[HN Gopher] Scientists tracked down a mass killer of salmon
       ___________________________________________________________________
        
       Scientists tracked down a mass killer of salmon
        
       Author : prostoalex
       Score  : 301 points
       Date   : 2020-12-15 16:10 UTC (1 days ago)
        
 (HTM) web link (www.nytimes.com)
 (TXT) w3m dump (www.nytimes.com)
        
       | chefkoch wrote:
       | It would be interesting why this hasn't been observerd at other
       | places. I guess there are many places where road dirt is swept
       | Info rivers.
        
         | WhoIsSatoshi wrote:
         | I'd theorize it has, but nobody has been able to coordinate
         | such a focused investigation.
        
         | 238475235243 wrote:
         | It rains a lot there, not in other places.
        
           | shellfishgene wrote:
           | The paper also has data for Los Angeles, with concentrations
           | begin similar.
        
         | shellfishgene wrote:
         | It's surprising they did not check toxicity on other salmon
         | species. Either it's specific to the coho salmon, which is
         | maybe unlikely, or other salmon species are not stocked in
         | streams near cities?
        
           | jandrese wrote:
           | Fish in general have been undergoing a mass extinction event
           | in recent decades. We normally blame it on overfishing, but
           | effects like this could have been right under nose the entire
           | time and simply missed because nobody was looking for it.
        
           | mattbk1 wrote:
           | They have to start somewhere. I'm sure we'll see more papers
           | in the future.
        
         | blue_cadet_3 wrote:
         | The salmon swim up Cedar River in Renton, WA which a heavily
         | used road follows and crosses the river few times. That gives
         | plenty of opportunity for runoff to get into the river.
        
           | Tagbert wrote:
           | BTW - the Cedar River also flows past Renton Airport which
           | serves small aircraft which use aviation gasoline. That fuel
           | is still allowed to contain tetra-ethyl lead. This is another
           | environmental issue that should be addressed.
        
         | std_badalloc wrote:
         | I've seen studies where they tracked wild Norwegian salmon, and
         | found that 90% died before spawning. As far as I understood it,
         | this was interpreted as "natural death", but it's the same
         | figure as the one in the article. It seems like a very
         | plausible explanation that those deaths also largely occurred
         | due to the same poisoning from tires.
        
       | remote_phone wrote:
       | They use shredded tires in children's playgrounds as artificial
       | turf. A few years ago a soccer coach made the connection between
       | that turf and children getting weird cancers and has been
       | campaigning against them ever since.
       | 
       | It looks like tires are much more toxic than we thought and we
       | should reconsider their composition quickly.
        
         | sjg007 wrote:
         | Yeah a couple of professional goalies got lymphoma too.
        
         | 08-15 wrote:
         | That's terrible! All the salmon in the playground will die!
        
         | reachtarunhere wrote:
         | Do you have a link for this?
        
           | andrevoget wrote:
           | https://www.reuters.com/article/uk-usa-health-turf-
           | idUSKCN0V...
        
         | throwaway201103 wrote:
         | Because youth soccer coaches are well known for their
         | contributions to cancer research?
         | 
         | Contrast that to the treatment given over the past 10 months to
         | any non-expert who dared voice an opinion on COVID-19.
        
         | artvark11 wrote:
         | As a kid, I remember playing at playgrounds made entirely of
         | old tires. Shedded tires on the ground, big farm tractor tires
         | to climb on. Car tires stacked up to form towers. I wonder what
         | impact that had on the thousands of kids that passed through
         | there.
        
           | sjg007 wrote:
           | I feel like the best option is to recycle the tires into
           | tarmac and reuse as much into new tires as well. The other
           | thing is to live far away from major roads.
        
             | mattbk1 wrote:
             | Recycling into roads sort of sucks for people who live near
             | roads already (among all the other stuff they have to
             | breathe in from car exhaust).
        
           | abacadaba wrote:
           | and we were so proud of using all that recycled material too.
        
             | dwaltrip wrote:
             | Seems the problem is not the recycling, but the composition
             | of the items being recycled.
        
       | gmueckl wrote:
       | I hope that the industry puts the required changes in place
       | really soon and that it has the expected effect on Puget Sound.
       | Are there any guesses whether a healthier salmon population would
       | help the local Orcas as well?
        
       | ur-whale wrote:
       | https://archive.is/VvOTH
        
       | Iwan-Zotow wrote:
       | Putin?
        
       | 14 wrote:
       | To the person [1] who said tires don't matter I guess we can have
       | this discussion again?
       | https://news.ycombinator.com/item?id=23613705
        
       | [deleted]
        
       | degenerate wrote:
       | Non-paywall link: https://archive.is/VvOTH
        
       | marknutter wrote:
       | Humans. Was it humans?
        
       | MrBuddyCasino wrote:
       | Great that they were able to identify a clear candidate. This
       | type of testing of course can't be done on humans to eg identify
       | hormone disruptors. Are there other methods to verify such
       | damaging chemicals, or are we condemned to live with permanent
       | small-scale damage?
        
         | londons_explore wrote:
         | Big datasets matching health outcomes to blood sample
         | spectroscopy seems like a good candidate for identifying
         | chemicals which detrimentally affect human health by small
         | amounts.
         | 
         | Obviously you won't be able to separate cause and effect, but
         | in my view if "X chemical in people's blood leads to a higher
         | likelihood of dropping out of school", thats a good enough
         | reason to restrict the use of X, even if it sometimes turns out
         | there is no causal effect.
        
