[HN Gopher] Philippine ethnic group has most Denisovan DNA
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       Philippine ethnic group has most Denisovan DNA
        
       Author : DocFeind
       Score  : 141 points
       Date   : 2021-08-14 16:25 UTC (6 hours ago)
        
 (HTM) web link (www.uu.se)
 (TXT) w3m dump (www.uu.se)
        
       | codezero wrote:
       | Interesting tidbits from the paper[0]:
       | 
       | Negritos diverged from Papuans 53kya!
       | 
       | They estimate the East Asian influx as being only about 2200ya!
       | 
       | Wild to imagine what pressures caused those two events.
       | 
       | [0] https://www.cell.com/current-
       | biology/fulltext/S0960-9822(21)...
        
         | pcrh wrote:
         | From that report it seems that the level of Denisovan DNA in
         | modern Aya Magbukon is just under 4% (fig 3D), if I have
         | understood it correctly. Otherwise they are about 90%
         | Australasian, with 10-15% East Asian (Fig 1D).
         | 
         | So there was quite a bit of displacement of Denisovans, with
         | some interbreeding.
        
       | WolfCop wrote:
       | Does anyone know of good books or other resources to teach kids
       | (7-10 years old) about the evolution of humans? Things like
       | different homo species, how they are related, evidence that has
       | been found, etc.
        
         | jhart99 wrote:
         | I remember a really good issue of national geographic that I
         | read as a kid that talked all about this. Level is a bit higher
         | but they showed how they have found evidence through bones and
         | dated them in different ways and how they reconstructed
         | different parts of the evolution to modern Homo sapiens.
        
           | selimthegrim wrote:
           | Any idea on the timeframe of publication?
        
         | mistrial9 wrote:
         | the stories have really changed in the last ten to twelve years
         | with DNA evidence; so much that one 'recent' book may not be in
         | sync with another
        
           | cpu_qwerty wrote:
           | In terms of books, I'd say Reich's "Who We Are and How We Got
           | Here" is still the best popular intro available.
        
         | cmrdporcupine wrote:
         | My kids enjoyed this series, which is sort of a mixture of fun
         | and facts about Neanderthals, it's very silly and fun:
         | 
         | https://www.penguinrandomhouse.com/series/LNE/lucy-and-andy-...
         | 
         | When they were younger, we read the kids this:
         | 
         | https://www.amazon.ca/Our-Family-Tree-Evolution-Story/dp/015...
         | 
         | This is also a good one we have which covers evolution more in
         | depth:
         | 
         | https://www.amazon.ca/Evolution-Story-Earth-Jay-Hosler/dp/08...
         | 
         | There appear to be some others out there now that didn't exist
         | when my kids were younger. This one looks good:
         | 
         | https://www.amazon.ca/Sapiens-Graphic-History-Birth-Humankin...
        
         | oofabz wrote:
         | I recommend CARTA, the Center for Academic Research & Training
         | in Anthropogeny. They have many academic lectures on human
         | evolution on their website. In particular, check the "Past
         | Symposia" section.
         | 
         | https://carta.anthropogeny.org/
        
       | diego_moita wrote:
       | For those interested in genetic analysis of human evolution I
       | highly recommend David Reich - Who We Are and How We Got Here.
       | 
       | It is really a fantastic book.
        
         | 08-15 wrote:
         | For those who think David Reich is a scientist, I recommend
         | "Genetic evidence for complex speciation of humans and
         | chimpanzees", John Wakeley's reply "Complex speciation of
         | humans and chimpanzees" and "Patterson et al. reply" to
         | Wakeley's reply. (All published in Nature in 2006, 2008, 2008,
         | respectively.)
         | 
         | It's a fantastic demonstration of modern science at work.
        
       | jmpman wrote:
       | My buddy's grandparents are from that group. Someone's getting
       | some old Geico commercial YouTube links.
        
       | ryan_j_naughton wrote:
       | The article doesn't mention the percentages, which is
       | disappointing
        
         | ImaCake wrote:
         | The published academic article seems to estimate an upper bound
         | of about 4%, but I might be interpreting that wrong. It is
         | worth noting that the information is here based on single
         | nucleotide variants which don't tell us _everything_ about the
         | genome, but a convenient proxy for most of it.
        
         | jhart99 wrote:
         | They give confidence intervals in the text for about 51 MB(mega
         | bases) which would be about 2 percent or so if that was across
         | the whole mappable genome. Just a note that does not translate
         | to 2% different genes or something, but rather that specific
         | mutations they know can be traced back to a specific
         | population. Most would have no effect.
        
         | codezero wrote:
         | It's hard to sus an absolute percent but my best guess from
         | some figures is 5% but I could be way way off.
        
