[HN Gopher] Aspartame sweetener to be declared possible cancer r...
       ___________________________________________________________________
        
       Aspartame sweetener to be declared possible cancer risk by WHO, say
       reports
        
       Author : sandebert
       Score  : 128 points
       Date   : 2023-06-29 13:16 UTC (9 hours ago)
        
 (HTM) web link (www.theguardian.com)
 (TXT) w3m dump (www.theguardian.com)
        
       | miika wrote:
       | Mobile phones, WiFi etc a have been under the same classification
       | by WHO since 2011. The industry didn't take it too seriously, and
       | probably this one doesn't mean anything either.
       | 
       | https://www.iarc.who.int/wp-content/uploads/2018/07/pr208_E....
        
       | shrubble wrote:
       | Donald Rumsfeld was famously influential in getting aspartame's
       | approval ; however more of the story behind this can be found
       | here:
       | https://dash.harvard.edu/bitstream/handle/1/8846759/Nill,_As...
       | 
       | In 1984 the year after aspartame's approval for soft drinks, the
       | company that held the exclusive patent on it, sold $600 million
       | worth (1984 dollars) of it.
       | 
       | Myself the truly distasteful part is the use of neotame (a
       | follow-on to aspartame) on animal feed, to get animals to eat
       | feed that they normally would not; for instance, if the feed is
       | rancid or otherwise in a condition/taste that normal animal
       | instincts, would have the animal reject the food...
        
         | iLoveOncall wrote:
         | > Myself the truly distasteful part is the use of neotame (a
         | follow-on to aspartame) on animal feed, to get animals to eat
         | feed that they normally would not; for instance, if the feed is
         | rancid or otherwise in a condition/taste that normal animal
         | instincts, would have the animal reject the food...
         | 
         | What's the difference between that and humans eating a pizza
         | but not eating the raw ingredients of a pizza? If it's not
         | inedible anymore I don't see the issue...
        
         | cameldrv wrote:
         | > Myself the truly distasteful part is the use of neotame (a
         | follow-on to aspartame) on animal feed, to get animals to eat
         | feed that they normally would not; for instance, if the feed is
         | rancid or otherwise in a condition/taste that normal animal
         | instincts, would have the animal reject the food...
         | 
         | True for human food as well. Maybe it's not rancid, but food
         | science can make terrible ingredients taste great. Take
         | Doritos. It's just cornmeal (animal feed) plus a ton of
         | artificial flavoring that is incredibly well dialed in to make
         | them delicious and even addictive.
        
           | Waterluvian wrote:
           | Or HP sauce.
           | 
           | Honestly I see it as a feature if we can move product that's
           | otherwise garbage, as long as it's not dangerous. Reminds me
           | of "omg do you know what's in hotdogs?!" Hotdogs are a
           | success story.
        
           | rightbyte wrote:
           | Cornmeal is just corn flour but with courser grinding? But
           | glutamate and stuff, sure. Doritos have the same "fake" feel
           | as Pringles according to my taste.
        
           | SketchySeaBeast wrote:
           | I think it's disingenuous to say that cornmeal is just animal
           | feed. Polenta has been a thing for a long time.
        
             | IshKebab wrote:
             | Yeah that's like saying "sandwiches are just ground up
             | wheat, plus a ton of delicious filling to make them taste
             | good"
        
               | nielsbot wrote:
               | Not quite--I assume sandwich fillings are food. Doritos
               | are coated w flavor powder.
        
               | xormapmap wrote:
               | Most bread you get from a supermarket (even outside the
               | US) is highly processed garbage, as are many common
               | sandwich fillings (mayo, salami, margarine). The typical
               | sandwich is probably up there with many of the other
               | least healthy things you could eat, so yeah, ground up
               | wheat with filling to make it taste good is probably
               | fair.
        
               | hombre_fatal wrote:
               | I don't see how that's the case except for a fear of
               | "processing". I plug two slices of commercial whole wheat
               | store bought bread into Cronometer and it has an
               | impressive mineral breakdown and 14% of the day's
               | nutrient needs.
        
               | fatfingerd wrote:
               | Lack of bioavailability analysis and links between
               | processed meat and cancer are fears... of the established
               | scientific community.
        
             | Cerium wrote:
             | Since you don't even have to add the flavors to make corn
             | meal taste good. Look at Fritos - corn + oil + salt.
        
             | cassianoleal wrote:
             | And it's awesome, especially fried!
        
       | gcanyon wrote:
       | Healthcare Triage did a review of the research years ago:
       | https://www.youtube.com/watch?v=Mf82FfX-wuU
       | 
       | tl;dw: artificial sweeteners get a bad rap, multiple studies have
       | found no harm, studies that _did_ find harm were on rats (which
       | often doesn 't translate to humans), and the harms associated
       | with excess sugar consumption are numerous, well-founded, and
       | damning.
        
       | dimitar wrote:
       | This is awful reporting.
       | 
       | Aspartame has been studied for more than 40 years and no
       | regulatory body in any country has found it to be cancerogenic;
       | it is a risky substance for people with a rare desease called
       | Phenylketonuria.
       | 
       | So, the reader will be under the impression that it will cause
       | cancer, which is pretty dubious, all while obesity for which
       | sugary drinks are partially responsible is a very real cancer
       | risk.
        
         | sodathrowaway wrote:
         | Well, is it good or neutral for you? I've always felt like
         | these diet drinks were just marketing to make you think
         | everything was fine, feel free to drink as many as you want.
         | I've worked with a few people that would go through 4-6 Coke
         | Zeros every day. In no world can I imagine that that wouldn't
         | have negative long term effects on a human -- all things in
         | moderation, right?
         | 
         | Personally, I'll drink a Mexican Coke with cane sugar maybe
         | once or twice a year, knowing it's not great for me and
         | treating it as a dessert.
         | 
         | But I do agree, it's not good reporting. Pretty much no info on
         | the actual scientific research, but hopefully WHO will give
         | more in depth data.
        
           | mjburgess wrote:
           | > In no world can I imagine that that wouldn't have negative
           | long term effects on a human -- all things in moderation,
           | right?
           | 
           | Why on earth would you think that?
           | 
           | It's carbonated water with a tiny amount of food dye, sweeter
           | and caffeine. The latter of which, iirc, has generally
           | positive effects.
        
             | crooked-v wrote:
             | Well, the mild acidity is bad for your teeth. Other than
             | that there doesn't seem to be much that stands out as an
             | issue, at least from what we know so far.
        
               | enlyth wrote:
               | Can it be called mild? Diet coke has a pH of 3, which is
               | the same as vinegar
        
             | zelos wrote:
             | There seems to be some suggestion that the sweetness
             | triggers digestive system changes that could be harmful:
             | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772345/
             | 
             | It's very vague though
        
               | pliny wrote:
               | 1. There seems to be some suggestion that X
               | 
               | 2. ???
               | 
               | 3. In no world can I imagine !X
        
             | thesz wrote:
             | [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014832/
             | 
             | [1] shows that artificial sweeteners lead to higher insulin
             | resistance. It is so because they provoke insulin level
             | increase due to their sweet taste.
             | 
             | Caffeine is a tricky one.
             | 
             | If you can drink 6 cups of espresso a day, you have 50%
             | less chance developing dementia. But, how can you drink 6
             | cups of coffee per day if you do not have good health? It
             | can be that the "small positive effects of caffeine" are
             | due to caffeine consumers have a little better health
             | overall and these with worse health have to consume less
             | caffeine.
             | 
             | For an anecdote, I once went completely off caffeine for a
             | month and haven't noticed a thing after first three days,
             | when I was unusually sleepy. Even training results followed
             | the same progression.
        
         | cm2012 wrote:
         | Aspartame is one of the must trustable things we eat. Very few
         | foods have been studied as much as it has. Both quality and
         | quantity of studies.
         | 
         | This is part of how the medical regulation leaders in every
         | country are the most insanely cautious, neurotic people on
         | earth. They all recommend not to eat steaks rare. Everything is
         | a carcinogen. When they have such a low tolerance for danger,
         | it just means everyone learns not to listen to their advice.
        
