[HN Gopher] Why thinking hard makes us feel tired
       ___________________________________________________________________
        
       Why thinking hard makes us feel tired
        
       Author : rntn
       Score  : 147 points
       Date   : 2022-08-11 19:15 UTC (3 hours ago)
        
 (HTM) web link (www.nature.com)
 (TXT) w3m dump (www.nature.com)
        
       | jyounker wrote:
       | Being poor takes a huge amount of mental effort. This would
       | explain in physiological terms why it's hard to make good
       | decisions when you're poor.
        
       | havblue wrote:
       | This has always been an embarrassing issue for me: Lose track of
       | the lecture. Try really hard to concentrate and catch up. Nod
       | off.
        
         | throwaway81523 wrote:
         | I suspect that nodding off in meetings or lectures, a lot of
         | time, is caused by too much CO2 in the air, caused by poor
         | ventilation and a room full of exhaling people.
        
       | eminence32 wrote:
       | It seems like the headline overstates the findings (as headlines
       | are wont to do), but it's interesting nonetheless
       | 
       | > participants who spent more than six hours working on a tedious
       | and mentally taxing assignment had higher levels of glutamate
       | 
       | > too much glutamate can disrupt brain function, and a rest
       | period could allow the brain to restore proper regulation of the
       | molecule
       | 
       | It sounds like the next step is for some studies on the effects
       | of glutamate
        
         | 1MachineElf wrote:
         | Glutamate can act as an excitotoxin. Excitotoxicity is believed
         | to be associated with neurodegenerative diseases.
         | 
         | https://www.frontiersin.org/articles/10.3389/fnins.2015.0046...
         | 
         | https://www.frontiersin.org/articles/10.3389/fncel.2020.0005...
         | 
         | Related- conflicting research findings and anecdotes on
         | glutamate toxicity from MSG consumption might indicate certain
         | people are more susceptible to the negative effect than others.
         | Raising this question often invites comments on: whether or not
         | cautioning against MSG is actually racist; misdirection about
         | the sodium being the prime issue with MSG; and comments from
         | those with vested interest in MSG (MSG producers, any food
         | producer with MSG, Yeast Extract, or "Natural Flavorings" in
         | their ingredients list, etc.)
        
           | bryceacc wrote:
           | from the first link:
           | 
           | >L-glu along with glutamine is the most abundant free amino
           | acid in the central nervous system
           | 
           | this would suggest that L-glu is highly regulated in the
           | body. Abundance usually means there should be storage of it
           | if level swings can bring "inbalance" to it's usage.
           | 
           | on top of that, from this study:
           | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698427/
           | 
           | >In the brain, Glu, which is locally produced completely de
           | novo from glucose, acts as a major excitatory
           | neurotransmitter, and its activity regulates synaptic
           | plasticity, learning, memory, motor activity, and neural
           | development. But dietary Glu is almost impermeable into the
           | circulating blood. Also there is the blood-brain barrier
           | against Glu in between blood and brain so as to not to
           | incorporate into it the brain.
           | 
           | if high MSG(or just G from other sources) consumption did
           | cause neurodegenerative diseases, shouldn't we see that data
           | clearly in places that consume more in culture?
        
         | [deleted]
        
       | Phileosopher wrote:
       | I've noticed this phenomenon anecdotally. It seems like my
       | impulse to NOT eat junk food goes down significantly on the days
       | I drive home after working on a hard mental problem. On easy
       | days, I'm craving celery.
        
         | skinnyarms wrote:
         | There was an old (but popular) study that showed people were
         | less likely to make healthy snack choices when they were asked
         | to memorize more digits.
         | 
         | https://www.jstor.org/stable/10.1086/209563#metadata_info_ta...
        
         | Silverback_VII wrote:
        
       | jackconsidine wrote:
       | Grandmasters apparently lose 6000 calories during classical chess
       | games [0]. That's a few marathons worth of calories.
       | 
       | [0] https://www.espn.com/espn/story/_/id/27593253/why-
       | grandmaste...
        