         | jacobsievers wrote:
         | From the article: "Compared with Australians and Papuans, the
         | Negritos' Denisovan ancestry was up to 46 per cent higher..."
        
           | Fordec wrote:
           | 46 percent higher than what? Do Australians have 0% of total?
           | 50% of total?
        
             | DoingIsLearning wrote:
             | > Denisovans apparently interbred with modern humans, with
             | about 3-5% of the DNA of Melanesians and Aboriginal
             | Australians and around 7-8% in Papuans deriving from
             | Denisovans. [0]
             | 
             | [0] https://en.m.wikipedia.org/wiki/Denisovan
        
               | im3w1l wrote:
               | Do they have the same 7-8%? Or one piece of the puzzle
               | each?
        
           | sandworm101 wrote:
           | 46% higher, but what total percentage of DNA is Denisovan?
        
       | ummonk wrote:
       | The notable thing is that there was never a land bridge to the
       | Philippines, so the denisovans would have swum or most likely
       | traveled by canoe to the Philippines.
        
         | StreamBright wrote:
         | Or we miss crucial details about our history.
        
         | throwawaycities wrote:
         | History provides plenty of examples of humans transporting
         | other humans and other species across seas against their will.
        
           | dmoy wrote:
           | Note that larger oceangoing ships were not invented until
           | about 25,000+ years later.
           | 
           | Transporting humans against their will is a non-sequitur when
           | considering the mode of transit. It would be canoes, rafts,
           | or swimming. Whether voluntarily or not.
        
             | newsclues wrote:
             | I'm pretty sure I tied up another kid and transported them
             | to an island as a child at summer camp in the 90s.
             | 
             | It's possible.
        
             | throwawaycities wrote:
             | As I said there are plenty of examples in history of
             | transporting humans against their will, and yes those
             | historical examples include canoes and rafts.
             | 
             | I think it's much more probable there had to have been
             | complex social relationships between these groups rather
             | than the only possibility being that 1 species of prehumans
             | developed single person boats used to migrate to these
             | islands and then a second species of prehumans
             | independently developed boats that also held a maximum of 1
             | person and used them to migrate to the same islands already
             | inhabited by the 1 group, and then the 2 groups interbred
             | per the article.
        
           | chronic2703 wrote:
           | > History provides plenty of examples of humans transporting
           | other humans and other species across seas against their
           | will.
           | 
           | And looking at history, it seems this accelerated the
           | positive development and advancement of the human species.
        
         | 08-15 wrote:
         | It is far more notable that there is exactly one known
         | Denisovan fossil, namely the distal phalanx the whole
         | "Denisovan Genome" was sequenced from. One could argue that she
         | was just another Neanderthal, but that didn't do the vanity of
         | the authors of "Genetic history of an archaic hominin group
         | from Denisova Cave in Siberia" [Reich2010] justice.
         | 
         | Regarding the admixture, the analysis doesn't indicate the
         | direction. If a Denisovan had offspring with an ancestor of
         | present day Philippinos and the offspring stayed with the
         | humans, that would create exactly the same D-statistics as if
         | the child stayed with the Denisovans.
         | 
         | I think the most believable scenario is that humans migrated
         | through an area that was already inhabited by Neanderthals,
         | some of them had fun with the locals, and _the_ Denisovan is an
         | offspring of such a family. That 's much easier to believe than
         | Denisovans, who somehow never left traces in the fossil record,
         | living all over Asia and contributing genes to _all_ present
         | day Melanesians.
         | 
         | [Reich2010] has a single sentence to rule out this scenario:
         | the fossil is a tiny bit too old to be affected by the
         | migrating modern humans. That relies on stratigraphic dating
         | (C14 fails at around 50ka), and that relies on the assurance of
         | the archaeologists that "most of the site was disturbed, but
         | _this_ fossil is from the _undisturbed_ part! " Yeah, right.
         | 
         | As you said, Denisovans, assuming there was ever more than one,
         | and assuming they weren't just Neanderthals, probably swam to
         | the Philippines. Isn't it amazing how much we can learn from a
         | single pinky bone?
        
           | patall wrote:
           | But there are multiple known Denisovans by now, i.e
           | https://www.pnas.org/content/112/51/15696
           | 
           | There is even a known Neanderthal Denisovan hybrid:
           | https://www.nature.com/articles/d41586-018-06004-0
           | 
           | (Of course, that doesn't make it less amazing how much we can
           | learn from a single bone)
        
           | bugzz wrote:
           | We have plenty of Neanderthal genetic sequences. So seeing
           | even just one Denisovan sequence showing a large divergence
           | from all the other Neanderthal sequences is enough to
           | demonstrate a separate, distinct population.
        
