[HN Gopher] Scientist finds early virus sequences that had been ...
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       Scientist finds early virus sequences that had been mysteriously
       deleted
        
       Author : gumby
       Score  : 118 points
       Date   : 2021-06-23 20:32 UTC (2 hours ago)
        
 (HTM) web link (www.nytimes.com)
 (TXT) w3m dump (www.nytimes.com)
        
       | Bayesian_bro wrote:
       | I don't see good enough evidence to show the zoological origin
       | yet. I don't see good enough evidence of a lab leak origin yet
       | either. I do see good enough evidence for a Chinese coverup. I
       | can say for 100% certainly the Chinese are not being upfront with
       | their data. What scenario would hiding data benefit? Cui bono?
        
         | SV_BubbleTime wrote:
         | I think China is the only major country to grow their GDP for
         | 2020. Does that answer your question sufficiently?
        
         | AdamN wrote:
         | They might just want to protect other secrets about the lab and
         | keep everyone at arms length.
         | 
         | My bet is that even in China (which is not monolithic)
         | different stakeholders are not so sure and there's major CYA
         | between the scientists, the local managers, the Beijing-based
         | leadership, senior leadership at all levels. Nothing good can
         | come for any of these people if they allow the investigation to
         | proceed smoothly. What if it's discovered that some totally
         | unrelated incident happened years ago or that somebody was
         | embezzling or did shady land deals with Wuhan lab accounts? The
         | truth only helps people who are not involved. Everybody
         | involved is best served by keeping their mouth shut and
         | blocking any investigation.
        
           | plank_time wrote:
           | Sorry but China is about as monolithic as you can get. The
           | CCP had an incredibly tight control over the entire country.
           | It doesn't allow anything except for a monolithic view.
        
       | S_A_P wrote:
       | Can someone explain in non charged terms why its 'bad' to
       | investigate and or ask the right questions regarding whether or
       | not the virus was leaked from the Wuhan lab? Im genuinely curious
       | here. Thinking hypothetically here, _if_ it were leaked wouldnt
       | we all want to do a post mortem and figure out how to prevent it
       | from happening again?
        
         | Splendor wrote:
         | This is a charged topic, but I'll try to answer objectively
         | without trying to argue whether the reasons are good or bad.
         | 
         | I can think of two reasonable reasons why someone wouldn't want
         | to investigate the matter:
         | 
         | 1. It would be embarrassing for China.
         | 
         | 2. It may be hard to properly communicate or convince people of
         | the difference between an accidental lab leak vs. an
         | intentional lab leak which could add fuel to a fire of
         | jingoism/nationalism in other countries.
         | 
         | Again, I'm trying hard not to make a judgement here. Hopefully
         | I did a decent job.
        
           | fairpoints777 wrote:
           | It's not your problem if people take it the wrong way, points
           | are valid, you don't need to dedicate half your message to
           | disclaimers to appease the hyperoffended crowd - what should
           | I get upset about today people
        
         | Leary wrote:
         | Strawman. Nobody, even China, argues it's bad to investigate.
         | Everyone just wants the investigation to be free from political
         | interference.
        
         | justinpombrio wrote:
         | If it leaked from the lab, preventing that is very easy. We
         | just need to _stop doing gain of function research_.
         | 
         | Whether or not Covid came from a lab, it's at least plausible
         | that it did, and a virus just as bad could get accidentally
         | released in the future. So our options are:
         | 
         | - Continue gain of function research, and risk killing
         | literally millions of people
         | 
         | - Stop gain of function research, and lose any knowledge we
         | would gain from it.
         | 
         | Honestly, I don't know the first thing about gain of function
         | research, but that's one _hell_ of a risk we 're taking with
         | it. Can we maybe not try to make the viruses deadlier?
        
           | notJim wrote:
           | Is it a certainty that the lab was doing gain of function
           | research? Haven't followed this closely.
        
             | lamontcg wrote:
             | There's no indication WIV was doing any gain of function
             | research.
             | 
             | WIV did collaborate with UNC Chapel Hill to do GOF research
             | in America, in mice using a SARS-CoV-1 backbone.
             | 
             | The US government send funds to WIV to study SADS-CoV in
             | pigs.
             | 
             | Circular logic is invoked to "prove" that those funds led
             | to secret GoF research which has never been published or
             | talked about on the basis that the pandemic arising in
             | Wuhan is too much of a coincidence (and coincidences
             | logically can never happen).
        