         | jeron wrote:
         | effectively this is pick your poison: aspartame or sugar
        
           | PreachSoup wrote:
           | Sucralose is another a widely used option. Cokecola uses
           | aspartame, pepsicola uses sucralose. You can also easily buy
           | it off the shelf
        
             | ivanhoe wrote:
             | Sucralose however seems to be stimulating some insulin
             | secretion even though it has no real caloric value.
             | 
             | https://pubmed.ncbi.nlm.nih.gov/19352508/
        
           | 131012 wrote:
           | Well no. May I suggest water?
        
             | carimura wrote:
             | just don't drink TOO much [1]
             | 
             | [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770067/
        
             | seanthemon wrote:
             | You may, thank you
        
             | jandrese wrote:
             | I've found water to be a rather poor sweetener.
        
           | tehnub wrote:
           | I choose Stevia
        
         | TheRealPomax wrote:
         | But what does California's proposition 65 say about it?
        
           | pinkmuffinere wrote:
           | I know this is a joke, but if anyone's curious: Prop65 says
           | you have to tell people if your product contains chemicals
           | from a list of carcinogenic substances. The list is kept up-
           | to-date by California. Prop65 has no punishment for over-
           | reporting though - you can slap on a warning "just for fun"
           | if you want.
           | 
           | Unless California has aspartame on its list, prop65 says
           | nothing about this.
        
             | TheRealPomax wrote:
             | No aspartame, but aspirin's on there.
             | https://oehha.ca.gov/proposition-65/proposition-65-list
        
             | api wrote:
             | Saw a California shirt once that was a prop65 warning:
             | "This shirt has been determined by the state of
             | California..."
        
         | HarfShnarfGobb wrote:
         | > So, the reader will be under the impression that it will
         | cause cancer, which is pretty dubious, all while obesity for
         | which sugary drinks are partially responsible is a very real
         | cancer risk.
         | 
         | Saying it's "partially responsible" in essence is ridiculous,
         | though, when it's also a critical nutrient we eat in virtually
         | every food. Aspartame is not. It's the sheer volume of sugar
         | ingested that's the issue.
        
           | garbagecoder wrote:
           | High fructose corn syrup is not a critical nutrient.
        
         | marcosdumay wrote:
         | AFAIK, most lists of "possible carcinogenic" are just lists of
         | things people want to cause cancer but the evidence disagrees.
         | 
         | There's something to say about lists where people put
         | substances we don't know a lot, to call attention for studying
         | more. But I haven't actually seen one of those, it's always
         | lists of substances people study a lot, and publication bias
         | set them marginally into statistical relevancy.
        
           | autoexec wrote:
           | I doubt very many people want _any_ substance to cause
           | cancer. People want the things they eat to be healthy and
           | wholesome but they 've learned that they can't trust the
           | people making our food or our regulatory agencies to protect
           | them. That's caused people to be cautious and distrustful
           | even when there is little cause for it.
        
         | gjsman-1000 wrote:
         | Why is it awful reporting? The WHO's cancer division (IARC -
         | International Agency for Research on Cancer) is labeling it as
         | being, quite literally, a "possible carcinogen." That's the
         | _actual name of the category_. It's either "Not classified,"
         | "Possible Carcinogen," "Probable Carcinogen," or "Carcinogen."
         | 
         | Don't like it? Bring it up with the WHO.
        
           | mrguyorama wrote:
           | Isn't this the same list that says Cellphones are a possible
           | carcinogen despite mountains of evidence that they cause no
           | cancer and also zero known mechanism of action?
        
           | rowanG077 wrote:
           | That list doesn't even contain "Not a carcinogen". So
           | basically I don't take it seriously at all.
        
           | cwillu wrote:
           | https://www.reuters.com/business/healthcare-
           | pharmaceuticals/...                   LONDON, June 29
           | (Reuters) - One of the world's most          common
           | artificial sweeteners is set to be declared a
           | possible carcinogen next month by a leading global health
           | body, according to two sources with knowledge of the
           | process, pitting it against the food industry and
           | regulators.
           | 
           | [...13 paragraphs later...]                   The IARC's
           | decisions have also faced criticism for          sparking
           | needless alarm over hard to avoid substances or
           | situations. It has four different levels of
           | classification - carcinogenic, probably carcinogenic,
           | possibly carcinogenic and not classifiable. The levels
           | are based on the strength of the evidence, rather than
           | how dangerous a substance is.
           | 
           | Using a term with a technical definition that isn't remotely
           | close to the plain english meaning of the composing words, in
           | a headline--and not explaining the gag in the first paragraph
           | --is terrible reporting
        
           | sampo wrote:
           | > The WHO's cancer division (IARC - International Agency for
           | Research on Cancer)
           | 
           | IARC is only nominally under WHO. It is a weird French agency
           | founded by some French activists and politicians in the
           | 1960's.
           | 
           | They use a 5 class classification                   Group 1:
           | The agent is carcinogenic to humans.         Group 2A: The
           | agent is probably carcinogenic to humans.         Group 2B:
           | The agent is possibly carcinogenic to humans.         Group
           | 3: The agent is not classifiable as to its carcinogenicity to
           | humans.         Group 4: The agent is probably not
           | carcinogenic to humans.
           | 
           | But out of the 1042 chemicals and things they have
           | classified, none are in Group 4. (Historically, there once
           | was one single chemical in Group 4, but they have
           | reclassified it.)
           | 
           | For IARC, everything is either at least possibly
           | carcinogenic, or there is insufficient evidence (Group 3) to
           | yet declare it carcinogenic.
           | 
           | Also:
           | 
           |  _" In 2019 IARC was accused of cooperation with "toxic tort
           | law firms" who make profit of suing companies for
           | compensation for alleged health issues based on IARC
           | classification. IARC was accused from hiding conflicts of
           | interest impacting a few invited experts, especially those
           | related to large-scale cash flows from US law firms."_
           | 
           | https://en.wikipedia.org/wiki/International_Agency_for_Resea.
           | ..
           | 
           | Many countries have perfectly capable chemicals agencies and
           | food safety agencies, who are much more reliable than the
           | IARC.
        
         | ravenstine wrote:
         | Purely anecdotal, but I used to drink _insane_ amounts of
         | aspartame in the form of Crystal Lite. I don 't know what
         | that's made of now, but decades ago it was made with aspartame,
         | and I'd guzzle gallons upon gallons of that stuff because it
         | could be mixed with tap water and was therefore cheaper than
         | buying drinks in cans. Maybe in the long term it will cause my
         | butt to fall off in my 60s, IDK, but if aspartame causes
         | cancer, then it must be incredibly weak given the unglodly
         | amounts I was consuming on a daily basis.
         | 
         | Today, I'd still avoid aspartame, but also sucralose, because
         | it's unnecessary and may even cause insulin to be artificially
         | raised in response to the sweetness. And I also just don't
         | drink nearly as much as I used to now that I'm metabolically
         | healthy.
        
           | asfgidonhio wrote:
           | It's a common fallacy that increasing the dose necessarily
           | increases the effects. There are a whole lot of chemicals
           | where the relationship is more complex. There are drugs where
           | negative effects only occur when the drug is discontinued,
           | where the effect of the drug increases or decreases as it it
           | taken continuously, where the effect rapidly saturates and
           | does not increase with increasing dose, and so forth.
           | 
           | I know enough about pharmacology to know that I know nothing.
        
             | ravenstine wrote:
             | > It's a common fallacy that increasing the dose
             | necessarily increases the effects.
             | 
             | Can you provide an example of a chemical which has effects
             | on the human body that are completely unrelated to the size
             | of the dose? Just because the effects of a carcinogen may
             | be non-linear in relation to the dosage, that doesn't mean
             | that a greater risk of cancer incidents with a greater dose
             | is an unreasonable expectation. Some thing _can_ be assumed
             | unless an exception is identified.
        
         | satysin wrote:
         | Indeed it is awful.
         | 
         | The BBC has a reasonably good article on this subject today
         | 
         | https://www.bbc.com/news/health-66057216
        
         | EA-3167 wrote:
         | I file it under the same category as, "The Daily Mail trying to
         | divide every known substance into ones which cause cancer, and
         | ones which cure it."
        
           | mrguyorama wrote:
           | This venn diagram is just a circle
        
             | EA-3167 wrote:
             | And the label for that diagram is that "I'm not saying it's
             | aliens" guy, but instead of 'aliens' he's saying,
             | "CHEMICALS".
        