           | robocat wrote:
           | It is a statistical nightmare to do what you suggest.
           | 
           | 1. False correlations:
           | https://en.wikipedia.org/wiki/Data_dredging
           | 
           | 2. True correlations:
           | https://en.wikipedia.org/wiki/Confounding
           | 
           | 3. The number of normal compounds in our body from cell
           | processes or digestion is large. Measuring tiny amounts of
           | unknown compounds is extremely hard in that environment.
           | 
           | A better way is to proscribe more in-depth testing of
           | compounds on animals. Removing all other factors gives
           | statistical power to observations.
        
         | sjg007 wrote:
         | We could. I mean lead is commonly identified by blood test.
        
         | quotemstr wrote:
         | But this type of testing _can_ be done on near-human primates
        
           | xiphias2 wrote:
           | It's just much more expensive to grow monkeys than growing
           | fish.
        
         | im3w1l wrote:
         | Black box modelling by trying different thing on humans is
         | hopeless. We will have to figure out the mechanisms.
        
       | josephjrobison wrote:
       | TLDR;
       | 
       | The killer was the 6PPD-quinone from the tires in the roadway
       | runoff.
        
       | Bermion wrote:
       | "The team is in conversations with the tire industry and hopes
       | manufacturers will be willing to look for a replacement
       | preservative" - Is this how it usually works? I'd think they
       | should contact some regulator that makes sure tires containing
       | this cannot be sold. Companies don't do things to be nice.
        
         | lawnchair_larry wrote:
         | The manufacturers are not stupid, they know the next stop will
         | be legislators. Companies prefer to get ahead of things and
         | self-regulate if they know that the alternative is almost
         | certainly going to be government bureaucrats stepping in (which
         | they will anyway - this is going to be like BPA). The results
         | are damning enough that they probably don't want to waste any
         | time, and finding an alternative will probably take some
         | research.
         | 
         | Note that they said this affects _every tire on the market_ ,
         | so this isn't a case of reporting a few manufacturers. This is
         | going to result in an industry-wide change.
        
         | hh3k0 wrote:
         | I'm surprised, too. And the companies in question should be
         | fined quite substantially, in my opinion. We need to create
         | incentive for them to actually research the possible
         | detrimental environmental impact of their products --
         | scientists shouldn't have to beg them to use substitutes and
         | the matter shouldn't be settled with the companies responding
         | something along the lines of "whoops, we didn't know that."
        
           | voxic11 wrote:
           | Yeah, the tire companies deserve some fines, but I think the
           | drivers who smeared these tires all over the roads are even
           | more responsible for the environmental impact. The drivers
           | should be allowed to get away with "whoops, we didn't know
           | that.".
        
             | Tagbert wrote:
             | I don't suppose that any products that you use have
             | unexpected impacts? Have you done the research?
             | 
             | It's silly to expect consumers to verify safety upfront. if
             | products are shown to be toxic and alternatives exist, then
             | you can start expecting consumers to choose the less toxic
             | version.
        
             | hh3k0 wrote:
             | I disagree with that sentiment. I do not consider the
             | consumer to be the one responsible of researching the
             | safety of a product, the responsible party is clearly the
             | one that produced and marketed the product.
        
         | throwaway201103 wrote:
         | > Companies don't do things to be nice.
         | 
         | They do if it gives them a market advantage. If Goodyear can
         | market tires that are more "sustainable" or "eco-friendly" than
         | their rivals that will resonate with consumers who focus on
         | such things (many of them, particularly millenials and
         | younger).
         | 
         | We saw this with trans-fats in food. They aren't prohibited by
         | the FDA, but most producers have eliminated them and have "Zero
         | Trans Fats" emblazoned across the package labeling, because it
         | sells better. Seeing this effect also with high-fructose corn
         | syrup.
        
           | uoaei wrote:
           | That's the point. They don't do it _to be nice_ , they do it
           | _because it helps the bottom line_. I don 't think it's
           | helpful nor accurate to conflate the two, as it only serves
           | corporations who want to ride on paper-thin "social
           | responsibility" PR.
        
             | throwaway201103 wrote:
             | I guess I don't see the difference.
             | 
             | People running the corporations who decide to be "socially
             | responsible" are "being nice." The reason they do it is
             | because their customers want/will pay for "social
             | responsibility." If nobody wants social responsibility, why
             | would it fall on corporations to do it anyway? Why do they
             | get demonized and everyone else gets off the hook?
        
               | uoaei wrote:
               | You don't see the difference likely because your moral
               | value system prioritizes outcomes instead of intent. This
               | is not a bad way of looking at it and I'm not criticizing
               | that perspective.
               | 
               | They get demonized because there is nothing stopping them
               | from simply undoing all those policies once the bottom
               | line dictates otherwise. The public cannot trust
               | corporations who act in that way, and when they
               | inevitably do, they get valid criticism for it. They are
               | using language in sinister and misleading ways, and for
               | most people that is equivalent to lying.
        
           | greeneggs wrote:
           | Trans fats were banned by the FDA: https://www.washingtonpost
           | .com/news/wonk/wp/2018/06/18/artif...
        
         | Iv wrote:
         | Right now, the question to answer is "how much would it cost to
         | use a different chemical?" and the answer could be "Oh, we just
         | have to use one of the 100 different ones from our catalog,
         | that's barely a tenth of a cent of difference" or it could be
         | "no can do, this is a crucial molecule that prevents tires from
         | rotting in winter."
         | 
         | Once you know that, you can approach regulators who will have
         | to weight between the interests of the fish industry and the
         | interests of the tires industry.
        
