[HN Gopher] Vitamin D and Depression (2020) ___________________________________________________________________ Vitamin D and Depression (2020) Author : pmoriarty Score : 147 points Date : 2022-05-08 17:34 UTC (5 hours ago) (HTM) web link (www.ncbi.nlm.nih.gov) (TXT) w3m dump (www.ncbi.nlm.nih.gov) | [deleted] | jokoon wrote: | I recently wondered if bad dental hygiene can increase or cause | more depression. | | Since oral hygiene can cause bad stuff in the stomach, maybe it | can also lead to bad stuff in the digestive system... | jghefner wrote: | Vitamin D supplementation didn't affect my depression. Going for | walks to get more sunlight made it worse. | | I understand that not everything works for everyone and I wish | those around me, including my doctor, did as well so they'd stop | blaming me when their "cure" doesn't work on me. | pcurve wrote: | Would you mind sharing in what ways going for walks made it | worse for you? | jamal-kumar wrote: | If going out and walking in the sun made it worse I can only | imagine where you live must be pretty depressing. | | Portland? | jghefner wrote: | This is what I'm talking about. The idea that "going for a | walk and getting sunlight is good for depression" is so | universally unchallengable that I must live somewhere | terrible if it doesn't work for me. | chasebank wrote: | Book a two week long float down the middle fork of the | Salmon river and let me know how you feel after. | jamal-kumar wrote: | Yeah, I don't know anyone happy there. | | In before excuses - Leave | resfirestar wrote: | There can be underlying anxiety issues that make going out | like that quite a stressful event, especially at first, and | even traumatic if something bad does end up happening. Or | sensory processing issues associated with autism spectrum | disorders that make bright sunlight feel unpleasant. Not to | downplay the general idea: certainly for most people who feel | a little blue, or even crappy enough for long enough to | qualify for a diagnosis of major depression, getting out more | is likely to be helpful on its own (and that's why therapists | generally recommend it). But to the GP's point, the lack of | distinction between people with a more ordinary (but quite | painful!) set of problems and people with a bunch of | comorbidities that they're likely not aware of is really | frustrating, especially if they're using the internet to look | for ideas and find a bunch of people generalizing the easy | fix that cured their depression to the entire population. | docmechanic wrote: | Off topic, but perhaps of interest to anyone dealing with | depression. Twenty five years or so ago, someone recommended that | I try St. John's Wort. I had a negative reaction - bad skin rash | - but the Mayo Clinic mentions that some studies show it "can be | effective for treating mild to moderate depression." | | https://www.mayoclinic.org/drugs-supplements-st-johns-wort/a... | lordentropy wrote: | Daily morning and afternoon exposure to bright light might | actually be more important to reducing depression than direct | vitamin D supplementation. Low vitamin D might just be an | indicator that you are not getting enough sunlight. Sunlight also | affects melatonin and serotonin levels, and synchronizes your | Circadian rhythm. Not sure why that article doesn't talk about | Seasonal affective disorder (SAD), and how bright light therapy | is considered an effective treatment for it. | kingcharles wrote: | I just went over 8 years without seeing the sun (jail). I | wonder what the long term effects are? | adfjalkfja wrote: | Had a consult with a sleep doctor, he stressed the importance | of getting out for morning light for at least 30 minutes with | no sunglasses. | juve1996 wrote: | Anecdotally agree with this. I have vitamin D deficiency, was | given 50,000 IU a week vitamin D to get it up. Never worked. | | Went to the beach one week and got blood tested again and my | vitamin D levels climbed significantly. Now I make it a point | to get outside and sunlight | treeman79 wrote: | Had super low Vit D. Was stuck in bed for a year. A few | months of Vit D and a few other diet and supplements changes | and I was out kayaking every weekend. | | My experience anyway | donthellbanme wrote: | The heaviest man in Mexico was bedridden for years. He was | depressed, but besides being humongous, and trapped in a | bed; one of his biggest complains was muscle aches. | | A doctor gave him vitamin D supplements and he said the | pain went away. | | It made a bit of sence to me, but the amount of food this | guy consumed daily was staggering. I just wouldn't think a | person would be deficient in D with the amount of animal | products this man consumed. I just assumed even though he | never saw the light of day for 15 years. | | My point is it