[HN Gopher] The Grayness of the Origin of Life
       ___________________________________________________________________
        
       The Grayness of the Origin of Life
        
       Author : Breadmaker
       Score  : 35 points
       Date   : 2021-07-23 20:00 UTC (3 hours ago)
        
 (HTM) web link (www.mdpi.com)
 (TXT) w3m dump (www.mdpi.com)
        
       | NotSwift wrote:
       | A nice article. It seems likely that we will never really know
       | how life started.
       | 
       | It is still very interesting to research this subject, because it
       | might help us to learn more about the possibility of life on
       | other planets.
        
         | ExpiredLink wrote:
         | From a scientific point of view we can - not just will - never
         | know the origin of life. Of course, popular science frames it
         | differently.
        
           | mypalmike wrote:
           | What makes it fundamentally impossible to know the origin of
           | life? It seems we are likely to develop and refine
           | experiments and theories that approximate the initial
           | conditions and processes by which life took hold. Some of the
           | details of how it happened are certainly lost to time, but it
           | seems there's a lot of room for exploration towards a fairly
           | valid model.
        
         | Koshkin wrote:
         | > _we will never really know how life started_
         | 
         | A big bang of another sort.
        
         | AprilArcus wrote:
         | I think in our lifetimes, we'll know enough about the
         | preconditions for abiogenesis to perform experiments
         | replicating portions of the process in vitro.
        
       | aazaa wrote:
       | > A more inclusive representation is to recognize a spectrum
       | between the non-living and the living--a "grayness" resulting
       | from the protracted evolutionary process that gave rise to life.
       | 
       | The meaning of "grayness" would appear to have something to do
       | with the fuzzy line between life and non-life.
       | 
       | There is a footnote to the article "The Seven Pillars of Life":
       | 
       | https://www.pps.net/cms/lib/OR01913224/Centricity/Domain/333...
       | 
       | But it doesn't mention grayness at all.
       | 
       | This gets cleared up a little a few paragraphs in:
       | 
       | > The ability to clearly distinguish between abiotic and biotic
       | systems is considered by many a prerequisite for effective
       | astrobiology studies. However, since no natural demarcation truly
       | exists, there is a profound difficulty in advancing the field if
       | we rely on a strict dichotomy. ...
        
       | antattack wrote:
       | Motor proteins look alive:
       | 
       | https://www.youtube.com/watch?v=y-uuk4Pr2i8
        
         | Koshkin wrote:
         | As do these:
         | 
         | https://www.youtube.com/watch?v=hsLJdpjSJcM&t=15s
        
         | AprilArcus wrote:
         | I love this animation because it's beautiful, but I hate that
         | it gives the impression of deliberate one-foot-in-front-of-the-
         | other movement. In reality, when the "foot" of the motor
         | protein is unbound, it is oscillating to and fro in a state of
         | brownian motion until it happens to snap into place at the next
         | (or, infrequently but inevitably, the previous) subunit. At
         | this scale, quantum effects such as tunneling come into play,
         | and it would be cool to visualize the organized thermodynamic
         | chaos of the cell rather than the mechanical operation of a
         | homunculus.
        
       | macawfish wrote:
       | I'm personally convinced at this point that most everyday
       | distinctions between living and dead are arbitrary human
       | categorizations. Even a "dead body" is teaming with life. As far
       | as "inanimate matter" is concerned, all matter is ultimately part
       | of a plethora of various different cycles and processes of
       | transformation and recapitulation... even if something
       | temporarily looks like it's static to us and our meager little
       | narrow timeframe of experience, it's not.
       | 
       | Just to clarify, I don't mean that these distinctions are
       | meaningless, just that their meaning is inherently embedded in
       | human experience.
        
         | slibhb wrote:
         | > Just to clarify, I don't mean that these distinctions are
         | meaningless, just that their meaning is inherently embedded in
         | human experience.
         | 
         | In that case, describing the distinction as "arbitrary" seems
         | wrong.
        
         | shrimpx wrote:
         | Why not go further and say the entirety of "our reality" is a
         | human hallucination, as our senses are limited and our brains
         | peculiar in how they process their inputs. That the "real
         | reality" is an imperceptible-to-us dance of fields (even that
         | is only as far as our theories take us).
        
         | [deleted]
        
         | jollybean wrote:
         | That's a good thought - but worth considering that just because
         | lines are fuzzy doesn't make them either 'arbitrary' or even
         | 'subjective'.
         | 
         | That a materialist perspective gives us some nice hard rules
         | for understanding certain things, it also by definition
         | struggles to help us understand the nature of other things,
         | i.e. 'most important bit' which is 'life' itself, so maybe we
         | should be thinking about that problem a little bit differently.
         | 'Emergence' seems to be a least one idea, among many.
        
           | guerrilla wrote:
           | > That's a good thought - but worth considering that just
           | because lines are fuzzy doesn't make them either 'arbitrary'
           | or even 'subjective'.
           | 
           | Interesting and plausible, but you didn't give an argument or
           | any example for that.
        
             | jollybean wrote:
             | For most things in the real life that we categorize, the
             | rules that distinguish those categories can be vague. It
             | doesn't mean those categories are not valid, or a function
             | of 'human perception'.
             | 
             | We have difficulty with biological distinction, but we can
             | still confidently categorize something as being a 'Horse'
             | and 'Not A Horse' ... even if sometimes it's a little bit
             | ambiguous, aka 'Kind of a Horse'.
             | 
             | Edit: and as for 'other ways of thinking' it very quickly
             | goes into metaphysics so it's hard to talk about because we
             | don't spend much time in that realm. 'Emergence' and
             | 'Biocentrism' are interesting ideas (fields?) that sit
             | within more or less regular bounds of science and so
             | they're just examples of what I'm referring to.
        
         | TaupeRanger wrote:
         | I think it's simpler than you're allowing. Death in animals is
         | the absence of consciousness with no possibility of recovery.
         | In plants and maybe-but-probably-not-sentient life, it's more
         | complicated.
        
           | gus_massa wrote:
           | We all agree when we should say that a cow is dead, but what
           | about sponges? You can pass a sponge through a sieve, and the
           | isolated cells will recombine
           | https://www.shapeoflife.org/video/sponges-time-lapse-
           | sponge-... (Is there a better link?) Can a single cell of a
           | sponge create a "new" sponge? Or it's just the "old" sponge?
           | Should you wait until the last cell is dead until we can
           | claim it's dead?
           | 
           | Back to cows...
           | 
           | You can remove the heart of a cow and keep the heart alive in
           | a proper device, and keep the rest of the cow alive with an
           | artificial heart. (I don't know if someone has tried this
           | with cows, but this should be possible with the same
           | technology for hearts transplants in humans.)
           | 
           | Are both parts alive? What happens if I unplug one of them?
           | Is the heart-less-cow is the real cow? I think we all agree
           | about this last question, but from the cellular level it's
           | just an arbitrary classification, in spite it's useful for
           | us.
        
             | mysterydip wrote:
             | My favorite example of this is the planarian. You can cut
             | its head in half and it will generate two new halves. Same
             | with the tail. Or cut the whole thing into pieces, and each
             | piece will regenerate the whole body.
        
           | [deleted]
        
       | xor99 wrote:
       | So interesting! Some similar work on this area:
       | 
       | https://www.nature.com/articles/s41467-021-23258-x
       | 
       | https://ui.adsabs.harvard.edu/abs/2020AGUFMP001...01C/abstra...
        
       ___________________________________________________________________
       (page generated 2021-07-23 23:00 UTC)