevant. China | is likely to want large amounts of the drug, and they | aren't waiting. Presumably there will be a lawsuit and a | settlement. Gilead has very little leverage in China, | unless they are able to outproduce the home grown | manufacturer. | felltrifortence wrote: | We are launching a initiative to showcase tech projects to fight | the covid-19 virus. Fell free to submit your projects | https://taikai.network/taikai/challenges/covid-19 | andrewdubinsky wrote: | Quarantine Enforcement using GPS with Symptom Tracking | https://www.proveneapp.com | | Video: https://vimeo.com/395294573 Deck: | https://www.dropbox.com/s/128ef7cmu62yv9i/Provene%20Quaranti... | | It's a monitoring platform - Used for jail diversion, recidivism, | drug treatment, etc...Lots of great use cases around quarantine | and tracking. | [deleted] | nenadst wrote: | just heard this on https://peterattiamd.com/peterhotez/ | | apparently Dr.Hotez has a Sars-1 candidate vaccine antigen which | could be repurposed for Covid-19, | | https://grantome.com/grant/NIH/R01-AI098775-03S1 | | but they don't have funding to move it to clinical trials .. | [deleted] | leakybit wrote: | There already exists a low cost ventilator that was designed for | the India market. | | https://www.agvahealthcare.com/ | | but good luck getting fda approval. | jacquesm wrote: | If the choice is no FDA approved ventilator vs one that is not | approved I think the second option is the better one. | Emergencies will change the landscape rapidly to the point | where such luxuries as FDA approval will no longer matter as | much as they did before. | quaquaqua1 wrote: | The ventilator most likely is not approved for | political/cronyism reasons, rather than safe functionality | avip wrote: | FDA has emergency approval process and it'll be used when | shit hits the vent. | | In fact it was just used like two days ago. | deepnotderp wrote: | I wonder if we can just use a $250 Jackson-Rees circuit and an | electric motor as a DIY ventilator in a pinch. | _hardwaregeek wrote: | This does seem to be a worthwhile effort and I have no doubt some | good will come of it. But I'm not sure targeting COVID is the | best idea. Projects can certainly help with that, but they need | to scale, fast. Plus any sort of physical requirements like | manufacturing is out of the question. What I'd be worried about | is the _next_ COVID. I don 't mean this in a literal, disease | based fashion. We should be asking about the next global | disaster. How can our infrastructure break down? What can we do | to strengthen it? Who is vulnerable? | | Also I'm a little concerned about medical projects that are | created in an emergency and attempting to do fast track research. | Immediate solutions may sound great but we don't want to do more | damage in our hastiness. Urgency can lead to wishful thinking | which can lead to disaster. | [deleted] ___________________________________________________________________ (page generated 2020-03-15 23:00 UTC)