[HN Gopher] Polio is on the brink of eradication ___________________________________________________________________ Polio is on the brink of eradication Author : sohkamyung Score : 292 points Date : 2023-11-23 13:00 UTC (10 hours ago) (HTM) web link (www.nature.com) (TXT) w3m dump (www.nature.com) | hilbert42 wrote: | As someone who lived through the polio epidemic during my | childhood and having seen kids die of the disease or end up in | iron lungs or having to wear calipers for life, I can only say | hallelujah I hope this announcement about its likely eradication | ends up being true. | orra wrote: | Indeed, it'd be wonderful to see polio eradicated. Eradication | has been a decades long program; they originally aimed to do it | by the year 2000, then ?, then 2018. | | Even if the last stage of eradication is stubbornly slow, we | have obviously been quite successful at limiting the number of | cases. | alfredpawney wrote: | Honestly never thought i'd see the day. | smegger001 wrote: | Well it didn't help when the CIA got caught posing as health | workers giving out polio vaccination in Pakistan. | LordShredda wrote: | https://www.theguardian.com/world/2011/jul/11/cia-fake- | vacci... | | The taliban started attacking polio vaccine workers and the | UN suspended operations. Polio exists in Pakistan, | Afghanistan, and Nigeria | codezero wrote: | The scheme was for hepatitis vaccinations. The article | linked below just mentions that only health workers giving | polio vaccines had previously been able to access the | compound. | gumby wrote: | FDR caught polio _in his 20s_ and was wheelchair bound after | that. | | Mitch McConnell had a mild case of polio as a child and once | you know that you can see the resulting trivial impairment in | his gait and facial expressions. However his utterly evil | attitude and actions have nothing to do with polio. | Modified3019 wrote: | I wasn't familiar with the term calipers outside of the | measuring tool. For anyone else wondering, it refers to the leg | braces used by those who have polio induced nerve damage and | subsequent muscle weakness (poliomyelitis). | Mistletoe wrote: | It's amazing what vaccines can do when people take them and they | aren't politically weaponized by AI and social media algorithms. | | Sorry if I'm bitter, I just had a nurse tell me yesterday to not | take the flu vaccine because she said it doesn't prevent flu and | why would I "put that junk in my body." | dotnet00 wrote: | The polio vaccine is also clearly more effective at limiting | the disease than the flu or covid vaccines (granted that this | is in part just the nature of the virus). | philjohn wrote: | Indeed - from my understanding, they have to "guess"timate | which strains of Flu will be prevalent in a given year, if | they get it right, fantastic - if they get it wrong, lower | effectiveness. Of course, it's not really a guess so much as | an educated assessment. | | Having said that, as an asthmatic I've had the Flu vaccine | every year for the last 20 or so years, and knock on wood | haven't had Flu since. I also had the multivalent pneumonia | vaccine a while ago, so fingers crossed! | inglor_cz wrote: | TBH my last flu vaccine was something like 25 years ago (I | am not antivax, I am just too lazy to get it) and I had | "true" flu (not seasonal colds or covid) precisely once | since then. | | My doctor friend doesn't get flu vaccine even when | recommended, because, to quote her, "in my line of work, I | was already exposed to everything ten times at least". She | works as an ORL expert in a big hospital, so she is | constantly staring down some sick throats. | lawlessone wrote: | I try to get them when I remember. There's more evidence | , especially since Covid open peoples eyes, that colds , | flus etc can have long term effects even after they are | gone. | nolongerthere wrote: | Just to be clear, there is no vaccine for the common | cold, nor has there been any evidence, such as a properly | conducted study, to suggest a cold can have long term | effects. | UncleSlacky wrote: | https://www.sciencealert.com/long-cold-a-hidden-form-of- | chro... | nolongerthere wrote: | Interesting, I have many family members who work in | healthcare and all who are in regular contact with | patients are required, by hospital policy, to get the flu | vaccine annually. They would not be allowed to clock in | if they don't get vaccinated as its determined to be a | risk to the patients (the Dr or nurse can easily become | typhoid mary). | inglor_cz wrote: | Here, such policies vary even across a single hospital. | Some healthcare workers are required by law to be vaxed | against HepB or HepA, or measles, or rabies, but flu is, | nation-wide, only "recommended". | chimprich wrote: | > (I am not antivax, I am just too lazy to get it) | | Startup idea - vaccine delivery service. Pay a fee or | subscription and someone comes to your house or workplace | and jabs you with flu vaccine plus any travel shots | required. | dotnet00 wrote: | Funnily enough, this