           | grawprog wrote:
           | >who will have to weight between the interests of the fish
           | industry and the interests of the tires industry.
           | 
           | This bothers me. It's not about the 'fish industry' it's
           | about weighting the interests of the tire industry against
           | the life in the Puget sound ecosystem.
           | 
           | https://wildsalmoncenter.org/why-protect-salmon/
           | 
           | >Few animals have been as central to the Pacific human
           | experience as salmon. Their annual migrations are a miracle
           | of nature. They feed us and their presence tells us that our
           | rivers are still healthy. From grizzly bears to orca whales,
           | at least 137 different species depend on the marine-rich
           | nutrients that wild salmon provide
           | 
           | >Salmon and freshwater ecosystems are inextricably linked by
           | feedbacks between salmon runs, food webs, and riparian
           | forests. Salmon runs function as enormous pumps that push
           | vast amounts of marine nutrients from the ocean to the
           | headwaters of otherwise low productivity rivers. For example,
           | sockeye salmon runs in southwest Alaska contribute up to 170
           | tons of phosphorous per year to Lake Illiamna. These
           | nutrients are incorporated into food webs in rivers and
           | surrounding landscapes by a host of over 50 species of
           | mammals, birds, and fish that forage on salmon eggs,
           | juveniles, and adults in freshwater. Predators, such as brown
           | bears, disperse these marine nutrients into surrounding
           | forests, enhancing the growth of stream-side trees that shade
           | and protect stream banks from excessive erosion
        
             | throwaway201103 wrote:
             | If its really that localized, why doesn't the state of
             | Washington just ban the chemical? Not unprecidented for a
             | state to have its own environmental regs that are stricter
             | than national regs. And since there are no salmon migrating
             | up rivers in Kentucky, it should be less of a concern there
             | and you don't need to spend effort/political favors getting
             | the support from the Kentucky delegation in congress.
             | 
             | Sure it would not be perfect, because you would still have
             | out-of-state vehicles using the roads, but it would be an
             | improvement that could probably get done a lot faster and
             | it might be enough.
        
               | grawprog wrote:
               | >why doesn't the state of Washington just ban the
               | chemical?
               | 
               | Is it just salmon affected by this chemical?
               | 
               | It looks like Kentucky has both cutthroat and rainbow
               | trout. Both of which are actually species of salmon in
               | the genus Oncorhynchus, which are true salmon.
               | 
               | Would they be affected by the chemical?
               | 
               | How about other species of fish?
               | 
               | That's the thing about this kind of stuff, it's not
               | necessarily localized. There's a lot we don't know about
               | ecosystems and the long term effects of chemicals like
               | this. Chances are though, if it affects one area in such
               | a negative way, it'll have other negative effects.
        
               | mattgrice wrote:
               | This research was motivated by the runoff effect being
               | especially acute in coho salmon.
               | 
               | It probably affects other species, too. Now that we know
               | the chemical responsible it will be easier to test that.
        
               | throwaway201103 wrote:
               | Well start with what we know. We have a problem in the
               | Puget Sound area. I'm not hearing anything about trout in
               | Kentucky.
               | 
               | A lot of environmnental regulation got its start with
               | regulation in California that spread from there. It's
               | easier to get something passed locally than to get
               | national support from day one.
        
               | munificent wrote:
               | _> I 'm not hearing anything about trout in Kentucky._
               | 
               | That probably says more about environment research
               | funding in Kentucky than it does their fish.
               | 
               | Washington is one of the most pro-science states in the
               | US, the Puget Sound area has one of the greatest
               | concentration of environmentally focused people, and
               | salmon are historically deeply ingrained in Washington
               | culture. If it took all of that to garner enough
               | resources to discover this problem, imagine all of the
               | other environmental disasters out there that we're simply
               | oblivious to.
        
         | HomeDeLaPot wrote:
         | I suppose tire companies might be willing to find a replacement
         | in order to skip the potential regulations and bad PR.
        
         | russell_h wrote:
         | It makes sense to start with the companies: if they view this
         | as something that will inevitably be regulated there is a
         | reasonable chance they'll just comply voluntarily to save the
         | bad PR. They might even see an opportunity for good PR.
         | 
         | This approach, if successful, will be way faster than starting
         | with regulation.
        
           | minikites wrote:
           | I think this is incredibly naive. If bad PR worked, there
           | would be a lot more companies going bankrupt.
        
         | 08-15 wrote:
         | It's probably in the tires _because_ of regulation, and it
         | cannot be taken out without a suitable replacement and without
         | relaxing some other requirement on the tires.
         | 
         | Apparently, 6-PPD is there to scavenge ozone. If that ozone
         | doesn't have anything harmless to react with, it reacts with
         | the rubber, which makes it brittle. Ozone scavengers prolong
         | the life of the tire, and make it safer.
         | 
         | Companies don't do things because they are James Bond villains,
         | either.
        