         | mtlmtlmtlmtl wrote:
         | 6000 calories seems absurd. But having played chess tournaments
         | I have lost a bit weight during them despite eating generous
         | amounts of bacon, eggs, hash browns etc at the hotel breakfast,
         | then more crappy fast food in the evening, with mostly sleeping
         | and relaxing in between. So I feel like there must be something
         | to it. Although 6000 kcal in one game is ridiculous, even
         | factoring in nervously pacing the playing hall when it's not my
         | move.
        
         | Tenoke wrote:
         | This myth is complete nonsense, I'm not sure how people still
         | share it. The author provides no evidence and simply made some
         | sensationalists estimates based on heart rate and blood
         | pressure during games.
        
           | goostavos wrote:
           | Hacker News always has crazy takes when it comes to anything
           | diet related. It's always strange.
           | 
           | I totally agree: it's completely preposterous that they're
           | burning 6kcal sitting still regardless of how much they're
           | thinking. People don't seem to realize how hard it is to burn
           | that many calories when _moving_. That is advanced athlete
           | levels of caloric burn. Does this caloric burn similarly
           | apply while they 're "training", or just at tournaments? Do
           | they need to put down Olympic level meals every day just to
           | sustain?
           | 
           | What about other people who's job is thinking? Are
           | mathematicians also forced to devote a significant part of
           | their day just to ensuring can chew through 6000 calories
           | worth of food? Or is there something about board movements
           | that consumes extra calories? L shape? 3 calories. Straight
           | line: one calories. If we could pin down which type of
           | thought burned 100x more calories, we'd be onto something
           | powerful here.
        
             | cecilpl2 wrote:
             | > Hacker News always has crazy takes when it comes to
             | anything diet related. It's always strange.
             | 
             | HN has crazy takes on everything not within the very narrow
             | sphere of tech expertise that is common to everyone on this
             | board.
             | 
             | You notice it for diet-related things since you are a
             | (relative) expert on that topic.
             | 
             | But it's also the case for anything economic, political,
             | scientific, or sports or hobby related, and so on.
        
             | systemvoltage wrote:
             | Actually, it is not HN, but generally nutrition is one of
             | the most bullshitted topics in the world. Everyone has
             | their perspective completely conjured up from thin air.
             | 
             | I don't trust any of these from any person:
             | Nutrition       Financial Advice       Audiophile Advice
        
           | partiallypro wrote:
           | I'm sure they are burning more calories, but I doubt it's
           | 6000.
        
             | lemonlime wrote:
             | No one who understands how much 6,000 calories is could
             | make this claim.
             | 
             | That would mean they need to eat 8,000 calories a day for a
             | normal 2000 calorie diet. That's like Michael Phelps level.
             | That's like: leave the tournament, go back to your hotel
             | and eat 7-8 medium dominos _entire_ pizzas in a sitting. I
             | hope I don 't need to explain that this is not what chess
             | masters are doing.
        
           | rossdavidh wrote:
           | The article claims that breathing rate TRIPLES during chess
           | tournaments. I don't know if that's true, but if it is, then
           | there is something pretty intense going on. If I tripled my
           | breathing rate for an extended time period I'd probably pass
           | out or something.
        
           | jackconsidine wrote:
           | After reading _Behave_ , I hold Sapolsky in high regard. Even
           | if he provides weak evidence for the claim, the grandmaster
           | in the article loses 15 pounds- or a whopping 11% of his body
           | weight- on average during a 10 day tournament which is
           | striking.
        
             | yoyohello13 wrote:
             | I think people are conflating "weight" with "fat". It's
             | very believable to me that they lost 15lbs in 10 days, some
             | fat, probably mostly water.
             | 
             | I know my weight can fluctuate as much as 10lbs in a day
             | depending on how much I've been sweating, eating, drinking,
             | exercising over the course of the day.
        