was the first year I got a flu | vaccine, because it was being offered basically at my door | and I thought it'd be useful to have before visiting | family. I still managed to get sick afterwards, just | instead of a flu it ended up being a particularly bad viral | cold. | | Not a slight against the flu shot, just a funny tidbit | since it reminded me that the vaccine doesn't make me | invincible from all similar disease. | justsee wrote: | While it's just an anecdote, it's more than just a funny | tidbit as an increased risk of non-influenza respiratory | virus is a possible side effect of flu vaccines. | | "We identified a statistically significant increased risk | of noninfluenza respiratory virus infection among TIV | recipients (Table 3), including significant increases in | the risk of rhinovirus and coxsackie/echovirus infection" | [1] | | That's one of the complications in assessing efficacy: if | the benefit in flu vaccine is potentially quite modest | (as determined by some long-running studies [2]), and it | causes an increased risk of other noninfluenza | respiratory viruses, then we need higher-quality, more | detailed studies to understand what's happening. | | But based on the discussion of the Cochrane review it | seems unlikely. [3] | | [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404712/ | | [2] https://www.cochrane.org/news/featured-review-three- | updated-... | | [3] https://community.cochrane.org/news/why-have-three- | long-runn... | lawlessone wrote: | nurses are a diverse lot. You meet plenty that could be | equivalent to or sometimes more medically experience than | doctors. | | And then unfortunately the one you met(who is probably | otherwise good at their job) | 2devnull wrote: | Same is true for doctors. Some good, some very bad. In fact, | the same is true (don't hate me for saying so) various other | types of pharmaceutical products, including vaccines that | rely on herd immunity and those that are merely "vax | treatments" or whatever they've renamed it to in late 2023 (I | think I was told that they are allowed to call it a "jab" or | a "spike vax" but not a booster.) | maxerickson wrote: | Are you relating a stupid thing a doctor said to you? It | isn't entirely clear. | epcoa wrote: | Someone is feeding you BS information. | dmd wrote: | > who is probably otherwise good at their job | | What would make you think that? | TeMPOraL wrote: | Because unless one's a researcher, their job doesn't | require a fully consistent set of beliefs. Being wrong or | even stupid about one area usually doesn't affect any other | areas - if it does, it probably means one's spending too | much time rethinking everything from first principles, when | they should've long ago developed a feel for it. | NateEag wrote: | Being a researcher doesn't require a fully consistent set | of beliefs. | | You do need to be willing to go where the evidence leads | you, but that doesn't require or guarantee a fully- | consistent belief system. | toomuchtodo wrote: | I recommend reporting them to their employer. If you don't | believe in the efficacy of vaccines, you don't belong in | healthcare. If you hold the belief outside of healthcare, | that's a right and a choice. | vasco wrote: | Flu vaccines are many times not effective. It's not like they | told them to skip a tetanus vaccine. I know it became a | polarised topic but we don't need to pretend like all | vaccines are the same. It's possible and likely to take a | yearly flu shot and still get sick: | https://www.cdc.gov/flu/vaccines-work/vaccineeffect.htm | | > CDC conducts studies each year to determine how well | influenza (flu) vaccines protect against flu. While vaccine | effectiveness (VE) can vary, recent studies show that flu | vaccination reduces the risk of flu illness by between 40% | and 60% among the overall population during seasons when most | circulating flu viruses are well-matched to those used to | make flu vaccines | | > How well flu vaccines work (or their ability to protect | against a certain outcome) can vary from season to season. | Protection can vary depending on who is being vaccinated. At | least two factors play an important role in determining the | likelihood that vaccination will protect a person from flu | illness: 1) characteristics of the person being vaccinated | (such as their age and health), and 2) how well the vaccines | "match" the flu viruses spreading in the community. When flu | vaccines are not well matched to some viruses spreading in | the community, vaccination may provide little or no | protection against illness caused by those viruses. | | Compare it with something like tetanus vaccines: | | > Today, diphtheria and tetanus are at historic low rates in | the United States. No one has ever studied the efficacy of | tetanus toxoid and diphtheria toxoid in a vaccine trial. | However, experts infer efficacy from protective antitoxin | levels. A complete vaccine series has a clinical efficacy of | virtually 100% for tetanus and 97% for