         | jacurtis wrote:
         | My concern with this is that it will likely take at a minimum
         | 1-2 years for tire manufacturers to research new compounds that
         | eliminate this chemical. Then it will take probably another
         | year, at best, before manufacturing plants are transitioned
         | over to build this new compound and we start to see the new
         | compound trickle down into new tires. Then it will take 2-4
         | years to propagate that compound across the entire product line
         | and/or industry.
         | 
         | Once the compound is readily available across the industry,
         | then we can rest assured that new tires will be "safe". But
         | tires have a usable life of 2-5 years depending on the type of
         | tire. So it will take many more years before people with "non-
         | safe" tires purchase new ones that are "salmon-safe". Remember
         | also that some people (generally as a result of financial
         | concern) may drag tire use out to 8 or even 10 years.
         | 
         | This puts a timeline for "safe tires" at 10-20 years from now!
         | I hate to shout "doomsday", but the Salmon may not have that
         | long. Salmon only live 2-3 years on average before spawning.
         | According to this article, 90% of them are dying due to this
         | chemical during their trip up Puget Sound urban rivers to
         | spawn. Salmon are already operating at low population rates. So
         | we may not have decades to sit and figure this out.
         | 
         | As a more immediate alternative, I would like to see if there
         | is a way to neutralize or catch this 6PPD chemical with some
         | type of "filter" in the road runoff pipes or a road-coating
         | that could be installed in critical areas. This would seem like
         | a more immediate solution that wouldn't require global or
         | national "buy-in" from tire manufacturers.
         | 
         | And of course all this assumes that tire manufacturers care
         | enough to save the salmon. This is the type of thing that
         | regulation is useful for instead of relying on tire
         | manufacturers to "do the right thing".
        
           | munificent wrote:
           | _> This puts a timeline for  "safe tires" at 10-20 years from
           | now!_
           | 
           | No, it puts a maximum end date for 100% removal at 10-20
           | years. Incremental progress can happen much sooner. What you
           | describe is basically the speed that most large-scale changes
           | occur at. It's just how it goes.
           | 
           |  _> I hate to shout  "doomsday", but the Salmon may not have
           | that long. Salmon only live 2-3 years on average before
           | spawning._
           | 
           | The salmon will bounce back. It is a real concern and problem
           | that we need to fix, but we are not on the brink of
           | extinction and don't need to panic.
           | 
           |  _> According to this article, 90% of them are dying due to
           | this chemical during their trip up Puget Sound urban rivers
           | to spawn._
           | 
           | 90% _in some streams._ That 's the worst case number, but
           | there are many streams in Washington, many of which are not
           | in urban areas.
        
             | ncmncm wrote:
             | Several Pacific Northwest US salmon species are on the
             | brink of extinction. Tire pollution is one of several
             | independent attacks on them. When they're gone, we won't
             | quarrel over which really did them in.
        
               | ip26 wrote:
               | This chemical only seems to affect Coho - which is part
               | of the puzzle.
        
             | carlmr wrote:
             | I think it would be acceptable to regulate more harshly
             | where the salmon live. Make regulations that force getting
             | the new tires as soon as possible if you live within 100
             | miles of a river with salmon or your commute touches this
             | zone.
             | 
             | That way you could get the results in 2-3 years with a
             | minimal extra cost because only a small part of the US and
             | Canada have to renew their tires earlier.
        
           | chrisbrandow wrote:
           | There is not likely to be a way to catch enough runoff to
           | prevent this.
        
       | jeffrallen wrote:
       | Wonder if we need to rethink tyres from first principles. Maybe
       | Elon Musk can do it. Instead of tweeting.
        
         | leesec wrote:
         | Lol? Maybe you could do it instead of posting? I don't
         | understand.
        
       | splicer wrote:
       | It's ironic that the toxicologist's name is McIntyre!
        
       | Scoundreller wrote:
       | tldr: " The killer was the 6PPD-quinone from the tires in the
       | roadway runoff."
       | 
       | 6PPD is an antioxidant added to tires, and the -quinone is the
       | oxidized form (not sure if it oxidizes before/during/after
       | manufacturing or after escaping the tire).
        
         | JKCalhoun wrote:
         | I wonder how long the industry has been adding 6PPD to tires?
         | For better or worse we got along _without_ adding this to tires
         | in the past.
         | 
         | Cracked tires: dangerous? Cosmetic? Or early warning that tires
         | are getting old?
        
           | themaninthedark wrote:
           | Your tire is a pressure vessel. Cracks in in will be weak
           | points. Your tire is thinner on the sides then the working
           | face.
           | 
           | Ozone in the atmosphere react with the tire compound and
           | weakens it, leading to cracks forming which exposes more and
           | more area deeper in the tire body to ozone. increased area
           | increases chance of reaction.
           | 
           | A tire that has recently been inflated to the upper limit of
           | it's pressure range making stiff is traveling at 70 miles an
           | hour, suddenly there is a spike in pressure as if hits a
           | bump. The sidewall is weak.... How will this failure end?
           | 
           | Tire are not a fixed technology, the companies are always
           | having to create and reformulate to drive the price lower,
           | last longer, have better traction.
        
           | canada_dry wrote:
           | Good question. Of course, like many things, the answer
           | usually is: _the moment they discovered the 6PPD was a cheap
           | substitute for xyz_.
        
         | Grazester wrote:
         | An article I read last week said from micro plastic from tire
         | wear entering the water as runoff from the land.
        
           | JoeAltmaier wrote:
           | Same thing? Its the chemical leaching from the rubber
           | particles in the river.
        
             | Grazester wrote:
             | Yes its chemical leaching.
             | 
             | "The researchers determined that the chemical is formed
             | when a preservative known as 6PPD reacts with ozone. 6PPD
             | is designed to extend the lifespan of tires by reacting
             | with ozone in the surrounding air before it has a chance to
             | interact with the rubber and weaken it, Kolodziej said."
             | 
             | https://www.popsci.com/story/environment/coho-salmon-
             | toxic-c...
        