       | glonq wrote:
       | A few of the conspiracy nutters that I know firmly beleive that
       | "Big Aspartame" is responsible for suppressing information about
       | its dire negative effects.
       | 
       | But when you consider:
       | 
       | - how many doctors and scientists are personally/professionally
       | motivated to research this
       | 
       | - how many gov't organizations are concerned about this
       | 
       | - how many industry competitors would benefit from discovering
       | this
       | 
       | - how many lawyers would get rich from exploiting this
       | 
       | ...then I somewhat doubt that one group could suppress all of
       | this, globally, for 40+ years. At this point, aspartame is
       | probably one of the most researched food additives out there.
        
         | User23 wrote:
         | > ...then I somewhat doubt that one group could suppress all of
         | this, globally, for 40+ years. At this point, aspartame is
         | probably one of the most researched food additives out there.
         | 
         | Have you ever heard of tobacco? Suppressing information about
         | the harmful effects of a popular consumer product for decades
         | is observably within the capabilities of at least some who
         | might wish to do so.
        
         | kelipso wrote:
         | And yet it took 40+ years for its danger to be widely
         | acknowledged. Forgive me but for thinking there is something
         | suspicious going on... Frankly, the Big Aspartame should be the
         | default explanation and any other explanation be under more
         | scrutiny.
        
           | samtho wrote:
           | Big Aspartame does not exist in a vacuum, however. The sugar
           | industry is arguably bigger, more powerful, and has even more
           | budget to fund motivated research. I don't trust Big
           | Aspartame to prove to is that it is safe, but I put my full
           | faith in Big Sugar to tell us if something is wrong with
           | Aspartame.
        
             | glonq wrote:
             | I'm not sure that I even beleive in "Big Aspartame". The
             | patents have expired, so there are dozens of companies who
             | manufacture it globally. I doubt that they all meet at
             | their global secret cabal hideout to align their plans to
             | extinguish all research.
        
         | samtho wrote:
         | To expand on point number 3, the sugar industry is one of the
         | most notorious at utilizing motivated research to its own
         | benefit. If aspartame had even slightest chance of causing
         | illness or cancer, you could bet on the inevitable, unrelenting
         | smear campaign that Big Sugar would be waging against it.
        
           | vosper wrote:
           | Who are the players in Big Sugar who works exploit this?
           | Can't be the likes of Coca-Cola and PepsiCo, because they'd
           | also be part of Big Aspartame.
        
           | vosper wrote:
           | Who are the players in Big Sugar who would exploit this?
           | Can't be the likes of Coca-Cola and PepsiCo, because they'd
           | also be part of Big Aspartame.
        
             | samtho wrote:
             | You're correct that soft drink providers have no horse in
             | this race as they are mere consumers of sweetening agents,
             | and the their product output depends on customer demand. It
             | would hardly make much difference to them if 90% of
             | consumers started to prefer Diet Coke over Coca-Cola, they
             | would just make more Diet Coke.
             | 
             | The sugar industry's escapades are well known. Most
             | notably, the SRF's (Sugar Research Foundation) war on
             | dietary fats[0][1].
             | 
             | [0]: https://www.npr.org/sections/thetwo-
             | way/2016/09/13/493739074...
             | 
             | [1]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099084/
        
               | throwaway38249 wrote:
               | They need to sell something, if people believe sugar is
               | bad, sweeteners are bad, even disposable plastic bottles
               | are bad, what's left?
               | 
               | Edit to add something more concrete, we already have the
               | "sugar tax" in the UK, to avoid it soft drinks went
               | mostly sugar free or reduced sugar substantially, and
               | replaced it with sweeteners.
               | 
               | And now: https://www.thegrocer.co.uk/artificial-
               | sweeteners-to-face-go...
               | 
               | Simultaneously:
               | https://www.gov.uk/government/news/deposit-return-scheme-
               | for...
        
             | freedomben wrote:
             | Corn farmers are a huge part (because their product makes
             | high fructose corn syrup) and they are highly effective
             | lobbyists.
             | 
             | They are also the ones that pushed ethanol on us and told
             | us it wouldn't hurt our engines (even though it absolutely
             | did. Most engines now are designed with ethanol in mind,
             | but ethanol gas destroyed a lot of otherwise perfectly fine
             | engines before people realized it was a huge lie. By then
             | it was too late anyway)
             | 
             | With the presidential primaries coming up we'll get another
             | big reminder about how disproportionately influential the
             | Iowa corn farmers are.
        
       | GRBLDeveloped wrote:
       | https://en.wikipedia.org/wiki/IARC_group_2B
       | 
       | I read through this list before when I was talking to a
       | conspiracy theorist about 5G. Radio frequencies are on this list.
       | As are caffeic acid (found in coffee, wine, mint), aloe vera and
       | pickled vegetables.
        
         | LegitShady wrote:
         | Caffeic acid may be a carcinogen but I do not think any decent
         | studies have found a connection between drinking coffee and
         | cancer, and in fact some have found the opposite.
        
           | codr7 wrote:
           | A bigger problem is likely caffeine inhibiting uptake of
           | vitamin D and disrupting sleep.
        
       | tekla wrote:
       | > The "radiofrequency electromagnetic fields" associated with
       | using mobile phones are "possibly cancer-causing"
       | 
       | Wow. Easier to list out what doesn't cause cancer
        
         | umeshunni wrote:
         | Did you know that sunlight causes cancer?
        
         | marginalia_nu wrote:
         | The word "possibly" does a lot of heavy lifting in having this
         | make sense.
        
         | beders wrote:
         | Yeah, with billions of cell phone users humankind is
         | practically dead now....
        
       | jeegsy wrote:
       | One would have hoped for a more definitive statement (either way)
       | than 'possible'
        
       | jncfhnb wrote:
       | Do other people feel like aspartame introduces a tangible
       | viscosity into drinks? I feel like it's like drinking slime
        
         | CydeWeys wrote:
         | The opposite. Real sugar makes a drink much more viscous. Fake
         | sugar leaves the mouth feel thin.
        
         | vvilliamperez wrote:
         | I think what you experiencing is an overproduction of saliva to
         | dissolve what your body thinks is sugar.
        
       | mrabcx wrote:
       | Perhaps this will finally increase the popularity of Stevia.
        
         | RamblingCTO wrote:
         | Just live healthy. I hate the addition of stevia and other
         | sweeteners to everything. Please give me cane sugar. I'm a
         | grown up, I can handle my intake, thanks. (Especially anything
         | in the direction of soylent, green shakes etc. No need for
         | stevia.)
        
       | sgbeal wrote:
       | The weird thing about this is that i stopped drinking Diet Coke,
       | specifically because of aspartame, after reading this same thing
       | in 1996 or perhaps early 97. WHO's decision to wait nearly 30
       | years before backing that just makes them look impotent.
        
         | lotsofpulp wrote:
         | FYI, according to the linked article, the WHO is not claiming
         | what you think it is claiming.
         | 
         | >It is preparing to label the sweetener as "possibly
         | carcinogenic to humans", Reuters reported on Thursday. That
         | would mean there is some evidence linking aspartame to cancer,
         | but that it is limited. The IARC has two more serious
         | categories, "probably carcinogenic to humans" and "carcinogenic
         | to humans".
         | 
         | >It previously put working overnight and consuming red meat
         | into its probably cancer-causing class, and listed using mobile
         | phones as possibly cancer-causing.
         | 
         | >The IARC safety review was conducted to assess whether or not
         | aspartame is a potential hazard, based on all the published
         | evidence, a person familiar with the matter told the Guardian.
         | However, it does not take into account how much of a product a
         | person can safely consume.
         | 
         | Some pretty weak claims. Especially weak considering the risk
         | of aspartame (which are not confirmed, and not at amounts
         | regularly consumer) relative to the risk sugar it replaces
         | (which are guaranteed at amounts regularly consumed - see type
         | 2 diabetes).
        
         | nerdponx wrote:
         | As a kid in the 90s I remember seeing health warnings on things
         | like artificially-sweetened chewing gum. I have a very specific
         | memory of asking my dad about it at the local deli.
        