             | czx4f4bd wrote:
             | Still not burning 6000 calories.
             | 
             | > In our study, we found calorie expenditure during chess
             | competition (156.8 +- 65 kcal) and during running exercise
             | (282.9 +- 82.7 kcal) were significantly different from each
             | other, simply due to the overload effect of skeletal
             | muscles during exercise.
             | 
             | https://journals.lsu.lt/baltic-journal-of-sport-
             | health/artic...
        
             | heavyset_go wrote:
             | This can simply happen because of a change in eating and
             | drinking habits during a 10 day tournament.
        
               | ARandomerDude wrote:
               | This take seems overly skeptical to me. Regardless of
               | truth of the 6,000 calorie claim, that kind of weight
               | loss is extreme in such a short amount of time.
        
               | lemonlime wrote:
               | To the contrary, you're being underly skeptical. This is
               | a huge claim to base of a sample size of one guy at one
               | event.
               | 
               | To state the obvious that I hope doesn't need to be said
               | to this audience: a sample size of one tells us exactly
               | nothing. What's saying this one guy one time didn't have
               | a nasty stomach bug?
               | 
               | A crazy claim like this requires some kind of study not
               | just one guy's story.
        
               | dylan604 wrote:
               | Doesn't stress come into play here too?
        
               | idontpost wrote:
               | That's a 5200 calorie deficit per day.
               | 
               | So no, not really. At least not without significant
               | dehydration.
               | 
               | I'm more skeptical of the weight loss claim itself.
        
               | washbrain wrote:
               | Well, up to 8lbs could be water weight. If you have
               | excess calories, your body will retain water. If you
               | disrupt that excess you'll rapidly lose 8 to 10 lbs.
               | Weight loss often has great results in week one, then
               | levels off, so a portion of this _could_ be attributed to
               | eating less and increased stress during a tournament.
        
               | BlargMcLarg wrote:
               | 8lbs if you're already severely overweight or loaded on
               | carbs, maybe. These guys don't exactly look like they are
               | doing either of that. To put it in a different
               | perspective, that amount of weight loss beats out strict
               | waterfasting at the same weight. You can't get much more
               | strict than straight-up dehydrating (because we all know
               | dehydrating yourself prior to a mental exercise is a
               | great idea) or doing rigorous exercise outside of that.
               | 
               | And no, chess is not rigorous exercise. If it was, the
               | room would be too hot for them to wear suits and tuxedos.
               | Those burned cals have to go somewhere. For the
               | unconvinced, try jogging or lifting 2000 calories worth
               | in a suit at room temperature or slightly above without
               | taking it off.
        
               | SketchySeaBeast wrote:
               | I bet food poisoning would do it. Because, like you said,
               | they aren't burning those calories - 6,000 calories in a
               | single chess game would leave them in a giant pool of
               | sweat.
        
               | al_be_back wrote:
               | not unless there is such a change, and it has to be
               | significant to loose such weight. what does happen though
               | is an increase in mental strain as the tournament
               | progresses.
        
             | hasperdi wrote:
             | It could be attributed to stress, perspiration and change
             | in water intake behaviour. In other words water weight.
        
       | dalmo3 wrote:
       | They should study people who spend 6 hours in meetings next.
        
         | vorpalhex wrote:
         | Meetings are taxing. You're trying to ingest the presented
         | information, social cues/emotional states and often times
         | keeping an eye on slack or what have you.
        
       | sebastianconcpt wrote:
       | After some intense code challenges I did felt exhausted. I learn
       | a lot too because they were out of my comfort zone. I felt like
       | kind of needing to recover resting more the next two days.
        
       | NotTameAntelope wrote:
       | Brilliant work, and the researcher involved seems quite humble,
       | despite her impressive discovery.
       | 
       | Where in the world is Carmen Sandi's ego?
        
       | foxbee wrote:
       | I lost 2kg trying to center a div once.
       | 
       | Jokes aside. Interesting article. I think the title assumes an
       | answer but in reality the article is a gateway to further
       | studies. Worthwhile read nonetheless.
        