just suprised me. | | Antidotially, I have been depressed (dysthymia--low level) | for a good 30 years, and found sunlight didn't help me. I | don't eat a lot, but i'm not a vegetarian either. | | I actually feel better during the winter. I do have | allergies though. | | According to my doctor, all he ever said about depression | is "All my patients are different. Oh, my fee will be | $----. Your depression is situational.". I know he is | partially right. (He doesn't overcharge me compared to the | horror stories I have heard here. I just believe most | psychotropic drugs should not require more one office | visit, especially if you are on a low dose, and not abusing | them.) | interactivecode wrote: | What dose and diet changes did you do? | treeman79 wrote: | 3,000u daily. Switched to AIP diet. | | Six months earlier had started. Started magnesium, b12, | fish oil, Vit E. | | Now I take a 5000u/k2 combo. | | Now on LDN in addition That seems to be the final major | piece to fully normal life. | csdreamer7 wrote: | > was given 50,000 IU a week vitamin D to get it up. | | It should have gone up significantly. I wonder if your body | has a problem with Vit D absorption. I was put on the same | dose of vit d for a treatment and I felt it within 20 | minutes. | chrisco255 wrote: | Is vitamin D fat soluble? If so, pretty sure it needs to be | consumed with fat. That's partly why it's common in milk. | Jtsummers wrote: | It is fat soluble, but it doesn't _need_ to be consumed | with fat. It 's believed that that will help improve | uptake, though. (I don't, I take it in the mornings long | before my first meal and that seems to be effective for | me based on my test results.) | chrisco255 wrote: | https://www.jandonline.org/article/S2212-2672%2814%290146 | 8-3... | | "The mean peak (12-hour) plasma vitamin D-3 level after | the dose was 32% (95% CI 11% to 52%) greater in subjects | consuming fat-containing compared with fat-free meals | (P=0.003)." | nanidin wrote: | It's common in milk because it helps with calcium | absorption. | trompetenaccoun wrote: | A lot of modern "problems" can be solved this way. The term | _koyaanisqatsi_ comes to mind, life out of balance. | geoduck14 wrote: | >Went to the beach one week and got blood tested again and my | vitamin D levels climbed significantly. | | Well, I think I just justified my beach vacation. Thanks! | hammock wrote: | The point was that sunlight does more than raise vitamin D, | not that it's better than supplementation at raising vitamin | D. | annamargot wrote: | Latitude matters though. The farther north you are the more | time in the sun you'd need. In some far north places, the sun | you do get is not strong enough to get any Vit D. | | http://web.archive.org/web/20210302053343/https://jaoa.org/a... | | https://www.grassrootshealth.net/document/sunshine-calendar/ | thinkingemote wrote: | Indeed, the UK which is further north than the majority of | Canada's population has effective vitamin D from the Sun only | from March to September. Spring Equinox to autumn equinox | basically. The sun is too low even though it might be much | warmer than lower latitudes! | noneeeed wrote: | Yurp. I live in the south of England and even here I take | vit D for pretty much that time period or I end up with | little to no energy. I always make sure to go outside as | much as I can, but when the sun is coming up at 8am and has | gone down by 6pm it's pretty hard to get enough daylight | and also work. | AnthonBerg wrote: | Sunlight's effects on body chemistry also have a damping effect | on inflammation. It's a funny thing. | | Sunlight has an impact on many chemical processes in and on the | body. One example: Our skin is coated with a bunch of | chemicals. There's a number of different acidic chemicals. | These are known as the "acid mantle": | https://en.wikipedia.org/wiki/Acid_mantle | | One of these substances is _urocanic acid_. The body | manufactures it as the trans-isoform. UV light - as in sunlight | - causes it to change into _cis-_ urocanic acid. (Ultraviolet- | induced isomerization.) | | Cis-urocanic acid fits a certain serotonin receptor - type | 5-HT2A. Cis-urocanic acid is a 5-HT2A agonist. That receptor is | known to be profoundly immunomodulatory. | | It's super interesting! There are some recent papers on it like | " Cis-urocanic acid, a sunlight-induced immunosuppressive | factor, activates immune suppression via the 5-HT2A receptor" - | https://pubmed.ncbi.nlm.nih.gov/17085585/ | | "Molecular basis for cis-urocanic acid as a 5-HT2A receptor | agonist" - | https://www.sciencedirect.com/science/article/pii/S0960894X0... | | This is absolutely fascinating. I think people take me as a | crackpot when I point to these papers. These are just simple | and solid papers from molecular biology :) | honkdaddy