         | dschuler wrote:
         | Based on the Wikipedia entry [0], it looks like 6PPD binds to
         | the extra oxygen atom in ozone to convert it to regular O2, so
         | it would be used during the life of the tire to prevent
         | cracking.
         | 
         | I just read that ozone will cause cracks in regular rubber
         | bands over time, I never knew that was the cause [1].
         | Interesting.
         | 
         | [0] https://en.wikipedia.org/wiki/6PPD [1]
         | https://en.wikipedia.org/wiki/Ozone_cracking
        
       | hikerclimb wrote:
       | Bad. I think salmon should die so we don't have food
        
       | stfp wrote:
       | Our whole understanding and approach with regards to risks from
       | industrial chemicals is so completely off...
       | 
       | We keep churning out new compounds (~2000 every year??!) or new
       | use cases for existing ones at insane scale or speed because
       | "most of them are safe". Except the ones that aren't cause a wide
       | range of damage, take 15 years to identify as causes, 15 more
       | years to ban, 15 more to leave the ecosystem if they do at all,
       | and are often replaced by minor variations that haven't been yet
       | proven dangerous.
       | 
       | It seems to me these things should be considered unsafe by
       | default, tested at small scale for years, proven to be bio-
       | degradable and if used at scale introduced very slowly... which
       | in many cases won't be possible, which will readjust our stance
       | so we only use them when absolutely critical and necessary vs.
       | eg. putting teflon or PFAS in literally everything because why
       | not.
       | 
       | The other thing is individual accountability: chemical engineers
       | who facilitate this insanity should be held responsible. Putting
       | lead in gasoline and CFCs in the atmosphere used to get you
       | medals, now similar "inventions" should get you a jail term
       | proportionate to the damage caused.
        
         | doitLP wrote:
         | Agreed. The same thing happened with BPA -- banned in toys and
         | bottles after decades of harm to be replaced by at least 40
         | other chemicals that haven't proven to be unsafe -- yet.
        
         | bencollier49 wrote:
         | The precautionary principle, which is what you describe, is in
         | greater use in Europe.
         | 
         | https://ec.europa.eu/environment/integration/research/newsal...
        
         | whatshisface wrote:
         | > _The other thing is individual accountability: chemical
         | engineers who facilitate this insanity should be held
         | responsible._
         | 
         | How would they be expected to know what the results of their
         | chemical will be? Drug companies focus exclusively on
         | biological effects and can't even get drugs to regularly pass
         | phase 1 trials, and you're asking for a single chemist at
         | Industrial Sealants Inc to do what entire pharma companies
         | can't? Putting lead in gasoline sounds dumb, but so does
         | putting mercury in vaccines. The only way to tell the
         | difference is to do studies, which would take teams of people.
         | It is absolutely not possible to expect individual chemists to
         | accurately predict the biological consequences of their
         | products.
        
           | mcguire wrote:
           | Be careful about diluting responsibility---if everyone can
           | point to someone else, no one will make a hard (and not
           | immediately profitable) decision.
           | 
           | In all of those studies, etc., there is someone at the top
           | who does, and should, make the ultimate decision, just like
           | when building a bridge, there is an engineer who puts his
           | career on the line.
        
             | whatshisface wrote:
             | If you're going to assign responsibility, you need to
             | assign it to people who know the right decision to make. If
             | you assign responsibility to a janitor or a chemist for any
             | torts set against the company, then janitors and chemists
             | will simply quit working there. The only person who could
             | begin to approach responsibility would be an executive with
             | the authority to organize and pay for clinical trials and
             | toxicity studies.
        
           | bsder wrote:
           | > so does putting mercury in vaccines
           | 
           | Putting a known biologically tested and FDA cleared
           | _preservative_ into vaccines is not  "dumb".
           | 
           | Having to remove said preservative because because people
           | committed medical fraud (and later lost their licenses) to
           | create fear about it and because a bunch of people picked up
           | on it as a desperate, now-negatively validated reason for
           | their child having autism?
           | 
           |  _That 's_ dumb. But the manufacturers did it anyway because
           | _people_ are dumb.
        
             | whatshisface wrote:
             | You missed the phrasing slightly. I said they both _sound_
             | dumb, and it 's only testing that can distinguish them. In
             | an alternate universe, it's leaded gasoline that is safe
             | and mercury in vaccines that is poisoning people.
        
               | refactor_master wrote:
               | But in this universe, you can eat a can of tuna and have
               | both!
        
           | tehjoker wrote:
           | Maybe we should have tiered rules for how much testing is
           | done based on the number of tons that are going to be
           | produced and how they are being disposed of.
           | 
           | (And if we already do, then the rules for the higher tiers
           | need to be tightened.)
        
             | whatshisface wrote:
             | Given the extreme differences in badness per ton I'm not
             | sure if that's a reasonable metric. Maybe instead we could
             | mandate yucca mountain level storage for everything that
             | hasn't been evaluated, and then let companies decide for
             | themselves whether or not they will be making enough of the
             | stuff to justify studying how to dispose of it more
             | cheaply.
        