       | a_c wrote:
       | I don't know which is more tiresome, 3-4 hours of focused
       | programming and thinking, or 8 hours attending two children below
       | 5.
       | 
       | They are both tiring, but differently. Intensive programming is
       | like working hard at the gym. Tiring, but content. Attending
       | children is low intensity in attention, but constantly vigilant.
       | And you are expected to pay that kind of attention for another
       | maybe 4 years. Very different kind of tiring indeed, both makes
       | you unable to focus afterwards. So while thinking hard makes us
       | tired, not thinking hard can also makes us tired.
        
         | keyle wrote:
         | It's true. I have two young ones and I'm a shadow of my old
         | self when it comes to my ability to dive into deep work.
        
         | fartcannon wrote:
         | It really is the vigilance. It's hard to explain to people who
         | haven't experienced it. I certainly tried to understand my
         | colleagues who had kids, but it turns out it's quite a bit
         | harder than the hardest I imagined. Nowadays I'm a part time
         | developer, and the rest of the time, I'm the primary care for a
         | toddler.
         | 
         | Programming at work is my time off.
         | 
         | You have to be react so quickly to certain things that it keeps
         | you totally wound up. You see them pick something up off the
         | ground and wonder, 'what is that, are they going to eat it' and
         | instinctively you sprint half way across the room to grab what
         | turned out to be a cheerio from their mouth. It's almost always
         | a cheerio. But your brain won't let you rest if there's even an
         | impossibly small chance it's a battery or I dunno, glass or
         | whatever, it doesn't matter how many times you check, you can
         | always imagine something. It's exhausting.
         | 
         | I'm rambling because I'm tired. :)
        
           | kortilla wrote:
           | Protip: store your cheerios in the box they come in rather
           | than on the floor to disambiguate this scenario.
        
           | a_c wrote:
           | I feel you completely. The children brought me joy that no
           | way I can express how grateful I am. They made me realized
           | experience can only be, well, experienced. No amount of
           | describing can imprint the experience onto anyone. Now I
           | empathize much more with co-workers when they seem oblivious
           | to some solutions. Right now the children are asleep. I tried
           | to catch up some articles or to prototype some something. But
           | hey, no more focus juice left at all :)
        
         | [deleted]
        
       | joe_the_user wrote:
       | "...a challenging task: for example, watching letters appear on a
       | computer screen every 1.6 seconds and documenting when one
       | matched a letter that had appeared three letters ago."
       | 
       | It seems like they're conflating "stressful" and "thinking hard".
       | IE, Is this "thinking hard" or is it "maintaining constant
       | alertness"? I think things like staring at screen tax more than
       | the brain as such.
       | 
       | I spend most mornings working on math, programming and
       | philosophy. This doesn't make me feel tired. Neither does playing
       | the game of Go without a time limit. I assume all those tax the
       | brain itself. But Zoom call will absolutely make me feel tired
       | regardless of the subject.
       | 
       | And "stress" could cause a build-up of glutamate or whatever in
       | the brain also.
        
         | glial wrote:
         | They used the N-back task, a standard task used for inducing
         | mental effort (e.g. [1]). So in this case they has N=1 for the
         | easy group and N=3 for the hard group. Then they compared
         | glutamate concentration across groups.
         | 
         | I'm don't disagree that "thinking hard" is poorly defined. But
         | they did control for staring at a screen.
         | 
         | [1]
         | https://journals.plos.org/plosone/article?id=10.1371/journal...
        
       | IceMetalPunk wrote:
       | I'm now wondering what, if any, connection there is between
       | glutamate regulation and depression, since listlessness and
       | fatigue are common and characteristic symptoms. _To scientists:_
       | More research, please!
        