         | lkuty wrote:
         | We got to stay actively informed to be eating good stuff way
         | sooner than the official position of the government about
         | various foods. There are so much bad stuff in the typical
         | supermarket. One way is reading the "right" books.
        
           | gnulinux wrote:
           | How can a layman determine the right book? Anti-vax kooks
           | also think they're reading the right sources.
        
             | rcme wrote:
             | I disagree with the GP that staying informed about
             | nutrition can be done with books. There is very little
             | generally accepted science when it comes to nutrition. I
             | try to use the "test of time" approach. If we haven't
             | figured out that something was bad after at least 500
             | years, then it probably isn't _that_ bad. If we 've been
             | eating a food for less than 500 years, then it should be
             | considered suspect.
        
               | chimeracoder wrote:
               | > If we haven't figured out that something was bad after
               | at least 500 years, then it probably isn't that bad. If
               | we've been eating a food for less than 500 years, then it
               | should be considered suspect.
               | 
               | While I agree with the spirit of this, I'll point out
               | that tobacco was brought to Europe over 500 years ago,
               | and only recently discovered to be one of the most
               | unhealthy products available. Not to mention that it was
               | widely used in the Americas for long before that.
               | 
               | In fact, 450 years after Columbian contact, the medical
               | consensus was that tobacco was _good_ for health.
        
               | jjoonathan wrote:
               | Tobacco is an all-natural plant product backed by
               | longstanding tradition! How could it possibly be bad for
               | your health?
               | 
               | Ugh, if we hadn't banned them from advertising they would
               | absolutely be using this angle and it would absolutely be
               | working.
        
               | saalweachter wrote:
               | Isn't this essentially part of the not-quite-marketing
               | for marijuana? It's not highly processed like tobacco
               | cigarettes, it's just natural?
        
               | taeric wrote:
               | Well, it is more than a little insane how much worse
               | cigarettes were from the things that were added to it.
               | Even more crazy, to me, to consider how nicotine is by
               | and large not what made them bad. Such that I'm honestly
               | not clear on why there aren't more uses of that.
        
               | stcroixx wrote:
               | I'm with you. Sad there's so little knowledge or trust in
               | that knowledge that we have to just observe over a long
               | time scale like this.
        
             | adriand wrote:
             | You don't need to read a book. I think you can get away
             | with three steps:
             | 
             | 1) This maxim from Michael Pollan: "Eat food [1]. Mostly
             | plants. Not too much." (I personally follow an adjusted
             | version of this: "Eat food. Only plants. Not too much.")
             | 
             | 2) Review daily nutrient requirements to ensure your diet
             | is providing you with adequate macro (protein, carbs, fat)
             | and micronutrients (vitamins, minerals).
             | 
             | 3) A few months after adopting your new diet, get a high
             | quality blood test that covers markers like iron, B12,
             | etc., and make any required adjustments to what you're
             | eating.
             | 
             | 1: "Real food doesn't have a long ingredient list, isn't
             | advertised on TV, and it doesn't contain stuff like
             | maltodextrin or sodium tripolyphosphate. Real food is
             | things that your great-grandmother (or someone's great-
             | grandmother) would recognize."
             | https://michaelpollan.com/reviews/how-to-eat/
        
               | count wrote:
               | "You don't need to read a book". Immediately cites a
               | book.
               | 
               | I don't disagree with your assertion on steps, to be
               | clear, just that you aren't answering the actual
               | question. How can you trust Pollan (I'm not saying you
               | can't, just...that's the core question the OP was
               | asking).
        
               | skummetmaelk wrote:
               | And if you eat too many of the wrong plants you get
               | kidney stones etc. etc. Emphasizing variety is very
               | important.
               | 
               | It's almost like a second job to keep up with what you
               | _should_ do. Reviewing daily nutrients is way too much
               | effort for most folks.
        
             | 2devnull wrote:
             | Does it confirm your priors? Then it's right.
        
             | kodyo wrote:
             | It's impossible for a layman to know because most people in
             | accredited positions of authority lie without cessation.
             | 
             | Identify people you trust on a subject, filter their claims
             | through your own ideas about what is reasonable, and hope
             | for the best.
             | 
             | You might still get it wrong. Such is life.
        
               | failbuffer wrote:
               | That's not enough: you should also read the critics and
               | opponents of what you think is true. That is, if you're
               | truly trying to figure out reality and not just seeking
               | psychological security.
               | 
               | Remember, the test of a true intellectual is that they
               | can convincingly defend a position they find abhorrent.
        
               | skrtskrt wrote:
               | I've recently noticed on TikTok a big trend of food
               | scientists, and chemists that basically just aggressively
               | "debunk" anyone saying any sort of preservative or
               | processed food ingredient is bad for you, and they always
               | fall back on "proven safe for human consumption" which is
               | just like circular reasoning that the FDA is perfect,
               | righteous, and good.
               | 
               | There is of course a lot of kooky beliefs out there about
               | food. But it seems like there is a very intentional
               | social media campaign to associate ANY claim that the
               | stuff in our food is not in our best interest with the
               | kooks that believe the only safe thing to eat is raw goat
               | balls or whatever.
               | 
               | For books anyway, I found The Hundred-Year Lie to be
               | incredibly in depth, but there's a lot of chemistry so
               | it's verrry dense.
        
               | iopq wrote:
               | Or you just read a scientific paper. It's called a review
               | and it goes over several studies and uses statistics to
               | determine probability of claims. For example,
               | 
               | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227014/
               | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776645/
        
         | ranger_danger wrote:
         | Where's the proof that drinking Diet Coke causes literally any
         | health issue that is a direct relation to the aspartame itself
         | specifically? Because I don't think that has ever existed
         | because it's not actually harmful in this way... meanwhile your
         | post reads like FUD.
        
           | brewdad wrote:
           | Where's your proof that gravity exists and that we fully
           | understand all of its effects?
           | 
           | Science doesn't work that way. Meanwhile aspartame has been
           | _linked to_ many health problems.
        
           | kagakuninja wrote:
           | You can start here: https://www.mayoclinic.org/healthy-
           | lifestyle/nutrition-and-h...
           | 
           | Diet sodas with aspartame contain a warning for this reason.
           | Now of course, most of us do not have this condition.
           | 
           | But how do we know if it is safe? I decided 20+ years ago
           | that artificial sweeteners were a crutch with no nutritional
           | value and unknown risks, so I stopped consuming them.
        
             | lotsofpulp wrote:
             | Considering that sugar and excess consumption of
             | carbohydrates is the number 1 health problem around the
             | world, is it possible that the risks of low calorie
             | sweeteners are not sufficient to outweigh the benefits of
             | low calorie sweeteners?
        
               | dham wrote:
               | I was just explaining this to my wife while we've been on
               | keto. Yes, artificial sweeteners are bad, let's try to
               | avoid them if possible, but if consuming some aspartame
               | in jello helps us stay on keto and lose belly fat, then
               | the benefits outweigh the risk.
        
               | monkpit wrote:
               | Artificial sweeteners may[0] adversely affect the gut
               | microbiome.
               | 
               | However, other studies suggest that artificial sweeteners
               | break down so quickly that they never reach the gut.
               | 
               | It needs more research, but personally I choose to favor
               | sugar over sweeteners, and just limit my consumption of
               | sugar.
               | 
               | [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156656/
        
         | arbitrage wrote:
         | Personally I'm taking the WHO announcement as an implicit
         | signal that they are no longer so tightly controlled/held
         | captive by corporate interests as they have been for the past
         | ... three, four decades?
         | 
         | Better late than never, I guess.
        
       | SirMaster wrote:
       | Existing... is a possible cancer risk.
        
       | tptacek wrote:
       | The challenge you have here is that aspartame isn't just one of
       | most widely studied substances in the food chain, but that it's
       | also one of the most widely and vigorously consumed. People drink
       | a _lot_ of diet soda; a lot of people drink it to the exclusion
       | of all other liquids. So it 's going to be tricky to get the
       | epidemiology to match up with the claim here: if aspartame is
       | meaningfully carcinogenic (meaning: more than by the trace
       | amounts all sorts of other things in the food supply are, from
       | small quantities of mold due to spoilage to acrylamide forming in
       | almost anything we cook), we'd expect to see a pretty obvious
       | effect in case rates.
       | 
       | The article mentions a French study showing a "slight" increase,
       | over 100,000 pts, in an observational study that used self-
       | reporting to control for other risk factors. I can't find it; has
       | anyone else?
        
