[HN Gopher] Mosquitoes kill more than 700k people every year
       ___________________________________________________________________
        
       Mosquitoes kill more than 700k people every year
        
       Author : gregd
       Score  : 175 points
       Date   : 2020-05-29 16:03 UTC (6 hours ago)
        
 (HTM) web link (www.isglobal.org)
 (TXT) w3m dump (www.isglobal.org)
        
       | ChrisMarshallNY wrote:
       | When I lived in Africa -especially Nigeria- there were these
       | swarms of mosquitoes that could drain half a pint of blood in a
       | minute or two.
       | 
       | My sister got caught in one of them. Not fun. She was _covered_
       | in the little bastards.
        
         | foobiekr wrote:
         | One time, while hiking to go bass fishing in the high Uintas, I
         | got attacked by a swarm of mosquitos so insane that they were
         | trying to bite me through my shirt, through my shorts, my face
         | was covered and one of the little bastards managed on land on
         | my cornea. Nightmarish.
        
       | shoulderfake wrote:
       | fucking snakes, hate em
        
       | asdf21 wrote:
       | Way more than that if you count diseases from ticks.
        
         | [deleted]
        
       | [deleted]
        
       | Koshkin wrote:
       | To put this in a perspective,                  1 Mosquito
       | 1,000,000        2 Human            475,000        3 Snake
       | 50,000        4 Dog               25,000        5 Tsetse Fly
       | 10,000        6 Assassin Bug      10,000        7 Freshwater
       | Snail  10,000        8 Ascaris Roundworm  2,500        9 Tapeworm
       | 2,000       10 Crocodile          1,000       11 Hippopotamus
       | 500       12 Elephant             100       13 Lion
       | 100       14 Wolf                  10       15 Shark
       | 10
       | 
       | https://www.worldatlas.com/articles/the-animals-that-kill-mo...
        
         | holbue wrote:
         | Would love to see statistics from the other perspective: Which
         | animals are killed most by humans? Besides insects, I would
         | guess fish and chicken are quite high...
        
           | agumonkey wrote:
           | you mean farmed animals or wild ones ?
        
             | derefr wrote:
             | In that case, depending on the framing, you might care more
             | about the balance of animals killed by humans vs. animals
             | caused-to-exist by humans. (Or you might think both of
             | those things are bad. Negative utilitarians don't much like
             | chicken farming, given the large number of chicken lives
             | and the large amount of suffering in each life.)
        
         | morsch wrote:
         | 0 Traffic        1,350,000
         | 
         | Sort of weird to limit the Human category to, apparently,
         | conflict, war, murders, and acts of terrorism. Also, it's
         | horrible that conflict, war, murders, and acts of terrorism are
         | in the same ballpark as traffic deaths.
         | 
         | https://en.wikipedia.org/wiki/List_of_countries_by_traffic-r...
         | (2016)
        
           | robbrown451 wrote:
           | Personally I think they should just skip the human category.
           | I mean, if I die of old age aren't I sort of being killed by
           | a human? ok maybe that is a stretch, but how about if I catch
           | the flu from another person? Is it the flu or the other
           | person that got me?
        
             | xpe wrote:
             | Here is what the article from worldatlas.com meant, in
             | context:
             | 
             | > Approximately 475,000 people die every year at the hand
             | of fellow man. In a world filled with conflict, war,
             | murders, and acts of terrorism, this is unfortunately not
             | that surprising. Deaths among humans are intentional and
             | pre-calculated making them beyond tragic.
        
           | derefr wrote:
           | The human category is limited, I believe, to intentional
           | killing. Otherwise you open up a whole can of worms about
           | macroeconomic trolley problems. (Am I killing people _right
           | now_ by making insufficiently-optimal donations to charity?)
        
             | paulsutter wrote:
             | What makes you think mosquitos are deliberately spreading
             | malaria?
        
               | jayrot wrote:
               | One of them told me so.
        
             | brenden2 wrote:
             | Presumably if you're speeding or driving while intoxicated,
             | you're doing so intentionally. It's not as if someone is
             | forcing you to drive too fast or too drunk. These things
             | (especially speeding) dramatically increase the likelihood
             | of being in a collision.
        
               | [deleted]
        
             | viburnum wrote:
             | A million people killed by cars prevents five million from
             | dying how?
        
             | bredren wrote:
             | It doesn't have to be this abstract, though. This will
             | likely change in the next 20 years.
             | 
             | Consider the move from horse drawn carriages to vehicles.
             | 
             | It was an acceptable risk that anyone might be permanently
             | disabled due to being kicked in the head or trampled by a
             | horse.
             | 
             | This might be a horse you are simply walking past. Or one
             | that is spooked and running down the street. The owner of
             | the horse beared little to no responsibility.
             | 
             | Now it is largely acceptable, to permanently disable or
             | kill someone due to a mistake or some form of common
             | negligence while operating a vehicle.
             | 
             | It is almost not a crime to accidentally run someone over.
             | This is "normal" or "not intentional."
             | 
             | In the future, it will seem insane to have allowed so many
             | people manual control over multi-ton vehicles.
             | 
             | Just as it does not make sense that a horse would be tied
             | up outside Trader Joe's and due to a spook permanently
             | disable you as you exit the store.
             | 
             | It will seem so primitive to have such loose controls on
             | cars that if you chose to drive a manually controlled car
             | killing someone will likely be seen as dangerous enough of
             | a choice that a person would be held liable for
             | manslaughter.
        
               | derefr wrote:
               | I don't disagree with the principles you're standing up
               | for here; but we're not having an ethical argument, we're
               | talking about what went into the author's analysis. And
               | AFAICT, in said analysis, they just took for "human
               | deaths caused by humans", the set of deaths where one
               | human thought "I want that other human to die", and then
               | caused that to happen. Situations with legal _mens rea_
               | for killing.
        
               | jbay808 wrote:
               | Ok, but that makes it incompatible for comparison with
               | the other animals killing humans. In some cases maybe
               | (sharks, wolves, lions, crocodiles) the animal could be
               | actively wanting the human to die, but in others
               | (freshwater snails, tapeworms, mosquitoes), that's
               | probably not the case.
        
               | lxmorj wrote:
               | Peace talks sometimes work. Asking sharks to tone down
               | the chomping does not. There is no point to
               | differentiating 'attack vs incidental' animal deaths in
               | the same way as w humans...
        
             | gedekran wrote:
             | Or the amount of people you just killed by writing this
             | comment. Or me, I'll never be able to live with the
             | shame...
        
         | lostmsu wrote:
         | Huh, venomous spiders are not on the list?
        
           | NikkiA wrote:
           | They rarely kill, just 'really annoy' for a month or so.
        
         | slg wrote:
         | These numbers are weird. Why do we count mosquito-borne
         | diseases under mosquitoes but don't put communicable diseases
         | under the tally for humans? It is especially curious
         | considering mosquitoes don't know any better while humans have
         | both the knowledge and ability to dampen how disease spreads
         | through our population.
        
           | ravenstine wrote:
           | That's kind of like saying that it's not the shark that kills
           | people but the blood loss.
        
             | dubcanada wrote:
             | Not it's not.
             | 
             | They're saying that 1,000,000 is the number for mosquitos,
             | not because they kill people but their a carrier of
             | disease.
             | 
             | What they are asking is do we consider other animals in the
             | same capacity, such as, does the number beside humans
             | include human transmittable diseases (HIV for example).
             | 
             | Seems like a reasonable question.
        
               | ravenstine wrote:
               | > Seems like a reasonable question.
               | 
               | Just to be clear, I think it's a perfectly reasonable
               | question. A rational question can still contain a
               | potential flaw.
               | 
               | But I did misunderstand what they were asking.
        
             | slg wrote:
             | You missed my point. I am asking for consistency in the
             | metrics.
             | 
             | We get malaria from a parasite that is spread by
             | mosquitoes.
             | 
             | We get tuberculosis from a bacteria that is spread by
             | humans.
             | 
             | TB kills more than three times as many people every year as
             | malaria. Why is malaria counted as a death caused by
             | mosquitoes but TB isn't a death caused by humans? Either
             | you count both or you count neither.
        
               | godelski wrote:
               | Mosquitoes don't kill except for diseases. Humans have
               | means of killing besides spreading diseases.
        
               | bryanrasmussen wrote:
               | I think it's because the only really meaningful
               | experience you have with a mosquito is when it kills you
               | via malaria.
        
               | [deleted]
        
               | ravenstine wrote:
               | Ah, I see.
               | 
               | It is probably fair to count TB deaths in the "human
               | kills" category, but I think we usually make a
               | differentiation between human to human disease and
               | disease caused by contact with an animal. It's just the
               | way we see ourselves as separate from the rest of the
               | animal kingdom.
               | 
               | Although I get what you're saying, I don't think that
               | human deaths caused by TB is necessarily what people are
               | interested in when you aggregate all of the of humans at
               | the hand of other humans, which may be why those deaths
               | are omitted.
        