diphtheria. | | https://www.cdc.gov/vaccines/vpd/dtap-tdap-td/hcp/about- | vacc... | | It's not crazy to behave differently around something with | 40-60% efficacy and something with 97-100% efficacy. | carbocation wrote: | There is steelmanning an argument, and then there is | completely changing it. | | There is a world of difference between having your | healthcare provider tell you "the flu vaccine has to be | made in advance and often targets the wrong strain, so can | therefore be ineffective even the majority of the time" vs | calling the vaccine putting "junk in [your] body". | vasco wrote: | I'm not sure what was so wrong about the reply, the | person I replied to said it should be a fireable offense | to "not believe in the efficacy of vaccines" but the | specific vaccines they were talking about have around | 40-60% efficacy vs 97%+ for other types. Maybe I'd agree | that they could be fired / reprimanded for addressing | such topics without more rigor (and not call them junk), | but the specific point I addressed I think wasn't | "changing the point". | toomuchtodo wrote: | Words matter. If you tell an unsophisticated healthcare | consumer a vaccine is junk, you should be fired. If you | provide efficacy around different types or classes of | vaccines and allow the healthcare consumer to make an | informed decision, that is reasonable. It is about the | information delivered and its delivery in significant | matters. | | Tangentially, there is no value in arguing with | antivaxxers or conspiracy theorists. You might as well | attempt to talk them out of their religion. Effort better | spent elsewhere. Regardless, informed consent must be | mandatory in a healthcare or medical setting, so the | patient can make a choice with all available information. | I am not arguing choice in this subthread. I'm also not | willing to argue vaccine safety data or statistics. | JumpCrisscross wrote: | > _not crazy to behave differently around something with | 40-60% efficacy and something with 97-100% efficacy_ | | Why is 50% less flu not a good thing? | | This is like the sterilising argument about the Covid | vaccine. It's somehow damning for the Covid jab but not for | polio. | TheBlight wrote: | Is it logical to assume all vaccines are equally well-made, | safe and effective? By calling something a "vaccine" do we | elevate it above all reproach? | thinkcontext wrote: | The remarks about "junk in my body" is a huge red flag. | That's blatantly unprofessional. | TheBlight wrote: | It lacks tack, IMO, but maybe there's a reason for their | comment. Doesn't seem like it hurts to ask someone why | they have their particular opinion vs. knee-jerk bucket | them into a stereotype we have imagined and completely | dismiss them. | Ekaros wrote: | So the Covid vaccines were sterilising and not single person | who got it got the Covid? If you believe that you should be | banned from participating in society in my mind. | JumpCrisscross wrote: | > _So the Covid vaccines were sterilising and not single | person who got it got the Covid?_ | | Per the article, sterilisation and total efficacy is not | even true for the polio vaccines. | | Could you imagine the histrionics we'd be facing if our | modern vaccines resembled the live polio vaccine, _i.e._ | the one that's actually sterilising? | o11c wrote: | Also, when the CIA doesn't ruin everything. | CodesInChaos wrote: | > On May 2, 2011, President Barack Obama announced that the | US Central Intelligence Agency (CIA) had located and killed | Osama Bin Laden. The agency organised a fake hepatitis | vaccination campaign in Abottabad, Pakistan, in a bid to | obtain DNA from the children of Bin Laden, to confirm the | presence of the family in a compound and sanction the rollout | of a risky and extensive operation. Release of this | information has had a disastrous effect on worldwide | eradication of infectious diseases, especially polio. | | > On May 16, 2014, the White House announced that the CIA | will no longer use vaccination programmes as a cover for | espionage. The news comes in the wake of a series of militant | attacks on polio vaccination workers in Pakistan, with | legitimate health-care workers targeted as being US spies. | The attacks have forced organisations such as the UN to | suspend polio vaccination efforts in Pakistan, and have | severely hampered anti-polio efforts, with parents refusing | to have their children vaccinated. News of the vaccination | programme led to a banning of vaccination in areas controlled | by the Pakistan Taliban, and added to existing scepticism | surrounding the sincerity of public health efforts by the | international health community. | | https://www.theguardian.com/world/2011/jul/11/cia-fake- | vacci... | | https://www.thelancet.com/journals/lancet/article/PIIS0140-6. | .. | danans wrote: | > News of the vaccination programme led to a banning of | vaccination in areas controlled by the Pakistan Taliban, | and added to existing scepticism surrounding the sincerity | of public health efforts by the international health | community. | | If I recall correctly, the conspiracy theory that emerged | was that vaccines were secretly being used to render the | people sterile. | | It is interesting how 8 years later nearly the same line of | thinking took hold in the West (albeit with claim of | injected mind control chips) amid anti-vaxxers. | krapp wrote: | >It is interesting how 8 years later nearly the same line | of thinking took hold in the West (albeit with claim of | injected mind control chips) amid anti-vaxxers. | | That line of thinking always existed in the West, among | the "Mark of the Beast" set. The interesting thing is the | degree to which it, and conspiratorial politics in | general, became so normalized in such a short time. Also | how the anti-vax movement switched from a generally | leftist ideology to being captured by right-wing identity | politics. | starcraft2wol wrote: | The parties have realigned around populism. | Mountain_Skies wrote: | Interesting how many people realigned their values | instead of changing their party loyalty. | starcraft2wol wrote: | Indeed, although some of the same groups still feel | supported but just not for the same reasons as before. | Kye wrote: | The actual program of sterilizing indigenous people and | experimenting on black people in the US sure didn't help. | | https://en.wikipedia.org/wiki/Sterilization_of_Native_Ame | ric... | | https://en.wikipedia.org/wiki/Tuskegee_Syphilis_Study | | Notions of conspiracy form easily when reality provides | so much material. | vGPU wrote: | Considering the United States forcefully sterilized some | 70,000 people, and that there is an ongoing investigation | over nonconsensual sterilization procedures being | performed by the government _three years ago_ , your | handwaving over "conspiracy theorists" is pointless. | | After all, it isn't like the government has a long | history of eugenics, forcefully drugging people for weeks | at a time with combinations of LSD, barbiturates, and | other fun stuff, right? | | Our government would never do that. | danans wrote: | > Considering the United States forcefully sterilized | some 70,000 people, and that there is an ongoing | investigation over nonconsensual sterilization procedures | being performed by the government three years ago | | Context is everything. The US government did that in the | context of their genocidal war against indigenous | peoples. There were fully transparent laws on the books | that rewarded people for murdering native populations. No | conspiracy needed. | | As for your claim from 3 years ago, you've thrown out an | allegation without providing any evidence. Involuntary | sterilizations likely do occur, but that's far from an | indication of a systemic government conspiracy. | | The context of COVID vaccines was a global pandemic, not | a genocide. | | Also, nobody has shown up at the hospital yet to discover | that their ailments were caused by a malfunctioning mind | control chip delivered in a vaccine. Defect rates for | such a "chip" if it existed would not be that low. | kian wrote: | "Three generations of imbeciles is enough" doesn't ring a | bell for you, eh? Those who don't read history... | vGPU wrote: | > Of the 7,600 women who were sterilized by the state | between the years of 1933 and 1973, about 5,000 were | African American. | | Stop lying. You come in with a false faith argument and | can't be bothered to research elementary facts. | bhk wrote: | One thing that boosts conspiracy theories is the | existence of conspiracy agencies in the government. | HorizonXP wrote: | Yeah I remember hearing about this and being similarly | appalled. I get it. The US really wanted to kill Bin Laden. | But the manner in which they did it is sickening. | | The ends cannot justify the means. | SpaceManNabs wrote: | > The ends cannot justify the means. | | Oh they absolutely can in an utilitarian sense. But a | basic utilitarian argument would tell that jeopardizing | an entire region's vaccine rollout program to get revenge | on some asshole already living the rest of his life out | of a hole was not worth it. | NateEag wrote: | And any utilitarian thinker who wanted to do the op would | tell you that they weren't going to get caught, so that | outcome won't be relevant to their calculus. | | Is that good reasoning? No. | | Is it what some humans will do? Yes. | TheBlight wrote: | Given she's a health care professional I'd probably follow up | with her for more of her reasoning. Has she seen it fail | clinically? Is she aware of any adverse side-effects? Is it an | issue with this specific brand? | iamflimflam1 wrote: | Health care professional covers a huge range of people. This | is not in any way meant to dismiss the incredible hard work | that these people do, but health care is a notoriously low | paid profession and many people have little to no | qualifications. If you are assuming the "health care | professional" equates to informed and well trained then I | have a bridge that you might be interested in... | vGPU wrote: | > health