         | TheBlight wrote:
         | Tell me you're a Diet Coke fiend without telling me you're a
         | Diet Coke fiend.
        
           | tptacek wrote:
           | I don't consume caffeine, but Dave Arnold of the
           | (unimpeachable) Cooking Issues podcast has a whole spiel
           | about how Diet Coke drinkers use it as a primary source of
           | hydration.
        
       | femboy wrote:
       | I wish there was a switch in the mass production of products to
       | contain neither sugar or sweeteners.
       | 
       | But it feels like that is never going to happen.
        
         | SirMaster wrote:
         | There are plenty of products that have an unsweetened version,
         | at least in my experience.
        
         | time0ut wrote:
         | No chance there would be a switch. Consumer tastes and eduction
         | aren't going to change.
         | 
         | Short of that, I wish there was clearer and more consistent
         | labeling. I avoid sugar and sweeteners. Its annoying to be in
         | the mood for a flavored drink, see something that claims to be
         | zero sugar/all natural/etc, grab it in a hurry, then discover
         | on the first sip its got erythritol in it. I read the label,
         | but sometimes I miss it. My preferred options are unsweetened
         | iced tea, coffee, or flavored water. Those are reliable, but
         | can get boring.
         | 
         | Food is generally easier. I just avoid anything that has (or
         | should have) a lot of carbs as a rule when looking for
         | convenient pre-packaged food. No point in sweetening a can of
         | sardines...
        
         | SoftTalker wrote:
         | You can do it yourself. I used to drink a lot of sweetened
         | soda. I switched to diet, then stopped. Regular sugar-sweetened
         | drinks taste sickeningly sweet to me now, and diet drinks taste
         | like chemicals.
         | 
         | Once you break the habit, your sense of taste recovers and you
         | realize how nasty these drinks are. Most people get started on
         | them as kids when you don't have a nuanced sense of taste and
         | really crave sweet stuff.
        
           | [deleted]
        
           | brewdad wrote:
           | Same. I used to drink multiple Cokes a day. I switched to
           | Diet Coke sometime in my late 20s. In my 30s I cut back to
           | one Diet Coke a day and about 4 years ago in my mid 40s I
           | switched over to carbonated water when I crave something
           | fizzy but still limit myself to one a day most days. Coffee
           | and plain water have replaced the soda I used to drink.
           | 
           | This was all done over time as I realized I needed to change
           | my diet to keep weight off and I wasn't really enjoying my
           | daily soda(s) anyway. With an actual intent, one could drop
           | soda within a few months easily and never miss it.
        
             | nwienert wrote:
             | Until you realize caffeine has long term negative effects
             | on sleep even at low doses. Only the pure water drinkers
             | can claim any moral high ground! (I'm not one of them)
        
         | stronglikedan wrote:
         | Why would there be? Sugar is good. Products with sugar are
         | good. Self control is also good. People can like products with
         | sugar and exercise self control, so there will always be a
         | demand for mass produced products with sugar, and that's a good
         | thing.
        
           | sp332 wrote:
           | Self control doesn't reduce the amount of sugar that's
           | already added to the soda I would like to drink. It just
           | means I don't get to drink it. I have to go find low-sugar
           | sodas. I would like to have more options.
        
           | dham wrote:
           | We have to stop putting sugar in dumb things first, like
           | ketchup and bacon. We have to get a grip.
        
         | kagakuninja wrote:
         | I just started brewing my own tea and coffee, unsweetened.
         | Snack foods are a bit harder, but we are better off eating
         | whole fruits and vegetables anyway.
        
       | marvel_boy wrote:
       | Curiously the share value of COKE has not plunged today. (+0.21%
       | as we speak)
        
         | 2OEH8eoCRo0 wrote:
         | Why would it? If it's a carcinogen for Coke then it's a
         | carcinogen for Pepsi or everyone else.
        
         | [deleted]
        
         | pessimizer wrote:
         | Coke owns most sodas, so if you're switching, you're likely to
         | end up switching to another Coke product.
        
         | blibble wrote:
         | they'll just swap it out for the next artificial sweetener
         | 
         | and that'll be found to be bad in 20 years time, then they
         | repeat again
        
       | cheekibreeki2 wrote:
       | Just returned from Ireland and every 'regular' soda was full of
       | disgusting artificial sweeteners. In the usa these would be
       | labeled diet. And of course sucralose was pretty common and we're
       | now finding scary things about its harm to the human body. Sugar
       | really isn't that bad..
        
         | biomcgary wrote:
         | As a biologist, I can tell you that sugar really is bad. All
         | sorts of nasty effects (e.g., look at the RAGE gene and
         | pathway). Of course, that doesn't mean artificial sweeteners
         | are a good alternative. Limiting added sweeteners of any kind
         | is a good idea, just hard to follow.
        
           | kushan2020 wrote:
           | You are making it sound like alcohol - where the warning is
           | no amount of alcohol is safe.
           | 
           | Sugar is a naturally occurring substance and is totally safe
           | for consumption. However, purified added sugar is bad for you
           | because in nature you cannot find a fruit that contains that
           | many sugars per gram.
        
         | OkayPhysicist wrote:
         | Sugar in the amount put in soda absolutely is terrible for you.
         | The problem definitely is with people drinking too much soda,
         | period, but replacing your average Americans's diet soda
         | consumption with sugar soda consumption works out to an average
         | increase of ~73 calories/person/day. Of course, most of that
         | consumption is being done by the subset of the population
         | currently primarily drinking diet soda, which multiples that
         | number by 2-5 depending on what study you refer to. Which would
         | definitely be an alarming increase in caloric consumption in a
         | significant block of the population.
        
           | bamfly wrote:
           | It's _really weird_ that we 've normalized consuming huge
           | amounts of what's effectively an exceptionally-sweet dessert
           | drink with most non-fancy restaurant or fast-food meals. Shit
           | made a lot more sense when standard serving size was like 7oz
           | and free soda refills weren't a common thing (so: the 1950s
           | or whenever, for the former, and before some time in the
           | '90s, for the latter). 20+oz glasses (and 32oz "medium-size"
           | to-go cups--JFC) and free refills pushed by servers are just
           | nuts. That's _so very much_ sugar.
           | 
           | Imagine consuming a pile of 37 Pixy Stix (sugar equivalent of
           | 24oz of Coca Cola) to accompany a hamburger. WTF. That's
           | plainly nasty as hell, and anyone doing that in public would
           | rightly feel ashamed. And that's not even a large serving of
           | soda, by modern standards.
        
             | lfowles wrote:
             | The cups are usually 3/4 full of ice to start with, heh
        
           | taeric wrote:
           | 73 calories actually sounds misleadingly low? How is that
           | calculated?
           | 
           | I think this is what you are correcting in the rest of the
           | post? In that a single soda is typically double that. And
           | many folks drink more than a single soda. Considerably more.
        
             | OkayPhysicist wrote:
             | The average American consumes 38.87 gallons of soda year.
             | 43% of Coke sales are Diet, I extrapolated that across the
             | market, since Coke has a pretty dominant market share
             | anyway. That's 16.7 gallons of diet soda per American, or
             | 178 cans of soda. Multiply that by 150 calories/can, divide
             | by 365, you get the 73 calories.
             | 
             | As I mentioned before, that's a side effect of averaging
             | across all Americans, a fraction of who don't drink soda,
             | and a (much larger, in both senses of the word) who drink
             | sugared soda. The population that those calories would
             | realistically be distributed over, the diet soda drinkers,
             | is somewhere between 20% and 40% of the population, hence
             | the "multiply by 2-5".
        
               | taeric wrote:
               | Makes sense; but I think it is odd to include folks that
               | aren't relevant in the increase, though. Really, it is
               | just weird to see a number that the only way to see an
               | increase of 78 calories is to swap over into a half of a
               | drink.
               | 
               | Granted, you work with what you have. :D
        
               | OkayPhysicist wrote:
               | Yeah, I suspect it works out closer to the "350 more
               | calories per day in 20% of the population" number, but
               | again, sources were rough.
        
