[HN Gopher] Caffeine: A vitamin-like nutrient, or adaptogen
       ___________________________________________________________________
        
       Caffeine: A vitamin-like nutrient, or adaptogen
        
       Author : marttt
       Score  : 49 points
       Date   : 2020-05-24 18:07 UTC (4 hours ago)
        
 (HTM) web link (raypeat.com)
 (TXT) w3m dump (raypeat.com)
        
       | bob1029 wrote:
       | I've been off caffeine for going on 40 days now. Work/health were
       | suffering and I needed to hit the reset button. Some days its
       | rough, but on average the change is worth it now. Last week I was
       | able to deal with an extremely stressful event at work without
       | losing my calm. If I had been hopped up on my usual morning brew
       | under similar circumstances, I probably would have made some
       | serious career-altering mistakes (not necessarily my career).
        
       | mustachionut wrote:
       | People who aren't super healthy don't typically feel like
       | drinking lots of caffeine. I think that's a more likely
       | explanation than caffeine having tons of assorted health
       | benefits.
        
         | chrischattin wrote:
         | I think it's the opposite. People drink caffeine to mask an
         | unhealthy lifestyle - lack of sleep, hungover, poor diet,
         | sedentary, out of shape, etc.
        
       | simias wrote:
       | >Coffee drinkers have been found to have lower cadmium in
       | tissues; coffee making removes heavy metals from water.
       | 
       | How does that work? Where do the metals go?
       | 
       | Searching in the rest of the article I find:
       | 
       | >Coffee drinkers, for example, have been found to have lower
       | levels of cadmium in their kidneys than people who don't use
       | coffee, and coffee is known to inhibit the absorption of iron by
       | the intestine, helping to prevent iron overload.
       | 
       | I'm immediately suspicious of the way this is framed (I know many
       | people who suffer from lack of iron, I guess they should avoid
       | coffee). And what about the heavy metals then?
        
         | maxerickson wrote:
         | Presumably the metals are absorbed by the grounds.
        
         | 1MachineElf wrote:
         | Perhaps the diuretic effect of caffeine contributes to the
         | flushing out of all things, some heavy metals included?
        
         | ta17711771 wrote:
         | The beans, I'd imagine.
        
       | etaioinshrdlu wrote:
       | The funny thing is caffeine is produced by the plant to try to
       | poison herbivores. It's a very effective insecticide. So are
       | perhaps most other drugs made by plants.
        
         | dehrmann wrote:
         | It's the same thing with nicotine and capsaicin (we like these)
         | and cyanide (not so much).
        
       | sprusemoose wrote:
       | My teeth doctor told me it's bad for my teeth, so I now use a
       | straw to pumpjack my demon nectar
       | 
       | glorious feast
        
         | user982 wrote:
         | Are you sure they were warning about drinking it, and not its
         | effect of worsening bruxism?
        
         | DiabloD3 wrote:
         | He was incorrect based on the existing evidence.
         | 
         | Sugar-laden diets combined with both a mineral poor diet (ergo,
         | no dental remineralization) and a constant subclinical
         | dehydration (did you drink your gallon of water today? no?
         | saliva is the vehicle for said remineralization, and is one of
         | the first to be hit during early stages of dehyrdation; water
         | is required to maintain the pH of your mouth) is bad your
         | teeth.
         | 
         | The worst coffee can do is stain already poor enamel. Coffee is
         | hardly acidic, and its a myth that its more destructive.
         | 
         | Now, if you drink your coffee with sugar? _Thats_ bad, learn to
         | drink it black.
         | 
         | https://www.ada.org/en/~/media/ADA/Public%20Programs/Files/J...
         | 
         | Anything on this list that is below a pH of 5 you should
         | strongly avoid. pH is a log scale, so, pH of 5 is 10x worse
         | than 6, 4 is 10x worse than 5 or 100x worse than 6; the
         | hydroxyapatite in tooth enamel starts to dissolve at 5.5, and
         | coffee is only 5.11, well within your mouth's ability to
         | handle.
         | 
         | If he warned you because you suffer from bruxism, not because
         | of tooth decay, for most people, just follow the normal rules
         | for coffee that everyone else should follow: avoid caffeine 6
         | hours before bed.
        
