[HN Gopher] Increased risk of traffic accidents in subjects with...
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       Increased risk of traffic accidents in subjects with latent
       toxoplasmosis (2002)
        
       Author : ansaso
       Score  : 78 points
       Date   : 2021-09-05 12:58 UTC (10 hours ago)
        
 (HTM) web link (www.ncbi.nlm.nih.gov)
 (TXT) w3m dump (www.ncbi.nlm.nih.gov)
        
       | throwthere wrote:
       | As interesting as this is, it's kind of got my spidy-sense
       | tingling. How many non-significant outcomes did test and not
       | publish before seeing traffic accidents? The perfect dose-
       | dependence gives more credence (increasing odds ratio at
       | increasing titers), although the sample size is small.
        
         | Pyramus wrote:
         | Yes, the dose-response is the interesting bit, and strong
         | indication for causation.
         | 
         | Not an expert so don't know how well we understand the
         | mechanism of action, which is crucial.
        
           | hn_throwaway_99 wrote:
           | The paper states high up that it's been well studied that
           | Toxoplasmosis infection increases reaction time - this study
           | was basically just showing that that laboratory-viewed metric
           | has real-world consequences.
           | 
           | As far as mechanism of action, T. gondii infects both neurons
           | in the brain and glial cells.
        
       | WarOnPrivacy wrote:
       | You mean if I was TOXO free, I could be an even MORE aggressive
       | driver? Totally going to mainline some Ivermectin.
        
       | prvc wrote:
       | The case for devoting resources towards developing an efficient
       | cure is becoming clear.
        
       | splittingTimes wrote:
       | Stanford neuroendocrinology researcher Robert Sapolsky Explains
       | Toxoplasmosis on the Joe Rogan podcast. Utterly fascinating.
       | 
       | https://m.youtube.com/watch?v=NroiGfNohPo
        
       | bmeski wrote:
       | So cat people can't drive well? We've always known this.
        
         | whateveracct wrote:
         | what exactly constitutes a "cat person" exactly?
         | 
         | the dichotomy between "dog people" and "cat people" had always
         | been interesting and telling to me.
         | 
         | dog people will go as far as blame you for their "reactive" dog
         | who can "tell when your nervous around him."
         | 
         | not-cat people mostly don't like cats because..the cats are
         | "rude" to them?
         | 
         | In a way, these are similar experiences. You are behaving in a
         | way the animal doesn't like, and the animal is reacting
         | negatively.
         | 
         | With the dog, there isn't much you can easily do about a dog
         | who doesn't know you and feels threatened when you stand up.
         | You're dealing with a few steps removed from a beast in that
         | situation.
         | 
         | But for cats, you can probably just be more cat-polite if you
         | actually want the cat to be nice to you. Same goes for people
         | haha
        
           | bmeski wrote:
           | I don't even know haha. All the cat people in my life are
           | vastly different drivers. The joke appeared instantly and I
           | had to pull the trigger.
        
           | gruez wrote:
           | >what exactly constitutes a "cat person" exactly?
           | 
           | >the dichotomy between "dog people" and "cat people" had
           | always been interesting and telling to me.
           | 
           | I think by "cat person" he meant less "I like cats", and more
           | "cat lady"
           | 
           | https://en.wikipedia.org/wiki/Toxoplasmosis#Society_and_cult.
           | ..
        
           | eurasiantiger wrote:
           | > the dichotomy between "dog people" and "cat people"
           | 
           | In my experience, there are many kinds of both.
           | 
           | - cat/dog people who are primarily just animal lovers and
           | take in rescue cats/dogs
           | 
           | - cat/dog people who primarily want to have a non-human
           | companion in their daily life
           | 
           | - dog people who primarily want to use a dog to aid them in
           | some activity, e.g. hunting
           | 
           | - cat/dog people who primarily want to show off their dog
           | with pride
           | 
           | - cat/dog people who primarily want to breed cats/dogs for
           | sale to other enthusiasts
           | 
           | - dog people who primarily enjoy dominating another species
           | and having them at their mercy
           | 
           | - cat/dog people who are running a kitten/puppy mill for
           | profit
           | 
           | - cat people who are themselves independent and value that
           | quality in cats
        
           | kodah wrote:
           | The joke to me seemed to be poking fun at correlation and
           | causation.
           | 
           | In a literal sense, people get pets for different reasons. A
           | lot of people get cats because they're more independent where
           | dog owners cite "having a companion" because dogs have a
           | closer relationship to humans through domestication.
           | 
           | Animals are still animals, domesticated or not. They'll get
           | fearful or angry based on correlation of past experience just
           | like you and I will. The only difference is that they can't
           | explain themselves like you and I can. Anecdotally, I know my
           | dog is terrified of fireworks, but I also know she's not gun-
           | shy. I also know she doesn't like full face masks (like
           | motorcycle helmets), and that she's ready to defend the house
           | if there's a knock at the door. All of which sound relatively
           | terrifying to the average person when she reacts to them,
           | however, when she is actually confronted with the person on
           | the other side of the door, the person behind the mask, or
           | seeing the fireworks that go "bang" she'll flop on her back
           | and ask for belly rubs.
        
             | petre wrote:
             | People who want an independent dog should get a Husky or a
             | Fox Terrier.
        
               | 11235813213455 wrote:
               | and people living in apartments could consider plants as
               | pets
        
         | kennywinker wrote:
         | I think you're going for a glib lil' fun quip, but that really
         | just sounds like sexism one-step-removed to me. The stereotype
         | of the cat lady, mixed in with the stereotype of women being
         | bad drivers. Unless there's some stereotype about men who like
         | cats I'm not aware of?
        
