[HN Gopher] Gut epithelial barrier damage caused by dishwasher d...
       ___________________________________________________________________
        
       Gut epithelial barrier damage caused by dishwasher detergents and
       rinse aids
        
       Author : miduil
       Score  : 93 points
       Date   : 2022-12-01 20:21 UTC (2 hours ago)
        
 (HTM) web link (www.jacionline.org)
 (TXT) w3m dump (www.jacionline.org)
        
       | Konohamaru wrote:
       | What is the solution? (Don't have the focus to read, understand,
       | and analyze the scientific paper atm.)
        
         | anon291 wrote:
         | Realistically, rinse aid is hardly necessary.
        
         | ketralnis wrote:
         | The trouble isn't the solution so much as the precipitate
        
       | sramsay wrote:
       | The real news here is that there is such a thing as a "gut-on-a-
       | chip."
        
       | wobbly_bush wrote:
       | Is my reading of the summary correct that it is only (or mainly?)
       | talking about rinse aid and not about the detergent?
        
         | ars wrote:
         | Yah, it seemed the same to me.
         | 
         | I don't use rinse aid, never have, you don't actually need it,
         | you can just let the dishes air dry for slightly longer.
         | 
         | If you have hard water then soften it, rather than use a rinse
         | aid.
        
           | matthewdgreen wrote:
           | It is talking about professional dishwashers like the ones
           | used in restaurants. So if you dine out on a regular basis
           | you're probably getting exposed to this stuff even if you
           | don't use it at home.
           | 
           | PS I have no chemical expertise, but the article singles out
           | alcohol ethoxylates as the cause of this damage. And while I
           | don't use rinse aid in my home dishwasher, my Cascade
           | dishwasher pods list "Isotridecanol Ethoxylated" as an
           | ingredient, which may be one of these substances? At least
           | this gets rinsed off, though I doubt it gets rinsed
           | completely.
        
             | Bud wrote:
        
             | quercusa wrote:
             | If I remember chem class correctly, -nol indicates an
             | alcohol (ethanol, methanol...)
        
             | kwhitefoot wrote:
             | Many years ago I worked as a skivvy in a hotel kitchen. We
             | never used any detergent for the crockery, it just used
             | extremely hot water. The dishes seemed very clean and they
             | dried very rapidly.
        
               | SoftTalker wrote:
               | Yep. If the water is hot enough you don't need chemical
               | detergent or sanitizer. But we're talking about water
               | that is almost boiling -- you'd only find dishwashers
               | that hot in a commercial kitchen.
        
               | giraffe_lady wrote:
               | How... many... years ago? When I started cooking
               | professionally in the 80s three-stage hand wash had
               | already been required by health codes everywhere for
               | decades. I've seen all kinds of shit but every kitchen at
               | least _has_ the setup and chemicals for that for health
               | inspections if nothing else. In practice even the
               | sketchiest restaurants will have quats even if they only
               | fill it once a day.
        
               | SoftTalker wrote:
               | GP is talking about a commercial dishwasher. You can't
               | hand wash hot enough -- you'd get serious burns. So
               | anything you hand wash needs the three-stage wash, rinse,
               | sanitize process with detergent and chemical sanitizer.
        
             | jandrese wrote:
             | If the purpose of the substance is to make the dishes dry
             | faster it makes sense that it would not be fully rinsed off
             | at the end of the cycle. In theory you would hope that they
             | would evaporate off of the dishes, but that leads to air
             | quality issues, so all in all these rinse aids seem
             | problematic.
        
         | hammock wrote:
         | Rinse aid and detergent both have the same active, harmful
         | ingredient: sulfates aka AES aka surfactants. The difference is
         | that detergent gets rinsed off, while rinse aid IS the rinse
         | (vs plain non-aided water).
        
       | magila wrote:
       | I suffered from chronic diarrhea for years which I attributed to
       | Crohn's disease. This seemed obvious since diarrhea is a very
       | common symptom of Crohn's, but its onset had been several years
       | after I was diagnosed and prior to that I had tended more towards
       | the opposite problem (constipation). I was thus always suspicious
       | that the root cause lay elsewhere. After much experimenting I
       | found that if I ran my dishwasher through an extra rinse cycle
       | the diarrhea went away.
       | 
       | I tried many different detergents but never found one which
       | didn't cause problems, so I've just continued to run an extra
       | cycle. My GI doctor didn't really believe me when I told him. I
       | wonder how many people are having their IBS/IBD symptoms
       | exasperated by detergent residue left on their dishes.
        