         | mandmandam wrote:
         | Sugar is pretty bad. Glucose spikes cause a huge amount of
         | stress in the body.
         | 
         | But yeah, Ireland's drinks are like that because of a 'sugar
         | tax', and now it's quite hard to find fizzy drinks without
         | gross sweeteners. Even brands that were quite high quality
         | before are kinda rancid now.
        
         | mcdonje wrote:
         | Just because we're finding out many sugar replacements are bad
         | doesn't mean that sugar isn't bad in high doses as with sugary
         | drinks.
        
           | beebeepka wrote:
           | Don't consume high doses of anything. Sugar is fantastic.
        
       | jxidjhdhdhdhfhf wrote:
       | Reminder that bacon is already a known carcinogen for those
       | worrying about artificial sweeteners but happily eating processed
       | meats.
        
         | penneallagricia wrote:
         | With bacon you know what you get, so you can dose it and take
         | your risks. Aspartame has been sold to us as the healthy
         | alternative to sugar. People literally use aspartame as an
         | excuse to chug liters of soda every day.
        
         | LegitShady wrote:
         | It's actually sodium nitrite that's carcinogenic (after being
         | exposed to high heat), and I can find bacon without sodium
         | nitrite here pretty much at every grocery store.
        
           | [deleted]
        
           | remote_phone wrote:
           | If you read carefully, it still contains sodium nitrite
           | except as powdered celery. So the source of the sodium
           | nitrate is "natural" but the dose is still the same.
        
             | LegitShady wrote:
             | Fml so I've been paying more for nitrite free bacon that
             | still has nitrite in it?
             | 
             | It feels like saying something contains no nitrites or
             | preservatives and then including them in the form of
             | cultured celery extract should be fraud/false advertising
             | and a crime.
        
               | tptacek wrote:
               | You extremely have been conned by the "nitrite-free
               | bacon" labeling, yes. This is something that food writers
               | have been complaining about for over a decade.
        
           | malnourish wrote:
           | Adding to what remote_phone said, and repeating another
           | comment of mine, that nitrite free bacon still has the same
           | amount of nitrites (in some cases, more).
           | 
           | https://www.americastestkitchen.com/cooksillustrated/how_tos.
           | ..
        
             | LegitShady wrote:
             | There's one place near me that sells actual nitrate/nitrite
             | free bacon but its super expensive - $10-12 Canadian for
             | 250grams or so. It like double bacon in the store and its
             | an hour drive away.
             | 
             | Sad to learn about the celery nitrite thing. I've been
             | overpaying for it for a while now, apparently. It literally
             | says "contains no preservatives" but has "cultured celery
             | extract" in the ingredients, so its a lie.
        
           | galangalalgol wrote:
           | If it is completely uncured sure, but usually niteite/nitrate
           | free bacon has an asterisk saying something like "beyond what
           | is naturally found in the added celery juice". If you heat
           | those nitrites in the bacon it doesn't the same thing as the
           | synthetic stuff would. Luckily trichinosis is largely a thing
           | of the past, so why heat it? Uncooked bacon tastes awesome.
           | Also, in stews I believe it does reach the dangerous temps?
        
           | tptacek wrote:
           | Sodium nitrate converts to sodium nitrite over the course of
           | a cure; that's why Prague Powder #2 is used for long-term
           | cures.
        
         | Fezzik wrote:
         | My understanding is that bacon itself is not the culprit of the
         | possible (note -- possible) carcinogen. The sodium nitrate that
         | is often used as a preservative is. Nitrate-free bacon is easy
         | to find though.
        
           | malnourish wrote:
           | Nitrate-free (or, "no nitrates added") bacon still contains
           | nitrates. About the same amount as standard bacon, and in
           | some cases, more.
           | 
           | https://www.americastestkitchen.com/cooksillustrated/how_tos.
           | ..
        
             | raspyberr wrote:
             | In the UK, we have nitrate-free bacon available that is
             | actually nitra(i)te free:
             | https://www.betternaked.com/products/better-naked-
             | unsmoked-b...
        
               | malnourish wrote:
               | I'm intrigued. That seems a fair bit different than the
               | uncured bacon I'm familiar with in the US [0], but I
               | would certainly give it a try.
               | 
               | [0]: https://applegate.com/products/natural-thick-cut-
               | bacon
        
               | tptacek wrote:
               | To what everybody else is saying, I'll add that by the US
               | definition, that's not bacon; it's back bacon, which is a
               | loin cut, radically different than American bacon, which
               | I believe you lot call "streaky bacon".
        
               | toolz wrote:
               | I don't see anything on that site that says anything
               | other than nitrates weren't added. Where are you seeing
               | that it's actually nitrate free?
        
               | malnourish wrote:
               | Under "Dietary information" at the bottom of the page, it
               | says "Nitrite-free, Gluten-free, Dairy-free,[sic]"
        
               | toolz wrote:
               | I wouldn't be surprised if that's misleading considering
               | the other article was suggesting nitrite precursors are
               | usually what's in the food later to be turned into
               | nitrite, but I'd love to be wrong.
               | 
               | You could simply measure the levels of nitrite before any
               | exists and the end product might still have just as much.
        
               | maxerickson wrote:
               | The one article is talking about celery juice being
               | stealth nitrates. It's not something that is in the pork
               | itself.
               | 
               | The only candidate would be natural flavors, and I sort
               | of doubt that they would get away with that.
        
             | tracker1 wrote:
             | Better stop eating celery or anything containing it if
             | you're really concerned about nitrates.
        
             | hosteur wrote:
             | I cute and smoke my own bacon. I do not use nitrite. Also
             | in my country organic bacon has zero nitrate in it.
        
         | Lonewolfa wrote:
         | Source please
        
           | jxidjhdhdhdhfhf wrote:
           | https://www.who.int/news-room/questions-and-
           | answers/item/can...
        
         | adrr wrote:
         | Or drinking hot tea. Working graveyard shift. Drinking alcohol.
        
           | 93po wrote:
           | Breathing air in any city.
        
         | tptacek wrote:
         | Why stop with nitrates and nitrites? Acrylamide is a known
         | human carcinogen, and occurs in a huge variety of cooking
         | processes (including baking, frying, and grilling). If you eat
         | potatoes, you're almost certainly putting yourself at more risk
         | than aspartame is: we've got epidemiology and mechanism of
         | action to back up the potato risk.
        
           | likpok wrote:
           | I believe California even helpfully warns you about any
           | location that has acrylamide.
        
       | [deleted]
        
       | thrawa8387336 wrote:
       | Meh, I'd sooner believe it treats depression. Try having a Diet
       | Coke and report on the 24h after ;)
        
       | mhanberg wrote:
       | Literally read halfway down the article before they say that
       | "working overnight" is also in the "probably carcinogenic"
       | category and that the organization is known for publishing
       | confusing results that cause panic.
       | 
       | FFS
        
         | fortenforge wrote:
         | Actually "working overnight" is "probably carcinogenic" which
         | is a higher evidentiary standard than Aspartame which is
         | "possibly carcinogenic".
         | 
         | Basically these WHO cancer guidelines are entirely useless in
         | terms of public health and have probably done as much harm as
         | Prop 65 has in California.
        
       | yomlica8 wrote:
       | And here I just thought it just tasted kind of off and gave me
       | headaches.
        
       | jcutrell wrote:
       | Honestly, what I want to know in a headline like this is "what
       | changed?"
       | 
       | As someone who deals with health anxiety already, I have done my
       | fair share of research on things like this. Aspartame, along with
       | most other artificial sweeteners, have not been proven to be
       | carcinogenic in _many_ studies done over a 40 year period.
       | Additionally, the hazard ratio of any of these sweeteners in
       | comparison to the equivalent consumption of sugar is laughably
       | small.
       | 
       | So, when something like this happens, I really want to know what
       | the trigger was. My fast-brain fills in the gap with "there was a
       | new breakthrough in research." But, this categorization doesn't
       | imply that necessarily. Just that they are doing a review. But
       | why now?
        
         | recursive wrote:
         | Right here, in this very thread, are comments suggesting that
         | there is _no_ credible evidence that aspartame is a carcinogen.
        
       | nicole_express wrote:
       | I hope this questionable categorization doesn't result in
       | aspartame being removed from sodas; I much prefer it to other
       | artificial sweeteners. Can definitely tell when Diet Coke is
       | formulated to include them.
        