           | asdfasgasdgasdg wrote:
           | For one thing, we could conceivably get rid of the mosquitoes
           | if the problem to solve is making life better for humans.
           | However, getting rid of humans to make life better for humans
           | rather defeats the purpose.
        
             | slg wrote:
             | Tuberculosis kills almost as many people as the rest of
             | that list combined. It is spread from human to human. There
             | is a vaccine that can help prevent it. If this list was
             | intended to shine light on a fixable problem, TB seems like
             | a much easier problem to solve than eradicating all
             | mosquitoes.
        
         | jariel wrote:
         | This is unfair because Mosquitos don't kill anyone. They are a
         | vector for pathogens that kill.
         | 
         | Humans are also vectors for pathogens, we just don't count them
         | as such.
        
         | sarabande wrote:
         | Off topic, but how did you make that beautifully formatted
         | table?
        
           | xpe wrote:
           | See:
           | https://news.ycombinator.com/newsfaq.html
           | 
           | which has a link to:
           | https://news.ycombinator.com/formatdoc
        
           | Koshkin wrote:
           | Insert two spaces at the beginning of each line.
        
             | sarabande wrote:
             | Testing (edit, it didn't work when I copied it from the
             | page and added two spaces before each line, see below):
             | 1 Mosquito 1,000,000       2 Human 475,000       3 Snake
             | 50,000       4 Dog 25,000       5 Tsetse Fly 10,000
        
         | creaghpatr wrote:
         | I had never heard of Assassin bug but apparently they are all
         | over North America.
         | 
         | https://www.insectidentification.org/insect-description.asp?...
         | 
         | Wonder if those Murder Hornets will make next year's list?
        
           | spijdar wrote:
           | My understanding from (very briefly) reading about the insect
           | family Reduviidae is some species are parasitic and spread
           | deadly pathogens much the same way mosquitoes do. It's not
           | the insects themselves killing people, but diseases like
           | Chagas disease (Triatominae is a subfamily of Reduviidae
           | "Assassin Bug"). [1]
           | 
           | [1] https://www.paho.org/en/topics/chagas-disease
        
           | gnulinux wrote:
           | > Wonder if those Murder Hornets will make next year's list?
           | 
           | I was curious, so:
           | 
           | > Since 2001, the yearly human death toll caused by stings of
           | bees, wasps and hornets in Japan has been ranging between 12
           | and 26.[26] Since this number also includes deaths caused by
           | wasps, bees, and other hornet species, the number of deaths
           | caused by Asian giant hornets is likely to be significantly
           | lower.[citation needed]
           | 
           | from:
           | 
           | https://en.wikipedia.org/wiki/Asian_giant_hornet
           | 
           | [26] is a Japanese source that I cannot read.
           | 
           | Seems like they're not a huge threat?
        
           | the_af wrote:
           | The assassin bug is called "vinchuca" in my country,
           | Argentina, and it's a real problem here. There are ways to
           | combat the bug, but once you catch the Chagas disease,
           | there's no cure and you have to live with it. There is only
           | symptomatic treatment as far as I know.
        
           | wetmore wrote:
           | When I was a kid at camp we used to catch them and make them
           | fight other bugs. Those things are creepy.
        
         | stevenbruce569 wrote:
         | How about polar bears or orcas - and how would you know?
        
         | fuckyah wrote:
         | Let's get rid of mosquito and human. Problem solved ;D
        
         | elwell wrote:
         | Why isn't "Plasmodium parasites" on this list?
        
         | ghshephard wrote:
         | And, in the United States - the most lethal animal of all is
         | the ... Deer. (about 120 deaths/year, which shows how safe most
         | Americans are from animals)
         | 
         | https://www.askmen.com/news/entertainment/deers-kill-more-pe...
        
         | cameronfraser wrote:
         | Poor sharks, they get one of the worst raps for how little
         | damage they do to humans. I'm surprised to see dogs so high up
         | on that list.
        
           | aclsid wrote:
           | Well, think about it. A mosquito bite seems harmless, while
           | getting torn to pieces by a shark, in a medium where you
           | cannot even run it is scary as hell.
        
           | agumonkey wrote:
           | That's just like flight safety records.. the issue with
           | sharks is that when something happens you're 99% about to
           | lose a limb or life.
           | 
           | You run into mosquitoes 30k times a year, one of them may
           | kill you, and most of the time you could have saved yourself
           | on your own.
        
             | jayrot wrote:
             | Uhh, maybe? Shark attacks are quite rare, but I think you
             | might be underestimating how many bites just result in
             | stitches. Talking about "shark attacks" here. Not "Great
             | White shark attacks". Likewise you're certainly
             | underestimating how many airplane "accidents" don't result
             | in any injury (again, not talking about "commercial airline
             | accidents").
        
           | twothamendment wrote:
           | Yeah, I'd rather have a neighbor with a shark than a neighbor
           | with a dog.
        
           | JoeAltmaier wrote:
           | I'm thinking, that data is more of a heat-map of
           | interactions. Any human interaction with a shark in its
           | environment, shark wins. So as a per-capita, they might be
           | near 100%?
        
             | jayrot wrote:
             | I know it's not the point you were trying to make but
             | 
             | > Any human interaction with a shark in its environment,
             | shark wins.
             | 
             | this is straight-up wrong. Humans and sharks interact all.
             | the. time. They're not killing machines.
             | 
             | I imagine you probably know that, so I'm not trying to
             | patronize you (honestly). But this is really important.
             | 
             | SHARKS KILLED 4 HUMANS IN 2018. HUMANS KILLED 100 MILLION
             | SHARKS IN 2018.
             | 
             | https://www.usatoday.com/story/news/world/2019/01/28/shark-
             | a...
        
             | jacobr1 wrote:
             | I'm not sure. Plenty of people swim in waters where sharks
             | are regularly observed. And still the attacks are low. And
             | further, with many attacks, I think in particular great-
             | whites, they back off after the first bite, which allows
             | for much greater survivability. So the ratio of "shark
             | contact" to "sharks win" is probably low. And if you also
             | add in fishing for sharks (such as for fins) humans
             | probably kill a lot more sharks than the other way around.
        
               | JoeAltmaier wrote:
               | Hm. Not convinced. Contact with sharks vs contact with
               | mosquitoes, or with dogs, or anything else on that list?
               | 
               | Most people spend maybe hours a year in shark ecosystem.
               | Vs 365 days a year in dog country, or mosquito etc.
        
               | sosborn wrote:
               | > Contact with sharks vs contact with mosquitoes, or with
               | dogs, or anything else on that list?
               | 
               | Swimming with reef sharks vs taking a hike in a malaria
               | infested jungle? Swimming with reef sharks please.
        
               | tempestn wrote:
               | Certainly the amount of contact plays a roll. That's why
               | dogs are so much higher than wolves for instance. But
               | it's also true that most of the time people spend
               | swimming around sharks, they don't get bitten. How the
               | ratio of attacks to contacts compares between sharks and
               | dogs or other animals I don't know; agreed that would be
               | somewhat interesting!
        
           | tomohawk wrote:
           | The dog attacks are really more about dogs that have rabies.
           | 
           | In countries that have good rabies control this is not an
           | issue. For example, the US has 30 - 50 deaths due to dogs
           | each year.
        
           | Cactus2018 wrote:
           | Gruesome wikipedia page with detailed _Circumstances_
           | 
           | https://en.wikipedia.org/wiki/List_of_fatal_dog_attacks_in_t.
           | ..
           | 
           | The pattern appears to be, very young child, or older adult,
           | attacked by either a pitbull or pack of dogs.
        
           | jl6 wrote:
           | I suspect dogs aren't particularly deadly, it's just that
           | there are so many of them and they collectively spend so much
           | time near humans. Sharks on the other hand almost never
           | interact with humans.
        
             | thrwaway69 wrote:
             | I am not sure about that. In developing countries, rabies
             | kill a lot of people. They might not directly kill people
             | as much but their bites sure do.
             | 
             | https://www.newindianexpress.com/lifestyle/health/2020/jan/
             | 1...
        
             | csours wrote:
             | The only reason housecats aren't at the top of the list is
             | that they are so small.
        
               | gpderetta wrote:
               | Or they cover their tracks very well!
        
           | chubot wrote:
           | _There Are No Such Thing As Shark Attacks_
           | 
           | https://www.underwatertimes.com/news.php?article_id=03214697.
           | ..
           | 
           | I actually saw this standup bit recently and after Googling,
           | it looks like it was borrowed ...
           | 
           | https://www.youtube.com/watch?v=RLwYkZUNvKo&feature=youtu.be.
           | ..
           | 
           | To clarify, it's actually the other way around, the standup
           | came BEFORE the blog. Should have realized the upload date is
           | not the performance date.
           | 
           | https://www.espn.com/blog/truehoop/post/_/id/3722/shark-
           | atta...
        