wrote: | > That receptor is known to be profoundly immunomodulatory | | Any change for a layman's explanation on what that means? | This seems super fascinating but admittedly above my | understanding. | lisper wrote: | immunomodulatory (immuno-modulatory) = modulates (i.e. | controls) the immune system | supertofu wrote: | Anecdata: I grew up in LA. I was always relatively healthy. | Moved to NYC. Developed autoimmune disease by my 6th year in | NYC. | | I often wonder if I would have developed the disease if I had | stayed in LA. | pram wrote: | I think changing location does have a huge effect. | Personally when I go to LA or SF (from Texas) I get sick | 100% of the time, without fail. | Tijdreiziger wrote: | For some reason I was often sick when I lived in | Stockholm (Sweden). A friend there mentioned having the | same problem. | nradov wrote: | Sunlight exposure also stimulates nitric oxide production, | which is important for circulatory system health. | desro wrote: | Thank you for this fascinating comment! I can't wait to read | through all of your links. | gabereiser wrote: | You, sir, just blew my mind. I have some reading material to | go through. This is fascinating indeed!! | BiteCode_dev wrote: | And yet lots of dermatologists will tell you to avoid | sunlight. | | The medical community is full of contradictions. | 2muchcoffeeman wrote: | Until recently not going out much wasn't a big factor. | | I've been feeling sicker than usual lately. Stupid amount | of rain in NSW. Went out yesterday morning on a bright | sunny day and suddenly I felt much better. | herodoturtle wrote: | Everything in moderation. | | EDIT: Except lava. | BiteCode_dev wrote: | At first I read "except Java" | blep_ wrote: | Lowercase L looks like capital i in some fonts. | | Clearly it's Iava, the Latin word for Java. Quidquid Iava | quondam scribum, omni currum, sed delenda est. | _Algernon_ wrote: | Still true | SnowHill9902 wrote: | It's actually quite reasonable and intuitive that an integral | part of our environment i.e. the sun is beneficial or at | least has modulatory effects on ourselves. It's too much a | reductionist approach to think sunlight -> bad because of | it's immediate associations with some types of skin cancers. | anoplus wrote: | I am thinking the same, and in a midst of self experiment where | I ensure I get a decent dose of just seeing the world in bright | daylight. Week into it and my sleep feels pretty solid. Easy to | avoid daylight when working indoors all day. | jollybean wrote: | Came here to say this: | | VD may be it, or even indirectly a measure of 'not getting | outside' enough. | | Even the sunlight may not be it, literally a walk in the woods | might be providing the effect. | | Or rather 'spending too much time in our own minds' etc.. | digisign wrote: | Bright, direct light seems to be a major component, which is | not what most people think of being in the "woods." See: | | https://news.ycombinator.com/item?id=31306477 | ahmedfromtunis wrote: | Maybe the relation is not as direct as we might think at first. | | Maybe the vitamin D deficiency is keeping people from going out | more, which makes them feel isolated, not engaged fully with | their friends and family which, in turn, pushes them to | depression if they're prone to it. | | And that may explain why it seems that, as the writers of this | paper mentioned, when some of the subjects get vitamin D the | depression goes away. This can be caused by the effect of the | intake on their ability to gain their more active way of life. | jimhefferon wrote: | I live pretty far north. For months at a time here there is | basically no sunlight. Sometimes people try to sell you | artificial light of one kind or another. Do they work? | SapporoChris wrote: | Some UV lamps have been shown to help the body make Vitamin D. | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846322/ | | I would recommend checking to see if you're actually getting | low Vitamin D level during the winter and talk to a doctor to | get their opinion on best treatment. | drited wrote: | My understanding is that 10000 lux bulbs are accepted treatment | for SAD. I live in a dull country and bought one despite not | suffering from SAD. Anecdotally I find it great to help wake up | in the dark winter mornings. | tkiolp4 wrote: | I'm from Portugal. I've been living in Germany for 3 years. Last | winter I was feeling very tired when walking, even dizzy. Doctor | said I got very low levels of vitamin D. I never felt depressed, | though. | [deleted] | SirensOfTitan wrote: | Interestingly the fix to my seasonal affective disorder was a | move a couple years ago into an apartment with no blinds and tons | of sun in the morning (our previous place had black out blinds). | We never got to adding blinds, and we