[HN Gopher] Notice of Intent to Amend the Prescription Drug List... ___________________________________________________________________ Notice of Intent to Amend the Prescription Drug List: Vitamin D (2020) Author : walterbell Score : 34 points Date : 2023-06-21 20:38 UTC (2 hours ago) (HTM) web link (www.canada.ca) (TXT) w3m dump (www.canada.ca) | pazimzadeh wrote: | Reminder that taking Vitamin D in excess without having enough | Vitamin K could lead to vascular calcification, whereas | sufficient levels of Vitamin K promotes proper absorption of | calcium into bones. | | Vitamin K supplementation for the primary prevention of | osteoporotic fractures: is it cost-effective and is future | research warranted? https://pubmed.ncbi.nlm.nih.gov/22398856/ | | Matrix Gla protein is an independent predictor of both intimal | and medial vascular calcification in chronic kidney disease | https://www.nature.com/articles/s41598-020-63013-8 | | Matrix Gla protein | https://en.wikipedia.org/wiki/Matrix_Gla_protein | flenserboy wrote: | Don't forget magnesium. | cies wrote: | I like to refer to Greger (a meta-study researcher in nutrition | field): | | https://nutritionfacts.org/video/the-purported-benefits-of-v... | | His conclusion on VitK: eat your greens. | sBqQu3U0wH wrote: | Recent studies suggest that taking vitamin K supplements does | not help to prevent calcium build up in heart valve. | | https://www.heart.org/en/news/2022/04/25/despite-hopes-vitam... | snapplebobapple wrote: | I don't believe they controlled for vitamin D status. The | line has always been you need k and d in sufficient levels to | get calcium to the right place so I'm not surprised that one | or the other causes problems (although I do really want to | see someone redo this with people with clinically validated | moderate vitamin d levels). | mtalantikite wrote: | What's considered excess for Vitamin D? | cies wrote: | Strange how doctors I follow tell me that in winter months I'd | need 2000IU per day of VitD it needed for my latitude/ sun | exposure/ skin color. While the recommended daily intake is about | 10x lower, so low that it may even be too low to measure the | benefits. Are those FDA-like institutes so slow? | chrismeller wrote: | Umm... yes, yes they are. | cies wrote: | I know, where I live milk is still promoted by such | institutes. We know for 40+ years it's bad for health beyond | the weaning stage or near starvation. | serallak wrote: | Can you elaborate on that? | fmajid wrote: | It's utter nonsense, unless you are lactose intolerant. | The mutation that allowed adults to digest milk had such | a high fitness value it spread from Scandinavia through | the human population like wildfire by evolutionary | standards. | | https://en.wikipedia.org/wiki/Lactase_persistence | bluGill wrote: | About 1/3 of adult humans can digest milk. For the | majority it is harmful. However the other third have | evolved to digest milk as adults and it isn't harmful in | the same way. | | It is an intersting coincidence that ability to digest | milk as an adult and fluency in English are correlated. | chiefalchemist wrote: | Consider this...Milk is intended to feed baby cows. | Humans are not cows. Some cows milk for humans is likely | not harmful. But beyond that you're ingesting a cocktail | of nutrients and hormones intend for a baby cow. | | Put another way, just because Big Milk has normalized | doesn't mean it's a good dietary decision. | | Proceed at your own risk. | chrisco255 wrote: | Milk is one of the healthiest foods you can eat. It is a | complete food, meaning it has all essential nutrients for | human nutrition, including protein, fat, carbs, essential | vitamins and minerals. If you had to pick a single food to | live off for the rest of your life, milk would definitely | be in the top 3. | jstarfish wrote: | What are the other 2? | ASalazarMX wrote: | If milk was that bad, humans wouldn't have developed adult | lactose tolerance 10K years ago. Being able to drink/eat | milk and dairy products was clearly an advantageous | adaptation because it became very widespread mutation. | | https://www.smithsonianmag.com/arts-culture/lactose- | toleranc... | AdamH12113 wrote: | If I read this right, they're increasing the maximum non- | prescription dose of vitamin D from 1000 IU/day to 2500 IU/day. | This seems to be the official dose on the label; nothing prevents | you from taking extra pills. There's some discussion of | methodology; the new limit seems to be a maximum known-safe | dosage for someone in the 95th percentile of vitamin D intake. | There's a fairly large safety margin built into these numbers for | risk tolerance. | treeman79 wrote: | I had horrific migraines. Would walk into a store, and the | lights would leave me completely dysfunctional within 10 | minutes. Tons of triggers. Spent 18-20 hours a day in bed | unable to function. | | After about a year of 3000u daily vitamin D, my migraines were | mostly gone. Lights and most other triggers didn't bother me at | all. | | I did get tested at beginning and levels were quite low. | lesquivemeau wrote: | What is your point ? I don't doubt your story but how is it | relevant ? There is no established causation here | cubefox wrote: | https://xkcd.com/552/ | vladd wrote: | Why think in binary? His anecdote can be inspirational for | others and testing his correlation is cheap to try out for | others in similar predicaments. | chrismeller wrote: | > The UL itself was set by adjusting for uncertainty from a "no | observed adverse effect level" intake value of 10,000 IU (250 | ug)/day. | | That's a very large safety margin. | SeanLuke wrote: | This seems to be a lot of text to avoid saying "we made a huge | statistical error". | cies wrote: | And we know this already for 10+ years. ___________________________________________________________________ (page generated 2023-06-21 23:01 UTC)