           | quicklime wrote:
           | https://xkcd.com/795/
        
             | saghm wrote:
             | I was expecting this one before I clicked:
             | https://xkcd.com/1252/
        
         | globular-toast wrote:
         | This list isn't really fair. Mosquitoes don't actually kill
         | people, they are just vectors for a disease which does kill
         | people. So then humans should get a point for every death due
         | to flu, AIDS or COVID-19, right? And all the accidental deaths
         | too, because I'm pretty sure the mosquitoes are just living and
         | don't intend to kill anyone. So I think human should be number
         | 1 by a very long way, followed by mosquito.
        
         | ravenstine wrote:
         | Is it most mosquitoes, or is it primarily aedis aegypti? I
         | could swear I read that particular species was responsible for
         | most mosquito-bourne disease, but I can't seem to find much
         | information for the proportion between it and other species.
         | 
         | If they disproportionally kill even more than other mosquitoes,
         | that also puts things into greater perspective. Perhaps if we
         | could target this particular species, it would save millions of
         | human lives.
        
           | dekhn wrote:
           | From Project Debug, Verily's attempt at reduction of mosquito
           | problems: https://debug.com/
           | 
           | """Mosquitoes kill more people than every other animal
           | combined. One species, Aedes aegypti, carries diseases such
           | as dengue, Zika, yellow fever, and chikungunya which make
           | hundreds of millions of people sick every year"""
        
           | DaniFong wrote:
           | i know someone who wants to do this, and probably can.
        
             | divbzero wrote:
             | Is that "someone" funded by the Gates Foundation? [1] [2]
             | 
             | [1]: https://www.gatesnotes.com/Health/Mosquito-Week-2018
             | 
             | [2]: https://www.geekwire.com/2018/gates-foundation-teams-
             | oxitec-...
        
       | madengr wrote:
       | Hydroxychloroquine has been used as a malaria preventative for 60
       | years. Now it is suddenly unsafe?
        
         | hobs wrote:
         | Malarone is also a malaria preventative, and I personally had a
         | psychotic break while taking it, it took 8 men to hold me down
         | and strap me a bed for two days until I came to.
         | 
         | Seems pretty harmless I guess?
        
           | Nasrudith wrote:
           | The disturbing thing is compared to some of the alternatives
           | which can stop breathing in some people that is safer.
        
           | Mediterraneo10 wrote:
           | The antimalarial prophylaxis which is infamous for mental-
           | health disturbances is lariam (mefloquine). Are you sure you
           | weren't taking that instead? When malarone appeared on the
           | market, one of its big selling points was that it does not
           | have the drawbacks of lariam (or doxycycline).
        
             | hobs wrote:
             | You know, I am not 100% sure, the time beforehand is pretty
             | foggy and they both have an m name it makes me question the
             | memory... it was many years ago.
        
           | DoofusOfDeath wrote:
           | If you don't mind, could you say a bit more about the
           | psychotic break? The closest thing from my own experience is
           | being told that I thrashed around a lot while coming out of
           | post-surgery anesthesia, but I have no memory of it.
        
             | throwanem wrote:
             | General anesthesia often has this effect on both sides,
             | because muscle tone is lost late in induction and regained
             | early in recovery. If you've been surprised to find
             | yourself wrapped snugly in a sheet just before being put
             | under, this is why.
             | 
             | It's not related to the sort of mental effects of
             | antimalarials mentioned in GP's comment.
        
             | hobs wrote:
             | I remember having a sundowner, talking with my family and
             | slowly getting more and more irritated about some minor
             | conversational bit someone said.
             | 
             | I clearly remember starting to get louder and more
             | aggressive and then I blacked out. I woke up in a pool of
             | my own sweat several days later wondering what had
             | happened.
             | 
             | People talked to me about what happened I piece together
             | bits and pieces floating around in a red haze and having a
             | human pile on top of me.
             | 
             | In retrospect the weirdest part was how readily they
             | accepted I was sane again.
        
         | nunodonato wrote:
         | we live in times of extreme double-standards. no point in
         | discussing it or will be downvoted and criticized to oblivion
        
           | melling wrote:
           | No, malaria drugs have been long known to have side-effects.
           | 
           | https://my.clevelandclinic.org/health/drugs/19772-hydroxychl.
           | ..
           | 
           | Here's a 2013 NIH article about a rare heart condition.
           | 
           | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760572/
        
         | nanodeath wrote:
         | I can't tell if this is a troll comment. The article makes no
         | mention of hydroxychloroquine.
        
           | madengr wrote:
           | Well it's a troll article. I might as well post an article
           | about lead paint being dangerous.
        
         | SketchySeaBeast wrote:
         | I don't know where that was mentioned in the article, so I
         | think we're going off topic, but isn't the use of cures weighed
         | against their efficacy and danger? No one would suggest
         | chemotherapy for a cold.
         | 
         | Hydroxycholorquine has proven to be effective against Malaria,
         | which is terrible and can be deadly, but proven ineffective and
         | in fact can make worse COVID, so it's not recommended to be
         | used there. Makes sense to me.
        
           | madengr wrote:
           | It's been shown to have no benefit when someone is near-dead
           | from COVID. Don't 80% of people on ventilators die anyway? So
           | ventilators have no benefit. From what I have been reading,
           | the drug does have benefit when used as a prophylactic, in
           | combination with zinc. Of course we now have politicized
           | medicine due to the fact Trump is taking it, and whatever
           | Trump does must be de-facto bad. Now we have countries
           | banning it's use, because of the WHO, who also said masks are
           | useless.
        
             | SketchySeaBeast wrote:
             | Given that the entire world is studying these drugs, and
             | many nations have now suspended their research, I don't
             | think you can chalk it up to a single person, unless you're
             | assuming the entire world is defining their own medical and
             | research policies based upon Twitter outrage.
        
             | kenjackson wrote:
             | Is there a peer reviewed study of this in a top journal?
             | Someone tried to send me a link from AAPS and I was like,
             | really...
        
         | ebg13 wrote:
         | Chemotherapy has been used as a cancer treatment for decades as
         | well. There is zero doubt that chemo is extremely harmful to
         | the body even as it destroys cancer cells. Sometimes you take
         | one thing that's unsafe because something else is more unsafe.
         | That doesn't make the thing safe.
        
         | kerkeslager wrote:
         | Hydroxychloroquine has always been unsafe. It's just that in
         | some situations, the risk of malaria is _more_ unsafe.
        
           | jki275 wrote:
           | it's taken by millions worldwide all the time, and not just
           | for Malaria.
           | 
           | It's "unsafe" in the same way that any medicine if misused is
           | unsafe -- but not more so than most others.
        
           | ping_pong wrote:
           | Wrong. Hydroxychloroquine is safer than acetaminophen.
           | Chloroquine has much higher side effects, but they different
           | drugs, in the same family.
        
             | kerkeslager wrote:
             | "Common side effects may include vomiting, headache,
             | changes in vision, and muscle weakness. Severe side effects
             | may include allergic reactions, vision problems, and heart
             | problems."
             | 
             | Sure, these side effects may be uncommon, but they're a
             | hell of a lot more common than they are if you don't take
             | hydroxychloroquine.
             | 
             | Incidentally, it's an open secret that a lot of the popular
             | NSAIDs wouldn't be OTC if they were discovered today.
             | Specifically because NSAIDs _aren 't_ just "safe", over the
             | counter dosages are quite low--low enough that they're
             | ineffective in many cases, which is why the same NSAIDs are
             | prescribed at orders of magnitude higher doses.
             | 
             | There's historical precedent for "safe" drugs being
             | problematic during a pandemic: aspirin poisoning was a
             | significant cause of death during the 1918 Spanish flu
             | epidemic.
        
               | ping_pong wrote:
               | Yes, so what you said didn't contradict anything I said.
               | Hydroxycloroquine is safer than acetaminophen which is
               | available openly at doses that can destroy the liver.
               | 
               | Here is what the CDC says about hydroxychloroquine. To
               | call it "unsafe" is ridiculous and spreading
               | misinformation.
               | 
               | Hydroxychloroquine is a relatively well tolerated
               | medicine. The most common adverse reactions reported are
               | stomach pain, nausea, vomiting, and headache. These side
               | effects can often be lessened by taking
               | hydroxychloroquine with food.Hydroxychloroquine may also
               | cause itching in some people.
               | 
               | All medicines may have some side effects. Minor side
               | effects such as nausea, occasional vomiting, or diarrhea
               | usually do not require stopping the antimalarial drug. If
               | you cannot tolerate your antimalarial drug, see your
               | health care provider; other antimalarial drugs are
               | available
        
               | kerkeslager wrote:
               | > Yes, so what you said didn't contradict anything I
               | said. Hydroxycloroquine is safer than acetaminophen which
               | is available openly at doses that can destroy the liver.
               | 
               | My point is, that even _if_ it 's safer than
               | acetaminophen (which is not in evidence) _that 's doesn't
               | mean it's safe_. Which is a direct contradiction to your
               | glib, "Wrong."
        
               | [deleted]
        
               | ping_pong wrote:
               | The CDC says "Hydroxychloroquine is a relatively well
               | tolerated medicine." So, unless you know something more
               | than the CDC, it sounds safe to me. That would absolutely
               | make what you're saying "wrong", and you're spreading
               | misinformation.
        