       | iLoveOncall wrote:
       | Wait, people were serious when they said we shouldn't eat Tide
       | Pods?
        
       | trebor wrote:
       | Ironically, the summary isn't as good as the "Key Messages"
       | section at the bottom:
       | 
       | > * Professional dishwasher rinse aid causes cellular
       | cytotoxicity and directly impaired barrier integrity of gut
       | epithelial cells by damaging TJ and AJ expressions in daily
       | exposed concentrations. > * The underlying mechanisms of
       | epithelial barrier disruption in response to rinse aid were cell
       | death in 1:10,000 dilutions and epithelial barrier opening in
       | 1:40,000 dilutions. > * The alcohol ethoxylates, an ingredient of
       | the rinse aid that remains on washed dishware, caused the gut
       | epithelial inflammation and barrier damage.
       | 
       | It appears to be the rinse aid when used in professional
       | dishwashers utilized in restaurants, etc, due to high
       | concentration of the rinse aid contaminating the "clean" dishes.
        
         | giraffe_lady wrote:
         | Yeah in industry they are often called sanitizers because the
         | purpose and mechanism are fundamentally different from the home
         | ones people are familiar with. Or as a common chef quip: "the
         | dishwasher is the guy running it, the machine is a sanitizer."
         | 
         | They are notoriously bad at removing food residue, which must
         | be sprayed or scraped off before running. Anything more than
         | trace is cooked onto the dishes. They're really good at
         | removing thin layers of grease quickly, and sanitizing. Doesn't
         | surprise me at all that they don't do a final rinse; handling
         | stuff right out of them leaves a distinct feeling on your
         | fingers, like the opposite of bleach kinda. You have more
         | friction than you should until they fully dry, it's very
         | noticeable.
        
         | jasonhansel wrote:
         | Importantly, when they tested a household dishwasher, they
         | didn't find the same issues:
         | 
         | > In contrast, the residual substances on the cups washed in a
         | household dishwasher with detergent B were not present at
         | sufficiently high concentrations to exert cytotoxicity and
         | impair the epithelial barrier function (see Fig E9).
        
           | JonathonW wrote:
           | Also, they've only tested one professional dishwasher and one
           | household dishwasher using one specific formulation of rinse
           | aid.
           | 
           | There's enough here to indicate a need for further
           | investigation, but not enough data to come to any overall
           | conclusions about commercial or household dishwasher safety
           | in general.
        
           | hammock wrote:
           | If you use a rinse aid in your dishwasher I bet you'd find
           | harmful results.
           | 
           | Home detergent does contain AES (sulfates) but it gets rinsed
           | pretty well. However if you use rinse aid, the rinse water
           | itself has surfactants (AES, more sulfates), which will
           | remain on the dishware- that's the whole point actually, so
           | the water beads off.
        
             | SoftTalker wrote:
             | The rinse aid prevents beading, actually. Beading is what
             | leaves the spots.
        
               | hammock wrote:
               | Yes I had it backwards. It's the old "add soap to water
               | to break the surface tension" kids science experiment:
               | https://youtu.be/ho0o7H6dXSU
        
             | joezydeco wrote:
             | One of the most popular brands in the US, Jet Dry, has the
             | ethoxylated alcohol mentioned in the article:
             | 
             | http://www.rbnainfo.com/MSDS/CA/FINISH%20-%20JET-
             | DRY%20Rinse...
        
       | [deleted]
        
       | b20000 wrote:
       | So what does this mean for all of us who buy coffee at coffee
       | shops every morning? Will this cause serious problems long term
       | since we are consuming residues of their dishwasher chemicals?
       | One potential solution is to always get your coffee to go, but
       | that probably only partly solves the problem.
        
         | gadflyinyoureye wrote:
         | Oh I bet that is a frying pan fire thing. The cups are probably
         | endocrine disrupters too with a plastic lining.
        
           | hammock wrote:
           | Hot beverage cups are coated with polyethylene which is one
           | of the most inert polymers you can get. You could do much
           | worse.
        
         | hammock wrote:
         | What are you getting from a coffee shop that has been through a
         | dishwasher? The mug?
        
         | Karawebnetwork wrote:
         | There are a lot of things than can go wrong when you order from
         | a restaurant or coffee shop. There could be diseases, bacteria,
         | virus, chemicals or even contaminent such as glass parts or
         | insects. The answer to this question would be to only order
         | from places you trust - and even then, contamination can happen
         | quickly and in invisible ways.
        
           | lazide wrote:
           | As anyone who has worked the back of a kitchen can attest,
           | there are almost no actually trustworthy restaurants.
        