have no intention to at | this point--I wake up with sunrise naturally nowadays around 6am | and haven't had SAD since. | | I'm of the impression that black out blinds are generally poor | for sleep hygiene (unless you're in a really bright place and | they're a necessity), as they disrupt some of the most natural | and most potent zeitgebers available. That isn't to say that a | knowledgeable and enterprising person couldn't employ black out | blinds when crafting their sleep environment, but most people | won't balance the different influencing factors thoughtfully. | ta988 wrote: | Depends, they can hide streetlight too which can be disturbing | sleep pretty intensely... | hirundo wrote: | I'm a remote worker. After an early morning standup I go outside | and do yardwork in a big yard for a half hour to an hour, | whenever I can. This is a pleasure that I've come to defend | fiercely. When I sit back down at the keyboard my improved | attitude and energy are such that I believe I make up that time | in productivity before lunch. Don't know how much of that benefit | is from increased vitamin D, from the forest bath, or from the | exercise oxygenating my neurons. I doubt I could replace it with | a pill. | ralusek wrote: | Sunlight and gardening have had such a dramatic impact on the way | that I feel, it's unbelievable. | alleskleber wrote: | For me sunlight and some light exercise everyday were a game | changer. I had tried Vitamin D supplements (1000 IU daily) | before but there was barely any noticable effect. | floppydiskette wrote: | I don't think that's enough, I needed 5k daily before it | started working. My blood tests all come back in the correct | range now. | k__ wrote: | Good to know. | | I was diagnosed with low VitD and they said I should take | like 1k-2k, but I didn't feel much. | stjohnswarts wrote: | 1000 is actually way below what you need probably, my doc put | me on 2500 a day and it wasn't enough, I've moved to 5000 and | been "normal" level ever since for several years for my | annual checkout/blood/urine tests. If you have brown/black | skin it can be even more, but better to start low and figure | out what is enough under observation of a doctor. | throckmortra wrote: | My first winter in NYC was very rough and I didn't understand why | at first. I got a blood test at the doc and he said my vitamin D | was very low. I committed to walking in the sun at least a half | hour a day, weather permitting, and I never really had issues | again. Part of the issue was I was spending a lot of time walking | outside but not in sunlight due to the tall buildings. Just my | anecdotal 2c | tayo42 wrote: | I finally got a chance to move south and this was the first | winter I didn't spend being weird and existential about | everything. Just kind of enjoyed life. | carabiner wrote: | I live in Seattle and have been depressed for a while. I had my | Vitamin D3 levels checked via blood test, and they were really | low. Started taking 5,000 IU per day, and I feel exactly the | same as before. | numinoid wrote: | Anecdotally, I had to bump up to 10,000 IU to see a | difference. | olah_1 wrote: | I have never felt an affect from oral vitamins in _any_ | situation. | | Sitting in the sun however seems to do more than just | "increase vitamin d levels". The sensation is just | overwhelmingly lovely. It seems to reduce cortisol, makes you | feel tired in a euphoric way. Animals love to warm their fur | in shafts of sunlight too. | | Perhaps we should be thinking more in terms of joyful | activities in general and less trying to biohack. | AlbertCory wrote: | > Animals love to warm their fur in shafts of sunlight too. | | Indeed. My dog _always_ lies in the sun for a while when he | goes outside. Once he 's warm enough, he moves to the | shade. Animals know. | supertofu wrote: | My blind cat always seeks sun spots as well! | __ryan__ wrote: | That narrative might work for you, but the bio-hack | narrative might work for others. | | Maybe the takeaway is to go into things with a positive | attitude but also take a personal inventory and adapt if | something that is _supposed_ to work doesn't work for you. | DoreenMichele wrote: | Seattle is extremely damp and temperate, so you see a lot of | mold and allergens there year round. | | If redressing your vitamin D levels doesn't fix it, look for | hidden mold and/or allergies. | TameAntelope wrote: | 5k IUs is well beyond anything your body has a use for, and | in fact is above what your body can tolerate! [0] | | > RDA: The Recommended Dietary Allowance for adults 19 years | and older is 600 IU daily for men and women, and for adults | >70 years it is 800 IU daily. | | > UL: The Tolerable Upper Intake Level is the maximum daily | intake unlikely to cause harmful effects on health. The UL | for vitamin