         | Phileosopher wrote:
         | I'm not scientific about it (n=1, after all), but I've realized
         | from my own diagnosis and coming out of it that depression is a
         | complex abstraction:
         | 
         | 1. Reactionary primary emotion (e.g., shock, surprise,
         | confusion)
         | 
         | 2. Add the perception of injustice to create the secondary
         | emotion of anger
         | 
         | 3. Have anger directed toward meeting an unmet need
         | 
         | 4. Give hopelessness about attaining that unmet need
         | 
         | 5. END IF nothing gives that hope to meet that need that the
         | anger was directed toward
         | 
         | edit: fayled at phormatting
        
           | IceMetalPunk wrote:
           | In my own struggles with depression, I can't really pinpoint
           | any anger/injustice most of the time. It's more just "anxiety
           | leads to inaction leads to ruined or missed opportunities
           | leads to insecurity and low self esteem leads to hopelessness
           | leads to 'why bother-ism'." Then again, my depression is
           | comorbid with an anxiety disorder, so perhaps it's different
           | from someone who has only the depression _shrug_
        
             | DiggyJohnson wrote:
             | Beautifully put. I think this is very interesting to
             | contrast with the also-well-put GP commenter. Different
             | flavors of sadness.
        
       | swayvil wrote:
       | Thinking is a bottomless pit for attention.
       | 
       | Put X attention into digging a hole and you get that much hole
       | dug.
       | 
       | Put X attention into sandwich-making and you get that many
       | sandwiches made.
       | 
       | But with thinking there's no real connection like that. You can
       | put a whole decade of attention into a bunch of thinking and
       | achieve zip.
       | 
       | It's an amazing attention sink. Whole mountains of attention can
       | disappear. Easily. Casually.
       | 
       | And then when you consider that many of us basically _think all
       | the time_. Habitually. Chewing over... memories and dreams and
       | plans and stuff. Woah!
       | 
       | And that attention is our energy budget. Flushed down the
       | thinkhole.
        
         | rzzzt wrote:
         | Can you go without thinking for an extended period of time? I
         | have split seconds here and there when I get the feeling I
         | haven't thought about anything for a while, only to interrupt
         | the streak with the very act of noticing.
        
           | swayvil wrote:
           | Yes I can. That's sorta what we do in this one meditation
           | technique called _vipassana_. I 've been doing it for a few
           | years.
           | 
           | When you get out of the habit of doing stuff with your
           | attention all the time (thinking etc) then your attention
           | moves in a new way. It sorta grows. It's pretty great.
        
       | georgeburdell wrote:
       | I didn't know this was a phenomenon. I have been thinking of hard
       | problems to fall asleep at night for years
        
         | CoastalCoder wrote:
         | Thanks for sharing that idea! I look forward to trying it out
         | tonight.
        
           | wizofaus wrote:
           | Sadly the more likely consequence is that you might fall
           | asleep quickly then wake up a few hours later and find
           | yourself still thinking about it, and that second time your
           | brain refuses to shut down until it solves it. Or maybe
           | that's just me.
        
         | keyle wrote:
         | I guess it works because you're not personally attached or
         | motivated at solving them.
         | 
         | So it comes down to counting sheep type of distraction.
         | 
         | Like others echoed, if you pick an open ended unsolved mystery
         | that is literally on your shoulders during the day, you'll be
         | unable to switch off.
        
         | odysseus wrote:
         | I have the opposite problem - if I'm thinking too hard near
         | bedtime about financial math or boolean algebra for example, I
         | won't be able to sleep. My brain is too active going through
         | all the calculations in my head.
         | 
         | If I want to fall asleep within 5 minutes, what works for me is
         | varied physical and mental exercise throughout the day, and an
         | easygoing book or movie near bedtime.
         | 
         | If there's something stressful going on the next day, a tech-
         | nerd podcast like ATP helps me forget about it and get to
         | sleep. But I try not to let late night podcasts become a habit
         | - sometimes they get too interesting and I stay up for over an
         | hour to keep listening.
        
           | georgeburdell wrote:
           | For me, it has to be really hard, not like some leftover work
           | you didn't do that day. The more open ended the better. For
           | example, how to make a transistor out of readily available
           | household components. How would you do lithography, doping,
           | etc.
        
             | plutonorm wrote:
             | Jesus, that line of thinking is a recipe to keep me up for
             | days. How you could even begin to fall asleep with a line
             | of thought so interesting is beyond me.
        
