[HN Gopher] A soft, wearable brain-machine interface
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       A soft, wearable brain-machine interface
        
       Author : sizzle
       Score  : 87 points
       Date   : 2021-09-07 17:59 UTC (5 hours ago)
        
 (HTM) web link (spectrum.ieee.org)
 (TXT) w3m dump (spectrum.ieee.org)
        
       | 0xFACEFEED wrote:
       | Could someone explain to a dummy like me: what are the actual
       | technological bottlenecks for brain-machine interfaces?
       | 
       | Like... setting aside all the things that, given enough
       | time/effort, we'll reach some useful maximum. I'm told that with
       | ML (eg: image classification) we'll eventually train the systems
       | enough that they'll do a pretty amazing job.
       | 
       | So is it converting analog brain signals to digital? Is the rate
       | of data transmission even relevant here? What would happen if we
       | had enough "brain data" from a single person to saturate a 10
       | gigabit network? Do we have the software to do anything
       | meaningful with that?
        
         | uuidgen wrote:
         | The brain is more like a CPU implemented in FPGA than a CPU
         | synthesised into silicon.
         | 
         | Signals are only somewhat local - you get increased activity in
         | this or that region and can correlate it with what happens in
         | the brain - like power analysis attacks on crypto chips - the
         | algorithm has to recover the data from the limited, noisy
         | signal we are able to pickup.
         | 
         | You can't just put electrode in every single neuron to read its
         | state like you can't put an electrode into every single piece
         | of conductive metal on a chip - it would be to tight to fit and
         | everything would stop working.
        
         | dr_dshiv wrote:
         | So many challenges. One is that we can only receive information
         | from certain parts of the brain--those where the neurons are
         | perpendicular to the scalp. As you know, the brain is really
         | convoluted, so this makes for a very messy signal. Another
         | issue is that the raw noise makes it extremely difficult to
         | detect faint signals.
         | 
         | An approach for this is training models that have expectations
         | based on the stimuli themselves; e.g., to find neural resonance
         | with different frequencies in the stimulus.
        
         | didntknowya wrote:
         | the main problem is not software, AI, etc. It's that we can't
         | get the data reliably- i.e. current sensors are not sensitive
         | enough to pick up brainwaves/activity (esp with interference
         | from muscle etc). The gold standard is electrodes implanted in
         | a brain but is a bit invasive as an interface.
        
         | devindotcom wrote:
         | Right now the state of the art options are either surgically
         | implanted electrode arrays (invasive and very limited in what
         | they can detect), electroencephalogram type helmets (non-
         | invasive but only get very vague signals), or fMRI type imaging
         | (more precise but still only gross detail, and requires an
         | enormous complex machine).
         | 
         | There's no obvious way forward with any of these that produces
         | what you or I might consider a true brain machine interface. We
         | don't have the tech AND we don't understand the brain enough.
         | 
         | Fortunately you don't need a brain-reading device to produce
         | something useful, just like you don't need a teraflop computer
         | to go to the moon. I've written recently about an EEG helmet
         | that can be used by profoundly disabled folks to navigate a UI,
         | type, and so on, and that doesn't require a precise signal at
         | all. So I think what you'll find is while the Musks of the
         | world are chasing a sci-fi dream of what they think the
         | technology ought to be, most of the utility will come out of
         | using what it's actually capable of in a smart and
         | compassionate way.
        
         | judge2020 wrote:
         | > What would happen if we had enough "brain data" from a single
         | person to saturate a 10g network?
         | 
         | Upgrade to USB 4 :)
        
           | 0xFACEFEED wrote:
           | Derp. Corrected to 10 gigabit.
        
         | pama wrote:
         | Our brain was not built to directly transmit signals nor to
         | accept input wires to read / write signals. I am sure one or
         | the other can eventually be overcome safely. But we are not
         | there yet.
        
         | ebb_earl_co wrote:
         | Like all of WaitButWhy's articles, I think this one [0] helps a
         | person understand from the fundamentals. I linked to part 3
         | which is the section for Brain-Machine Interfaces in
         | particular, but it behooves you to read from the beginning
         | 
         | [0] https://waitbutwhy.com/2017/04/neuralink.html#part3
        
         | tbenst wrote:
         | The big challenge for non-invasive BCI is that most interesting
         | information content in the brain (e.g. speech) is encoded in
         | high frequency firing activity, and the skull acts as a low-
         | pass filter.
        
       | seph-reed wrote:
       | Do you ever feel the impulse to "ctrl-f" when you're at the
       | grocery store?
       | 
       | Imagine the feeling of going to reach for something, and
       | accidentally just envisioning moving your arm. Might be like
       | "stepping into air" when you're almost asleep.
        
         | [deleted]
        
         | 58x14 wrote:
         | When I used to regularly play a particular lane-based MOBA, any
         | time I'd need to react quickly while driving, I'd instinctively
         | feel the need to burst some variation of QWE depending on which
         | character I'd recently been playing.
         | 
         | Sometimes if I practice difficult scales (those with novel
         | movements for weak fingers e.g. left pinky and ring) on the
         | piano before typing on a keyboard, I'll mistype more
         | frequently.
         | 
         | I wonder if this type and similar phenomena is also related:
         | https://en.wikipedia.org/wiki/Phantom_vibration_syndrome
        
         | hemloc_io wrote:
         | I've had this happen when opening a cookbook. Spooky for sure.
         | 
         | Time to go outside for a bit.
        