           | sprusemoose wrote:
           | Thank you sir, I tip my hat and raise my Caffe latte to you~
        
           | gjs278 wrote:
           | hey we used to chat in #bitcoin-dev
        
         | dsego wrote:
         | You can also wash it away with a glass of water. It's common in
         | cafes to get a glass of water with coffee. After every sip of
         | coffee take a sip of water. This helps wit hydration as well.
        
           | omani wrote:
           | coffe does not dehydrate. that myth was debunked long time
           | ago.
           | 
           | the reason you get a cup of water to your coffe at cafes is
           | to drink the water BEFORE you drink the coffee. the water
           | helps to neutralize any (bad) taste in your mouth (eg after a
           | meal) so you can get the most out of the aroma of the coffee.
        
       | chrischattin wrote:
       | I have a theory that 50 years from now people will look back on
       | caffeine the same way we look back on everyone smoking in the
       | 50's. There were tons of "smoking is healthy" articles back then
       | too, and it was baked into the culture. Caffeine's negatives are
       | more hidden and second order effects that come from increased
       | cortisol levels, lack of sleep, adrenal fatigue, etc. I've done a
       | bunch of research on this and might write it up in a blog post
       | someday.
        
         | justinator wrote:
         | > write it up in a blog post someday
         | 
         | No time like the present! Brew up a pot, and get hammerin'! :)
        
       | DoreenMichele wrote:
       | The one thing that interests me in this piece is the bit about
       | cadmium and heavy metals and the references at the bottom don't
       | seem to list a study pertinent to this.
       | 
       | I've used "search page" and I've skimmed through all the titles,
       | but I have crap eyesight. So maybe I'm missing the reference.
       | 
       | But I would love to see good research relating caffeine or coffee
       | consumption to somehow helping with heavy metal issues.
        
         | ethbro wrote:
         | The initial phrasing about heavy metals sounded to me like it
         | was referring to the brewing process (without being specific as
         | to which one).
         | 
         | At first approximation, I'd be surprised if agitating heated
         | water in the presence of particular matter that increased its
         | acidity, then running it through a fine woven filter, didn't
         | have _some_ net effect.
         | 
         | As for the exact mechanism and efficacy, that's unfortunately
         | buried under 10,000,000 search results for coffee enema
         | products...
        
           | DoreenMichele wrote:
           | Yeah, I caught that. But I also chalked it up to "the most
           | defensible thing to say." It's part of why I would like to
           | see studies of some sort.
           | 
           | I've done a little googling myself and wasn't thrilled with
           | the results either, which is why I returned to the article to
           | look at its sources to see if I could find a better place to
           | start -- a thread to pull, if you will, to begin to unravel
           | this question. Good sources tend to lead to other good
           | sources, if only by telling you what sorts of phrases to use
           | in your next search.
        
       | acituan wrote:
       | I can help but feel lied to when there is only a laundry list of
       | "good"s and no analysis on downsides.
       | 
       | When I read "it helps with this" "it prevents this", I always ask
       | "but at what cost". Can an exogenous molecule that was so
       | adaptive be missed this bad and now consuming it will just fill
       | that gap we had for millions of years?
       | 
       | Let's not kid ourselves. Concentrated caffeine is a drug and not
       | a nutrient. We drink it because it is psychoactive and we
       | habituate to it. Try drinking redbull as a caffeine-naive person
       | or not drinking coffee as a daily drinker. If an exogenous
       | substance is that potent, it is a drug. (Even though I like it
       | myself too, it is also pretty shit of a drug in my opinion, with
       | 5 hr half-life, a dice roll every time whether it is gonna create
       | more sleep than focus and a steep tolerance curve.) Magic
       | mushrooms also have nutritional value, nicotine also has some
       | benefits, beer has tons of calories, they might even have
       | adaptive value with occasional use. You might enjoy them, you
       | might drink coffee everyday. That is fine. But they are all drugs
       | and not nutrients.
        