care is a notoriously low paid profession | | Where is that, exactly? Because it certainly isn't in the | US. | dartos wrote: | It depends where in healthcare. | | Geriatric nurses tend to not get paid well, but resident | nurses in hospitals do. | | It's a wide field. | Tagbert wrote: | Surgeons and specialists are high paid. Regular | physicians not so much. Nurses are not at all highly | paid. | vGPU wrote: | As a nurse I make $100/hr. | | Try again. | mikeyouse wrote: | You must be in California.. in many states, RNs are | making more like $15/hr and BSNs closer to $20-$25/hr. | vGPU wrote: | No, I'm not. Nor am I in any of the other high paying | states you might name. | nradov wrote: | Median annual wage for a Registered Nurse in the US is | $81K. That is way higher than the national average worker | income of only $54K. | | https://www.bls.gov/oes/current/oes291141.htm | iamflimflam1 wrote: | In the UK nurses appear to start around PS22K | https://www.nurses.co.uk/careers-hub/nursing-pay-guide/ | TheBlight wrote: | Every profession has a spectrum of quality of worker. Any | health care professional is more experienced than me. What | does it hurt to follow-up for clarity? Her rationale may be | completely unconvincing and that's fine I can then ignore | it. Or she might tell me something interesting I can keep | in mind and see if it gets corroborated by other sources. | Izkata wrote: | > Has she seen it fail clinically? | | Flu vaccine efficacy has been <50% for over a decade. Usually | it floats around 30-40%. So even by the official numbers, it | doesn't do a lot for groups not really at risk. | | This is not a surprise: The yearly shots are for a subset of | flus, created in the spring/summer for the strains they think | will be most prevalent in the fall. | xkbarkar wrote: | That did not happen. Uff tiresome to read the conspiracy crap | on vaccine usage, all of a sudden even nurses are anti-vaxxers | (or whatever rage inducing crap gets comment votes these days). | I am stating the comment is for internet points only and never | happened and Id bet money on it. | Kiro wrote: | > politically weaponized by AI | | What is this referring to? | thinkcontext wrote: | You should report the nurse. They could be doing real damage to | community health. | tambourine_man wrote: | I would report her to the responsible in the hospital and to | the regulatory agency in your country. | | I did it twice during the pandemic. In one case it was someone | I trusted for many years. | xkbarkar wrote: | This comment is solely to collect internet points. Never | happened. Id be money on it. | 2OEH8eoCRo0 wrote: | My partner works with a lot of nurses and some of them say | things that are this uninformed. | bunabhucan wrote: | I've done pro vaccine advocacy work like testifying as a | parent at bill hearings. The anti vaccination folks | testifying include nurses and will be very loud about that | fact. We've also had problems where a nurse doing pre natal | classes turned put to be anti vaccine. | syedkarim wrote: | Was this a registered nurse (4-year nursing degree)? | kevin_thibedeau wrote: | Maybe she was confused with Tamiflu which only works when | administered no more than 48 hours after onset of symptoms, at | which point there can be no certainty it's an influenza | infection at all without the expense of testing. | phpisthebest wrote: | Calling it a vaccine (like COVID vaccine) is a problem IMO | | Non-immunizing treatments should not be called vaccines, the | annual flu shot should not be considered a vaccine, nor should | the mRNA COVID "vaccine", for which they had to change the very | definition of what a vaccine is to even include it for legal | purposes. | | For the flu shot it is a crap shot, as there are soo many flu | variants annually they make a best guess as to which one(s) | will likely because prominent based on trends and package them | up, often they are correct sometimes they are not... | | For more traditional vaccines like Polio and other long term | immunizing vaccines society ends up suffering because of the | inclusion of these short term annual or less treatments and | over all is a net negative | | As to " politically weaponized by AI and social media | algorithms" it was more than AI and Social media that made | these things political, it was the political branches of | government that made it so by mandates and rhetoric that pitted | people against each other. Attempting to exile people that even | questioned their government masters... That is what made it | political. | samatman wrote: | The problem is that they are vaccines, "vaccine" doesn't mean | what you think. | | The best vaccines are sterilizing, meaning that they prevent | disease and transmission often enough that very high rates of | vaccination extirpate the virus. | | It might be useful for discussion purposes if "vaccine" meant | "sterilizing vaccine" and vaccines which don't work as well | had some other name, but that's not how it works. | phpisthebest wrote: | >>"vaccine" doesn't