       | brink wrote:
       | That stuff gives me migraines. I can't even chew most gum without
       | a headache because it's full of it.
        
         | moogly wrote:
         | Isn't it mostly Xylitol in chewing gum?
        
           | brink wrote:
           | On the list of gums that give me a headache, it's aspartame
           | on the ingredients list. Believe me, I check. :)
        
           | ajhurliman wrote:
           | Xylitol is actually pretty rare as the main sweetener in gum,
           | it's a lot more expensive. If gum mentions that it contains
           | xylitol, check the ingredient list to see if there are other
           | sweeteners listed first.
           | 
           | Xylitol is preferable because of its oral hygiene benefits,
           | but most consumers are choosy enough to make sure their gum
           | is exclusively xylitol.
           | 
           | There are some brands on Amazon that sell 100% xylitol gum if
           | you go out of your way to find it though. Be careful with it
           | around dogs though, xylitol is insanely toxic to them.
        
           | rootusrootus wrote:
           | The ones I'm familiar with mostly use sorbitol. Though it's
           | not uncommon to find aspartame on the 'less than 2% of the
           | following' part of the ingredients list.
        
         | myshpa wrote:
         | Some gum bases are made from non-degradable plastic polymers
         | ... another reason to stay away.
        
       | dghughes wrote:
       | Weird to have Coke in the Reuters headline when it's not just
       | Coke that uses aspartame.
       | 
       | And this is interesting may be related?
       | 
       | >Aspartame is hydrolysed in the body to three chemicals, aspartic
       | acid (40%), phenylalanine (50%) and methanol (10%). Aspartic acid
       | is an amino acid.
       | 
       | >When there is an excess of neurotransmitter, certain neurons are
       | killed by allowing too much calcium into the cells. ...The neural
       | cell damage that is caused by excessive aspartate and glutamate
       | ... they 'excite' or stimulate the neural cells to death.
       | 
       | >Methanol is highly toxic; it is gradually released in the small
       | intestine when the methyl group of the aspartame encounters the
       | enzyme chymotrypsin. It has been pointed out that some fruit
       | juices and alcoholic beverages contain small amounts of methanol.
       | 
       | source: https://www.3dchem.com/aspartame.asp
        
         | OkayPhysicist wrote:
         | Diet Coke is undoubtedly America's biggest source of aspartame.
         | Diet Coke has massive market share.
        
           | carimura wrote:
           | I had a computer science professor who drank so much diet
           | coke that she had a wall of empty cans stacked up from floor
           | to ceiling in her office. Even then, 20 years ago now, I was
           | so grossed out with that level of artificial intake I wanted
           | to grab her shoulders and shake her. But that wouldn't have
           | helped my grade.
        
             | jaclaz wrote:
             | Not much diet coke, but (JFYI) ...
             | 
             | https://uranus.chrysocome.net/coke.htm
        
             | lotsofpulp wrote:
             | What is "artificial intake"? Would it have been preferable
             | to "real" intake of sugar from regular Coke?
        
             | vore wrote:
             | Why? Why does it matter to you?
        
           | quechimba wrote:
           | Regular coke is probably my biggest source of aspartame now
           | that they changed the recipe to contain 30% less sugar
           | compensated by aspartame and acesulfame-k. I bought a Sprite
           | a while ago and it tasted different so I checked and it
           | doesn't even contain any sugar even though the bottle looks
           | just like before and says "100% saborizantes naturales"
           | (although the sweeteners are artificial). Here's the product
           | page, https://www.coca-cola.com.pe/marcas/sprite
        
       | powera wrote:
       | Everything _might_ cause cancer.
       | 
       | https://astralcodexten.substack.com/p/webmd-and-the-tragedy-...
       | 
       | The current system (especially CA Prop 65) makes it impossible
       | for these pronouncements to carry any meaning whatsoever.
        
       | [deleted]
        
       | throwaway1777 wrote:
       | Ok I'll be that guy. The study says there's no risk unless you
       | drink equivalent of 70 cokes per day. So I think I'm ok. Barely.
        
         | kagakuninja wrote:
         | I've been hearing that type of argument since the 70s, after
         | they banned saccharine.
         | 
         | Let's suppose a chemical causes slow damage to the body, maybe
         | greatly increasing your risk of cancer or alzheimers if you
         | drink a can of diet soda per day. How could we possibly know if
         | it is safe?
         | 
         | We often test chemicals on rats, but the problem is that they
         | only live a few years. No one wants to wait 20+ years to see
         | the results of an expensive study on longer lived mammals
         | anyway.
         | 
         | The solution is we feed the rats excessive amounts of the
         | chemical and see if it causes problems. This isn't a great way
         | to do it, but what other option would you suggest?
        
           | throwaway1777 wrote:
           | I would simply suggest we stop making any strong claims until
           | we do know.
        
         | jjulius wrote:
         | You're not wrong, but the full quote from the article is:
         | 
         | >" _Back in 1981_ they established an acceptable daily intake
         | of aspartame, of 40 milligrams per kilogram of body weight per
         | day. To consume over that limit would require a very large
         | daily consumption of Diet Coke or similar drinks. On 14 July,
         | Jecfa may change that risk assessment, or they may not."
         | 
         | Emphasis mine. I'd be curious to see if this understanding has
         | shifted in the past 42 years.
        
           | benatkin wrote:
           | That doesn't mean it's good for you. I agree with the
           | labeling of it as a neurotoxin, whether or not the rubber
           | meets the pavement at a psychological level. There are better
           | ways of calming for the vast majority of people than
           | satisfying a sweet tooth so often. For one thing it can
           | reduce the overall satisfaction of eating sweet things,
           | through the law of diminishing returns.
        
       | halfjoking wrote:
       | How do they decide these things at the WHO? I imagine it's
       | something like this...
       | 
       | "Sir, people are noticing cancers are skyrocketing among young
       | people after the Covid vaccine. And we can't get Twitter to
       | censor posts like this anymore:"
       | 
       | https://twitter.com/EthicalSkeptic/status/167170602867987661...
       | 
       | Ok what scapegoats do we have for this cancer trend?
       | 
       | We usually tell media to talk about air pollution from climate
       | change, increased stress in modern society or forever chemicals.
       | 
       | No, no , no... those are too new of concepts. People aren't
       | buying it. We need something more timeless, that's been common
       | knowledge for decades.
       | 
       | What about aspartame?
       | 
       | Perfect. I want that report done and published in major media
       | outlets by the end of the week.
       | 
       | Yes sir
        
       | tahoeskibum wrote:
       | Coffee is a known carcinogen (due to formation of acrylamides in
       | roasting). Ripe fruits emit small amounts ethylene that is
       | carcinogenic.
        
       | beebeepka wrote:
       | The whole war on sugar is baffling to me. After I had my first
       | glass of soda in a decade, my impression is that artificial
       | sweeteners are garbage. Poisonous, too. But this has been known
       | for decades, hasn't it. It's cheap, though.
       | 
       | As for me, I am off to the toilet for my drink. It has served me
       | well so far even though it has no taste or electrolytes
        
       | neonsunset wrote:
       | When I accidentally ingest food or drinks containing aspartame,
       | it takes me out for at least 24h with a hellish migraine.
        
         | kyriakos wrote:
         | I suffer from migraines. Usually related to exposure to sun and
         | sleep patterns, I found out that drinking diet coke during a
         | day that I already experienced one of my other triggers, gives
         | me a migraine almost immediately. Any other day it has no
         | effect.
        
         | h2odragon wrote:
         | being a statistical outlier means you don't count. Good luck
         | explaining that to your doctors.
        
           | neonsunset wrote:
           | Statistical outlier? Aspartame is known to be linked to
           | migraine triggering:
           | 
           | - https://pubmed.ncbi.nlm.nih.gov/2708042/
           | 
           | - https://pubmed.ncbi.nlm.nih.gov/18627677/
           | 
           | - https://pubmed.ncbi.nlm.nih.gov/28198207/
        
       | LarsAlereon wrote:
       | To clarify, this doesn't mean aspartame in food is harmful, it
       | means that in certain circumstances it's possible for the
       | chemical to cause cancer. For example, workers exposed to
       | extremely high levels during manufacturing, or breakdown products
       | formed during improper storage.
        
