[HN Gopher] All-you-can-eat study shows body copes well with one...
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       All-you-can-eat study shows body copes well with one-off calorie
       indulgence
        
       Author : woldemariam
       Score  : 41 points
       Date   : 2020-07-28 22:07 UTC (52 minutes ago)
        
 (HTM) web link (www.bath.ac.uk)
 (TXT) w3m dump (www.bath.ac.uk)
        
       | mrfusion wrote:
       | It seems like this would be obvious. Why would one instance of
       | overeating damage your metabolism?
        
       | sbierwagen wrote:
       | N = 14
       | 
       | https://www.cambridge.org/core/journals/british-journal-of-n...
        
       | hprotagonist wrote:
       | It shouldn't be terribly surprising that we do OK with "feast and
       | famine", especially if you're young. I remember being 16 and
       | eating an entire large NY pizza for an afternoon snack before
       | dinner...
       | 
       | I assert without proof that it's the all-feast-all-the-time
       | dietary novelty for most of humanity in the last, oh, 200 years
       | that probably throws a spanner in the works.
        
         | centimeter wrote:
         | Another complication is that most of our ancestors would
         | probably only have been "feasting" on meat - there wouldn't
         | have been any bread, sugar, palm oil, etc. in the mix.
        
           | hprotagonist wrote:
           | that's at best a very contentious claim. Midden heaps tend to
           | preserve bones longer than carrot-tops, though, which
           | certainly skews the record.
           | 
           | Certainly the vast majority of humanity throughout _written_
           | history has subsisted primarily on non-meat foods, be they
           | wheat, barley, maize, or whatever. Peasants were not
           | regularly eating meat; often we have the written record to
           | point to for that, as well as archaeological evidence from
           | grave finds and the like.
           | 
           | and my usual critique of "paleo" holds here, which is that it
           | ignores evolution. As a species, we've evolved the
           | persistence of digesting lactose at least twice, in
           | independent subgroups, through two different metabolic
           | pathways, so it's not like we're incapable of getting used to
           | dietary shifts over the span of human history.
        
           | AlotOfReading wrote:
           | I'm not sure that's correct. Honey and fruit feasts are both
           | quite common among extant forager groups in Africa. I don't
           | see why our ancestors wouldn't have made use of the same
           | resources.
        
       | notJim wrote:
       | > Hormones that are released by the gut to stimulate insulin
       | secretion and increase feelings of fullness were changed the most
       | by overeating (e.g. GLP-1 and peptide YY).
       | 
       | I wonder if people who chronically overeat (hello!) develop
       | insensitivity to these hormones, leading to a cycle where it
       | becomes harder to eat the correct amount. Similarly, I wonder if
       | people who tend to eat too little are hyper-sensitive to them,
       | making it hard to gain weight.
        
         | pier25 wrote:
         | I once worked with a biochemist that works on diets and he told
         | me that the body "forgets" how to process carbs after a couple
         | of days. If you only indulge in carbs once a week it won't be
         | able to process it, much like the cheat day thing from Tim
         | Ferris.
         | 
         | I don't remember the exact technical mechanism he described and
         | quite frankly I don't know if it's true... but there you go.
        
           | mrfusion wrote:
           | Interesting idea. Tim is fine with slow carbs though like
           | legumes.
        
         | leetrout wrote:
         | I think it's a lot of what Tim Ferris talks about in 4 Hour
         | Body.
        
       | opportune wrote:
       | Is this really that interesting? Overeating doesn't appear to
       | affect blood sugar beyond regular eating in healthy adults -
       | seems normal to me. Lipids didn't spike after a single meal -
       | also seems normal. All they found is that these are linear up to
       | the point of satiety and then the body's hormones keep levels in
       | check beyond that.
        
         | notJim wrote:
         | Why this anti-intellectualism? Are studies only worth doing or
         | reading if you personally find the results surprising? If we
         | don't have data about something, we should get it, rather than
         | just assuming our intuitions are correct.
        
           | opportune wrote:
           | I'm not being, or at least intending to be, anti-
           | intellectual. I do think that a study confirming something
           | this obvious is not notable or interesting enough to be at
           | the top of HN though
        
             | enjeyw wrote:
             | I personally agree that you're not being anti-intellectual,
             | and that your original question was valid.
             | 
             | That said, I think there's huge value in studies that
             | scientifically validate things we believe to be true to
             | 'common knowledge' (because often common knowledge is
             | totally wrong), which justifies this study being at the top
             | of HN.
        
               | ska wrote:
               | Considering how little we actually understand
               | scientifically about these processes, nearly any good
               | study (not a judgement on this paper) would seem to be
               | worth doing.
        
           | jldugger wrote:
           | I guess it's the difference between science and news. We can
           | do all kinds of confirm common belief science, but maybe it's
           | not worth the HN thread when common beliefs are upheld?
        
       | rozab wrote:
       | This makes sense to me since early humans hunted large game.
       | Also, feasting seems to be present in some form in almost all
       | human cultures. If it really were harmful, I would expect some
       | cultures to have figured that out.
        
       | benatkin wrote:
       | Add Brazilian Steakhouses to the list of anecdotes.
        
         | rootusrootus wrote:
         | I really love going to Fogo de Chao, but it's hard not to
         | overindulge. The worst I've ever felt in my life was after a
         | trip to Fogo. An hour later I was still just sitting up
         | straight on my couch trying not to look as uncomfortable as I
         | felt. Took a while before I went back again, and I had a lot
         | more control.
        
       | carrolldunham wrote:
       | > Four hours after eating maximally, the participants [...]
       | reported no desire to eat anything else, including sweet foods.
       | This was surprising because reward centres in the brain are
       | usually food specific, so eating pizza might not be expected to
       | change the desire for sweet food.
       | 
       | No it's not surprising because - whether it's contrary or not the
       | neurodrivel "reward centres in the brain" i'm not sure - as an
       | adult you know that craving for a specific food item is entirely
       | a high-level construction in your psychology to do with the story
       | you're telling yourself about what it will mean to eat that, etc.
       | and you should have experienced that it will go away as soon as
       | you eat enough of anything else.
        
       | curiousllama wrote:
       | > Young men can eat twice as much food as they need to feel
       | 'full', research shows.
       | 
       | I. AM. SHOCKED.
        
       | yboris wrote:
       | "The researchers acknowledge that their study involved healthy
       | young men, so they plan to investigate whether similar effects
       | are apparent in women, and for overweight and older populations."
        
       | ed25519FUUU wrote:
       | This was a big thing with Tim Ferris when he was making an
       | argument for "cheat days". Personally, I also found cheat days to
       | be effective when on a restrictive diet. I think he ended up
       | actually weighing his poop to prove the point.
       | 
       | I did notice that I couldn't breakthrough some key weight loss
       | levels without both cheat days and intermittent fasting, with the
       | cheat days seeming counter-intuitive to me.
        
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