D for adults and children ages 9+ is 4,000 IU. | | So it's possible your 5k IUs were causing you more harm than | good. | | [0] https://www.hsph.harvard.edu/nutritionsource/vitamin-d/ | mikenew wrote: | Those numbers are wrong by an order of magnitude, because | the original estimation was based on faulty math. The | actual dose needed to bring serum levels up for most people | would be far higher. | | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210929/ | TameAntelope wrote: | I'm going to go ahead and trust Harvard Medicine over a | single study that has since gone largely uncited, and was | published in "Nutrients" which carries an h-index of 115 | (Nature, for example, carries an h-index of 1226) [0][1]. | | [0] https://www.scimagojr.com/journalsearch.php?q=1970018 | 8323&ti... | | [1] https://www.scimagojr.com/journalsearch.php?q=21206&t | ip=sid&... | wholien wrote: | Highly doubt 5k IUs is the issue. Some select quotes from | "Vitamin D Is Not as Toxic as Was Once Thought: A | Historical and an Up-to-Date Perspective" by Michael Holick | in Mayo Clinic Proceedings [0]: | | > Ekwaru et al recently reported on more than 17,000 | healthy adult volunteers participating in a preventative | health program and taking varying doses of vitamin D up to | 20,000 IU/d. These patients did not demonstrate any | toxicity, and the blood level of 25(OH)D in those taking | even 20,000 IU/d was less than 100 ng/mL. | | > The evidence is clear that vitamin D toxicity is one of | the rarest medical conditions and is typically due to | intentional or inadvertent intake of extremely high doses | of vitamin D (usually in the range of >50,000-100,000 IU/d | for months to years). | | [0]: Holick, https://www.mayoclinicproceedings.org/article/ | S0025-6196(15)... | | [1]: Ekwaru et al, | https://pubmed.ncbi.nlm.nih.gov/25372709/ | TameAntelope wrote: | [0] is an editorial and [1] seemingly went unpublished, | other than in PLOS One, which means it goes through a | _very_ different peer review process than most other | journals (that is, no peer review on its content, only on | its methodology). | nicoburns wrote: | That assumes your body is absorbing all of it. I suspect a | lot of people's aren't, hence the high doses. I have found | for example that 1000iu in the form of drops under the | tongue has dramatically more effect than 1000iu in the form | of a chewable tablet. | mupuff1234 wrote: | Did you do another blood test to check if the levels changed? | Trasmatta wrote: | Since you're in Seattle, check out bright light therapy as | well. | civilized wrote: | In this and the GP we have Vitamin D and depression in a | nutshell. | carabiner wrote: | To answer a bunch of questions: Yes, I had bloodwork done | later showing my D3 level in the typical range. Whether that | was due to the supplement, or diet, or lifestyle I can't say. | I take 1 pill (USP certified) on average 2-3x per week. So | not every day. | | I've got treatment resistant depression and have tried | probably everything else you're about to suggest. The only | thing that kind of helped was dihydrotestosterone, but that | is now illegal in the US. | laurentlbm wrote: | I have TRD too and tried so many things. It sucks. | trts wrote: | Also in Seattle, also recovered from treatment resistant | depression. I recommend looking into TMS. I wish I had done | it much sooner. | | Wish you luck, it's been an especially gloomy year here. | carabiner wrote: | Tried it through Neurostim in Bellevue. Didn't work. | Waiting for the Stanford SAINT protocol to be approved. | trash3 wrote: | Check your diet. Just because you take vitamin d supplements | doesn't mean it gets absorbed into your bloodstream. | xwowsersx wrote: | did you get blood work done again though after taking the 5K | IUs for a while? it's possible that the supplementation | didn't bring your Vit D levels to within range and you need | 10K IUs+. Of course, I'm not suggesting this would | necessarily help with your depression, but just pointing that | you gotta be scientific/anecdotal when it comes to | supplementation/blood panels | femiagbabiaka wrote: | 10k IU's a day is what it took me. I found that value almost | by accident, while starting to follow Stan Efferding's | Vertical Diet, which recommends that as a part of a suite of | daily vitamins (it is much better than the name belies). IMO | anyone who works a desk job should take 10k IU's daily. I | fell out of the habit during covid quarantine and my levels | (and my mood) were dangerously low when I came out on the | other side. | tomatowurst wrote: | 5000 IU is really too much. At best 2000, 2500 IU is good. | dralley wrote: | 5000 isn't too much when you're catching up from a | deficiency. | Vecr wrote: | No, 5000 IU per day is generally considered the highest non | megadose. Make