               | DanBC wrote:
               | CDC also said it shouldn't be used for covid unless it
               | was in a hospital, as part of a clinical trial. They said
               | this because it is dangerous.
               | 
               | Currently CDC refers to NIH for advice about using
               | Hydroxychloroquine:
               | 
               | https://www.cdc.gov/coronavirus/2019-ncov/hcp/therapeutic
               | -op...
               | 
               | https://www.covid19treatmentguidelines.nih.gov/whats-new/
               | 
               | > Chloroquine/Hydroxychloroquine:
               | 
               | > The Panel recommends against using high-dose
               | chloroquine (600 mg twice daily for 10 days) for the
               | treatment of COVID-19 (AI), because the high dose carries
               | a higher risk of toxicities than the lower dose.
               | 
               | > The FDA warning that cautioned against the use of
               | chloroquine or hydroxychloroquine for COVID-19 outside
               | the setting of a hospital or clinical trial was added to
               | this section.
               | 
               | Do they say this because it's a safe drug? No, they say
               | it because it kills more people than it helps when used
               | to treat covid-19.
        
             | jointpdf wrote:
             | Are you going to cite any actual evidence for that bold
             | claim? Here, like this:
             | 
             | > _We were unable to confirm a benefit of
             | hydroxychloroquine or chloroquine, when used alone or with
             | a macrolide, on in-hospital outcomes for COVID-19. Each of
             | these drug regimens was associated with decreased in-
             | hospital survival and an increased frequency of ventricular
             | arrhythmias when used for treatment of COVID-19._
             | 
             | https://www.thelancet.com/journals/lancet/article/PIIS0140-
             | 6...
        
               | jki275 wrote:
               | https://statmodeling.stat.columbia.edu/2020/05/25/this-
               | contr...
        
               | jakeogh wrote:
               | Among other issues, the authors of that study admit the
               | data is unavailable.
               | https://news.ycombinator.com/item?id=23305606
        
               | ping_pong wrote:
               | Evidence for what claim? That hydroxychloroquine is safer
               | than Tylenol?
               | 
               | I don't know why you connected what I said with anything
               | to do with COVID-19. I didn't say that it helped, in
               | fact, I think it was bad science that lead to that
               | belief. But the fact that hydroxychloroquine is safe is
               | beyond argument.
               | 
               | This is from the CDC:
               | 
               | Hydroxychloroquine is a relatively well tolerated
               | medicine. The most common adverse reactions reported are
               | stomach pain, nausea, vomiting, and headache. These side
               | effects can often be lessened by taking
               | hydroxychloroquine with food. Hydroxychloroquine may also
               | cause itching in some people.
               | 
               | All medicines may have some side effects. Minor side
               | effects such as nausea, occasional vomiting, or diarrhea
               | usually do not require stopping the antimalarial drug. If
               | you cannot tolerate your antimalarial drug, see your
               | health care provider; other antimalarial drugs are
               | available
        
               | kerkeslager wrote:
               | > I don't know why you connected what I said with
               | anything to do with COVID-19.
               | 
               | Well, I'm just gonna quote that so you can't change it.
        
               | jointpdf wrote:
               | I think replying with a sardonic "Wrong." and then making
               | an unsubstantiated claim made it pretty clear what the
               | pretext of your comment was. But sure...I'll give you the
               | benefit of the doubt.
               | 
               | Regardless, no it's not "safe beyond argument". Let's try
               | again.
               | 
               | FDA:
               | 
               | > _"Hydroxychloroquine and chloroquine:
               | 
               | - should be used for COVID-19 only when patients can be
               | appropriately monitored in the hospital as required by
               | the EUA or are enrolled in a clinical trial with
               | appropriate screening and monitoring. FDA is reviewing
               | the safety of their use when used outside of the setting
               | of hospitalized patients for whom use was authorized.
               | have not been shown to be safe and effective for treating
               | or preventing COVID-19. are being studied in clinical
               | trials for COVID-19, and FDA authorized their temporary
               | use during the COVID-19 pandemic under limited
               | circumstances through the EUA, and not through regular
               | FDA approval.
               | 
               | - being used under the EUA when supplied from the
               | Strategic National Stockpile, the national repository of
               | critical medical supplies to be used during public health
               | emergencies. can cause abnormal heart rhythms such as QT
               | interval prolongation can cause dangerously rapid heart
               | rate called ventricular tachycardia.
               | 
               | - pose risks that may increase when these medicines are
               | combined with other medicines known to prolong the QT
               | interval, including the antibiotic azithromycin, which is
               | also being used in some COVID-19 patients without FDA
               | approval for this condition.
               | 
               | - should be used with caution in Patients who also have
               | other health issues such as heart and kidney disease, who
               | are likely to be at increased risk of these heart
               | problems when receiving these medicines._"
               | 
               | >" _Be aware that hydroxychloroquine or chloroquine can:
               | 
               | - cause QT prolongation
               | 
               | - increase the risk of QT prolongation in patients with
               | renal insufficiency or failure
               | 
               | - increase insulin levels and insulin action causing
               | increased risk of severe hypoglycemia
               | 
               | - cause hemolysis in patients with Glucose-6-Phosphate
               | Dehydrogenase (G6PD) deficiency
               | 
               | - interact with other medicines that cause QT
               | prolongation even after discontinuing the medicines due
               | to their long half-lives of approximately 30-60 days_"
               | 
               | https://www.fda.gov/safety/medical-product-safety-
               | informatio...
        
               | ping_pong wrote:
               | Your reference conflates hydroxychloroquine and
               | chloroquine to try to prove your point. Chloroquiine is a
               | different drug with stronger side effects, which I
               | explicitly mentioned.
               | 
               | How about finding information about hydroxychlorquine on
               | its own? This is from the FDA itself:
               | 
               | https://www.accessdata.fda.gov/drugsatfda_docs/label/2007
               | /00...
               | 
               | I suggest you actually try to do some deeper research
               | besides just reading politicized versions of information.
               | First and foremost, educate yourself on the differences
               | between hydroxychloroquine and chloroquine, they are two
               | different chemicals. Just like how "dihydrogen monoxide"
               | and "hydrogen sulfate" are two different chemicals, even
               | though they have the word "hydrogen" in them.
        
               | jointpdf wrote:
               | Ah, so the sources that don't fit your narrative are
               | "politicized", yet others (from the same entity) are not?
               | What a convenient pattern of thought.
               | 
               | I read the document you linked to, and it outlines the
               | potential risks and side effects of the medication and
               | clearly specified that it should be administered with the
               | supervision of a doctor. This adds evidentiary weight
               | against your original claim that it is "safer than
               | acetaminophen" (which yes, is also dangerous if misused),
               | and you still haven't provided any evidence whatsoever
               | for that claim. I'll wait.
               | 
               | All drugs have risks and benefits. Some of those risks
               | can be magnified in nonlinear ways based on many
               | potential interactions, which is why people should rely
               | on medical advice from their doctors, and should fully
               | ignore opinions from _ping_pong_.
               | 
               | For some uses, the benefits outweigh the risks. Context
               | matters. Is grapefruit juice safe? It depends. In
               | combination with some medications, it can kill you.
        
       | cryptica wrote:
       | Mosquitoes are killing people by the hundreds of thousands! Let's
       | shut down the economy and do another round of corporate bailouts!
        
       | activatedgeek wrote:
       | It is uneasy to read this number and I don't get the full picture
       | here.
       | 
       | 1. What is the distribution of this number across geographical
       | regions? Is it uniformly spread across all regions? Are some
       | regions outliers?
       | 
       | 2. The distribution of this number over time of the year in every
       | geographic region is perhaps an interesting thing to look at for
       | short-term solutions.
        
       | ardy42 wrote:
       | Needs a (2017). This looks like the publish date:
       | 
       | > 18.08.2017
        
       | clairity wrote:
       | 700K per year. ok let's let the elephant out of the bag:
       | 
       | why haven't we been in lockdown every year until this deadly
       | scourge has been exterminated?
       | 
       | and no, it's not that the current pandemic was more uncertain.
       | even by january/february, it was clearly less contagious and
       | deadly than the 1918 flu. we had good bounds on potential
       | trajectory by early march, when many lockdowns were being
       | implemented.
        
         | root_axis wrote:
         | Your reasoning is flawed. Mosquito bites don't silently and
         | rapidly spread through human populations via close contact. If
         | I get bit by a mosquito and walk into a crowded bar the patrons
         | within are not at risk of becoming infected. Not true with
         | COVID.
        
         | 7leafer wrote:
         | "why haven't we been in lockdown every year until this deadly
         | scourge has been exterminated?"
         | 
         | One does not simply question the official corona narrative here
         | without being censored by downvoting or flagging.
         | 
         | But answering your question: that's because such scenario was
         | not developed and funded. Yet.
        
           | clairity wrote:
           | i'm happy to pay that (tiny) cost if it makes even one person
           | stop and question the narrative honestly for even a second.
        
             | 7leafer wrote:
             | So am I, my friend.
        