           | atatatat wrote:
           | Who was stereotyping?
        
           | jpxw wrote:
           | Thank god the joke police have arrived to ensure that nobody
           | is entertained inappropriately. Phew, that was a close one.
        
             | kennywinker wrote:
             | Serious question: if my reply hadn't been there when you
             | arrived would you have been entertained? If so - what was
             | entertaining about the comment
        
               | black_niggers wrote:
               | kill urself f@ggot
        
               | jpxw wrote:
               | It was a glib little quip, as you mentioned. That was the
               | entertaining part.
               | 
               | Edit: I've just noticed a particularly vile and
               | undeserved comment in reply to you, and to some extent
               | feel responsibility, as it's part of a comment chain I
               | created. I hope the mods will take action and ban whoever
               | made this comment, although by the looks it's a burner
               | account. It's quite jarring to see something like that on
               | HN.
        
               | kodah wrote:
               | Use the flag feature. If enough people flag it the
               | comment disappears. That's what I did, downvote and flag
               | all comments that don't meet the guidelines for
               | participating in HN.
        
               | kennywinker wrote:
               | All good. It seems to be gone now, since I can't see it.
        
               | black_niggers wrote:
               | kill urself f@ggot
        
           | rkk3 wrote:
           | World class mental gymnastics to insert gender identity
           | politics into a conservation about pet ownership.
           | 
           | > Unless there's some stereotype about men who like cats I'm
           | not aware of?
           | 
           | Yes, there are plenty of stereotypes about "People who like
           | cats".
        
           | dgfitz wrote:
           | Sincerely, do you get tired of this train of thought? It's
           | exhausting for me to attempt to constantly think in this
           | paradigm.
        
             | SV_BubbleTime wrote:
             | It's common now for people actively seeking any opportunity
             | to be offended on behalf of someone else.
             | 
             | There must be some odd entertainment factor to it that you
             | and I don't understand.
             | 
             | I don't know what it's like to be so self-certain and
             | absolute that I would take on responsibility of social
             | internet police.
        
               | kennywinker wrote:
               | Not really "offended". I was actually more hoping I could
               | make the original author notice some internalized
               | misogyny. I appreciate when people point out when my
               | thinking is based in bad stereotypes and assumptions. I
               | was going for more of a bros-helping-bros kinda thing.
        
               | [deleted]
        
               | Freestyler_3 wrote:
               | Kind of stereotyping/assumptious to think that because
               | someone posts something about cat people that the person
               | is a man who actually means to say women cant drive.
        
               | [deleted]
        
               | SavantIdiot wrote:
               | > It's common now for people actively seeking any
               | opportunity to be offended on behalf of someone else.
               | 
               | I never understood why people get so angry at other
               | people for showing solidarity, even if they aren't part
               | of the oppressed group.
               | 
               | Why does it make you so mad? Seriously, I don't get it.
               | 
               | Is it because no one stands up for you?
               | 
               | Standing up for a minority group that you are not part of
               | is called being part of a community, it is literally what
               | solidarity is all about. I know that is hard for a lot of
               | people on HN to understand, this place is rife with
               | mythology of bootstraps & rugged individualism.
               | 
               | By your insane logic, the only person who can stand up
               | for someone is that one person. Maybe that is what you
               | want?
               | 
               | I'm just baffled by the anger.
        
             | kennywinker wrote:
             | Yes it's exhausting. Once you see the atmospheric misogyny
             | we're all soaking in, it's very hard to ignore tho.
             | 
             | See also: https://www.theonion.com/woman-takes-short-half-
             | hour-break-f...
        
               | SV_BubbleTime wrote:
               | Thanks for following up with that. I think linking an
               | onion article from seven years go definitely adds context
               | to your point of view.
        
               | kennywinker wrote:
               | Oh, sorry is the joke not funny because it's 7 years old?
               | Because I noticed that "women are bad drivers" jokes have
               | been around since the 1920s...
        
               | [deleted]
        
               | koheripbal wrote:
               | Im not sure this is the right website for you.
        
       | JohnJamesRambo wrote:
       | Now I need Progressive to pay for a round of pyrimethamine and
       | sulfadiazine for me.
        
         | rini17 wrote:
         | Latent toxoplasmosis is literally insidious, hidden inside body
         | fat cells where antibiotics won't reach and only occasionally
         | it gets out to infect more cells. So one round is not enough,
         | you have to take antibiotics for years until all the infected
         | cells die.
        
           | eurasiantiger wrote:
           | Hmm. I wonder if there is an antibiotic prodrug that would
           | mimic glucose enough for it to be recognised by beta cells,
           | get metabolised and release the antibiotic payload inside a
           | fat cell.
        
           | nerdponx wrote:
           | Is this accepted convention?
           | 
           | It sounds a lot like the explanation for chronic Lyme disease
           | (except with nerve tissue and not fat cells), which is
           | apparently still quite controversial despite having lots of
           | anecdotal evidence to support it.
           | 
           | Also if the parasite is hiding in your fat cells, does that
           | also mean that you can't detect it in a blood test?
        
             | rini17 wrote:
             | Hmm it is possible I confused it with chlamydia. In any
             | case, if it affects behavior, there should be some chemical
             | markers too.
        
       | mortenlarsen wrote:
       | I wonder what BAC would generate the same effect.
        
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       (page generated 2021-09-05 23:01 UTC)