[HN Gopher] Vitamin D Looks Powerful, Underutilized for Covid-19
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       Vitamin D Looks Powerful, Underutilized for Covid-19
        
       Author : lisper
       Score  : 38 points
       Date   : 2020-05-08 21:54 UTC (1 hours ago)
        
 (HTM) web link (agingbiotech.info)
 (TXT) w3m dump (agingbiotech.info)
        
       | cleandreams wrote:
       | Vitamin D is under studied because it cannot be patented (my
       | doctor told me).
        
         | ColanR wrote:
         | I've heard the same thing. No economic incentives compared to
         | making a custom drug.
        
       | gremlinsinc wrote:
       | Not by me. I'm D-deficient, had gastric sleeve surgery,
       | surprisingly it's the only deficiency I have regularly. I often
       | forget my D... but been taking it religiously and asked my doctor
       | if it's okay to add an extra 5000 iu per week, and he said it was
       | fine and a good idea because of how low I normally run.
       | 
       | I've got a new formulation coming soon though that has vitamin k
       | mixed in w/ 5000 ius, and a separate calcium/magnesium pill to
       | make sure my bones stay strong. Will get re-tested next month and
       | see if I beat the deficiency. I'm sure there's plenty of things
       | but seemed like taking D probably is biggest (other than
       | distancing) due to my already extremely low normal levels.
        
         | tracker1 wrote:
         | Worth considering if you're eating too little fat, you may have
         | problems with absorption of fat soluble vitamins like D and K.
        
         | httpsterio wrote:
         | I read somewhere that prolonged high doses of vitamin D might
         | have adverse effects on bone strength making them more brittle,
         | but I'm unsure about the source. I personally have celiac
         | disease and hypothyroidism am also having issues keeping the D
         | up (heh heh). I take about 200ug daily with vitamin K and I'm
         | thinking about increasing it temporarily to double of that.
         | Generally it shouldn't be an issue with short term higher
         | doses, but nearing a 1000ug daily dose for prolonged periods
         | (months) can be dangerous.
        
       | jeffdavis wrote:
       | And if people hoard it and it's out of stock, you can just go
       | outside!
        
         | samatman wrote:
         | It doesn't take hoarding, although that doesn't help. There are
         | precious few products that can stay on the shelves when
         | everyone decides they need some at once.
         | 
         | At northern latitudes, there isn't an available amount of
         | sunlight, such that dark-skinned people can synthesize a
         | healthy amount of vitamin D. Indeed, this is probably why light
         | skin is selected for at those latitudes.
         | 
         | As a silver lining, I hope this crisis will provoke awareness
         | of that fact. In most parts of the US, people with dark skin
         | should definitely be taking supplemental Vitamin D. Really
         | everyone should, unless they're a light-skinned sun-worshipper
         | living in the Sun Belt.
        
         | aklemm wrote:
         | My doctor told me plenty of Americans have trouble making
         | vitamin D even with sun exposure.
        
           | jeffdavis wrote:
           | Why is that? Is there some missing ingredient?
        
         | chvid wrote:
         | You can go outside and have a smoke ... that helps too ...
        
       | jeffdavis wrote:
       | A double-blind study for respiratory infections (before
       | covid-19):
       | 
       | https://www.bmj.com/content/356/bmj.i6583
        
       | Exmoor wrote:
       | Previous Vitamin-D/COVID discussion with many informative
       | comments: https://news.ycombinator.com/item?id=23023703
        
       | Alex3917 wrote:
       | For what it's worth, I've been curating research on over-the-
       | counter interventions for Covid-19 here:
       | https://www.reddit.com/r/covid19stack
       | 
       | The research on vitamin D has been discussed extensively there
       | over the last couple months.
       | 
       | This article (and the linked citations) misses a bunch of the
       | most important theorized mechanisms of action, most notably that
       | vitamin D plays a role in regulating blood clotting and having
       | adequate levels may prevent the kind of sudden deaths from stoke
       | we've been seeing in people who seemed to have gotten over the
       | disease with otherwise mild symptoms.
        
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       (page generated 2020-05-08 23:00 UTC)