sure it is good quality (D3, USP in the US), | and it should be fine. Some people say also to take K2 | (also make sure it's USP in the US), but I'm not sure the | exact supposed mechanism of protection from adverse effects | from D3. Something about preventing calcium from leaching | from the bones and accumulating in the blood, I think. | pmoriarty wrote: | _" Vitamin D controls the absorption of calcium into the | blood. Vitamin K2 controls where that calcium ends up._ | | _" Over-supplementation of vitamin D3 without ample | vitamin K2 leads to problems of excess calcium._ | | _" If calcium isn't laid into bone, it will find itself | in other tissues, like your arteries. Calcium in the | arteries is BAD. It contributes to atherosclerosis and | vessel stiffness."_ | | https://dralexrinehart.com/articles/the-vitamin-d-and- | vitami... | LinuxBender wrote: | I use 60,000 to 90,000 IU's per day and have been doing so | for years. The most I have taken in a 24 hour period is | 140,000 IU's. There is no way I could have started off at | those levels however. It would have induced major | hypercalcemia had I done that prior to mobilizing all the | stored/misplaced calcium in my gut and vasculature. I am | not suggesting anyone else do this. One must have a | specific need when doing this. | | I only mention this to say that one can go well above the | RDA/RDI that are highly contested to be far too low for | modern diets, environmental inputs and lifestyles. | TameAntelope wrote: | > Taking 60,000 international units (IU) a day of vitamin | D for several months has been shown to cause toxicity. | This level is many times higher than the U.S. Recommended | Dietary Allowance (RDA) for most adults of 600 IU of | vitamin D a day. [0] | | I think you may be poisoning yourself. | | [0] https://www.mayoclinic.org/healthy- | lifestyle/nutrition-and-h... | LinuxBender wrote: | That would certainly be true had I done that from day one | as I had mentioned. Their documentation as with most | medical documentation is based on the lowest common | denominators. They will not risk explaining why one might | do what I am doing. | TameAntelope wrote: | It seems true without qualification. | | What you're saying here has a lot in common with "woo", I | hope you realize. | LinuxBender wrote: | I suppose time will tell. I've been doing this a number | of years. I will check back in a few more years to see | how things are going. Honestly the cholecalciferol levels | are the least taboo of the biohacking I do with myself. | The more risky testing I did was to see how high I could | go on the tocotrienols, tocopherols and fibrinolytic | enzymes before I ran into bleeding. | TameAntelope wrote: | Aren't you concerned that your data is super subjective | as you're collecting it on yourself? | | It sounds like there are a _ton_ of confounding variables | possible, not to mention your own personal biases in | interpreting any potential causality. | stjohnswarts wrote: | That's a crazy amount. I had a very low blood test | started supplementing with k2/5000 vitamin d several | years ago and my blood levels have been fine ever since. | mountainriver wrote: | It really depends on the person. You just need to monitor | your blood levels | cashsterling wrote: | It can take a while for your Vit-D levels to rise, even with | supplementing 5k IU per day... I would check your levels | again. | | And, of course, Vit-D is not the only contributor to | depression so it might be good to see a GP and/or get a | general blood panel done. | KennyBlanken wrote: | In the northeast during wintertime, it's impossible to | accumulate enough vitamin D from sunlight, especially not from | such a short period of time, fully clothed. | | Even if you were not fully clothed, there's so little UV making | to you because of the sun's low angle and distance. | pigtailgirl wrote: | wildly speculating from an evolutionary perspective - it | reasons that we'd evolve such that our moods are better in | light - otherwise there would be another push to stagnate vs | become exposed to more - such that evolution can do it's thing | - evolution tends towards evolution after all - | legulere wrote: | > Overall findings were that there is a relationship between | vitamin D and depression, though the directionality of this | association remains unclear. | | Vitamin D really seems to be a good example of correlation does | not imply causation. I'm looking forward to when the Vitamin D | hype ebbs off and when we know what Vitamin D actually helps | with. | legopeice wrote: | In Norlisk, Russia, the children get doses of Ultra voilet light | to combat the lack of sunlight. | | https://allthatsinteresting.com/norilsk#8 ___________________________________________________________________ (page generated 2022-05-08 23:00 UTC)