[HN Gopher] Trials begin on lozenge that rebuilds tooth enamel
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       Trials begin on lozenge that rebuilds tooth enamel
        
       Author : beefman
       Score  : 64 points
       Date   : 2021-05-29 22:15 UTC (45 minutes ago)
        
 (HTM) web link (dental.washington.edu)
 (TXT) w3m dump (dental.washington.edu)
        
       | Tempest1981 wrote:
       | > The lozenge produces new enamel that is whiter than what tooth-
       | whitening strips or gels produce.
       | 
       | I wonder how white?
       | 
       | I'm a bit nervous about having those over-whitened glow-in-the-
       | dark teeth, that you sometimes see. Memories of that _Friends_
       | episode, too.
        
         | [deleted]
        
         | bamboozled wrote:
         | Who are you talking to ?
        
         | redisman wrote:
         | My coffee habit will make short work of any overly white teeth.
        
       | endisneigh wrote:
       | Assuming this works, isn't this pretty much game over for
       | dentists? I'm aware that dentists do more than fillings, but it
       | seems like there would be a serious contraction, even if this
       | costed something like $1000 a tooth after insurance.
       | 
       | That being said, even if this worked, it's not like it's instant,
       | so you still have to be careful with your teeth. I wonder how
       | this differs from novamin, which supposedly does the same thing
       | and you can already purchase now.
        
         | johnkpaul wrote:
         | Hah I felt this same way when I discovered you can change your
         | diet to basically completely remove all dental problems. I
         | doubt society can possible change quickly enough for us to see
         | the downfall of the profession.
        
           | killermouse0 wrote:
           | Would you care to elaborate on those diet changes?
        
             | wyager wrote:
             | Eliminate things bacteria can efficiently metabolize,
             | consume things that humans can efficiently metabolize.
             | Namely, eliminate saccharides (sugar, plant starches, etc.)
             | and get your calories from fat instead. Improved dentition
             | is only one of many benefits.
        
           | joshuahughes wrote:
           | Presumably no sugar being the primary factor. No carbs too?
        
             | sitzkrieg wrote:
             | sugar doesn't cause cavities, acids do. some bacteria which
             | is not uniformly present in people eats carbs and deposits
             | acids. this is covered in great detail ina good book, "kiss
             | your dentist goodbye" that i just read. ive seen
             | improvements in my awful teeth after giving the free
             | regimen a try
        
             | johnkpaul wrote:
             | Yeah, extreme no sugar and no carb, almost pure carnivore.
             | Haven't had a bit of tooth decay since.
        
             | Applejinx wrote:
             | Also, presumably, drink water. That can't hurt.
        
             | kaybe wrote:
             | I have a friend with extreme food restrictions, they can
             | mostly only eat animal products (plus white rice and very
             | few other things). They also cannot brush their teeth
             | regularly due to disability - yet their teeth look
             | fantastic!
        
               | johnkpaul wrote:
               | Yup this is me
        
             | sebmellen wrote:
             | Xylitol rinses are great too. Xylitol seems to function as
             | a sort of "probiotic" for the mouth.
        
               | sithadmin wrote:
               | It's sort of the opposite of a probiotic. In many
               | organisms, including many non-human mammals, it short-
               | circuits normal metabolic processes. Xylitol-sweetened
               | products will easily sicken, and frequently kill cats and
               | dogs, for instance.
        
               | sebmellen wrote:
               | Yes, you're right, it's more of an antibiotic, but it
               | seems to have a balancing effect on the oral microbiome.
               | 
               | The research is still nascent and inconclusive, though.
               | Here's an interesting study:
               | https://pubmed.ncbi.nlm.nih.gov/17263856/.
        
             | hungryforcodes wrote:
             | When I was two years old -- apparently, I only heard it
             | from the obvious source -- my mother went to a doctor and
             | asked when she could start giving me candy. I'm dating
             | myself but this was before 1990. Anyways, he said, "Never!
             | Never give him candy. He'll develop a sweet tooth and it's
             | game over for his teeth!".
             | 
             | Again paraphrasing and dramatizing, but you get the idea.
             | 
             | So my mom never gave me anything with sugar. To this day I
             | don't eat any sweets and I have no cavities or tooth
             | problems. I eat ice cream once a year, and mostly because
             | people seem to like shaming me for not liking it. I always
             | just have a couple of bites.
             | 
             | From the age of 5 to 10 I grew up on a boat in the
             | Caribbean and South and Central America, and can't remember
             | brushing my teeth once. It sounds weird I know. I brush
             | once or twice a day now.
             | 
             | Anyways my teeth are in great shape.
        
           | Blammar wrote:
           | This is from memory, so could be wrong.
           | 
           | The goal is to starve the streptococcus mutans bacteria in
           | your mouth. Since that lives off sugar and starch, you both
           | (a) rinse your mouth with a bactericidal (b) brush teeth,
           | tongue, and gums after ingesting any sugar or starch.
           | 
           | The downside is excessive bactericidal use or brushing can
           | damage your mouth tissues and teeth.
           | 
           | Another approach I had heard about but have no further info
           | was to be vaccinated against S. mutans, so presumably your
           | saliva would attack it somehow. I don't understand the
           | mechanism here.
           | 
           | In the meantime, I use a prescription dose of fluoride
           | toothpaste daily to harden the hydroxyapatite in my mouth.
        