               | tehjoker wrote:
               | It might be possible to establish categories where if
               | your molecule has XYZ properties it falls into this
               | bucket. I think a category for really novel molecules
               | that haven't been evaluated is a good idea with tight
               | restrictions on how much can be produced.
               | 
               | There should also be a presumption that minor edits to
               | known dangerous molecules should be presumed dangerous
               | without testing.
        
           | ncmncm wrote:
           | Putting mercury in vaccines was also dumb. It is impossible
           | to quantify the damage _just_ from the direct consequence of
           | people beginning to avoid vaccines because of it. They don 't
           | put mercury in vaccines anymore.
        
         | chrisbrandow wrote:
         | This has lots of practicality problems, obviously.
         | 
         | The individual accountability is certainly tough, particularly
         | since we learn about impacts only over time. And discoveries
         | like these are studied, applied and distributed by ultimately
         | hundreds to thousands of people.
        
         | mdavis6890 wrote:
         | The problem with the Precautionary Principal (that you seem to
         | describe) is that it doesn't account for opportunity cost. New
         | compounds are developed for a reason and to contribute some
         | value to society. That could be a very small convenience
         | optimization, or could be for a life-saving purpose.
         | 
         | While we're waiting for some compound to be deemed 'safe' for
         | some particular use, society is missing out on the benefits of
         | that use.
         | 
         | The COVID vaccine is a very timely example of this. It/they
         | haven't gone through nearly the amount of testing and trials
         | that are normally required. But we're going ahead with it
         | anyway, since waiting would cost more lives. This is a
         | judgement call that some set of fallible humans has made. Easy
         | in this huge, public, major case. But for the thousands of
         | compounds developed yearly, who decides this, and at what cost
         | to society in lives, quality of life and resources?
         | 
         | And this doesn't count the resources that society has to spend
         | to make the determination of safety, which have their own
         | opportunity cost as well.
        
           | stfp wrote:
           | Taking a step back: here, incidentally, they were trying to
           | basically facilitate driving, which is not really in the
           | interest of society / life on the planet -\\_(tsu)_/-
           | 
           | Maybe the vaccine is actually a bad idea? I don't think so.
           | 
           | But even if it turned out to have terrible side effects, that
           | would only affect people (the people alive now and taking the
           | vaccine) and not the environment (all the humans and other
           | animals, present and future).
        
         | dgemm wrote:
         | Probably the best known example of this (who I assume you are
         | referring to) is incidentally responsible for both leaded fuel
         | _and_ CFCs:
         | 
         | https://en.wikipedia.org/wiki/Thomas_Midgley_Jr.
        
           | weaksauce wrote:
           | there was a fun dollop episode about him if you want a little
           | levity while listening to an absolute ecological monster...
           | https://soundcloud.com/the-dollop/393-thomas-midgley
        
           | triceratops wrote:
           | He also appears on this amazing list: https://en.wikipedia.or
           | g/wiki/List_of_inventors_killed_by_th...
        
         | minikites wrote:
         | >It seems to me these things should be considered unsafe by
         | default, tested at small scale for years, proven to be bio-
         | degradable and if used at scale introduced very slowly
         | 
         | That's no way to create shareholder value.
        
         | derbOac wrote:
         | Underlying this all is a sort of scientism issue. On the one
         | hand you have a culture that assumes the framework of a
         | scientific framework is "truth" and that the lingua franca of
         | risk should be demonstrable evidence. On the other is a culture
         | that denies the realism of the scientific studies, and sees
         | risk in misrepresentative evidence.
         | 
         | Generally speaking, the latter camp gets labeled as
         | "antiscientific" by the former, and the former gets labeled as
         | "elitist" or having conflicts of interest. It's part of a theme
         | that seems to be popping up a lot in the last several years or
         | so in numerous settings: which is worse, lack of evidence or
         | misleading evidence?
         | 
         | This example with the salmon is interesting to me because (if
         | I'm understanding it correctly), the compound in the tire isn't
         | the problem, it's a byproduct of tire breakdown. So I could see
         | a chemist in the lab sitting there saying "ok we ran our tests
         | on X it's fine" without understanding that in the real world, X
         | reacts and breaks down into other compounds that are
         | problematic. It's kind of a prime example of how the scientific
         | model isn't the correct one to be using in the first place.
         | Within the bounds of the model, X is fine, but the model is
         | wrong as a representation of reality, so the conclusions are
         | wrong.
         | 
         | I think underlying a lot of this are differing ideas of what is
         | "scientific", or what constitutes the universe of risks. I
         | don't see this dynamic changing until certain cultures
         | surrounding scientific authority change.
        
           | ska wrote:
           | > It's kind of a prime example of how the scientific model
           | isn't the correct one to be using in the first place.
           | 
           | This seems to be a category error - after all it was science
           | that found the problem also.
           | 
           | I think you are poking around the edges of something real
           | here, but suspect the thinking is muddy still and falling
           | into a false dichotomy. There _is_ a lot of confusion about
           | the role of science and what it can and can 't do, but I
           | don't think it maps at all purely onto the "culture wars" as
           | you are seeming to suggest.
        
           | xapata wrote:
           | > the scientific model
           | 
           | What you described isn't "the scientific model" but merely
           | one flawed study. Science is the process of learning about
           | the world. Scientific paradigms change. Right now we seem to
           | have a statistical frequentist paradigm in most fields, but
           | it's shifting towards Bayesian. The business science field
           | still seems stuck in the case study / anecdote paradigm,
           | though it's also shifting.
           | 
           | If the science doesn't seek to learn about "the real world"
           | then it's bad science.
        