               | cryptoquick wrote:
               | Your pushback against the HN downvoter cowards,
               | especially when you've questioned the status quo and
               | planted a seed of dissent against the grain, is quite
               | appreciated by this particular HN user.
               | 
               | Honestly, I find the dialogue here toxic and coarse, and
               | I'm sure I'm a part of that, too. Ideally I'd just delete
               | my account, and never come back... But HN won't allow me
               | to delete my account, so, in spite, I'll keep coming
               | back.
        
               | fein wrote:
               | Years ago it wasn't like this, and I recall reading
               | mostly hardcore tech nerdery on here.
               | 
               | Now... I don't even know. HN and Reddit are pretty well
               | useless, and the only thing that keeps me around Reddit
               | are automotive and industrial/machining subs. Seems
               | strange that it was only 8 years ago.
               | 
               | Member when HN was overwhelmingly pro meritocracy? I
               | member.
               | 
               | I really miss reading King Terry's diatribes in showdead.
               | You'd probably be outright banned for that on here now.
               | 
               | I don't think people downvoted as much back then either.
        
               | 7leafer wrote:
               | The same thing happened to Russian IT hub, Habr.com.
               | Today it's nothing but a propaganda outlet aimed at those
               | who spin the cogs of this technocratic machine (and
               | especially at the suggestible teens who will spin them in
               | the future). The same thing over and over again all over
               | the internet and society as a whole. No choice, no
               | dissent, no free will. We know better. You get muted and
               | ridiculed. Silently. Efficiently. Yes you can but you
               | can't.
               | 
               | People today seem to be scared to death to think
               | different (not as in apple).
        
               | [deleted]
        
               | 7leafer wrote:
               | Please keep coming back and commenting, because otherwise
               | there's nothing to dampen this dittohead echo-chamber.
        
         | optimiz3 wrote:
         | > why haven't we been in lockdown every year until this deadly
         | scourge has been exterminated?
         | 
         | Probably because 700k/year is globally, while the US alone has
         | suffered 100k deaths in 3 months.
        
           | jakeogh wrote:
           | https://www.cdc.gov/nchs/data/health_policy/influenza-and-
           | pn...
        
           | clairity wrote:
           | currently ~350K global deaths for covid, in 6 months, since
           | december.
        
             | thawaway1837 wrote:
             | In about 3 months. For a disease that was growing
             | exponentially before action was taken and even now is only
             | just stopped growing in countries where action was taken.
             | 
             | And no mosquito outbreak has caused entire hospital systems
             | to collapse in various parts of the world.
        
         | throwaway894345 wrote:
         | I'm of the impression that in March and perhaps even in April
         | "experts" (whoever they are) thought the US alone could see
         | death tolls in the millions?
        
           | macintux wrote:
           | Without a lockdown, it's still possible. Latest estimates are
           | 0.5-1 percent fatality rate, which maps to 2-3 million people
           | here in the US, and if everyone got ill in a short
           | succession, because it is very contagious, the death toll
           | would certainly be higher.
           | 
           | Recent birthday party, 20 people, _every single one_ caught
           | the disease.
        
             | thawaway1837 wrote:
             | The 0.5-1% fatality rate would be a LOT higher if all those
             | people did fall sick at the same time.
             | 
             | Hospital systems would collapse because of the number of
             | sick people. Doctors and nurses would be missing because
             | they would almost all likely fall sick.
             | 
             | And people who would not die of COVID would die of other
             | stuff because healthcare systems would have collapsed.
             | 
             | This is what happened in Italy. This is what was happening
             | in NYC for a few days at its worst. This is what is about
             | to happen in Brazil and possibly in India.
        
             | throwaway894345 wrote:
             | > Latest estimates are 0.5-1 percent fatality rate
             | 
             | I read just a couple of days ago that the IFR (infection
             | fatality rate) is only ~0.25%-0.3%? Still ~four times
             | higher than that of the flu, but not ten times greater.
        
               | clairity wrote:
               | yes, IFR was trending toward 0.2-0.3% even in march, and
               | with time it's only become more likely that those are the
               | bounds. flu averages around 0.1% IFR, so likely 2-3X as
               | deadly.
        
               | saalweachter wrote:
               | The current CDC "best estimate" is ~0.4%, assuming an R0
               | of 2.5, with estimates of ~0.2% if the R0 is actual ~2 in
               | the US and ~1% if the R0 is actually 3.
        
               | throwaway894345 wrote:
               | Pretty sure that 0.4% is "among people who develop
               | symptoms" and 35% of infections are asymptomatic. So 0.4%
               | of 65% of infections, or ~0.26% of infections.
               | 
               | [0]:
               | https://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-
               | scena...
        
               | saalweachter wrote:
               | Thanks for the correction; everyone else, ignore what I
               | wrote one post up.
               | 
               | (It's a shame HN doesn't support strike-through; that is
               | my preferred way to retract a post without just deleting
               | it in shame.)
        
               | throwaway894345 wrote:
               | No problem. This stuff is all very nuanced and rapidly
               | changing. It's hard not to make a mistake.
        
           | clairity wrote:
           | it's not a single source, but certainly media editorialized
           | that into the collective consciousness as an attention-
           | capturing bonanza, and many politicians leapt onto the same
           | opportunity to promote their power, agendas and careers. same
           | for said "experts": a chance to be in the media, and if they
           | were wrong, oh well, that's science.
        
         | thawaway1837 wrote:
         | Umm, for one thing because going into lockdown wouldn't do
         | anything to prevent death by mosquito?
         | 
         | You do know that mosquitoes have wings and can move from place
         | to place without humans right?
        
           | clairity wrote:
           | you know that the most effective preventative for mosquito
           | bites are mosquito nets, like staying inside, with screens on
           | your windows and doors, right?
        
             | macintux wrote:
             | The lockdown isn't intended to protect the people staying
             | inside, although that certainly helps; it's designed to
             | protect everyone who they'd otherwise be infecting
             | unknowingly.
        
             | addicted44 wrote:
             | So you dont need a lockdown. You simply need mosquito nets.
             | 
             | So when you have a cheap solution that works, why would you
             | want to do something expensive that does not even work any
             | better than the cheap solution?
             | 
             | Other than making a nonsensical ideological statement, that
             | is.
        
             | tempestn wrote:
             | And people who live in areas where malaria is common do use
             | nets and screens as much as possible. Unlike many people in
             | western countries though, they don't have the luxury of
             | locking themselves down indefinitely. Nor do they have the
             | same expectation that the measures would only need to be
             | temporary.
        
               | smabie wrote:
               | > And people who live in areas where malaria is common do
               | use nets and screens as much as possible.
               | 
               | Ehh, not exactly. I used to live in Africa, parts where
               | there were tstsi flies and mosquitos. Despite being given
               | nets by the Gates foundation, people rarely used them.
               | Well, some used them as hair nets, others through them
               | away because their pastors convinced them their purpose
               | was to sterilize the African people, etc etc.
        
         | the_af wrote:
         | Where I live we're concurrently experiencing, besides COVID19,
         | a dengue fever outbreak. Dengue fever is spread by mosquitoes
         | -- specifically, Aedes Aegypti.
         | 
         | Dengue is way more serious than COVID19. Particularly
         | worrisome, having had dengue makes subsequent reinfections
         | _more_ life-threatening, not less.
         | 
         | There are ways to eradicate the mosquito -- mainly getting rid
         | of small clear water containers near/within your home, such as
         | vases and empty plant pots -- but we still don't do it until
         | it's too late and becomes a problem. A single neighbor who
         | doesn't do this endangers the whole block. And the authorities
         | don't give a fuck. It's infuriating, really.
         | 
         | So to rephrase your question, why don't we do something about
         | it? It's way more actionable than COVID19 (though lockdowns
         | don't work for the reasons others told you). So who knows?
        
           | clairity wrote:
           | yeah, that's the kind of thing that's absolutely infuriating
           | relative to the panic and paranoia we're seeing with this
           | pandemic just because it's novel.
        
           | acdha wrote:
           | > we still don't do it until it's too late and becomes a
           | problem. A single neighbor who doesn't do this endangers the
           | whole block. And the authorities don't give a fuck. It's
           | infuriating, really.
           | 
           | You seem to be strangely unaware of the large amount of money
           | which has been spent for decades on mosquito control by
           | individuals and all levels of government. There are
           | widespread control campaigns, active research into developing
           | new weapons (e.g. traps which are effective against tiger
           | mosquitoes), and community awareness to get more people
           | involved with habitat control and using things like bed nets.
           | 
           | I mean, does this sound like not doing something?
           | 
           | https://www.epa.gov/mosquitocontrol/success-mosquito-
           | control...
           | 
           | Several companies have been working for years on genetic
           | modifications to disrupt mosquito spread:
           | 
           | https://e360.yale.edu/features/genetically_modified_mosquito.
           | ..
        