             | johnkpaul wrote:
             | :-) my approach is just to not eat any sugar or starch but
             | definitely agree with mechanism.
        
             | wyager wrote:
             | You can also just quit eating saccharides. Incidentally (or
             | perhaps not), this has a lot of positive effects besides
             | improving dental health. It's a first line treatment for
             | many metabolic disorders like diabetes and even many cases
             | of epilepsy. It resolves many digestive issues, as it
             | reduces or eliminates most things humans can't easily
             | metabolize (plant fiber, large sugar molecules, etc.). It
             | helps with weight management because most human groups have
             | not yet evolved an appropriately tuned satiety response to
             | saccharides.
        
         | PragmaticPulp wrote:
         | Unfortunately, no. These only deposit a couple micrometers of
         | enamel per day if used twice daily. They could potentially help
         | as a form of preventative maintenance, but reversing
         | significant dental cavities seems unlikely.
        
           | endisneigh wrote:
           | That seems like a lot though. Let's say it's just 1
           | micrometer per day. A tooth is about 10mm (10,000
           | micrometers). So over a period of about 28 years all of your
           | teeth's enamel can be completely restored?
           | 
           | Given that most people don't lose all of the enamel of any of
           | their teeth it seems like there wouldn't be any point of
           | going to a dentist. By the time you're getting the age where
           | you'd even think about dentures, this treatment would
           | completely reverse all tooth decay no?
        
             | kaybe wrote:
             | I feel problems with gums and other areas don't get
             | stressed enough in childhood. There are plenty of other
             | problems that are not enamel-related, and I'd guess you can
             | easily still have trouble with enamel even with this
             | treatment.
        
             | saurik wrote:
             | Tooth decay isn't a generic slow wearing down of all of
             | your enamel but instead a concentrated attack on a small
             | location of enamel from food for example being consistently
             | stuck in a small fissure. A big thing you use dentists for
             | is managing plaque that makes these issues worse, and
             | probably also will help block the effects of these
             | lozenges. Polishing your teeth actually _removes_ small
             | quantities of enamel with the goal of making the teeth a
             | bit smoother so there are less places for things to get
             | stuck. Dentists also are dealing with issues where your
             | teeth get cracked or otherwise damaged from grinding or
             | hard foods. I can 't imagine just indiscriminately throwing
             | layers of enamel at the problem is going to leave you in a
             | solve where "there wouldn't be any point of going to a
             | dentist".
        
       | danschumann wrote:
       | Will this help Mitch Hedberg enthusiasts realize his dream of
       | having just two long curvy teeth?
        
       | Hamuko wrote:
       | > _In addition, the researchers are investigating a gel or
       | solution with the engineered peptide to treat hypersensitive
       | teeth. This problem results from weakness in the enamel that
       | makes the underlying dentin and nerves more vulnerable to heat or
       | cold. Most common products currently on the market can put a
       | layer of organic material on the tooth and numb nerve endings
       | with potassium nitrate, but the relief is only temporary. The
       | peptide, however, addresses the problem permanently at its source
       | by strengthening the enamel._
       | 
       | I want this so badly.
       | 
       | I've never had a cavity despite my poor dental hygiene habits and
       | lack of dental practice visits but apparently I suffer from
       | bruxism that can make half of my teeth hurt whenever I bite on
       | anything harder than a wet noodle. Just now I brushed my teeth
       | with a pain-numbing toothpaste and just the act of brushing my
       | teeth made them hurt. Although sometimes I can go for some time
       | without pain, it's been pretty much a constant in my life for the
       | last years.
        
       | Black101 wrote:
       | Please get those crooked dentists out of work, as much as
       | possible.
        
         | rubyist5eva wrote:
         | Let me guess..dentists should provide their valuable services
         | free of charge because...?
        
         | VierScar wrote:
         | Crooked dentists? Is this some sort of conspiracy theory?
         | Dentists are medical professionals, who have been needed since
         | the dark ages, and nowadays have very complex equipment and
         | technology to ensure the best long-term and life-like suitable
         | treatments for people.
         | 
         | What are you on about?
        
           | 542458 wrote:
           | To be fair, dentists do engage in what really looks like
           | price fixing (at least where I am, and to an outside eye).
           | Every dentist here charges the exact same amount, regardless
           | of whether they're in the middle of a high-income
           | metropolitan area or in bumkinville.
           | 
           | Also every once in a while you see some real horror stories
           | of dentists doing unnecessary procedures on sedated patients,
           | and although the extreme cases are absolutely the exception,
           | I always do have to wonder if I actually need the (often
           | expensive) treatments they recommend.
        
           | bpodgursky wrote:
           | Ehhh... dentists (even the not-obvious-scam ones) are
           | notorious for overprescribing expensive and invasive
           | unnecessary treatments.
           | 
           | They are medical professionals of course, and few are
           | recommending completely nonsense, but it's like, if go to a
           | plastic surgeon... they are probably going to find plastic
           | surgery to perform. Not that it's _wrong_, just that it's
           | really not necessary when you balance in the cost.
        
           | miles wrote:
           | > Crooked dentists? ... What are you on about?
           | 
           | Like any profession, dentistry has it share of charlatans:
           | 
           | The Truth About Dentistry
           | https://www.theatlantic.com/magazine/archive/2019/05/the-
           | tro...
        
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       (page generated 2021-05-29 23:00 UTC)