           | whatshisface wrote:
           | > _It 's kind of a prime example of how the scientific model
           | isn't the correct one to be using in the first place._
           | 
           | What's your proposed alternative to science for determining
           | the products of tire breakdown? Asking psychics? Polling
           | facebook moms? Voting on it in Congress?
        
             | monkeycantype wrote:
             | The scientific method enables us to rigorously build
             | models.
             | 
             | But it takes effort, so the model only expands in the
             | directions where a person chooses to the do that work.
             | Scientific models are a communal human artefact, flawed
             | with the bias and inattention of those that built them.
             | 
             | The is a lot we know about the world, from history, from
             | our experience, that we are not able to express with enough
             | rigor to include them in a scientific model.
             | 
             | So we can be confident that our scientific understanding of
             | any new compound, will not gives us a complete
             | understanding of the impact of that compound in the world.
             | From history we have a partial map of our ignorance. We
             | know from past experience that there are realms of unknown
             | - ecological effects, decomposition products, birth
             | defects, health impacts - associated with new products. We
             | know there is a very big difference between safe and no
             | known adverse impacts
             | 
             | Rather than an alternative to science, we need a more
             | vigorous meta model, better appreciation of where the model
             | ends, and a better model for how we should act given our
             | ignorance. I don't think we lack the ability to do this,
             | it's a matter of will and power.
        
             | stfp wrote:
             | Look up scientism.
             | 
             | The whole point is we need to accept that no single method
             | will give us this kind of visibility and understanding, and
             | given that fact we should be more careful about certain
             | things, especially things we just seem to keep
             | miscalculating and that have long-lasting, terrible
             | effects.
             | 
             | That's _actual science_ vs. commercial /industrial
             | marketing masquerading as science.
        
             | hombre_fatal wrote:
             | Unfortunately, alternatives to science are being pushed
             | right now in the current culture war. Google "other ways of
             | knowing".
             | 
             | Worth pointing out just because your appeal to absurdism
             | (which most of us would agree with) is losing steam in the
             | marketplace of ideas.
        
           | the_af wrote:
           | > _It 's kind of a prime example of how the scientific model
           | isn't the correct one to be using in the first place_
           | 
           | Do you mean "this particular scientific model" (which lacks
           | the analysis of byproducts) or the scientific _method_? If
           | the latter, what other method would you use instead?
        
             | FooHentai wrote:
             | The issue is that you can't prove a negative, not even the
             | scientific method can achieve this. So you can prove harm,
             | or benefits, but you can't prove an absence of harm.
             | 
             | So while the scientific method is fine, applying it without
             | an abundance of caution commensurate to the potential
             | negative impacts leads to poor outcomes in the long run.
        
               | zamadatix wrote:
               | You can't truly "prove" harm or benefits either they just
               | happen to be things you can very easily make the error
               | bounds minuscule on. Likewise the problem with "absence
               | of harm" is making the error bounds small is extremely
               | slow and costly so we avoid it. The scientific method (or
               | any method to this point) never ends up "proving"
               | anything, you always have to set what error bounds are
               | acceptable.
               | 
               | Which leads to the real overall point I suppose - is
               | there something better we could be using as "just never
               | make anything new" isn't free of problems either so it's
               | a question of "what's the best method" not "what method
               | can guarantee something" (none so far can).
        
           | meowface wrote:
           | The solution to poor results from scientific work is better
           | scientific work, not throwing out the scientific model.
           | 
           | The issue described is akin to testing some new code with
           | unit, integration, and end-to-end tests, and running it for
           | some time in a dev environment, but not running it in a QA
           | environment that mirrors production, and not monitoring it
           | for issues when it does get deployed to production.
           | 
           | The response there wouldn't be "the test/devops model isn't
           | the correct one to use in the first place", it's that the
           | testing and QA was inadequate because it only looked at an
           | idealized model of reality and didn't consider "where the
           | rubber meets the road" (literally). Testing something in
           | isolation is insufficient, since you need to test the
           | downstream effects and potential complex interactions with
           | everything else in the environment.
           | 
           | There is no testism problem; only a poor testing problem.
           | Unless, as you say in your last sentence, one is just arguing
           | about definition semantics - e.g. if "QA" falls under
           | "testing", or, here, if "real-world observation" falls under
           | "scientific testing". I'd argue both do. I think your
           | concerns might be better phrased as "lab model" and "lab-
           | ism".
        
         | zug_zug wrote:
         | I guess my proposal is that new chemicals need to be tested at
         | a 100x dose on 15 different species, up to primate. On lesser
         | species, things such as number of offspring need to be measured
         | (reproductive health seems to be the first to go a lot of
         | times). On primates, we'd look for sperm count relative to a
         | control group (again the first thing to go).
         | 
         | If any effect is seen at a 100x dose (of the amount expected to
         | be ingested) the chemical would be dropped.
        
           | cogman10 wrote:
           | IDK, I think disposal and recycling is really where we need
           | to focus.
           | 
           | Some chemcials are damn useful while being toxic. I don't
           | think the right thing to do is banning all toxic chemcials
           | because they might cause environmental damage. Instead, let's
           | focus on figuring out safe handling upfront.
           | 
           | A good example of this is batteries. Super toxic, super
           | useful.
        