             | bbarnett wrote:
             | I've worked in several, and if you mean "infallible" OK,
             | but I can assure you the people I worked with gave a damn,
             | cared, and would never intentionally slack off, or do a
             | poor job, placing people at risk.
             | 
             | Maybe you just worked with/for terrible people?
        
               | xeromal wrote:
               | One of the dirtiest, worst people I know is a sous chef
               | at Flemings. Take that for what you will.
        
       | doitLP wrote:
       | It's time to place all chemicals in the "unsafe until proven
       | safe" category.
        
       | fire wrote:
       | huh, I didn't know home and commercial rinse aids were any
       | different?
        
         | skrbjc wrote:
         | Based on the paper it seems to be primarily an issue with
         | dilution. They say home dishwashers dilute it to a rate of
         | around 1:80000, the commercials ones are around 1:1000 -
         | 1:10000. The problems they observed seem to happen in that
         | lower dilution range.
        
       | blackhaz wrote:
       | How to recognize an alcohol ethoxylate?
        
         | hammock wrote:
         | Anything that ends in "sulfate" on the ingredients label. Or
         | anything that is labeled "detergent" or "rinse aid."
        
       | awinter-py wrote:
       | wonder how the proliferation of small motors + robots will affect
       | the use of chemicals in applications like this
       | 
       | better robotics tech can reduce chemical use by:
       | 
       | 1. spot application of sponge in place of general application of
       | chemicals
       | 
       | 2. more targeted application of chemicals (only when + where
       | needed)
       | 
       | 3. replacing poison for pest / weed elimination with smart mobile
       | traps (have seen laser POCs for both bugs + weeds)
       | 
       | 4. cleaning materials for recycling using targeted friction
       | instead of soap. separating oil and food scraps from drain water.
       | separating human waste from gray water (and selling the nitrates)
       | 
       | even for something innocuous like brushing your teeth, a robot
       | can use advanced sensing to modify the dose of fluoride
       | 
       | feels like lots of 'bits to atoms' projects here for someone who
       | enjoys garbage
        
       | blockwriter wrote:
       | It's endocrine awareness day on Hacker News
       | (https://news.ycombinator.com/item?id=33816861)
        
         | jasonhansel wrote:
         | I don't think the OP proposes an endocrine-related mechanism
         | for this damage.
        
       | hokkos wrote:
       | I use white vinegar instead of a dedicated rinse aids.
        
       | boomchinolo78 wrote:
       | Oh wait....cue gluten-allergy
        
         | merth wrote:
         | I think I have gluten-sensitivity(cant confirm). I rarely eat
         | out. always order delivery, use plastic fork. I dont have a
         | dish washer.
        
       | jliptzin wrote:
       | What the hell is rinse aid anyway
        
         | hammock wrote:
         | It's just surfactants. Aka detergent. That doesn't get rinsed
         | off, it gets "rinsed on." It's function is to make water bead
         | off the glass so that water spots are not left
        
           | derbOac wrote:
           | Dishes also dry off faster as water beads off more.
        
         | ironmagma wrote:
         | Useless liquid you put in your modern dishwasher which doesn't
         | perform a proper drying to save energy.
        
         | jandrese wrote:
         | Residential version is marketed under the trademark "Jet Dry".
         | It's intended to prevent hard water spots on your dishes, but
         | most people don't care enough or don't have this problem so
         | it's not heavily used.
        
         | jasonhansel wrote:
         | It's a special liquid you put in a compartment in your
         | dishwasher to make it work better.
         | 
         | I don't bother; I've tried it and haven't observed any effects.
        
           | xxpor wrote:
           | It really depends on if you have a dishwasher that relies on
           | evap for drying, or an explicit heating element. The latter
           | is becoming more rare as time goes on.
        
             | lotsofpulp wrote:
             | How would dishes dry then? Is there at least a fan
             | providing air flow?
        
               | xxpor wrote:
               | This is why rinse aid is critical, you have to minimize
               | the amount of water on the dishes. The extremely hot
               | water tends to heat up the dishes enough so they retain
               | enough heat to evaporate off the rest of the water.
               | Plastic stuff like cups tends to stay pretty wet since
               | they don't have the thermal capacity of metal or
               | porcelain. A big advantage with this design, other than
               | the energy savings, is that you don't have to worry about
               | putting plastic stuff on the bottom rack, since there's
               | no localized source of heat that can melt them.
        