             | the_af wrote:
             | > _You seem to be strangely unaware of the large amount of
             | money which has been spent for decades on mosquito control
             | by individuals and all levels of government._
             | 
             | Which government are you talking about? I don't live in the
             | US and you linked to EPA and Yale. I can tell you _my_
             | government is doing very little to combat dengue fever, and
             | when they do, it 's too little, too late.
             | 
             | > _widespread control campaigns [...] community awareness_
             | 
             | There's very little of that. And one careless neighbor
             | effectively endangers the whole apartment block.
        
       | JoeAltmaier wrote:
       | So, Covid is on track to beat this, sadly.
        
         | tempestn wrote:
         | Yes, but mosquitos kill that many every single year. Look at
         | the reaction to COVID-19 compared to the amount of effort going
         | into eliminating mosquito-borne disease. There's certainly
         | some, but it's far from the mobilization we see when a calamity
         | on this scale hits rich countries.
        
           | JoeAltmaier wrote:
           | Maybe that's cause-and-effect turned around? We stifled our
           | economy and mobilize a million researchers, because we can
           | afford to and have the will. It'll cost us in the end.
           | 
           | What do folks in malaria country do? Scavenge their
           | childrens' mosquito nets to catch fish etc. Reject modern
           | medicine and go to the local quack. Foul their water supplies
           | and poach their endangered species.
           | 
           | I know, we can have all the morals we can afford. But some
           | large-scale coordinated actions require a populace that is
           | educated and willing.
        
       | eruci wrote:
       | 1. Stupidity - More than the rest combined.
        
       | ahelwer wrote:
       | I grew up in Manitoba so have a _very healthy_ hatred of
       | mosquitoes - 50 of them once followed me into a car during the
       | <1s window of me opening & closing the door (I know because I
       | killed them all before driving) - but anyone leaning toward the
       | idea we should exterminate mosquitoes is incredibly reckless.
       | Ecological systems don't shift slowly, they collapse all at once.
       | Their continued existence is predicated on feedback loops of
       | mind-boggling complexity. To put it another way:
       | https://twitter.com/nntaleb/status/1120044775024013312
        
         | mantap wrote:
         | Citation needed. Mosquito extermination and habit destruction
         | has been going on in USA for 60 years at least. It is THE
         | primary method of malaria and dengue fever prevention around
         | the world and is supported by every public health body on
         | earth.
        
         | dmix wrote:
         | > anyone leaning toward the idea we should exterminate
         | mosquitoes
         | 
         | Is this actually a thing?
        
           | ahelwer wrote:
           | Of course it is, very popular among the Thought Leader
           | circuit: https://www.sciencealert.com/bill-melinda-gates-
           | funding-scie...
        
             | bamboozled wrote:
             | I love this, "Though Leader circuit", been looking for this
             | term for a while!
        
             | Mediterraneo10 wrote:
             | Malaria and dengue are only carried by certain mosquito
             | species. Suggestions to eliminate mosquitos through gene
             | therapy almost always concern those specific species, not
             | the relatively harmless (yet very annoying) mosquitos of
             | the global north.
        
             | graeme wrote:
             | Isn't that plan only to eliminate the specific species
             | responsible for disease carrying? There are many mosquitos,
             | the mosquito they're targeting is just one.
        
               | ahelwer wrote:
               | Intentions don't always match outcomes when it comes to
               | fiddling with these systems.
        
               | graeme wrote:
               | That's true. But, by what plausible mechanism could this
               | project switch from killing one species of mosquito to
               | killing all of them?
               | 
               | There's no way it would happen via natural selection. The
               | mosquito is engineered to die. The project has to keep
               | releasing new genetically engineered mosquitos to mate
               | with females.
               | 
               | I totally get the idea that removing all mosquitos would
               | likely lead to spiralling ecosystem collapse, and it's
               | possible that even killing this one species could do so.
               | 
               | But, are you arguing that trying to kill this one species
               | could kill all mosquito species? I just don't see how
               | that's possible with this mechanism.
        
               | jacobr1 wrote:
               | One idea: killing one specious could cause some kind of
               | "trophic cascade" style impact. Such as, imagine that
               | current preditor (B) of the targeted species (A) adapts
               | to target an alternate species (C) and is a more
               | efficient predator wiping them out. But then usual
               | preditor of (C) species (D) has now lost is food source
               | and dies off, as do species that depend upon it, maybe in
               | indirect ways, like its excrement is needed to fertilize
               | certain plant species and then other animals dependant
               | upon that plant are impacted and so on and so on.
               | 
               | Note: I think these types of scenarios are unlikely and
               | am in favor of the eradication programs (though I do
               | think we should have smaller-scale trials not just to
               | validate efficacy but also to understand unintended
               | impacts). But we have observed these types of impacts. It
               | isn't just a crazy idea. But nature also seems to me to
               | quite adaptable.
        
               | graeme wrote:
               | I think that's plausible, but you seem to have missed the
               | point.
               | 
               | OP asked whether anyone was considering killing all
               | mosquitos? Myself and others replied no, just this one
               | species.
               | 
               | It's indeed possible that there would be local ill
               | effects, possibly even on other mosquitos. But I don't
               | see how it would affect mosquitos outside Aedes Aegypti's
               | habitat.
               | 
               | Also, the species is invasive outside of Africa. This
               | increases the odds it could be safely eliminated in those
               | areas.
               | 
               | I still agree there's the possibility of great impacts.
               | But I don't think it could affect "all mosquitos".
        
           | epicureanideal wrote:
           | Yes, I am in favor of exterminating every last mosquito. I'd
           | rather deal with any results than the mosquitos themselves.
           | Also I had a long conversation with a specialist in a company
           | working on this and they convinced me that it wouldn't
           | actually be a big problem like some say.
        
             | seph-reed wrote:
             | Super down for this.
             | 
             | First test it on a small isolated island.
             | 
             | I think the main reason people don't like camping or nature
             | is because of mosquitos and biting ants. This dislike of
             | outdoors converts directly to a lack of environmentalism. I
             | don't know the conversion rate, so who knows how much more
             | we'd care for nature minus mosquitos, but if we're
             | destroying the planet either way, we should at least enjoy
             | some part of life without these parasites.
        
               | enchiridion wrote:
               | Let's take care of ticks whole we're at it!
        
             | nkozyra wrote:
             | > it wouldn't actually be a big problem like some say
             | 
             | Well this is the law of unintended consequences in action.
             | Many people don't _think_ it will have any negative effect
             | but we don 't know. Nature is extraordinarily complex and
             | disrupting it in such a huge way almost always carries
             | knock-on impact.
        
               | smabie wrote:
               | Saying we are too stupid to ever know anything is a
               | pretty anti-scientific attitude. Maybe global warming is
               | gonna make the world so much better, after all, we don't
               | really know anything. It's impossible to actually live
               | your life if you just throw your hands up and say "we
               | don't know".
               | 
               | What we do know is that mosquitos have killed more humans
               | than probably anything else _ever_. Shouldn 't that be
               | impetus enough to actually do something about it? Of
               | course, the problem is made worse by the fact that the
               | people who are advocating against doing anything aren't
               | the people that mosquitos are killing. If you knew a lot
               | of people who had died from Malaria, you might be singing
               | a different tune.
        
             | leeoniya wrote:
             | > Also I had a long conversation with a specialist in a
             | company working on this and they convinced me that it
             | wouldn't actually be a big problem like some say.
             | 
             | and a specialist working for an oil company convinced me
             | that climate change happens all the time. he wasn't
             | technically wrong, except that he wasn't around to enjoy
             | those other times to attest that it would be "no big deal".
        
           | yyyk wrote:
           | I am very much in favour. Well, not all mosquitoes, just
           | those carrying infectious diseases. Ok, maybe not even
           | wiping. We can keep some specimen in labs/zoos, and once the
           | parasites/diseases has been wiped out by killing the hosts,
           | we can release them again.
           | 
           | Humanity wipes out species by the dozens each year for no
           | reason and people shrug, but for some reason many people
           | don't want to target the few subspecies that are actually
           | extremely harmful to humans.
        
         | yyyk wrote:
         | The issue is very well studied - Mosquitoes are an invading
         | species in most areas; Only a few subspecies are harmful to
         | humans, and they'll be replaced by similar mosquitoes that
         | aren't.
         | 
         | Besides, there's a very wide gap between what the West is and
         | was willing to do when an infectious disease happens.
         | 
         | When Malaria hit the West, we drained entire swamps (and their
         | ecosystems) without a second though. When corona hits, we
         | justifiably lockdown entire countries. When Malaria hits poor
         | people, it's _think about the Mosquitoes_. I can 't help but
         | think there's a very ugly thing behind this double-standard.
        
           | 3pt14159 wrote:
           | Destroying every member of a specific species is ridiculous.
           | In the next couple decades we'll solve the majority of the
           | illnesses that these things cause and we can roll out the
           | cures around the world without the permanent damage to these
           | ecosystems.
           | 
           | I also lived for a time as a child in Manitoba and my
           | grandfather got live altering malaria, so I don't share any
           | love for these insects but we're part of something bigger and
           | just because the west drained entire swamps doesn't mean I
           | support that or that it validates making a species extinct on
           | purpose.
        