         | ip26 wrote:
         | _Can an exogenous molecule that was so adaptive be missed this
         | bad and now consuming it will just fill that gap we had for
         | millions of years?_
         | 
         | Maybe we didn't have a gap for millions of years. The African
         | kola nut contains caffeine and is supposedly a popular
         | stimulant.
        
           | acituan wrote:
           | That was exactly my point. The molecule is not novel. It
           | indeed existed and we had the opportunity to evolve with its
           | ambient presence. If the laundry list of advantages were that
           | important, it would have created selective pressure on those
           | who didn't consume it. But it didn't prove itself as
           | indispensable while other nutrients did; that's why they are
           | nutrients and caffeine isn't.
        
             | Mirioron wrote:
             | We don't need (many) carbs either, yet it's the biggest
             | part of our diet and has been for a long time. We still
             | call it a nutrient.
        
             | nootanond wrote:
             | >It indeed existed and we had the opportunity to evolve
             | with its ambient presence.
             | 
             | It may exist in a number of plants all over the world but
             | that doesn't mean that people were harvesting and using it
             | outside of certain isolated cultures until fairly recently,
             | compared to evolutionary timescales.
             | 
             | If anything I'd expect significant genetic variation
             | representing adaptations only present in some groups.
             | 
             | https://pubmed.ncbi.nlm.nih.gov/20859791/
        
         | dehrmann wrote:
         | > no analysis on downsides
         | 
         | The main one has to be worse sleep quality.
        
         | frant-hartm wrote:
         | >a dice roll every time whether it is gonna create more sleep
         | than focus
         | 
         | This is highly individual. There are people who can go to sleep
         | after drinking a cup of coffee, who feel sleepy after drinking
         | small amount (how small actually varies) and then people like
         | me that can go on for 5 more hours no matter how tired, even
         | after being awake for more than 24 hr - there is no dice roll,
         | works 100 %.
        
           | eloff wrote:
           | That you can sleep does not imply you get the same quality of
           | sleep. It's well known that alcohol and caffeine reduce sleep
           | quality. So even if you can sleep after having a coffee, it's
           | probably still not a good idea. Have a decaf if it's after
           | 3pm.
        
         | johnfn wrote:
         | > I can help but feel lied to when there is only a laundry list
         | of "good"s and no analysis on downsides.
         | 
         | Keep in mind that there's a strong selection bias here. We've
         | been drinking coffee for hundreds of years. If over that time
         | we had ever noticed it had any notable negative side effects,
         | we would have relegated it to the very very long list of
         | substances which are more of a mixed bag.
        
           | tcbawo wrote:
           | For many people, caffeine causes high blood pressure,
           | anxiety, and in extreme cases heart arrythmia.
        
             | nootanond wrote:
             | In the short term over the duration of effect. I don't
             | think I've ever seen a reliable study that demonstrated any
             | reliable evidence of long term harm from coffee with any
             | certainty.
        
         | BurningFrog wrote:
         | I think of it as a drug that adapts us to modern industrialized
         | life, while our genetic dispositions are still half in the
         | hunter/gatherer stage.
        
           | 01100011 wrote:
           | Sort of like nicotine. I don't think we would have made the
           | transition to desk work as easily as we did without it. I'm
           | pretty sure the US space program depended on it.
        
       | joemazerino wrote:
       | Coffee and caffeine are not mutually exclusive. Coffee is one of
       | the best drinks for antioxidants (without milk). Caffeine in
       | large quantities is bad for the health. Moderate and experiment.
        