mean what you think. | | yes they keep changing the definition to include more and | more things legally as "vaccines" are shielded from any | liability so you can not sue big pharma if they injury with | their "vaccine" | | this however does not change the fact that the way the law | (and you) use the term is very very very different than | what the ordinary person thinks and understands a vaccine | to be | | When this person then discovers that the government uses a | different (your) "correct" definition to include things | they traditionally would not think of as a vaccine this | erodes trust in the entire system. | | This was made very very clear with COVID. | mikeyouse wrote: | Nobody changed any definitions - laymen started becoming | interested in the topic due to obvious reasons so the CDC | and others clarified some publicly facing websites but | nobody involved was remotely confused about the vaccines. | JumpCrisscross wrote: | > _Non-immunizing treatments should not be called vaccines_ | | What do you consider immunizing? | Nextgrid wrote: | > it was more than AI and Social media that made these things | political, it was the political branches of government that | made it so by mandates and rhetoric that pitted people | against each other | | But social media did wonders at spreading & amplifying that | message, since pitting people against each other in endless | arguments generates lots of "engagement". | jfengel wrote: | If it doesn't contain cowpox it's not a vaccine. Definitions | are always strictly limited to their first use, and must be | studiously maintained or we'll destroy the English language. | JumpinJack_Cash wrote: | > > I just had a nurse tell me yesterday to not take the flu | vaccine because she said it doesn't prevent flu | | The flu vaccine is notoriously kinda like shooting in the dark | because it's hard to predict which strain will dominate the | winter. | mikeyouse wrote: | The flu vaccine has upwards of a 30% reduction in all cause | mortality in at-risk populations. It's insanely effective | even when the chosen variants aren't ideal. People are so | ridiculous, they'll get a flu vaccine, contract a flu that | makes them pretty sick and then decide that the vaccine | didn't work rather than realizing it did work and saved them | from a much worse illness. | CodeWriter23 wrote: | https://polioeradication.org/polio-today/polio-now/ | tomohawk wrote: | From the article, wild polio cases have been less than 50 per | year for the past 3 years, but vaccine derived cases have been | 300 - 900 per year. The details in the article as to why this is | are interesting and alarming. | | It just shows that a lot can go wrong in this process and good | intentions are not enough. | SketchySeaBeast wrote: | Well, during the 80's there were 300,000 to 400,000 cases | worldwide per year[1], so I have a hard time seeing how this is | bad thing. | | [1] https://ourworldindata.org/polio | User23 wrote: | It's a bad thing for the hundreds of children crippled every | year. Eradication means those vaccine injuries go away. The | hundreds of persons a year who would otherwise be crippled | see it as a very good thing I expect. | | Edit: to all you religious fanatics who can't stand the idea | that your Science Sacrament can ever be harmful, the oral | Poliovirus vaccine contains live virus and very much can and | does cause polio in the persons receiving it in some cases. | JumpCrisscross wrote: | > _those vaccine injuries_ | | If you're vaccinated against polio, the vaccine-derived | virus can't harm you. The people being injured are by and | large the unvaccinated. | gwervc wrote: | Circular logic. Vaccines can injure people, it's a fact. | I've seen it first hand with a relative of mine get an | hepatitis from a vaccine. Trying to silent that just | foster conspiracy theories, because once trust is lost | it's hard to rebuild. So better not lose it by hiding | scientific and medical facts. | JumpCrisscross wrote: | > _Vaccines can injure people_ | | Nobody said otherwise. | | What's being contested is the framing of those who are | getting vaccine-derived polio as vaccine injured. They're | not. They're side effects of the sterilizing polio | vaccine. If they were vaccinated, they wouldn't have been | injured. | | > _silent that just foster conspiracy theories, because | once trust is lost it 's hard to rebuild_ | | Nobody is silencing anyone. We're in an era of the | opposite of silencing. | | It's increasingly clear there is a psychographic or | political profile that will not get vaccinated, facts be | damned. I don't think they should be forced to. But they | shouldn't be allowed into the healthcare profession, and | they should be restricted from public spaces in | healthcare crises. (Countries should also be free to | restrict them from entry.) | samatman wrote: | This is wrong even on its own logic, which is | circular/bad. | | Someone who gets polio from an oral polio vaccine _is | vaccinated_. That 's how they got the infection: from | vaccination