[HN Gopher] Can you kill coronavirus with UV light? ___________________________________________________________________ Can you kill coronavirus with UV light? Author : tartoran Score : 82 points Date : 2020-03-28 19:44 UTC (3 hours ago) (HTM) web link (www.bbc.com) (TXT) w3m dump (www.bbc.com) | augustt wrote: | Does anyone know how LED-based UVC lamps like [1] with >300 LEDs | can sell on Amazon for less than $100 when it appears the | individual LEDs are fairly expensive? On DigiKey/Mouser the | cheapest price I can find is still more than $1/LED [2]. | | [1] https://www.amazon.com/2020-Newest-Germicidal-Lamp- | Light/dp/... | | [2] https://www.mouser.com/Optoelectronics/LED-Lighting/LED- | Emit... | nimbius wrote: | hey! relevant anecdotal data here. I work in an automotive repair | garage. Anyone who has to drive a vehicle dropped off by a | customer has to make sure its been UV sanitized first. We drape a | 40 watt CFL UV lamp from your rearview mirror, put your floor | mats on your windshield and rear window, and cover the windows | with scratch mats for 35 minutes. After the timer goes off, a big | blue sticker goes on your window. We then do it all over again | before we give the truck or car back to you. | | We had 2 ozone generators we were using (normally to remove | cigarette smoke from car seats) but they take hours. the bulbs | are cheaper and faster!! | makomk wrote: | Big Clive over on YouTube was complaining the other day that | certain sellers of these lights had taken part of his video | warning against exposing skin to them and used it to claim they | were skin-safe when promoting them for use against the | coronavirus. It was some way into a multi-hour livestream, so I'm | not going to try and dig it out though. | herf wrote: | For anyone who's interested, CIE recently made their UVGI | standards available for free ($150 normally): | | http://files.cie.co.at/cie187-2010%20(free%20copy%20March%20... | http://files.cie.co.at/cie155-2003%20(free%20copy%20March%20... | | Generally you don't want to be around most UVC (253nm) because | these wavelengths are very good at giving you cataracts, etc. So | if you buy these things online, don't stay in the room when you | turn them on. | | There are some newer lamps (210-220nm) that don't seem to | penetrate the outer layer of the epidermis (cornea or skin) and | so might be OK for occupied spaces. But companies are still being | very cautious about occupied uses, because this all still has yet | to be proven in real life. Also, 220nm requires excimer lamps, so | 253nm is way easier to get for now. | prox wrote: | How about just heating your mail in a dry oven? Thats what | Stanford tested for PPE masks. | | Or just waiting 24 hours or more works as well, | wideasleep1 wrote: | Just to add, when I did some research on excimer lamps last | week, producers are few, and the research I discovered were | sometimes using the 253nm lamps, but adding filters to get to | the 210-220nm range. It quite confusing, to say the least. | | Edit: Indeed the article linked above is one such study:"We | used a bank of three excimer lamps containing a Kr-Cl gas | mixture that predominantly emits at 222 nm25,26. The exit | window of each lamp was covered with a custom bandpass filter | designed to remove all but the dominant emission wavelength as | previously described15. Each bandpass filter (Omega Optical, | Brattleboro, VT) had a center wavelength of 222 nm and a full | width at half maximum (FWHM) of 25 nm and enables >20% | transmission at 222 nm." | sakoht wrote: | It's sad that even the BBC allows people who don't know what they | are talking about to spread propaganda, not even knowing it. It | kills everything the size of a virus because of its size, not | some magical attributes the virus may or may not have. The other | comments show three recent scientific publications in top-tier | journals showing the narrow wavelength (222nm) that doesn't harm | human skin or eyes. | whatshisface wrote: | > _It kills everything the size of a virus because of its size, | not some magical attributes the virus may or may not have._ | | It wouldn't cause a tiny iron sphere to disintegrate. It's not | true that everything the size of a coronavirus can be "messed | up" by UV light. | Confiks wrote: | Has anyone found anything on the health implications of mounting | 220nm lamps [1] indoors, _beyond_ the issue of damaging human | DNA? In other words, if you assume those lamps to be safe to | living cells due to the light not penetrating beyond the first | layer of dead skin cells, what other problems might there be? | | Our skin surface contains a lot of living bacteria. Different | strains seem compete with each other, and for example an | overgrowth of staphylococcus aureus seems to be correlated with | skin issues. In that sense living bacteria protect our skin. How | would an far-UVC 'antibiotic' lamp influence bacterial | repopulation later? Either on skin and in spaces. Would it impair | immune system development? | | Viruses seem far more fragile than bacteria, so perhaps a low- | power