             | doitLP wrote:
             | Damn useful but at what cost? Unfortunately we often don't
             | know the cost until 10 to 50 years on. It's impossible to
             | close Pandora's box once it's open. Look at DDT
             | https://www.latimes.com/projects/la-coast-ddt-dumping-
             | ground... and mercury in the food chain and and and and
        
               | DennisP wrote:
               | I think GPs point is to keep them contained while in use,
               | with a plan to keep them out of the environment once
               | you're done with them.
               | 
               | Batteries are a great example. We really need good
               | battery recycling. We also really need good batteries,
               | since it looks like they'll play a major role in
               | preventing catastrophic global warming.
        
           | kjs3 wrote:
           | No.
           | 
           | First, what is a 'dose' for a new chemical?
           | 
           | Second, there are all sorts of critical things that if you
           | took 100x the recommended dose you would see a significant
           | negative physiological effect. Like salt. Or water.
           | 
           | This is a _far_ more nuanced problem that  "let's just shoot
           | up some monkeys with a gallon of the stuff and see if their
           | nuts shrivel up". In fact, that sort of reductionist approach
           | is why we have this problem.
        
           | uoaei wrote:
           | Strong acute exposure and slow chronic exposure will show
           | different effects overall. But yours sounds like a decent
           | heuristic as a first pass.
        
         | fh973 wrote:
         | In the EU new substances seem to need registration at least.
         | It's called REACH regulation:
         | 
         | https://echa.europa.eu/regulations/reach/understanding-reach
        
         | consumer451 wrote:
         | > It seems to me these things should be considered unsafe by
         | default, tested at small scale for years, proven to be bio-
         | degradable and if used at scale introduced very slowly...
         | 
         | It sounds like you are describing the Precautionary Principle,
         | which is unfortunately made light of here due to its impact on
         | GMO food adoption in the EU. I do agree with you, but this idea
         | seems to go against the hyper-growth form of capitalism which
         | is generally accepted as the only option in the USA.
         | 
         | https://en.wikipedia.org/wiki/Precautionary_principle
         | 
         | https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=LEGISSUM...
        
         | aardvarkr wrote:
         | >The other thing is individual accountability: chemical
         | engineers who facilitate this insanity should be held
         | responsible.
         | 
         | Hey, I wanted to point out for your future reference that you
         | really should be blaming the chemists. They're the ones who
         | design the product and intentionally choose this. Chemical
         | engineers are the ones who do the manufacturing of chemical
         | products. I have CE friends and they're the ones in the plants
         | keeping processes running
        
           | stfp wrote:
           | Thanks, good clarification!
        
       | sradman wrote:
       | The paper _A ubiquitous tire rubber-derived chemical induces
       | acute mortality in coho salmon_ [1]:
       | 
       | > In U.S. Pacific Northwest coho salmon (Oncorhynchus kisutch),
       | stormwater exposure annually causes unexplained acute mortality
       | when adult salmon migrate to urban creeks to reproduce. By
       | investigating this phenomenon, we identified a highly toxic
       | quinone transformation product of
       | N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine) (6PPD), a
       | globally ubiquitous tire rubber antioxidant.
       | 
       | [1]
       | https://science.sciencemag.org/content/early/2020/12/09/scie...
        
       | throwawaysea wrote:
       | Runoff carries all sorts of things into waters, and I think the
       | issue is particularly bad when you have large denser areas like
       | Seattle, since the concentration of unwanted chemicals in local
       | waters can be huge. For example opioids from Seattle's street
       | level drug abuse can be found in local marine life:
       | https://www.npr.org/sections/thetwo-way/2018/05/25/614593382...
        
       | loraa wrote:
       | spoiler: it's a bear.
        
       | Tepix wrote:
       | So, are there any tire manufacturers that advertise their tires
       | as being 6ppd free? I'd buy them.
        
         | rini17 wrote:
         | It will end up like "BPA-free" beverage cans. Manufacturers
         | just slightly change the chemical structure or use another
         | plastic with not yet known adverse effects.
        
           | m_eiman wrote:
           | Which is why it's a tragedy that the EU chemical regulations
           | weren't allowed to be based on a "you can use it if you can
           | show it's safe" instead of "you can use it until someone else
           | shows it's unsafe" principle. That would have been good.
        
             | Karunamon wrote:
             | Also impossible. Proving something safe is like proving a
             | negative - proving a lack of something (harm).
        
               | bawolff wrote:
               | That doesn't mean you can't require a certain amount of
               | safety testing.
        
               | Karunamon wrote:
               | You can only reasonably test for acute effects. Chronic
               | effects are only ever going to be found in large cohorts
               | (i.e. public consumption) over a long period of time.
        
             | kjs3 wrote:
             | Define 'safe' and 'unsafe'. That's not as easy as it seems,
             | and it would be the source of endless bickering between
             | business and the regulators.
        
             | bzb6 wrote:
             | It would be impossible to prove that a new chemical is safe
             | until after decades of widespread use. Lab tests can only
             | go so far
        
             | Gunax wrote:
             | I am not sure how this would work. For instance, what
             | animals would it have to be tested on? This time it was
             | Salmon in puget sound, but next time it could be geese in
             | Alberta, or lizards in Argentina. It just seems like too
             | big of a problem space.
        
               | throwaheyy wrote:
               | The mode of transfer is urban stormwater runoff. Proving
               | the replacement chemical is safe for the salmon is good
               | enough.
        
         | ars wrote:
         | It's probably too early since this just came out.
         | 
         | But I suspect they can find an alternative to 6ppd and we just
         | need a bit of publicity, and then maybe a year to reformulate
         | tires.
        
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