           | partiallypro wrote:
           | I'm the same way, I may become exhausted, I can feel myself
           | being exhausted by my mind won't let me sleep.
        
       | ravi-delia wrote:
       | See this is why I get annoyed at a body evolved for caloric
       | scarcity. We shouldn't get tired, we should get hungry! Oh,
       | pollutants build up in the brain? Burn more energy to get rid of
       | them! I should be able to strap an icepack to my head, fill a
       | bottle with olive oil, and overclock my brain to 10x speed.
        
         | tdaltonc wrote:
         | I don't think energy is the limiting factor here. A better
         | analogy would be with the limits of computability. Garbage
         | collection tasks are postposed to when we're asleep, but they
         | can only be put off for so long and there's a capacity for
         | "stuff to consolidate later" that fills up.
         | 
         | Something that you probably could get is a nob to control the
         | adaptability/efficiency setting on your brain. At the cast of
         | learning/remembering nothing, you could "execute" for longer.
         | We know that real brains make this trade off, but the
         | transition from one mode to the other is slow because it's
         | reactive.
        
           | radicaldreamer wrote:
           | Dolphins are better adapted to this as they can turn off half
           | their brain (and vice versa) while still functioning and
           | alert for up to 15 days straight.
           | 
           | Would be interesting if one day we could induce or evolve to
           | have similar capabilities.
           | 
           | https://www.smithsonianmag.com/smart-news/dolphins-sleep-
           | wit...
        
           | chundicus wrote:
           | > _Garbage collection tasks are postposed to when we 're
           | asleep, but they can only be put off for so long and there's
           | a capacity for "stuff to consolidate later" that fills up_
           | 
           | Do we have a strong reason to believe that? I know brain and
           | sleep mechanisms are tricky topics with lots of unknowns, but
           | I thought I had read research that showed sleeping brains
           | likely perform a chemical analogue to "garbage collection".
        
         | satyrnein wrote:
         | Only semi related, but i wanted to install a USB jack in my
         | belly button so i could charge my phone off my visceral fat,
         | which seemed like a win-win. Probably best I didn't, though,
         | because this predated usb-c...
        
         | sebastianconcpt wrote:
         | Hahaha that would be nice. But it likely demands a stock of
         | varied nutrients, not just "energy". Also the cells changing
         | need to take a break to consolidate what they have adapted to
         | (brain plasticity).
        
           | ravi-delia wrote:
           | > Also the cells changing need to take a break to consolidate
           | what they have adapted to (brain plasticity).
           | 
           | I feel like this has got to be a problem solvable by throwing
           | money at it. Not as is, most likely, but if we had evolved
           | without caloric restriction there would be some kind of more
           | complicated support structure which handles all that.
        
             | SketchySeaBeast wrote:
             | This feels like it may fall into the realm of "I think if
             | we just throw money at it we could solve it" problems that
             | you can't actually solve by throwing money at.
        
               | ravi-delia wrote:
               | Metaphorical money thrown at evolution several million
               | years ago, namely calories. You were built on a budget,
               | just because it's still better than anything we could
               | make doesn't mean it's the best evolution can do under
               | lesser constraints
        
             | mywacaday wrote:
             | If we had no calorie restriction why would we have evolved.
        
               | rNULLED wrote:
               | underrated perspective
        
         | AmericanChopper wrote:
         | You basically can do that. One of the limiting factors is your
         | ability to metabolise energy sources into energy your body can
         | use. Improve that by increasing your fitness and your cognitive
         | ability will be improved as well.
        
         | thaumasiotes wrote:
         | > See this is why I get annoyed at a body evolved for caloric
         | scarcity. We shouldn't get tired, we should get hungry! Oh,
         | pollutants build up in the brain? Burn more energy to get rid
         | of them! I should be able to strap an icepack to my head
         | 
         | Well, you did identify the major problem with the unlimited
         | overclocking plan. Burning more energy generates more heat. An
         | icepack on the side of your head doesn't solve the problem; at
         | some point your brain (and the rest of the inside of your head)
         | will cook, which is fatal.
        
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