             | 08-15 wrote:
             | How much is large?
             | 
             | The dendrogram is right here:
             | https://www.eva.mpg.de/genetics/genome-projects/neandertal/
             | 
             | The difference between the Denisovan and the Neanderthals
             | is bigger than between San and French, but not by much.
             | Keep in mind that the archaic genomes are noisy, and noise
             | adds to their distance.
             | 
             | At the time, the debate was whether Neanderthals and the
             | Denisovan constitute different species or just different
             | subspecies. (Taxonomy is fun. You get to name species you
             | discover after yourselves. I'd love to discover a new
             | species, but in a pinch, a subspecies will do.)
             | 
             | You use the meaningless term "population". Whatever, let
             | them be different populations. Now we have two populations,
             | namely the "Denisovan" and the "Altai Neanderthal" living
             | in the same cave, at roughly the same time.
        
         | legutierr wrote:
         | I would wager that the integration of the Denisovians with this
         | community's other ancestors happened in mainland Asia, long
         | before their decedents traveled to the Philippines.
        
           | kurthr wrote:
           | Yep, when you're looking at relatively low concentrations
           | that are constantly falling (each generation) then looking at
           | an island to find a higher concentration makes a lot of sense
           | long after concentrations were actually high.
        
           | ummonk wrote:
           | You're arguing for a founder effect explaining the higher
           | Denisovan proportion on the island vis a vis other parts of
           | southeast asia?
        
             | [deleted]
        
             | garbagetime wrote:
             | Are you implying that wouldn't make sense? Because it makes
             | sense to me.
        
               | ummonk wrote:
               | That was my first thought when I had seen news of the
               | paper, but the paper had some data to suggest the
               | negritos split off from other sapiens before the
               | denisovan introgression.
        
             | spoonjim wrote:
             | Makes sense. Denisovan descendants go to Philippines, the
             | ones left behind get killed off by some other land-based
             | group.
        
       | zozbot234 wrote:
       | This jives in interesting ways with Southeast Asian folklore,
       | which has held since time immemorial that semi-mythical divine
       | beings called "Lemurians" were the true ancestors of modern-day
       | humans, and the bringers of civilization and culture to that part
       | of the world. Could it be that ancient Denisovans were in fact
       | the Lemurians of popular lore?
        
         | tomjakubowski wrote:
         | I thought that Lemuria/Lemurians was a hypothesis developed by
         | Europeans in the 19th century. Wikipedia doesn't mention
         | anything about its presence in traditional folklore. Is there a
         | similar myth indigenous to Southeast Asia that you might have
         | mixed up with Lemuria?
         | 
         | https://en.wikipedia.org/wiki/Lemuria
        
         | vmh1928 wrote:
         | The Leprechauns of South East Asia. So what does that make the
         | Leprechauns of Ireland? A remnant of Denisovans that fled west?
        
         | prox wrote:
         | Lemurian is a theosophic invention afaik, so not really an
         | ancient myth.
        
         | screye wrote:
         | would be hilarious if Hanuman was a denisovan.
        
         | frutiger wrote:
         | Wouldn't it be the other way: Sapiens would be the semi-divine
         | beings bringing civilisation to the local Denisovans?
        
           | taylorfinley wrote:
           | That framing gets my anti-colonialist emotions stirring.
           | 
           | I guess it depends which myth you're more likely to subscribe
           | to, the 'white savior' or the 'noble savage' (please don't
           | mistake this post for advocating those tropes)
           | 
           | Edit: Getting downvoted to hell because people are so
           | sensitive and think I'm implying early homo sapiens were
           | light-skinned. That's silly and I probably should have just
           | not posted anything in a conversation like this where
           | everyone is looking to be offended. That said I'm leaving
           | this here for context.
        
             | pram wrote:
             | Maybe applying contemporary ideology to legendary
             | prehistory events that happened 30,000 years ago is boldly
             | moronic. Makes you think.
        
               | taylorfinley wrote:
               | Clearly I need to break this down in to very simple
               | terms, since people think they understand my post and
               | clearly don't and are labeling me 'bodly moronic' because
               | of their own misunderstanding.
               | 
               | One person speculated that a mythical story might be
               | evidenced by this finding, that the Denisovans might have
               | been the civilizing divines spoken of in legend. Another
               | person said, wouldn't it be the Sapiens that were divine?
               | I called out my own anti-colonial bias, recognizing that
               | my frame has me inclined to believe the first framing
               | ('denisovians were the divines in the legend'), and then
               | speculated that there's a spectrum of opinions one could
               | have and which group you label 'divine and civilizing'
               | and the other 'not-divine and un-civilized' depends on
               | your own biases.
               | 
               | But go on and downvote me and call me names because
               | you've misunderstood my point.
        