       | andy_ppp wrote:
       | I love caffeine and coffee! I used to drink two to three cups per
       | day but for the last 6 months I've been feeling rather unwell
       | when taking it; I start getting sweaty hands, shakes, heart
       | palpitations, and start feeling sick and anxious shortly
       | afterwards. I would love to be able to keep drinking coffee but
       | the price is now too high! I have been drinking decaf coffee
       | which is okay but I miss the real thing. If anyone knows a way I
       | scan keep my caffeine buzz without the above I'd love to know...
        
         | ip26 wrote:
         | Check your condition- are you getting enough sleep, food,
         | water? Are you consuming it late in the day and reducing your
         | sleep quality? What about your dose, has it grown?
         | 
         | I experience the worst side effects when I've been fasting too
         | long, or drink it late in the day.
        
         | amelius wrote:
         | Taurine, [1].
         | 
         | Or eat a banana, [2].
         | 
         | [1] https://www.mayoclinic.org/healthy-lifestyle/nutrition-
         | and-h...
         | 
         | [2] https://www.hindustantimes.com/health-and-
         | fitness/overcaffei...
        
         | on_and_off wrote:
         | have you tried mushroom coffee ?
         | 
         | I don't suffer from the downsides of coffee so I don't even
         | have anecdotal experience on this but it sounds like it is
         | worth a shot.
        
         | Honga wrote:
         | Matcha tea has a bunch of stuff that is supposed to suppress
         | the negatives of caffeine and keep the positives.
         | 
         | Also the taste is strong enough to be a decent coffee
         | replacement.
        
           | dionian wrote:
           | L-Theanine? goes great with coffee (not mixed, just taken
           | near the same time) - smooths out the jitters. Probably why
           | Tea is more 'calming'
        
             | d33 wrote:
             | Could you point to any research? I asked many doctors but
             | nobody really knew about the substance nor could tell me
             | whether it's safe to supplement.
        
               | gjs278 wrote:
               | that's because doctors are retards. it's safe. it's an
               | amino acid. it's commonly mixed with caffeine. be your
               | own doctor and look it up on examine.com
        
               | bavell wrote:
               | FWIW, 200mg of L-Theanine is included in my workout
               | recovery supplement. Research seems sparse but here's
               | what they say about it: (scroll down, click ingredients
               | tab) https://athleanx.com/athleanrx/reconstruxion
        
       | baxtr wrote:
       | Anyone wondering: The summary is that Caffeine seems to be very
       | good for your health! So keep on drinking
        
         | amelius wrote:
         | There is more in coffee than caffeine. For example cafestol is
         | a substance present in unfiltered coffee that is known to cause
         | health problems.
         | 
         | https://en.wikipedia.org/wiki/Cafestol
        
       | mcnamaratw wrote:
       | I like coffee. Let's skip the marketing words and look at the
       | data.
        
       | DabbyDabberson wrote:
       | a "nootropic" in modern parlance
        
       | mcculley wrote:
       | I am impressed at the lengths people will go to rationalize
       | consuming that to which they are addicted.
        
         | standardUser wrote:
         | I am an avid coffee drinker and a former cigarette smoker.
         | While I won't deny that caffeine is addictive, the addictive
         | power is so mild that it's mostly irrelevant. I skip having
         | coffee on some days accidentally. The idea of accidentally
         | going a day without smoking a cigarette is unfathomable. The
         | times I've gone without coffee for a few days or weeks I have
         | felt a little bit sluggish. The times I have gone days or weeks
         | without smoking were nightmarish ordeals that consumed my every
         | waking thought. Point being, I would be very careful to assume
         | things about 'addiction' when it's a phenomenon comes in so
         | many shapes and sizes.
        