           | [deleted]
        
       | yhvh wrote:
       | https://www.cumulusneuro.com/
        
         | fouc wrote:
         | It's striking the site is focusing on the use of it in clinical
         | trials only, and not for general purpose use yet unfortunately.
        
           | judge2020 wrote:
           | Probably requires:
           | 
           | - proven usefulness for general computer tasks
           | 
           | - must be relatively easy and quick to set up
           | 
           | - cost must be reasonable, if expensive - anything over
           | something like $2,000 is going to severely limit your
           | customer pool. A semi-automated manufacturing line will help
           | with this
           | 
           | - for good measure, a crack marketing team
           | 
           | Another consideration is that the BCI industry is moving
           | insanely fast. By the time you set up a production line and
           | start mass-producing, there might be news about a novel much-
           | better process that overshadows your product and destroys
           | sales. This is effectively what happened with VR in 2012-2018
           | when everything was super expensive; only as of recent can
           | you recommend an Index or Quest 2 to people without fearing a
           | huge leap in VR quality to be coming in the near future.
        
       | anfractuosity wrote:
       | It looks like they're using one 10x10 array of electrodes?
       | 
       | With say the traditional EEG electrodes, they seem to cover all
       | over the head (some with say around 128 electrodes).
       | 
       | I understand that they'd get a higher quality signal, but is the
       | fact they're only using electrodes over one area of the scalp a
       | disadvantage?
        
       | 58x14 wrote:
       | I have a Muse 2 [1] and a Flowtime [2]; both are consumer-
       | oriented portable EEGs using Bluetooth to transmit data displayed
       | on their respective mobile apps.
       | 
       | The Muse hardware is seriously inhibited by the same user-
       | exploitative trends we see everywhere, accompanied by meaningless
       | promises. Many researchers used the Muse SDK and API until they
       | discontinued it in 2019 [3] in favor of Muse Direct - another way
       | to force users to feed Muse their data and lock them into a
       | subscription.
       | 
       | Unsurprisingly, this was also abandoned [4] and they claim "We're
       | working on a solution that allows you to collect raw EEG data
       | using the free to download" app, which would still allow Muse
       | complete control over your authentication, use and data. Ugh.
       | 
       | At least the community has reverse-engineered the LSL protocol
       | and built a Python package [5].
       | 
       | Flowtime claimed that it offers a closed API, as they don't have
       | the resources to maintain an open API [6]. I remember somewhere
       | they claimed it was on their roadmap, but I searched again today
       | and couldn't find any support of their claim.
       | 
       | BrainBit [7] and NextMind [8] seem to provide more robust
       | developer tools, although I have no experience. Naturally, each
       | of these runs more than double the ~$200 cost of the Muse and
       | Flowtime devices.
       | 
       | I have no formal neurological education but I strongly believe
       | non-invasive EEGs, combined with novel, gamified training
       | techniques coupled with machine learning will usher in a new era
       | of digital interactions. Like the transition from tactile
       | smartphone keypads to the eventually-ubiquitous full touchscreen,
       | I expect many design iterations in both hardware and software
       | will produce utterly fascinating products.
       | 
       | I can't wait to get excited again for a product launch.
       | 
       | [1] https://choosemuse.com/muse-2/ [2]
       | https://www.indiegogo.com/projects/flowtime-biosensing-medit...
       | [3] https://github.com/sccn/labstreaminglayer/issues/30 [4]
       | https://choosemuse.force.com/s/article/Muse-Direct-Subscript...
       | [5] https://github.com/alexandrebarachant/muse-lsl [6]
       | https://www.kickstarter.com/projects/987756376/flowtime-bios...
       | [7] https://sdk.brainbit.com/ [8] https://www.next-
       | mind.com/developer/
        
         | refulgentis wrote:
         | I've been kicking around getting one of these for years, the
         | deciding factor for me is essentially "what kind of demos can
         | you pull off with these?"
         | 
         | ex. a simple "yes / no" detector would be meh, pointer control
         | would be amazing, some sort of mood detector/brain trainer type
         | apps would be _awesome_ since it'd be producing value for me
        
       | Mizza wrote:
       | Curious about these "micro-needle electrodes". If I try on my
       | buddy's helmet, is there a chance I'm going to catch hepatitis?
        
         | kortex wrote:
         | I would guess they are meant as consumables. The needles are
         | 0.8 mm long and 0.35 mm wide, pyrimidal spikes. Definitely too
         | shallow to cause bleeding but that's still quite intimate
         | contact.
        
         | stcredzero wrote:
         | I'm also concerned about how such devices will affect and be
         | affected by cavitation. Cavitation inside the skull has been
         | found to happen in concussion injuries in explosions. It's also
         | thought that it can happen with the smaller impulses coming
         | from punches and everyday impacts. Are the devices subject to
         | cavitation, particularly the long, thin parts, and what happens
         | to those long thin parts inside the brain when they are
         | subjected to cavitation?
         | 
         | EDIT: This device is only penetrating the scalp, but other
         | devices like Neuralink penetrate into the brain.
        
           | kortex wrote:
           | It's barely even penetrating the scalp. The needles (really
           | better described as spikes, they have a fair amount of draft,
           | about 20deg) only puncture the strateum corneum - outer layer
           | of dead skin cells and lipids.
        
           | mattkrause wrote:
           | This particular device doesn't even penetrate al the way
           | through the scalp, so the skull would likely obliterate these
           | long before they reach the brain.
           | 
           | Motion is a problem for things that are inserted into the
           | brain, but people have been getting DBS and sEEG implants for
           | 30 years, and it's manageable, though not totally solved.
        
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       (page generated 2021-09-07 23:00 UTC)