far UVC-lamp will be enough to kill viruses but leave the | bacterial populations on skin and objects intact | | [1] https://www.nature.com/articles/s41598-018-21058-w | fabian2k wrote: | You get a nasty sunburn from resonably strong UV lamps. I've | seen that happen with people being very careless in the lab | when using a UV bed for gel electrophoresis. | | These are UV lamps strong enough to visualize ethidium bromide, | I'm not even sure if they're strong enough to kill bacteria | quickly, though I'd guess they might be. UV lamps are really | not something you should point at humans. | RL_Quine wrote: | It also burns your retinas and produces ozone. | CamperBob2 wrote: | No optical damage in this wavelength range (although the | ozone may still be an issue.) | | Suggest reading the articles people have linked to in this | thread, pretty interesting stuff. I had no idea that there | was a portion of the UVC spectrum that doesn't have | significant harmful effects on humans. | daenz wrote: | >In short: no. | | https://en.wikipedia.org/wiki/Betteridge%27s_law_of_headline... | [deleted] | dougmwne wrote: | Please do not spread disinformation. Your statement contradicts | the article. This is a time when we need to be very careful | about what we are sharing on social media. The article explains | that artificially produced UVC is effective against other | chronaviruses, but that studies on COVID-19 specifically and | sunlight generally are lacking. | vultour wrote: | That is literally a quote from the article. | NullPrefix wrote: | >Your statement contradicts the article | | The article itself contradicts the article | [deleted] | m-p-3 wrote: | But UVC has been shown to be effective against SARS[1], so | there is a good chance COVID-19 would also be affected. | | [1]: | https://www.sciencedirect.com/science/article/pii/S016609340... | | > The virus was inactivated by ultraviolet light (UV) at 254 nm | | > At 3 cm our UVC light source (254 nm) emitted 4016 mW/cm2 | (where mW = 10-6 J/s) and the UVA light source (365 nm) emitted | 2133 mW/cm2, as measured by radiometric analysis (Spectronics | Corporation). After exposure to the UV light source, virus was | frozen for later analysis by TCID50 assay using CPE as the | endpoint. | | > Exposure of virus to UVC light resulted in partial | inactivation at 1 min with increasing efficiency up to 6 min | (Fig. 1A), resulting in a 400-fold decrease in infectious | virus. No additional inactivation was observed from 6 to 10 | min. After 15 min the virus was completely inactivated to the | limit of detection of the assay, which is <=1.0 TCID50 (log10) | per ml. In contrast, UVA exposure demonstrated no significant | effects on virus inactivation over a 15 min period. Our data | show that UVC light inactivated the SARS virus at a distance of | 3 cm for 15 min. | | So UVC would be indeed effective by these metrics. | | I kinda hope we can build something similar to disinfect | laptops and cellphones at work, there are so many people | touching those and taking the habit of flooding them with UVC | before working on them or giving them back to a user would be a | good step to reduce transmission. | IgorPartola wrote: | Just an anecdote but in college I had a chemistry professor | who had the absolute filthiest keyboard I have ever seen. It | was famous throughout the university because it easily had | 1.5mm of grime on every single key. I asked him about it once | (I assume others did too) and he said that every year the | first year biology students swab his keyboard to grow | bacteria in Petri dishes as a part of their curriculum. While | those Petri dishes with swabs from other place grow like | crazy, nothing ever grows from his keyboard. | smileysteve wrote: | This is a pretty sham conclusion. "No" if you use where people | are. No mention of the utility in cleaning areas that are | temporarily closed to the public. | | Light hits a lot more surface than just you are spraying and | wiping. | | In things like grocery stores being cleaned every night; or even | with modern proximity sensors being able to turn on a 5 min burst | of uv-c without anybody in the room. Uv-c (while yes requiring | precautions) should work great. | | I happened to have bought a uvc wand in November. It has a button | and tilt sensor so it's hard to accidentally scan over your eyes. | It's definitely reassuring to "wipe" the phone and door handles | when I come back in the house at close proximity for a few | seconds. | perl4ever wrote: | I'm not running out to get any sort of UV lamp now but I am | mildly interested in a thing I heard about that works with forced | air ducting in a home AC/heating system. Not sure if it would | help with allergies. | LifeLiverTransp wrote: | You can even disinfect breathing air, if you have a reflective | pipe that is long enough.. and a uv source. | tiku wrote: | Time for led bulbs that also contain uvc light, perhaps with a | battery so that you can clean a room after you turn of the light. | blackhaz wrote: | I have ordered a 15 W Chinese E27 UVC (200-275 nm) lamp from | Amazon, and a E27 to wall socket plug with remote control. I am | going to place it in the quarantine zone downstairs to zap | incoming mail and packages, just for any case. | | In one SARS-CoV study [1] the authors have irradiated SARS-CoV | with a 254 and 365 nm UVC-UVA light source that emitted 4016 | mW/cm^2. They found that "exposure of virus to UVC light resulted | in partial inactivation at 1 min with increasing efficiency up to | 6 min (Fig. 1A), resulting in a 400-fold decrease in infectious | virus." | | If my math is correct, a 15 Watt UVC light bulb will provide 4.77 | W/m^2 flux within the radius of 0.5 m - assuming it emits | omnidirectionally. Assuming the delivered power versus | inactivation efficiency relationship is linear, it would require | roughly about an hour of zapping to achieve the same levels of | inactivation with a 15 W lamp. | | Yes, we don't know if SARS-CoV inactivation times are comparable | to that of COVID-19, but it's better than nothing. I am not a | biologist, and micrographs of both viruses look somewhat similar. | I wonder if they are structurally similar, should we expect | similar susceptibility to incoming UV photons? | | [1] https://medtradex.com/assets/Uploads/Literature-UVD- | Corona.p... | lvturner wrote: | Would you mind linking to the light you bought? Or a comparable | one l. | blackhaz wrote: | Here is the one. I don't know if it performs in spec. Never | bought one before. | | https://www.amazon.co.uk/gp/product/B085HZK755/ref=ppx_yo_dt. | .. | jennyyang wrote: | I bought a cheap glass aquarium for my UVC light bulb. | Glass block UVC light completely so it becomes safe to use | that for smaller items. Also you will produce a lot of | ozone, so do this outdoors with a lot of ventilation. | walterbell wrote: | Because this is (a) NOT Far-UVC, and (b) 360-degree light | that shines in all directions, the only way to use it | safely is with a remote power switch or a short timer so | you (and pets) can get out of the room before the light | turns on. Don't re-enter the room until the light is | switched off remotely or with a timer. It is hazardous to | your eyes and skin. | | Could it be used in a spotlight lamp that directs all the | light in one direction? | jennyyang wrote: | I mention below I place the light bulb (using a hand-held | socket) in a glass aquarium. Glass completely blocks UV-C | light. The other hazard is ozone, so I use this outdoors | on my patio or garage. | nerfhammer wrote: | > Glass completely blocks UV-C light. | | Erm, then why do they come in glass tubes like florescent | lights? | blackhaz wrote: | Yeah, I got a E27 socket wall plug with wireless control. | I assume it should be possible to get a remotely | controlled lamp with reflector to make a spotlight out of | it. | bikenaga wrote: | This is a 3-watt handheld - the power may be too low. | | https://www.amazon.com/Foldable-Travel-Household-Wardrobe- | To... | jennyyang wrote: | One thing to note is that in your calculations, you are using | 50cm distance, but in the study you linked, they are using 3 cm | distance. Since this is inverse square law, that makes sense it | would take longer to deactivate. | | For another point of reference, this study[1] says it takes 1.8 | J/cm^2 to deactivate the flu virus. I'm not sure which is more | hearty but from my calculations, it seems as though it's | similar (about 2 J/cm^2). If that's the case then if you | brought the intensity of your light up (bring the bulb much | closer and possibly wrap it in material that reflects UV-C if | that's even possible) then it would only take seconds to | deactivate the virus. | | [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699414/ | blackhaz wrote: | As far as I understand, we are talking about flux - per area | at specified distance, not luminosity. I did recalculate flux | for 0.5 m. | jennyyang wrote: | No. The study I referenced used total energy per cm^2 | required to deactivate the flu virus, which is J/cm^2. You | get that by multiplying the flux by the exposure time. | | So whichever exposure time gets you the 1.8 J/cm^2 is | enough to kill the flu virus and presumably SARS-CoV-2. | dillonmckay wrote: | Make sure you wear longsleeve clothes and sunglasses, so you do | not burn your skin or eyes! | sjg007 wrote: | Yeah I would expect a rise in HVAC installations. I was surprised | that cruise ships don't have them installed along with hepa | filters. | wool_gather wrote: | Interesting; is this a current practice? How do you get enough | exposure time to be effective in moving air? | mensetmanusman wrote: | By integrating over distance :) | outlace wrote: | Is it the seasonal changes in UV that make flu and similar | viruses less transmissible during the summer months? Maybe it has | nothing to do with temperature as some have suggested. | chrisco255 wrote: | It's been argued that both temperature and humidity make | viruses less transmissible. Not sure about the UV intensity. | Giorgi wrote: | So article says: "No" and then goes on to describe how it kills | virus. WTF | downerending wrote: | Crappy