           | pengaru wrote:
           | I'll match your single sample of anecdata as a previous
           | smoker from the midwest and occasional coffee drinker:
           | 
           | I never found nicotine addictive. It never compelled me to
           | increase my consumption beyond a few cigarettes a day,
           | usually in social settings. I never became a regular
           | purchaser of cartons of cigarettes. It was purely a social
           | activity as most my peers were smokers and participating in
           | the smoke breaks was a huge part of socializing. But it never
           | escalated beyond that, there was simply no draw and stopping
           | cold-turkey was completely uneventful with zero physiological
           | effects.
           | 
           | Coffee however, has such a profoundly stimulating effect on
           | me, it completely derails my life for days after a lone day
           | of consumption. It's a very on-vs-off modal existence, and if
           | I fall into the on mode for more than a couple contiguous
           | days, I begin craving it and actively seeking it out. And
           | when I manage to finally resist those cravings, I end up
           | going through ~three days of hangover-like withdrawal hell
           | which if I'm not up for enduring will just push me back on
           | the wagon to make it stop.
           | 
           | For me, coffee/caffeine is far more sinister and addictive
           | than cigarettes.
        
         | whyhow wrote:
         | I think it is wrong to assume that something is inherently bad
         | just because it is addictive.
        
           | Jarmsy wrote:
           | What definition of addiction are you going by? Most seem to
           | include some mention of 'despite adverse effects' or similar.
           | Otherwise isn't it just dependence?
        
         | Barrin92 wrote:
         | I think in particular with coffee there is if anything the
         | opposite cultural bias. Being German, there's a popular Canon
         | (loosely translated)
         | 
         |  _" don't drink coffee, coffee! The Turkish potion is not for
         | kids, weakens the nerves, makes you pale and sick. Don't be a
         | muselman (muslim, archaic), who can't do without it"_
         | 
         | My almost 90 year old grandmother still talks like this about
         | coffee and many people forget nowadays how bad of a reputation
         | coffee had in the West until it got really popular, and despite
         | not having many obvious bad health effects, and maybe even
         | having positive ones.
        
           | JanSt wrote:
           | I'm german and I have never heard that. Coffee has a great
           | reputation and pretty much everyone I know drinks it. It's
           | more of a social stigma not to.
        
             | Barrin92 wrote:
             | that's surprising and I guess you're relatively young and
             | don't have kids because I've actually still heard it sung
             | by kids in kindergarden. There's also Bach's coffee Cantata
             | in a similar vein, and quite a lot of fiction dictated to
             | the allegedly detrimental effects of drinking coffee.
             | 
             | And sadly often a lot of it is tied to the image of the
             | "sickly Turk" which is a popular stereotype attached to
             | most things imported from 'oriental' cultures. You may
             | remember debates about the hookah craze a decade ago or so.
        
         | bryanrasmussen wrote:
         | It is difficult to get a man to understand something when his
         | morning cup of coffee depends upon his not understanding it.
        
         | cc81 wrote:
         | I don't know. I can feel a slight dependence on caffeine if I
         | have been drinking a lot during some weeks and then stopping
         | cold turkey (slight headache, possibly slightly more tired in a
         | day or two) but it does not feel very addictive.
         | 
         | For a long period of time I only drank coffee during the week
         | and not weekends, sometimes I stopped some summers and when I
         | slept badly I stopped drinking coffee for a while. No problem
         | at all with any of that.
         | 
         | I do like like the small energy burst in the morning when I'm
         | working and I like the ritual when it is winter in Sweden it is
         | dark and cold outside and you are freezing, then drinking a cup
         | of coffee as you start up your computer is nice.
        
           | JanSt wrote:
           | I have cycled between heavy consumption and no coffee intake
           | at all. On the first few days I often had headaches and felt
           | slightly depressive (I'm pretty much never feeling depressive
           | otherwise) and unproductive. After a week or so off of
           | caffeine I start to feel great until I restart my coffee
           | habit (the first few days are amazing; it just tastes too
           | good; it is social to drink coffee with friends, family and
           | coworkers; etc.)
        
       ___________________________________________________________________
       (page generated 2020-05-24 23:00 UTC)