         | AdamN wrote:
         | Some/many people can't separate the accusation from it being
         | shown to be true. During that period of time (years??), it's a
         | distraction for those people from the other problems like
         | handling vaccine distribution, relations with China independent
         | of COVID19, etc...
         | 
         | Yes, if this were a narrow academic research project looking
         | into the origin that was left de-politicized until there was an
         | outcome that would be great. Unfortunately this whole thing was
         | born political and China hasn't done itself any favors by
         | always being so hush hush.
        
         | soperj wrote:
         | It's not bad, it's just the reason people are doing it have
         | nothing to do with preventing it form happening again.
        
         | FriendlyNormie wrote:
         | The fucking fact that you felt the need to even ask this. Jesus
         | christ.
        
         | legostormtroopr wrote:
         | There are only 2 reasons I can think of:
         | 
         | 1. Because Trump called for an investigation into the Lab Leak
         | Theory. Since Trump is bad, everything he says and does is
         | always bad. This meant that everyone who was anti-Trump said
         | that the lab leak theory was 100% false, definitely a
         | consipracy theory and hence.... _bad_.
         | 
         | 2. Because the Chinese government have used the modern
         | political environment to deflect all critism as racism. Because
         | people often shorten "Chinese Government" to "China" in news
         | (much like the US), they take it that attacks against "China"
         | aren't really attacks against the country but instead racist
         | attacks against the people. Since racism is bad, criticism of
         | China is racism, and investigating the Lab Leak leak is
         | criticism of China - it stans to reason that the Lab Leak
         | theory is racism, and hence.... _bad_.
        
           | fairpoints777 wrote:
           | Well reasoned points, not sure why you are getting downvoted,
           | probably the left/liberal censorship crew (my way of thinking
           | or the highway, insert random accusations of racism/sexism)
        
         | McTossOut wrote:
         | No, investigation or questions are probably merited given the
         | scale of this thing.
         | 
         | Random fragments of what sounds like an investigation getting
         | immediately published is the problem.
        
       | neonate wrote:
       | https://archive.is/kbqdB
        
       | femto113 wrote:
       | There's no obvious reason to believe this is nefarious or even
       | "mysterious". From the WaPo article[1] on the subject here's the
       | statement from the NIH (which maintains the database)
       | 
       | "These SARS-CoV-2 sequences were submitted for posting in SRA in
       | March 2020 and subsequently requested to be withdrawn by the
       | submitting investigator in June 2020. The requestor indicated the
       | sequence information had been updated, was being submitted to
       | another database, and wanted the data removed from SRA to avoid
       | version control issues"
       | 
       | [1] https://www.washingtonpost.com/health/coronavirus-origin-
       | nih...
        
       | pitched wrote:
       | https://www.printfriendly.com/p/g/hGqAvT
        
       | codeulike wrote:
       | Article is Paywalled but its basically about this twitter thread
       | from Bloom Labs:
       | 
       | https://twitter.com/jbloom_lab/status/1407445604029009923
       | 
       | This technical bit is interesting - although the data had been
       | 'deleted' from the Sequence Read Archive* web app by the original
       | submitter, this tweet explains that they were able to recover the
       | data via storage.googleapis.com:
       | 
       | https://twitter.com/jbloom_lab/status/1407445615248691201
       | 
       |  _I discovered that even though the files were deleted from
       | archive itself, they could be recovered from the Google Cloud at
       | links likehttps://storage.googleapis.com/nih-sequence-read-
       | archive/run... (5/n) ..._
       | 
       | So technical question for HNers - what lives at
       | storage.googleapis.com usually? Was that like a cloud mirror or
       | was it more like the 'delete' function in the web app was only
       | removing things from the index but leaving the deleted stuff
       | accessible?
       | 
       | * Sequence Read Archive seems to live at
       | https://www.ncbi.nlm.nih.gov/sra
        
         | colechristensen wrote:
         | They were supposedly storing artifacts publicly available on
         | GCP's object store, an efficient way to do things for
         | distribution of non-secure large pieces of data.
         | 
         | "delete" deleted the reference to these objects but the objects
         | were kept around. (This is a not-so-bad practice, if you're
         | hacked and somebody tries to wipe everything, or some bug or
         | fat finger deletes everything, you've deleted references to
         | data not actual data)
        
         | ve55 wrote:
         | Most likely the latter: the server-side code in charge of
         | deleting data did not make a call to their storage api to also
         | remove the object itself. There's a good chance that is
         | intentional and serves as a soft-deletion function, such that
         | it could be reverted (or the data otherwise used) if needed.
        