               | [deleted]
        
             | garmaine wrote:
             | You are getting down-voted because you are posting a knee-
             | jerk emotional response. The poster you are originally
             | replying to isn't making any kind of comparison to European
             | colonialism, you are. Then you are getting upset at your
             | own comparison. That is not productive.
             | 
             | For the record I interpreted the original post as saying
             | "the legend speaks of another race coming and bringing
             | civilization. Since the timeline is such that the
             | denisovans were there first and the sapians came after,
             | wouldn't it make more sense that this is a legend told by
             | the denisovans about sapians?"
        
               | wolverine876 wrote:
               | > you are posting a knee-jerk emotional response
               | 
               | You have no idea what their emotions are. Please don't go
               | there. If something doesn't make sense to you, just ask.
        
               | ertian wrote:
               | He explicitly says that the 'framing' gets his emotions
               | stirring.
        
             | inglor_cz wrote:
             | It is well possible that Sapiens were black and Denisovans
             | white.
        
             | frutiger wrote:
             | Yeah the Sapiens arriving into the Philippines were almost
             | certainly dark skinned. You might want to check your
             | biases.
        
               | [deleted]
        
               | taylorfinley wrote:
               | That's so blatantly obvious I didn't even think to
               | explain that I was attempting to draw a parallel between
               | homo sapiens thinking homo sapiens are the 'civilizing
               | force' and europeans thinking europeans are the
               | 'civilizing force'
               | 
               | Edit: for context, I am from Hawaii and as such deeply
               | interested in the Polynesian migrations. I have taken
               | anthropology courses on human migration patterns across
               | the Pacific. I would laugh at anyone who suggested the
               | early homo sapiens migrations were light-skinned.
        
               | decremental wrote:
               | I read threads like this and just think "I no longer have
               | any connection to this world."
        
               | [deleted]
        
               | thatguy0900 wrote:
               | More like we no longer have any connection with people
               | who spend too long getting polarized by the internet. Go
               | to the area in question and ask people their thoughts on
               | how their creation myths tie into sapians, denisovians,
               | and colonialization. I would assume you'd get alot of
               | confused stares.
        
               | s5300 wrote:
               | You're in a place with some of the most neurodivergent
               | people, often on the Autism/Asperger's spectrum (myself
               | included), who also feel the need to be dwelling/posting
               | on an online forum such as this.
               | 
               | That said, discussions will often get exceedingly hard to
               | understand or relate to, especially on any "normal"
               | emotional level...
               | 
               | Don't think anything going on here is much related to the
               | world we live in as a whole. It's like, a representation
               | well under 0.25%
               | 
               | Go outside, talk with normal people if you've had a
               | little bit much HN
        
           | tomjakubowski wrote:
           | No. The time Sapiens and Denisovans would have gotten
           | together was well before any humans had developed agriculture
           | or civilization. Neanderthals were also in the mix in
           | Southeast Asia.
        
       | ilamont wrote:
       | There's an interesting connection to Taiwan, which also ties into
       | early migration to more distant parts of Southeast Asia and
       | Australia:
       | 
       |  _Our current understanding is that after humans migrated out of
       | Africa, they flowed down through South East Asia, hopping across
       | narrow straights and between islands. From Timor, they used
       | rudimentary rafts or dugout canoes to cross to Papua New Guinea,
       | then headed down the scythed curve of the Bismarck Archipelago,
       | and reached the far edge of the Solomon Islands by around 40,000
       | years ago. There, nothing but the open ocean lay ahead of them,
       | and so these people - the Near Oceanians - stopped, and Remote
       | Oceania remained uninhabited.
       | 
       | Then some 5,000 years ago, a group of humans from what is now
       | Taiwan left their home shores and journeyed south through the
       | Philippines and Indonesia into Near Oceania. Called
       | Austronesians, they brought with them sophisticated maritime
       | technology and seafaring skills. They mixed with populations of
       | the Near Oceanians, forging a new people - the Lapita - who then
       | struck out to populate the rest of the Pacific. ...
       | 
       | "Our analyses suggest that humans left Taiwan more than 5,000
       | years ago, and that admixture between the Austronesian incomers
       | and the populations of Near Oceania started only 2,000 years
       | later," Patin says. "The expansions from Taiwan therefore took
       | some time, and may have involved a maturation phase in the
       | Philippines or Indonesia."_
       | 
       | https://cosmosmagazine.com/history/palaeontology/denisovan-d...
        
       | poisonarena wrote:
       | maybe thats why they are so nice
        
       | chalcolithic wrote:
       | What about other extinct human species? Are there similar
       | findings?
        
         | StreamBright wrote:
         | There are few interesting findings recently.
         | 
         | https://www.abc.net.au/news/science/2021-06-25/unusual-ancie...
        
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