[HN Gopher] Old Dogs, New Research and the Secrets of Aging
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Old Dogs, New Research and the Secrets of Aging
Author : gmays
Score : 53 points
Date : 2020-11-13 15:17 UTC (7 hours ago)
(HTM) web link (www.nytimes.com)
(TXT) w3m dump (www.nytimes.com)
| asdf333 wrote:
| I've noticed more health and aging related articles on this site.
| I wonder if its a sign the HN community is getting older. :)
| perardi wrote:
| Could be that "pandemic" thing making people a bit more
| cognizant of mortality.
| throwaway201103 wrote:
| The people dying of COVID are for the most part over age 70.
| Many are over 80. This is an age where death and disease are
| unremarkable.
| jjulius wrote:
| That's not necessarily what OP's saying. My inference is
| that OP is suggesting that a constantly prevalent pandemic
| makes people more likely to think about their own health
| and mortality in a broader sense than they might if there
| weren't a pandemic.
| flavor8 wrote:
| > for the most part over age 70.
|
| CDC categories don't line up to "70" that well, but there
| are plenty of younger deaths.
|
| 51% are 74 or younger.
|
| 33% are 64 or younger.
|
| https://data.cdc.gov/NCHS/Provisional-COVID-19-Death-
| Counts-...
| belval wrote:
| I think you should check the very link you sent because
| only 21% are 64 or younger. The ranges overlap.
| jolmg wrote:
| These articles have been getting popular since before the
| pandemic.
| [deleted]
| melling wrote:
| The site is almost 15 years old so it's possible.
|
| People become a little more self-aware as they get older.
|
| First you know someone famous that died young from a horrible
| disease.
|
| Next you personally know someone who died from a disease.
|
| Then you get older and wonder if the "1 in 3 people" might be
| you.
| drran wrote:
| I take anti-aging drugs for about 10 years. I heard about
| them at HN.
| pmiller2 wrote:
| How has that worked out for you? What are you taking?
| api wrote:
| What's in your stack bruh?
| reducesuffering wrote:
| Betting this is berberine or metformin?
| ve55 wrote:
| I think a lot of it is that we're just now starting to get to
| where we need to be as a civilization for anti-aging to start
| to become something that not only sounds feasible, but is
| feasible. I've noticed interest steadily increasing over the
| last 5 or so years, and think this will be a huge topic in the
| next few decades.
| grishka wrote:
| The aging-related research has been going for quite some
| time, so it's not surprising it's starting to bear fruit, for
| now in the form of better understanding of the underlying
| mechanisms. The consensus seems to be shifting from "wear-
| and-tear model" to a series pre-programmed epigenetic
| alterations, which, to me at least as a layman, feels more
| plausible. There's a good chance we'll see some anti-aging
| treatments released within our lifetimes. We might end up
| being the first generation to have reached the longevity
| escape velocity.
|
| The reason it's only starting to emerge now is as far as I
| understand that molecular biology is a relatively new field,
| and the related technologies simply didn't exist not so long
| ago.
| rostifar wrote:
| It's odd that this article doesn't mentioned Celevity, which is
| definitely one of the big players in this field.
| slacka wrote:
| From my grandparent to me, there has always been German Shepherds
| in our family. Starting the 80's all of our dogs started dying
| much earlier, ~6-7 of cancer. In the early 2000's, we switched to
| raw diet from premium store bought kibble to raw. Sure enough,
| not only did their coat improve not a single cancer death under
| age of 13. I know it's anecdotal, but in my dog world circle and
| family, we've all observed similar results.
|
| It's a cruel that our best friends and most loyal companions live
| such short lives as it is. Giving them top nutrition is a small
| price for the added years.
|
| As to how this applies to humans? If you want to live a long and
| healthy life: avoid processed foods.
| rantwasp wrote:
| aging (and anti-aging medication) has the potential to become the
| next big thing.
|
| My dog is part if the DogAgingProject and it's really exciting to
| see some focus on something that impacts all of us.
| season2episode3 wrote:
| I have such mixed feelings about this.
|
| It's not a great movie but this really does remind me of
| Elysium, in that we're truly heading for a world where those
| with means can live indefinitely. And those without means...
| asdfman123 wrote:
| The best thing I learned from this article: to calculate a dog's
| human age, you don't multiply their age times 7 (7x). You use the
| following formula:
|
| ln(x)*16+31
|
| It makes sense, because a 1-year-old dog definitely seems much
| more grown up than a 7 year old kid.
| antisthenes wrote:
| Umm...doesn't the formula imply that the dog age starts at 31?
|
| That makes no sense either. My 1 year old dog is definitely not
| a 31 year old adult as far as behavior goes (incidentally, I am
| myself ~31,).
|
| I'd put 1 year approximately equivalent to a teenager,
| depending on the size of the breed (12 year old for larger
| breeds, late teens for small breeds)
| Ancalagon wrote:
| Anecdotally I'm assuming this equation must be breed-specific
| because I've had a number of dogs 8+ years old that did not
| appear to act or look very senior.
| duskwuff wrote:
| Playing around with the numbers a bit, I think it's pretty
| seriously wrong.
|
| A 6-month old dog is still a child, in dog terms. This
| formula says they're nearly 20 years old; I'd be inclined to
| say that the "right" answer is more like 15 years, if not
| less.
|
| A 1-year old dog is beyond adolescence but is still maturing,
| but this formula says they're 31 years old, well into
| adulthood.
|
| A 5-year old dog is in the prime of their life; this formula
| says they're 56 years old, well into the range of what we'd
| consider a senior.
|
| A 30-year old dog would set a new world record. (The oldest
| dog known was about 29.5 years old.) This formula maps that
| to 85 years, which is old, but not extraordinarily so.
| asdfman123 wrote:
| I think it has to be because I've heard small dogs age more
| slowly. Maybe there's a way to adjust for weight/breed that I
| could find if I were willing to dig through the original
| research paper.
| Legion wrote:
| Right? My yellow labrador is pushing 11 and he's all but
| indistinguishable from his 2-year-old self, aside from a
| relatively minor decline in energy.
|
| We call him the Eternal Puppy. We expected aging was going to
| catch up by now. Still very little sign that it's happening.
|
| If I had that dog's energy, I would never be out of shape.
| jonas21 wrote:
| It's unfortunate that the chart in the NYT article shows the
| incorrect Labrador:Tom Hanks mapping. The figure from the paper
| with the correct mapping is here:
|
| https://marlin-prod.literatumonline.com/cms/attachment/f65cb...
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