       | RjQoLCOSwiIKfpm wrote:
       | Rinse aid is completely unneeded if you properly maintain and use
       | your dishwasher.
       | 
       | I never use any, and my dishes are completely spotless. 30 years
       | old dishwasher, super hard water.
       | 
       | Specifically, you should:
       | 
       | - always fill the salt of the dishwasher's water softener once
       | it's empty. It cannot soften the water if it doesn't get cleaned
       | by the salt. If the water is not softened you will get spots.
       | EDIT: Apparently US folks often have dishwashers which don't
       | soften the water. Ugh. In Europe I haven't even heard that such a
       | thing exists! :|
       | 
       | - configure the dishwasher to your water hardness.
       | 
       | - do NOT use detergent which is advertised as "you won't need
       | salt". This is garbage for lazy people. It cannot properly
       | replace the water softener. Think about it for a moment: The
       | detergent is meant to fully dissolve during washing so you won't
       | have it on your dishes after the final water cycle. The only way
       | it could affect the softness of the water in the final cycle is
       | if it did NOT fully dissolve in time. So there are two factors to
       | be optimized which contradict - stay long enough to soften the
       | water, but not long enough to leave remainders on the dishes. It
       | will never work properly.
       | 
       | - This is not related to rinse aid, but you should know it: Clean
       | the sieve regularly, at least every week. It will get ultra nasty
       | with gunk if you don't. If you have no time for cleaning it, buy
       | a second one, switch them once one is dirty and put it among the
       | dishes so the dishwasher washes it like a dish.
        
         | casion wrote:
         | Fill the salt? Configure for water hardness?
         | 
         | I've never heard of either of these things before. Certainly
         | not things on my, relatively fancy, dishwasher.
        
           | quantified wrote:
           | US consumers are easier to sell to, perhaps.
        
           | teekert wrote:
           | I've never seen a dishwasher without this :)
           | 
           | But I think most people here in the Netherlands never set it
           | up correctly and go for "all in 1" tabs. I never do, always
           | set it up correctly. I do feel I need rinse aid to not have
           | that nasty feel to the glasses.
        
           | RjQoLCOSwiIKfpm wrote:
           | https://en.wikipedia.org/wiki/Dishwasher_salt
           | 
           | The water hardness setting determines how much the water
           | softener tries to soften the water.
           | 
           | If the water isn't soft enough, it will leave spots on the
           | dishes. Hence people use "rinse aid", so the improperly
           | softened water would drip off before it leaves spots.
           | 
           | If the water is properly softened it contains no calcium etc.
           | which could cause spots on your dishes.
        
           | yamtaddle wrote:
           | Ditto, no clue what either of those mean. Never, ever heard
           | of adding salt to a dishwasher, certainly. Not in new ones,
           | not in ones from the bad ol' days when they used way more
           | water but actually worked.
        
             | djpr wrote:
             | I have a new one (a few years old) and yes there's a
             | compartment for salt. My previous one did as well. I'm in
             | Europe (Spain) if that helps. I don't go to any special
             | store to buy them, any old Lidl or other supermarket has
             | it. Where you from where this isn't a thing?
        
         | jasonhansel wrote:
         | My dishwasher doesn't have a salt compartment or any sort of
         | water-softening features; in the US, I haven't heard about this
         | feature. Apparently it's a UK thing?
        
           | denimnerd42 wrote:
           | I know Miele has a water softener feature. That's the only
           | time I've heard of it in the US.
        
             | pdq wrote:
             | There are a few Bosch models with dishwasher salt
             | dispensers, but it's extremely rare in the US.
             | 
             | It's a great idea, given most municipalities have hard
             | water.
        
               | swader999 wrote:
               | Yeah I need it with my well water. But generally we just
               | put up with spotty dinnerware. If we have guests over,
               | we'll wash whatever by hand before.
        
         | mauvehaus wrote:
         | Fill the salt? I'm not sure all dishwashers have a receptacle
         | for that. Ours doesn't, and I'm pretty confident that I've
         | never had one that did across several states in the US and one
         | place in Belgium.
         | 
         | Is the salt for doing a softening process that substitutes for
         | a whole house softener if you don't have one?
         | 
         | We live in a place with hard water and have no softener in the
         | house (you should see our electric kettle when we haven't
         | cleaned it recently). Recently the accumulation of what I
         | assume to be mineral film has gotten a bit noticeable on the
         | dishes that go in the dishwasher.
        
           | cj wrote:
           | My dishwasher has a "salt" light that lights up when the salt
           | is low.
           | 
           | The dishwasher is also 30 years old. Miele G 680 SC from
           | 1992. Living in New York. Perhaps adding salt was more common
           | in older models.
        