         | arbitrage wrote:
         | So aspartame in food isn't harmful, aspartame used in the
         | production of food is harmful.
         | 
         | Makes me feel so much better.
        
           | netbioserror wrote:
           | Water in the stomach isn't harmful, but water in the lungs
           | absolutely is.
           | 
           | If the human digestive system can trivially break down the
           | amounts of aspartame found in a diet coke, it's fairly
           | pointless for just about anyone to entertain the scenario of
           | inhaling a bucket of pure aspartame crystals.
        
           | SketchySeaBeast wrote:
           | As is often noted, being exposed to too much or improperly
           | stored (heated, cooled, contaminated) water can also be
           | hazardous to your health and that shit's in everything.
        
             | [deleted]
        
           | kergonath wrote:
           | Silica can cause cancer, in the form of asbestos fibres or
           | silica dust. Yet, it's safe to drink from a glass, have
           | windows at home, and walk on sand. A lot of factors matter
           | besides chemical composition.
        
             | fluidcruft wrote:
             | Are you suggesting that aspartame in food has a different
             | physical form that prevents it from entering the body?
        
               | graypegg wrote:
               | It's the dose that makes the poison maybe?
        
               | kergonath wrote:
               | For example. I cannot provide any insight because I don't
               | with in that field, but it would not be necessarily
               | surprising that e.g. inhaled powders could have different
               | effects than ingested compounds diluted in something
               | else. Quantity would matter a lot as well.
        
               | dogma1138 wrote:
               | It's not only if it enters the body but also how, for
               | example inhaling aspartame can be very different to
               | ingesting it.
        
               | xeromal wrote:
               | That's not the only option there. It also could be the
               | amount of exposure.
        
           | [deleted]
        
           | HelixEndeavor wrote:
           | Water isn't dangerous but if you were dropped into the middle
           | of the ocean you would probably drown. Does that mean you
           | must swear off water because it's proven to be dangerous
           | since people drown in it?
        
           | cogman10 wrote:
           | It should.
           | 
           | There are plenty of chemicals that you regularly consume
           | which, in high dosages, are fatal but are required at low
           | dosages.
           | 
           | Too much calcium will causes osteopetrosis (too little does
           | as well).
           | 
           | Too much vitamin K causes liver damage
           | 
           | Too much vitamin B1 causes hypertension
           | 
           | Plenty of stuff is dangerous at high levels and safe at low
           | levels. Our kidneys and liver exist to filter and eliminate
           | excess.
        
             | j45 wrote:
             | Too little or too much of many foods will be bad
             | 
             | Where Aspartame is unhealthy in soda could use more
             | detailed light shed on it.
             | 
             | There may be some issue with how it's used for food and
             | soda in second and third world countries compared to First
             | world.
        
         | penneallagricia wrote:
         | What about the mass of people who in order to drink liters of
         | soda every day ingest large amounts of aspartame? Is it about
         | "circumstances" or concentration?
        
           | j45 wrote:
           | Is litres of soda the battery for Aspartame to be bed for
           | someone?
           | 
           | What about a few cans a week?
        
       | nightski wrote:
       | Thats interesting. All the recent scientific evidence I have been
       | seeing has been saying that Aspartame really isn't bad. This
       | seems suspect. It's so hard to trust science today since it has
       | become so intertwined with politics and corporate agendas.
        
         | hulitu wrote:
         | AFAIK it can cause diarrhea.
        
           | vore wrote:
           | Aspartame is not a sugar alcohol like the other artificial
           | sweeteners that do cause diarrhea due to incomplete
           | digestion.
        
         | carimura wrote:
         | agreed, it's really hard with lobbyists, captured agencies,
         | flawed studies, social media noise, political narratives, etc
         | etc etc. We try our best to just go back to first principles:
         | as close to the food source as possible, as few added
         | ingredients as possible, organic, etc.
        
           | tptacek wrote:
           | Ahh, the naturalist fallacy. But the natural substitutes for
           | artificial sweeteners are markedly worse for you, and more
           | primitive, less industrial cooking and food preparation
           | techniques often can be as well.
        
       | RhodesianHunter wrote:
       | It's always surprising to me how quick we are to go from
       | discovering a chemical to mass-producing it. We're only just
       | figuring out all of the negative externalities of things like
       | PFAS, and they're in absolutely everything (packaging, clothes,
       | pizza box linings, food cans, cookware...)
        
         | aio2 wrote:
         | Yes, "We've" figured out the dangers of PFAS just now, but when
         | companies started producing them back over 50 years ago,
         | company 3M knew it (to say the least) wasn't good.
         | 
         | I'm pretty sure the scientists who dealt with these chemicals
         | even warned against using it, but some higher ups still let it
         | pass
        
         | flashback2199 wrote:
         | Leaded gasoline will really blow your mind, at least it did for
         | me
         | 
         | Edit: Figuratively not literally, haha!
        
           | kzrdude wrote:
           | It was known to be harmful back in 1920s when it was
           | introduced
        
             | justinator wrote:
             | But it solved a problem that got in the way of selling you
             | things!
             | 
             | It's also still used in most every prop engine that flies
             | over my house everyday at a normal schedule, so we still
             | haven't solved the problem of leaded gas. We never will (in
             | my lifetime).
        
               | freedomben wrote:
               | > _It 's also still used in most every prop engine that
               | flies over my house everyday at a normal schedule, so we
               | still haven't solved the problem of leaded gas. We never
               | will (in my lifetime)._
               | 
               | Do you know why? I was under the impression that avgas
               | (aka leaded gas for airplanes) was being forced out
               | (albeit slowly) by EPA
        
           | mcast wrote:
           | Vertasium has a great video on the invention of leaded
           | gasoline: https://www.youtube.com/watch?v=IV3dnLzthDA
        
           | wcedmisten wrote:
           | Interestingly, the inventor of leaded gasoline also invented
           | freon.
           | 
           | https://en.m.wikipedia.org/wiki/Thomas_Midgley_Jr.
        
             | nielsbot wrote:
             | Smithsonian Magazine has an article about that angle
             | 
             | "One Man Invented Two of the Deadliest Substances of the
             | 20th Century" https://www.smithsonianmag.com/smart-
             | news/one-man-two-deadly...
        
         | justinator wrote:
         | 3M knew about the negative "externalities" of PFAS 50 years
         | ago, they just decide YOU didn't nee to know.
         | 
         | https://theintercept.com/2018/07/31/3m-pfas-minnesota-pfoa-p...
         | 
         | It's the same with oil companies having studies on climate
         | change privately, while discounting climate scientists
         | publicly.
         | 
         | Profits over People is the way of Capitalism!
        
           | no_butterscotch wrote:
           | I'm always surprised by this when it's "50 years ago".
           | 
           | Certainly the scientists and analysts at 3M who collected and
           | analyzed the data would have thereafter known of it's
           | extremely harmful effects.
           | 
           | And I don't mean to open this up to "heh yea well they made
           | bank!" I don't think they did relatively speaking.
           | 
           | My main question, is that certainly those scientists would
           | have been advising their friends and families to stay away
           | from X, Y, and Z products because they contain PFAS?
        
             | ethanbond wrote:
             | It's pretty easy to accidentally convince yourself of
             | things when you get a big payday by doing so.
             | 
             | This is why analyzing clinical trial data is so obscenely
             | hard. There are bad actors, there are liars, and there are
             | scientists who are really, really hoping to achieve a
             | breakthrough. All of them are liable to end up putting
             | forth bad information.
        
               | justinator wrote:
               | _> It 's pretty easy to accidentally convince yourself of
               | things when you get a big payday by doing so._
               | 
               | Is it easy to turn a blind eye, when factory workers in
               | your own company were dying, or is what we're describing
               | called at best criminal, and at worst psychotic?
               | 
               | They were literally just dumping these chemicals down the
               | river. They were fined a small fraction of their profits
               | (of billions) and told pretty please to not do it again.
               | This is obvious corruption on so many levels.
        
               | ethanbond wrote:
               | This happened at 3M? What are you referring to?
        
       | mvdtnz wrote:
       | Every now and then I get car parts delivered from USA and without
       | fail they come with a label telling me they cause cancer. I can't
       | take this kind of labeling seriously when it comes from an
       | American source.
        
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