headlines are a major form of fake news. | | (I wrote to a major paper once to complain about this, and the | author of the article replied: _Well, I don 't write the | headlines._ Hooray.) | a3n wrote: | I wrote to the Denver Post once, and the editor replied "We | don't write the articles." It was a local story, but written | by the paper's owning entity, for publication in all of its | owned papers, including the Post where the incident happened. | I guess sort of like an in-house news wire "service." | | They do obviously write some of the articles that appear in | their paper. | [deleted] | ebg13 wrote: | Yes AND, despite the mongering in this article, UVC wavelengths | below 222nm have been found to be safe to mammalian skin. | | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552051/ | | https://journals.plos.org/plosone/article?id=10.1371/journal... | modeless wrote: | Wow, that's surprising, and exciting. If true, every room in a | hospital should have these lights. | 77pt77 wrote: | Let's start with copper doorhandles and bed-frames. | | Far better tested and understood. | dijit wrote: | It still takes 4hrs for copper to kill coronavirus. Why not | both? | dogma1138 wrote: | One of those is known not to cause long term adverse | effects. | m-p-3 wrote: | Interesting, thanks for sharing. | jiofih wrote: | From the linked paper: | | > the effect of chronic irradiation with a high dose of 222-nm | UVC to mammalian cells has not been determined | | Please be careful in announcing new truths based on your | interpretation of a couple papers. That's not how science is | done. | boomboomsubban wrote: | The tests on the SARS virus used 254nm wavelengths, which | deactivated the virus in fifteen minutes. Your sources both say | that that length causes severe damage, and both only tested | 222nm's ability to kill bacteria. A conclusive "yes" would need | testing done on a virus with the 222nm length. | jennyyang wrote: | Not only skin, but also eyes. You can look at Far-UVC light and | it won't hurt your eyes either. Whereas regular UVC light can | burn your eyes and cause temporary or permanent blindness. | [deleted] | mrfusion wrote: | I've always wondered. Why can't we put uv lamps in Hvac air | handlers? Especially on airplanes and cruise ships. | | I guess before there was no compelling reason to have the extra | cost but now it might be time to rethink it. | rini17 wrote: | UVC lamps produce ozone which is not healthy to breathe. | techsupporter wrote: | We can. Half a lifetime ago, I replaced the HVAC in my house | and one of the add-ons, which I bought, was a UV disinfecting | lamp. | | I have no idea if it was effective or snake oil but it was on | offer. Hospitals and medical labs have (demonstrably effective) | UV lights in their HVAC systems. | tzs wrote: | Slightly OT: numerous sources say that if the virus is on a | surface, it eventually dies (or deactivates anyway, if you don't | consider viruses alive in the first place). It can last up to 4 | days on glass, 3 on steel and plastic, and 24 hours on cardboard. | | What I've not seen explained and have no guess for is _why_ it | deactivates. It doesn 't have a metabolism. It doesn't consume | resources or use energy. It just sits there, a little spiky | spheroid surrounding some fragments of DNA or RNA. | | So what changes about it as it sits that causes it to deactivate? | saiya-jin wrote: | Just guessing - molecules of oxygen flying like crazy all | around (somewhere read on average 5km/s), eventually at one | point knocking something crucial off? | | At those scales, these things start to matter. | MikeAmelung wrote: | Just taking a shot in the dark here, but it likely just | disintegrates, probably from moisture and even friction from | air. That would explain why the "survival" is inverse to the | moisture-holding capability of the surface. | lisper wrote: | Entropy. A virus is simple by the standards of living things, | but it's still a pretty complicated system. There are lots of | random perturbations that can affect it ranging from quantum to | cosmic rays to chemical and thermal perturbations. All it takes | to deactivate a virus is to break one of its many critical | chemical bonds so that it can no longer reproduce. | | [UPDATE] Wow, five replies posted within two minutes of each | other! As other parallel replies have pointed out, oxygen is | very likely a significant factor here as it is plentiful and | very reactive. | ceejayoz wrote: | They dry out. | | https://www.usatoday.com/in-depth/news/2020/03/25/coronaviru... | | > In all settings, viruses need water to survive. "Viruses can | withstand a small amount of dehydration," says Dr. Paul | Meechan, a former director of safety at the Centers for Disease | Control and Prevention and president of the American Biological | Safety Association. | ChuckMcM wrote: | I believe this is the correct answer. My daughter with the | masters in biology also said this was the answer. | | Interesting side effect is that you can deactivate the virus | by putting it in a warm dry atmosphere. The warmth encourages | evaporation and drying. | | Sadly I don't have any equipment for doing viral particle | counts (was tempted to bid on some here: | https://www.equipnet.com/auctions/ but alas, I already have | way more EE test gear than I can use, no sense adding a full | bio laboratory to the mix :-). | | Even though I cannot prove its viability as a mitigation | solution, since I have a heat gun I spray my mail with 610 | degree F heat to ensure it is dry and warm (without exceeding | 452 degrees of course!) | [deleted] | wirrbel wrote: | the corona virus (similar to the HI virus) has an envelope | which is a lipid bilayer, there are viruses without an | envelope. Now you may think that a virus with an envelope is | more stable than viruses without, but the contrary is the case. | once the bilayer tears, the virus is dysfunctional. | | Also, what is not always talked about in the media currently | is, that not all viruses are replicated functional. In fact, a | large fraction of viruses produced are not capable of infecting | a cell in the first place due to replication errors, mutations, | etc. | whatshisface wrote: | > _what is not always talked about in the media currently is, | that not all viruses are replicated functional. In fact, a | large fraction of viruses produced are not capable of | infecting a cell in the first place due to replication | errors, mutations, etc._ | | I agree that people aren't writing news articles about that, | but why is it noteworthy that they're not? It doesn't matter | if only 1% of the virus particles on a surface are infectious | if there are millions of particles. | [deleted] | clumsysmurf wrote: | "SARS-CoV-2 RNA was identified on a variety of surfaces in | cabins of both symptomatic and asymptomatic infected passengers | up to 17 days after cabins were vacated on the Diamond Princess | but before disinfection procedures had been conducted" | | https://www.cdc.gov/mmwr/volumes/69/wr/mm6912e3.htm?s_cid=mm... | ceejayoz wrote: | RNA !== active virus. | | "Saying that live virus is there because viral RNA was found | is like saying I must be holding a meatball sub because | there's a marinara stain on my pants." - | https://twitter.com/kenjilopezalt/status/1242285123652825089 | tejtm wrote: | They disassemble, the atoms find lower energy states. | esahione wrote: | Oxygen and the atmosphere. | guardiangod wrote: | https://www.marketwatch.com/story/deadly-viruses-are-no-matc... | | _So why are surfaces different? The virus is held together by | a combination of hydrogen bonds (like those in water) and | hydrophilic, or "fat-like," interactions. The surface of fibers | or wood, for instance, can form a lot of hydrogen bonds with | the virus. | | In contrast, steel, porcelain or Teflon do not form much of a | hydrogen bond with the virus. So the virus is not strongly | bound to those surfaces and is quite stable._ | devy wrote: | The simple answer is it probably can, but the actual facts are | more nuanced than a simple confirmation. | | All bio-safety labs or hospitals or water treatment plants or | special HVAC systems have UV-C lamps to sanitize pathogens | because UV-C radiation destroying nucleic acids (DNAs / RNAs).[1] | However, the effectiveness really depends on the amount | exposure/energy level, light of sight(because UV-C doesn't | penetrate deep into objects), and even dust in the air or the on | the UV-C light lamps(which reduced the energy they emit) as well | as how DNA/RNA can be evolved or self-repaired. | | Anecdotally, Chinese hospitals are using UV-C lamp to sanitize | their medical equipments, masks (when it was in short supply | months ago) among other things. | | And yes, more exhaustive experiments should be conducted to | affirm this practice as it's the most non-toxic and energy | efficient way to sanitize surfaces. | | [1]: | https://en.wikipedia.org/wiki/Ultraviolet_germicidal_irradia... | | [2]: https://www.cnbc.com/2020/03/18/how-china-is-using-robots- | an... | dillonmckay wrote: | All water treatment plants do not use UV. | | It is actually fairly expensive. | | Some municipalities only use chlorine. My municipality only has | a 40 day supply of chlorine to treat the water. | | For such reasons, I purchased a whole-home UV-C water unit. | | Now, the wastewater plant uses UV-C, but its output is cleaner | than the drinking water input (river). | Scoundreller wrote: | Can also use ozone. One of Toronto's plants uses it and | treats about 20% of the city's water. Nice thing is that you | don't need railcars to arrive with it. | | https://www.toronto.ca/services-payments/water- | environment/t... | taborj wrote: | > I purchased a whole-home UV-C water unit. | | Got a link for the system you use? | makomk wrote: | It's not just Chinese hospitals that are using UVC to sterilize | masks, I think some US hospitals have started doing the same | thing due to the shortage there. | greedo wrote: | This is being pioneered in Omaha: | | https://www.unmc.edu/news.cfm?match=25283 ___________________________________________________________________ (page generated 2020-03-28 23:01 UTC)