         | [deleted]
        
         | codetrotter wrote:
         | > Apparently US folks often have dishwashers which don't soften
         | the water. Ugh. In Europe I haven't even heard that such a
         | thing exists!
         | 
         | I've only come across this in Spain so far. Never seen in
         | Norway. But maybe I just haven't been paying attention. Then
         | again, the water in Norway in :chefskiss:
        
         | PragmaticPulp wrote:
         | For everyone confused by this comment: In some countries you
         | might find dishwashers with a sort of built-in water softener:
         | https://en.wikipedia.org/wiki/Dishwasher_salt
         | 
         | It's not common in the United States. Some all-in-one detergent
         | packets might contain some amount of dishwasher salt, though.
        
           | cvoss wrote:
           | In my limited experience in the several places I've lived in
           | the US, only one had an issue with water that was hard enough
           | to need addressing. Most residences there had a dedicated
           | household water softener, so even there the dishwashers
           | didn't need to do their own softening.
           | 
           | Here's a nice map [1]
           | 
           | [1] https://homewater101.com/articles/hard-water-across-us
        
           | mauvehaus wrote:
           | I'll give you an upvote for that little dive into Wikipedia.
           | For those who haven't already swum as deep, the article on
           | ion exchange resins[0] is also worthwhile. Turns out they are
           | used for reprocessing spent nuclear fuel as well as softening
           | water. Plus a few other things.
           | 
           | [0] https://en.m.wikipedia.org/wiki/Ion-exchange_resin
        
             | DwnVoteHoneyPot wrote:
             | I did bad in high school chemistry, I never could
             | understand this stuff. First, the ion exchange resin beads
             | are washed with Na+ which bind to the beads. Second, the
             | hard water is run through the beads and bad stuff like Mg2+
             | has a stronger attraction to the beads than Na+, so the Na+
             | is pushed off and Mg2+ binds to beads. The resulting water
             | out of tap is softer because Mg2+ is out, but saltier
             | because Na+ is in. Then once in a while the beads are
             | flushed with Na+ again with the Mg2+ being sent down the
             | drain... but how does this happen if Na+ has a weaker bond?
             | How can it push the Mg2+ off the beads??
        
           | throwaway09223 wrote:
           | "It's not common in the United States."
           | 
           | If US folks are looking for this feature, it can be found on
           | higher end Bosch dishwashers in the US.
           | 
           | I have very hard water and a Bosch benchmark series. The
           | water softener makes a _huge_ difference. I don 't want a
           | whole-house softener because I don't enjoy the feel of
           | softened water in the shower.
        
         | jiveturkey wrote:
         | > - always fill the salt.
         | 
         | rinse aid is for hard water. restaurants probably tend to not
         | treat the water and the commercial dishwashers they use
         | probably tend to not have a provision for salt. they operate
         | very differently than your residential dishwasher.
         | 
         | So yes, completely unneeded if you have soft water. Most
         | dishwashers don't have a provision for salt.
         | 
         | Also completely unneeded if you don't mind spots.
        
           | literalAardvark wrote:
           | I have hard water and a dishwasher with a softener. The
           | plates are dramatically cleaner if there's salt in the
           | softener, no matter what detergent i use.
        
       | johndoughy wrote:
       | > our results suggest that alcohol ethoxylates were the main
       | culprit component of the rinse aid responsible for the observed
       | toxicity and damage to the epithelial barrier integrity.
        
       | aaron695 wrote:
        
       | seydor wrote:
       | maybe dont wash them that often
        
         | wutheringh wrote:
         | I know a guy who washed his dishes, and he died
        
           | merth wrote:
           | I know a guy, who has 20 pans and all dirty, washes no 19 to
           | cook his 2$ stake. what a legand.
        
             | zgin4679 wrote:
             | You'd think the stakes couldn't get any higher!
        
           | PainfullyNormal wrote:
           | True story!
        
           | zgin4679 wrote:
           | I knew Bill, too. Good man, clean dishes. RIP, Bill.
        
         | WillPostForFood wrote:
         | You should start a business: a restaurant that serves your food
         | on the previous diner's unwashed dishes.
         | 
         | It would be like my college apartment kitchen, so you could
         | hire me as manager.
        
           | seydor wrote:
           | The Healthy Gut Epithelium Restaurant*.
           | 
           | *you might die of other causes, though
        
         | jasonhansel wrote:
         | You just need to buy the special "no-wash" dishes.
        
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       (page generated 2022-12-01 23:00 UTC)