[HN Gopher] E-bandages lightly zap and heal wounds
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       E-bandages lightly zap and heal wounds
        
       Author : gmays
       Score  : 79 points
       Date   : 2023-03-07 20:23 UTC (1 days ago)
        
 (HTM) web link (spectrum.ieee.org)
 (TXT) w3m dump (spectrum.ieee.org)
        
       | jtbayly wrote:
       | Would my body absorbing this metal be detrimental to my health in
       | other ways?
        
         | pacaro wrote:
         | AFAICT recommended max daily dose of molybdenum is 2mg per day.
         | Above that it starts to get pretty nasty
        
         | amalcon wrote:
         | There are a lot of metals in your diet. Iron and sodium are
         | most famous, but others are present too. You need a little of
         | most of them, but too much can be toxic. Probably there's a lot
         | in this thing; it's not clear from the article if it's enough
         | to cause a problem.
        
         | jws wrote:
         | The study, https://www.science.org/doi/10.1126/sciadv.ade4687
         | suggests in figure 1 that the device is 0.5mg of molybdenum and
         | dissolves over an 18 day period, ~30ug/day. This is less than
         | your recommended dietary allowance of 45ug/day and about two
         | orders of magnitude under the tolerable upper intake level.
         | 
         | You will also find in the study analysis of what compounds the
         | molybdenum forms as it dissolves.
         | 
         | Also, who knew they were supposed to be getting molybdenum
         | every day? Somehow I feel a bit more cyborgy now, like maybe
         | there is a tiny gear in me somewhere that needs to be greased.
        
           | [deleted]
        
         | hammock wrote:
         | Acute toxicity of molybdenum (Mo), the metal in question, has
         | not been seen in humans, and the toxicity depends strongly on
         | the chemical state.
         | 
         | Studies on rats show a median lethal dose (LD50) as low as 180
         | mg/kg for some Mo compounds.
         | 
         | Although human toxicity data is unavailable, animal studies
         | have shown that chronic ingestion of more than 10 mg/day of
         | molybdenum can cause diarrhea, growth retardation, infertility,
         | low birth weight, and gout; it can also affect the lungs,
         | kidneys, and liver
        
           | moffkalast wrote:
           | I'm no doctor, but that does sound rather unpleasant.
        
           | Someone wrote:
           | 180mg/kg is 10 grams for a 55 kg (=fairly lightweight) human.
           | 
           | Also, 10mg/day in which animals? I would guess animals that
           | are a lot smaller than humans, possibly even mice (weight:
           | less than 1/1000 of that of a human)
        
         | BelleOfTheBall wrote:
         | I imagine a tiny amount would be okay, based on the scientists'
         | reactions. However, I wonder if chronic use of this, which is
         | how it'd be for diabetics, would actually lead to bad
         | consequences. Perhaps the material is specifically tailored to
         | be not just prone to absorption but also neutral/positive when
         | processed by the body?
        
         | gpm wrote:
         | There's a lot of medical technology that involves sticking
         | metal inside of people _permanently_ , as long as they're
         | making it out of the right kind of metal it's hard to believe
         | it would be an issue to stick it on your skin.
        
           | capitainenemo wrote:
           | The article notes it doesn't just sit on your skin, but is
           | designed to break down and be absorbed as the wound heals. So
           | the amount of metal is a legit concern.
        
           | doubled112 wrote:
           | And they always get it right, like cobalt in hip
           | replacements.
        
           | dharmab wrote:
           | I once dissected a titanium knee replacement that had been
           | implanted in a human. The surrounding tissue was steel-grey
           | from metallosis.
        
             | pengaru wrote:
             | Isn't that a unique property of titanium and part of _why_
             | it 's chosen for skeletal implants?
             | 
             | When a buddy got a damaged tooth replaced with an implant,
             | he showed me medical scans of the titanium rod in-situ with
             | the surrounding bone highlighted as growing into the rod as
             | if they had an affinity for one another. It was part of a
             | document explaining the safety and why titanium was chosen,
             | how the body doesn't reject the material as foreign etc.
        
             | yamazakiwi wrote:
             | My mother had a metal mesh implant for a knee injury in the
             | 70's and later had to have it extracted and her entire knee
             | replaced.
        
           | lapetitejort wrote:
           | I have metal in my body planted without my consent via an
           | explosive device and the doctors don't care to take it out.
           | The risk of infection outweighs the risk of it staying in my
           | body.
        
           | [deleted]
        
       | unsupp0rted wrote:
       | I wondered why electricity would help a wound heal in the first
       | place.
       | 
       | > The inflammation associated with these wounds can disrupt the
       | body's normal electric signals, impeding the migration of new
       | cells that can support the healing process.
        
         | sva_ wrote:
         | Reminds me a bit of Michael Levin's work, where they use
         | electrical signals to cause organisms to regrow limbs.
        
         | slackdog wrote:
         | I suppose it's probably an unrelated effect, but electron beams
         | are often used for sterilizing things like food, medical
         | packaging, etc.
         | 
         | https://en.wikipedia.org/wiki/Electron-beam_processing
         | 
         | https://en.wikipedia.org/wiki/Food_irradiation#Electron_beam
        
         | psychphysic wrote:
         | Honestly, that is indistinguishable from the crystal mumbojumbo
         | you get. And it feels like we're at the magic/science interface
         | with electrotherapy.
         | 
         | That said it is somewhat suspect, and the hypothesis is not
         | really falsifiable by the experiment which is why the journal
         | article itself is not claiming to test that. It is really
         | disappointing that IEEE didn't actually link to or name the
         | article directly. Very poor science journalism there.
         | 
         | The article is that they observed this process working, not why
         | it works. Maybe it works because it kills bacteria...?
        
           | iandanforth wrote:
           | Nope ion concentration gradients (which also manifest as
           | electrical potentials) serve to guide everything from white
           | blood cells to the precursors of both replacement and scar
           | tissue. You can mimic this signal directly by applying a
           | potential difference.
           | 
           | https://www.sciencedirect.com/science/article/abs/pii/S10849.
           | ..
        
         | LegitShady wrote:
         | your cells are sensitive to charge in general - cells attempt
         | to maintain certain voltage differentials across their
         | membranes via ion channels in the cell membrane, can
         | communicate voltage information with each other via gap
         | junctions, etc. That electrical communication does control how
         | cells behave.
         | 
         | If you have 20 minutes to watch this ted talk interview I
         | highly recommend it. My mind was blown. Your DNA determines the
         | hardware, but there's a lot of non chemical communication that
         | goes on between cells that determine how they behave.
         | 
         | https://www.youtube.com/watch?v=XheAMrS8Q1c
         | 
         | Once you realize that cells can effectively communicate with
         | each other via voltage, things like whats described about
         | electrical bandages become less surprising.
         | 
         | If you've got a little more time (2 hours) there's a much
         | longer more detailed interview here:
         | 
         | https://www.youtube.com/watch?v=Z0TNfysTazc
         | 
         | This is some next level stuff. Imagine DNA describes what your
         | hardware looks like, but the software your cells run may be
         | bioelectrical in large enough ways to consider that maybe your
         | skin has some level cognition.
        
       | jongjong wrote:
       | This sounds cool but its usefulness seems limited.
        
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