             | yyyk wrote:
             | "In the next couple decades", oh, a couple million would
             | die, until maybe we'll have something else (or not). You
             | have no right to make that choice.
             | 
             | The only reason people are even thinking about it, is
             | because it doesn't affect the West. That's callousness
             | masquerading as environmentalism. %$#@! the ecosystem* .
             | People are more important.
             | 
             | * Nevermind no one has even shown any way that anything
             | aside from the target would be harmed. Or that we could
             | reintroduce the species once the parasite is gone.
        
               | throwanem wrote:
               | > %$#@! the ecosystem* . People are more important.
               | 
               | You do know humans _need_ a functioning ecology in order
               | to survive, right?
        
               | JoeAltmaier wrote:
               | ...and you read the part about mosquitoes being invasive
               | species, right? So removing them improves almost every
               | ecosystem they're found in.
        
               | throwanem wrote:
               | You read the part about it being a specific couple of
               | species, right? So unless somebody comes up with a
               | brilliant plan that targets specifically those species,
               | _and_ only in the parts of the world where they 're not
               | native, _and nothing else_ , we're still risking the same
               | kind of consequences as with DDT, or neonicotinoids. The
               | kind we can't predict in advance are going to fuck us
               | over.
               | 
               | I mean, don't get me wrong, I love the optimism inherent
               | in a perspective on the world that says there's
               | necessarily a technological solution to everything, and
               | more than that, one that modern-day humans are certainly
               | smart enough to find. I just wish it didn't so lend
               | itself to hubris.
        
               | jacobr1 wrote:
               | The one plan we do have that targets a specific species
               | is the spread of neutered males. We've done this
               | successfully in the past with screw-worm.
        
               | throwanem wrote:
               | The sterile-insect technique does work, but it's not
               | going to achieve the kind of eradication people in here
               | are talking about. Wild-eyed ideas about mass pesticide
               | application and CRISPR gene drives are more the sort of
               | thing that actually concern me, or would if I thought
               | anyone talking about them was anywhere near the required
               | levers of power to actually make them happen. As it is, I
               | just wish people had enough sense of history to
               | understand the import, although I suppose in the age of
               | alternative facts that's far more than can reasonably be
               | expected.
        
               | yyyk wrote:
               | Strile-insect achieves 90-95% (e.g.[1]). Sustained and
               | combined with a bit from the other approaches (netting,
               | drying some swamps, this article suggests a medicine to
               | make infected biting mosquitoes die, etc.), we can at
               | least repeat what happened in much of the West - the
               | population was reduced so much the parasite went extinct,
               | when the population bounced back it was 'clean' (in other
               | places in the West these mosquito simply went extinct).
               | 
               | [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489809/
        
               | throwanem wrote:
               | Well, hell, OK, then, let's do that.
        
               | yyyk wrote:
               | We're talking about a very very specific ecosystem, which
               | is frankly not relevant to humans (we can do fine without
               | swamps).
               | 
               | There's no balance between the concern we don't have for
               | the many ecologically damaging things humans do for
               | profit and the nagging when we think about intervening
               | with a disease that killed millions.
        
             | jki275 wrote:
             | That's a nice theory, and I hope it happens, but hope is
             | never a course of action, especially when we're talking
             | about total hypothetical with no basis in fact at all.
        
           | ahelwer wrote:
           | Nature doesn't care about how something looks politically.
           | Those decisions were bad and aren't vindicated because
           | nothing went wrong (there are other cases where things went
           | very very wrong, as another commenter mentions with DDT). In
           | a nonlinear world you can never know whether you were right
           | or just lucky.
        
             | yyyk wrote:
             | Make no mistake, the West would do DDT all over again if
             | that was the price for getting rid of Malaria. But a very
             | targeted intervention is off limits due to 'well, we don't
             | know, _something_ might go wrong '.
             | 
             | Nature doesn't care if humans all die. Nature doesn't
             | 'care' at all. Humanity does. And this looks very ugly and
             | very hypocritical.
        
               | throwanem wrote:
               | "The West" _is_ doing DDT all over again. This time it 's
               | neonicotinoids, and just like with DDT, they're being
               | pushed by ag conglomerates as a way to increase profits,
               | with a side of "cigarettes give you healthy skin!" style
               | propaganda to make them look innocent.
               | 
               | Last time, we "merely" almost wiped out a whole class of
               | apex predators and caused a collection of trophic
               | cascades. This time, with a menu of unintended
               | consequences only the most obvious of which is the
               | "colony collapse disorder" that's been imperiling
               | pollinators worldwide, we might just end up managing to
               | break modern agriculture entirely and cause famines
               | worldwide, too.
               | 
               | So, yeah, "targeted interventions" merit extreme
               | skepticism, because we as a species _suck_ at them. If
               | you want to look at that through a lens of anti-
               | Westernism, you 're welcome.
        
               | yyyk wrote:
               | There's already a "colony collapse disorder", and nobody
               | does anything. But when it comes to the Third World,
               | suddenly we have to do nothing because something _might_
               | happen (nobody even has a mechanism. We 're supposed to
               | sacrifice millions for delusions). This is unacceptable.
               | Fortunately, there are enough good people in the world to
               | ignore the callous.
        
               | throwanem wrote:
               | The point you're ignoring in your haste to indict
               | everyone you don't like - due to what I suspect to be
               | your complete ignorance of, or at least disinterest in,
               | the millions of dollars annually spent on research aimed
               | at eradicating malaria worldwide by the very same "West"
               | for which you cannot find enough opprobrium - is that we
               | _can 't know_ what consequences will come of these kinds
               | of broad, blunt methods.
               | 
               | Nobody _expected_ DDT to drive large birds of prey nearly
               | to extinction. Nobody _expected_ neonicotinoids to
               | concentrate in ecosystems and have a very similar effect
               | on the insects we depend on to pollinate our food crops.
               | It 's not about predicting that terrible things will
               | happen. It's that we aren't able to make sure terrible
               | things _won 't_. Neonicotinoids already have us at non-
               | negligible risk of worldwide famine through agricultural
               | collapse as a result of consequences we were too stupid
               | and too hubristic to predict. How many millions do you
               | think that will kill if it happens?
               | 
               | Because that's the kind of risk you're proposing - and,
               | just as with that famine, it's a risk that will hit worst
               | on the most vulnerable, least privileged people in the
               | world. You know? The same ones in whose supposed defense
               | you're making such a performative display of contempt?
        
               | jacobr1 wrote:
               | I think the risk equation being questioned is different.
               | Today, right now, with a better understanding of the
               | risks for DDT, would it be better to have a campaign to
               | eradicate malaria in sub-saharan Africa with tools like
               | DDT? There would be ecological damage, both anticipatable
               | and unknown. And that would have second and third-order
               | detrimental impacts. But we'd also have a huge gain.
               | Would it be worth it? Right now it is hard to have that
               | kind of discussion.
               | 
               | Another related example: is it better to have the
               | consequences of polluted cities powered with unclean
               | coal, than to have a less developed country with fewer
               | resources to spend on things like healthcare. Which on
               | net is better? I certainly don't know, but the tradeoffs
               | are real.
        
               | yyyk wrote:
               | I'm not indicting the entire West. I'm indicting certain
               | people in the West that post silly almost conspiracy
               | style stuff against obvious solutions to a deadly
               | disease. There's an obvious balance here, and it's not on
               | the 'we don't know how but _something_ might happen '
               | side. How about we all stop posting on HN? After all,
               | posting _might_ change magnetic fields which _might_
               | change a butterfly 's path which _could_ cause a deadly
               | hurricane?
               | 
               | P.S. We knew even at the time DDT was poisonous to life,
               | and that draining swamps kills ecosystems. What changed
               | wasn't so much our knowledge, but the situation (the West
               | had gotten rid of many deadly diseases by that time,
               | mosquitoes had started to develop resistance).
        
               | throwanem wrote:
               | Well, you're making not posting on HN any more look like
               | an appealing option, I'll give you that much.
        
               | jschwartzi wrote:
               | I find your appeal to hyperbole pretty distasteful.
               | Please be civil and argue from the facts of the
               | situation. There's a huge chasm of difference between
               | what GP is saying and the words you're putting in their
               | mouth.
        
               | yyyk wrote:
               | What am I missing?
               | 
               | The current situation is that many people needlessly die.
               | The current approaches don't work well enough. Various
               | radical approaches to fixing that have been investigated
               | and tested to a significant degree. Now given the cost,
               | testing and various answers to the objections, there
               | comes the time the objections have to put a bit more meat
               | and go beyond _people have screwed up before_ , and
               | _something_ might happen.
        
               | jki275 wrote:
               | Just for the record, DDT didn't actually do any of that,
               | and your histrionics about pesticides aren't supported by
               | evidence either.
               | 
               | The West murdered millions of third world children when
               | we banned DDT.
        