           | pitched wrote:
           | That was my read on this too and Dr. Bloom accidentally
           | hacked the NIH. The next question though is whether they'll
           | change this or not? Is the guarantee that anyone can retract
           | at any time important enough to make the db useful? Will the
           | Chinese government mandate no one there ever use it again
           | now?
        
             | nitrogen wrote:
             | _Dr. Bloom accidentally hacked the NIH._
             | 
             | In case this is why this comment was downvoted, it's worth
             | remembering that others have been charged with CFAA
             | violation for basically the same thing.
        
       | bgentry wrote:
       | There was some prior discussion on this submission from
       | yesterday, though it fell just short of the front page:
       | https://news.ycombinator.com/item?id=27598222
       | 
       | The source paper
       | (https://www.biorxiv.org/content/10.1101/2021.06.18.449051v1) or
       | Twitter thread
       | (https://twitter.com/jbloom_lab/status/1407445604029009923) are
       | probably better sources than the New York Times article based on
       | them.
        
       | bigpumpkin wrote:
       | "Dr. Goldstein noted that the testing paper listed the individual
       | mutations the Wuhan researchers found in their tests. Although
       | the full sequences are no longer in the archive, the key
       | information has been public for over a year, he said."
        
         | wallacoloo wrote:
         | Not to mention it was deleted in June 2020. I have to imagine
         | many researchers had already downloaded the data by then and
         | that there are a number of local copies that could be shared
         | out if there was compelling reason to do so.
         | 
         | If it was a coverup it was a rather poor one. It's hard for me
         | to think this was nefarious, unless the intention was just to
         | delay (in a plausibly deniable manner).
        
           | mrkstu wrote:
           | It isn't, by itself, conclusive at all, but the amount of
           | smoke China generates around this whole thing, vs
           | transparency, screams that there is fire in the middle of the
           | smoke.
        
             | SketchySeaBeast wrote:
             | Is this amount of smoke uncharacteristic for China?
        
               | tux3 wrote:
               | Establishing a pattern of shiftiness would not make the
               | actions in question less questionnable.
               | 
               | If I hear a surprising claim from a pathological liar,
               | I'm also less likely to believe it, not more!
        
               | joejerryronnie wrote:
               | No, but neither is fire
        
       | 0-_-0 wrote:
       | If I remember correctly, the disappearance of these sequences was
       | discussed more than a year ago in Bret Weinstein's podcast, among
       | many other indicators of a lab leak:
       | 
       | https://youtu.be/q5SRrsr-Iug?t=1843
       | 
       | He's been the canary in the coal mine on numerous issues
       | surrounding COVID.
       | 
       | edit: listen from 30:43, also from 25:11:
       | https://youtu.be/q5SRrsr-Iug?t=1511
        
         | cma wrote:
         | >He's been the canary in the coal mine on numerous issues
         | surrounding COVID.
         | 
         | He's also been the carbon monoxide in the coal mine, steering
         | people away from vaccines
        
           | eloff wrote:
           | Yeah, I don't agree with this assessment of the risks there.
           | 
           | The more people that are vaccinated, the shakier his argument
           | becomes.
           | 
           | Covid19 has very real, well documented risks. The common
           | vaccines have very low known risks by comparison. The space
           | for unknown risks shrinks by the day.
           | 
           | That's the danger inherit with being a contrarian. Mostly you
           | end up being wrong. It's a very important role though, to
           | challenge accepted beliefs and create a dialog around them.
        
           | DiffEq wrote:
           | Not all vaccines are created equal.
        
             | peter4123 wrote:
             | Great point - The COVID19 Vaccines, particularly the mRNA
             | ones are some of the best ever made, ~90% effective at
             | preventing disease and ~100% effective at preventing death.
        
         | xyzzy123 wrote:
         | You're thinking of the WIV database that was offlined 12
         | September.
         | 
         | This is new. We don't know why the sequence was deleted; the
         | submitter cited "version control" reasons (data was being
         | submitted somewhere else) but then deleted both known copies.
        
         | lamontcg wrote:
         | > among many other indicators of a lab leak:
         | 
         | literally nothing in this article or in the sequences is
         | indication of a lab leak.
         | 
         | it isn't even particularly clear there is any cover up here,
         | particularly since an article on the sequences was published.
         | 
         | if there's any deliberate suppression it would seem to be to
         | hide the fact that scientists were studying the virus sooner
         | than previously admitted and that they should have raised the
         | alarm earlier.
        
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       (page generated 2021-06-23 23:00 UTC)