               | throwanem wrote:
               | A series of extraordinary claims, for which you don't
               | care to provide any support whatsoever. Okay.
               | 
               | I did, with a little effort, find a single source [1] for
               | your "DDT didn't harm birds" claim. Of course, he's [2]
               | also a climate denier, a conspiracy theorist, and a
               | lobbyist for companies whose financial interests are
               | coincidentally in total alignment with his "scientific"
               | advocacy. But hey, if that's the company you want to
               | keep, don't let me dissuade you.
               | 
               | [1] http://archive.is/UTyoT#selection-2159.0-2156.3
               | 
               | [2] https://en.wikipedia.org/wiki/Steven_Milloy
        
               | jki275 wrote:
               | You didn't look very hard:
               | 
               | https://www.thenewatlantis.com/publications/the-truth-
               | about-...
        
               | throwanem wrote:
               | Zubrin's fine, if excessively Golden Age of Science
               | Fiction for my taste, when he talks about Mars. Earth,
               | not so much. But, again, if you want to keep company with
               | someone who's super excited about anthropogenic climate
               | change, likens mosquitoes to Nazi V-2s, and alludes with
               | crafty dissimulation to the conspiracy theory around
               | environmentalism that forms the backbone of such sober
               | documentaries as "Kingsman: The Secret Service" (2014),
               | go for it.
        
               | Gibbon1 wrote:
               | The US stamped out malaria in the 1930's as a public
               | works program. That was before DDT.
        
         | gjs278 wrote:
         | if we kill the mosquitoes we'll be fine.
        
         | [deleted]
        
         | petters wrote:
         | The ecological systems would likely be fine; the mosquitoes
         | responsible for diseases are a minority.
         | 
         | But that is beside the point and does not matter. What matters
         | are 700,000 human lives annually.
         | 
         | It's tragic really. If we had these diseases in Europe or North
         | America, we would have already done this.
        
           | ahelwer wrote:
           | Maybe you didn't click the link, so I guess I'll ask you: how
           | many humans would die if we _did_ exterminate the mosquitoes?
           | More or less than 700,000? Do you know? You have no way of
           | knowing how ecological systems would react.
        
             | lucisferre wrote:
             | Several of the comments responding to him do address this
             | and at least some of the people commenting do appear to
             | know, or at least know more than Nassim Taleb appears to.
             | 
             | Besides, his statement isn't an argument, and present no
             | facts or information.
             | 
             | > Imbecilic remark. Do you know how many humans would die
             | if we eliminated mosquitos? Any idea?
             | 
             | petters also appears to be correct on what would happen if
             | we had these issues in North America. Your own province
             | kills mosquitos en masse and those ones aren't even
             | carrying deadly disease they are just a nuisance.
             | 
             | https://www.cbc.ca/news/canada/manitoba/deltamethrin-
             | first-u...
        
               | ahelwer wrote:
               | Taleb's position in general is one of extreme
               | conservatism when meddling with ecological systems (for
               | example he is also against GMOs). The basis for this
               | conservatism is his general concern with risk in a
               | nonlinear world. He does indeed put forth an argument,
               | which is: can you predict the effects of this? No, you
               | cannot, and possible effects include ecological collapse.
               | 
               | Re: Manitoba, spraying to reduce mosquito populations in
               | urban areas is a whole different ball game from
               | extermination.
        
               | yyyk wrote:
               | Taleb's position in a nutshell:
               | 
               | http://dresdencodak.com/2009/09/22/caveman-science-
               | fiction/
        
           | pitaj wrote:
           | We did already do that. It was called spraying DDT
           | everywhere.
        
         | wvenable wrote:
         | Not all mosquito species feed on humans. If we eliminate just
         | those, there will still be thousands of other mosquito species
         | in the environment.
        
         | condesising wrote:
         | The mosquitoes provide any benefit? Reading this article is
         | scary, I figured Science would just go for Total eradication.
        
       | condesising wrote:
       | IIRC Weren't they genetically modified mosquitoes to stop their
       | spread? I guess I'm curious at what point would the Chi turn and
       | we would gain control over the mosquito population?
        
       | paulorlando wrote:
       | This is a look into mosquito extirpation programs and what
       | happens when they go wrong: https://unintendedconsequenc.es/more-
       | on-mosquitoes-new-data/
        
       | dean wrote:
       | According to the book "The Mosquito: A Human History of Our
       | Deadliest Predator" by Timothy C. Winegard, the mosquito has
       | killed an estimated 52 billion people from a total of 108 billion
       | people that have ever lived. (Not sure how those numbers were
       | determined.)
        
         | gxqoz wrote:
         | This book is in a genre I like (microhistories) but I found it
         | pretty dull reading. It's basically a very superficial history
         | of "the world" (mainly Western Europe) that posits malaria to
         | be the cause of pretty much every world event. I'm sure there's
         | some truth to this, but the plodding military metaphors and
         | oversimplifications really started to wear on me.
         | 
         | I haven't read it, but a recent review (https://lrb.co.uk/the-
         | paper/v42/n11/steven-shapin/drain-the-..., possibly behind a
         | paywall) suggested Sonia Shah's The Fever to be a better book
         | on the topic.
        
       | mac01021 wrote:
       | Just as a curiosity, humans kill hundreds of trillions of insects
       | annually.
       | 
       | [1] https://www.quora.com/How-many-insects-die-from-people-
       | stepp...
        
         | dheera wrote:
         | Insects, however, reproduce so much that without population
         | control, the ecosystem would be in imbalance very quickly, and
         | they can't be educated to have less children. Insects were
         | "designed" into the system such that a large number of them are
         | expected to die.
         | 
         | I wouldn't be surprised if birds and spiders kill far more
         | insects than people.
        
           | mac01021 wrote:
           | They probably do if you count only humans directly squashing
           | the insects with their hands/feet/cars.
           | 
           | If you count things like pollution, pesticides, land use,
           | they absolutely don't.
           | 
           | Insect populations have been reduced to a fraction of their
           | former size over the last few decades due to human activity.
        
       | xenocyon wrote:
       | This is a strangely worded title: why not say "mosquitoes"
       | instead of "tiny insects" since that is what is being referred
       | to?
       | 
       | Insects as a whole are of crucial planetary importance.
        
         | gregd wrote:
         | Sorry. When I cut/paste the subtitle of the article on
         | submission, I thought I grabbed the entire subtext. Not sure
         | how that happened, but I've edited the title.
        
         | creaghpatr wrote:
         | Agree, the HN header should be updated. No other insects
         | mentioned.
        
           | gregd wrote:
           | I updated it and apologized for the error.
        
         | throwanem wrote:
         | If we really want to be accurate, why not talk about the
         | parasites actually to blame, which the mosquitoes incidentally
         | transmit? I carry no brief for the little flying bloodsuckers,
         | but I also don't want to find out what happens to ecosystems
         | when the many animals that prey on mosquitoes and their larvae
         | are suddenly deprived of them.
        
         | leeoniya wrote:
         | > This is a strangely worded title
         | 
         | clickbait
        
       | yboris wrote:
       | If you want to reduce the number, consider donating money to the
       | _cost-effective_ Against Malaria Foundation
       | 
       | https://www.givewell.org/charities/amf - review by GiveWell, and
       | independent charity evaluator
       | 
       | $2 donation results in 1 net that lasts 3-4 years protecting 1.8
       | people on average from malaria $3
        
       | jonshariat wrote:
       | This is why Verily's https://debug.com/ project is so
       | interesting.
       | 
       | The idea is to create modified mosquitoes that can't bite or
       | breed and release them to "breed" with the general populous thus
       | neutralizing them.
        
         | jschwartzi wrote:
         | Another way we can control mosquitoes is by making sure the
         | native bird populations are healthy. Where I live tree and bank
         | swallows eat tons and tons of mosquitoes and other bugs every
         | year which helps control the population. I wouldn't recommend
         | releasing these birds elsewhere because they may not have any
         | natural predators but surely where there are tons of mosquitoes
         | there are also predators of mosquitoes as well.
         | 
         | Otherwise this reminds me of well-meaning efforts to control
         | erosion by planting Kudzu or Himalayan Blackberry everywhere.
         | Ultimately they just become an invasive species. And I could
         | also see eradicating mosquitoes as removing a food species for
         | many other animals. This is a really bad idea.
        
           | throwaway894345 wrote:
           | Is this true? I recall looking into this and finding that
           | swallows, bats, and other "mosquito predators" don't put a
           | dent in mosquito populations (mosquitoes are numerous and
           | only account for a negligible percentage of these predators'
           | diets).
        
         | baybal2 wrote:
         | Malaria can be eradicated by timely treatment, and quarantine.
         | There are countries that defeated malaria with nothing more
         | than that.
        
         | dubcanada wrote:
         | What's to say something strange doesn't happen with these
         | "modified mosquitoes" and we somehow engineer a super mosquitos
         | or kill off 4 other species accidentally.
         | 
         | I really want to believe that doing this would be something
         | that humans should explore, but I think the chance of something
         | going wrong is fairly high. Considering our rather terrible
         | track record with stuff like this (weapons, pesticides, etc).
         | 
         | It often takes decades to truly see how it works, so while we
         | may end the mosquitos problem we may make ourselves a worse
         | one.
        
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