against polio. | JumpCrisscross wrote: | > _Someone who gets polio from an oral polio vaccine is | vaccinated_ | | Vaccine-derived polio cases are _not_ in the person who | got the oral polio vaccine [1]. | | The vaccine recipients are vaccinated. But they can | spread that live, attenuated virus to others. If it keeps | spreading--among the unvaccinated or IPV recipients--it | can mutate and become dangerous. Eventually, dangerous | enough to cause polio. | | But only to the unvaccinated. The original vaccine | recipient isn't injured. They got the attenuated virus. | And nobody vaccinated around them is injured, either. | It's solely the unvaccinated around them who got the | monster that virus mutated into. | | [1] https://www.npr.org/2019/11/16/780068006/how-the- | oral-polio-... | SketchySeaBeast wrote: | I agree, it is and would like it to be eradicated. But it's | hard to argue that the vaccines are worse than no vaccines, | right? Do you believe the conditions would get better or | worse if we stopped vaccinating? I can see polio returning | to its previous numbers, and to me, that's objectively | worse. | | Feels like we're rejecting good because it's not perfect. | JumpCrisscross wrote: | > _details in the article as to why this is are interesting and | alarming_ | | Why is it alarming? The sterilising vaccine produces vaccine- | derived polioviruses. The non-sterilising type does not. | | First you sterilise, then switch to non-sterilising as the wild | type is eradicated. It's a precedented playbook which makes it | the opposite of alarming. | dopylitty wrote: | Polio virus isn't close to eradication and people who work on it | are coming to the conclusion that it probably never will be | unless a different sort of vaccine is created. [0] | | Polio the disease caused by polio virus could be eradicated with | widespread and continuous vaccination. | | The problem is the current vaccine used in most places around the | world is an attenuated live virus vaccine. | | It gives the recipient immunity by infecting them with a strain | that doesn't cause disease in most people but is still able to | replicate in the gut and spread to others and eventually reverts | to being able to cause disease. So anyone who isn't vaccinated | can still get the reverted vaccine strain. The most common cause | of polio outbreaks now is the vaccine strain. | | In rich countries they use an inactivated vaccine that works | great against disease and can't become virulent but is expensive, | requires more infrastructure for delivery (needles etc), and | doesn't give enough immunity to prevent spreading the virus if | infected. | | There are possible solutions to all of these problems but they | require research and the eradication campaigners are making | research more and more difficult by restricting which labs can | work on polio research. | | The podcast TWiV is hosted by the guy who first figured out the | Polio virus genome and they frequently discuss it. The episode | below is about a new attenuated vaccine that was recently created | with hopes of not reverting but even it has reverted in some | small number of cases. | | 0: https://asm.org/podcasts/twiv/episodes/driven-to- | immunodistr... | readams wrote: | All of that, and the strategies used to combat it (including a | better oral vaccine), are described in detail in the article. | jsbisviewtiful wrote: | How dare you assume someone who didn't read the article and | then unknowingly posted contents from the article didn't read | the article lol | HorizonXP wrote: | If it helps with the pain of downvotes, I appreciated your | sarcasm. | dopylitty wrote: | Both the headline and the article imply that eradication is | possible. Being "on the brink" even makes it sound | inevitable. But eradicating the virus probably isn't possible | and I think it's important for people who only read headlines | and comments to understand that and why it's the case. | JumpCrisscross wrote: | > _eradicating the virus probably isn 't possible_ | | Every domains expert disagrees. That most people get the | non-sterilizing IPV is not a secret. Switching from the | sterilizing, but virus-producing OPV to the non- | sterilizing, but non-spreading (and more expensive) IPV is | a well-run playbook. | | Yes, it means when an unvaccinated nutter from Brooklyn | gets polio in Europe [1] that it spreads--inefficiently and | without further consequence--through the vaccinated | population. But those are edge cases which are diminishing | in frequency as we switch from OPV to IPV on the periphery. | | First we eradicate the wild type. Then we eradicate the | weaker vaccine-derived virus. It's a simple, precedented | and achievable playbook. All we have to do is keep | vaccinating (and keep our poop water away from our drinking | water). | | [1] https://www.cnn.com/2022/07/21/health/new-york- | polio/index.h... | HorizonXP wrote: | Apt. Took the kids for vaccinations this morning and was telling | kiddo last night about how amazing vaccines are and how polio | doesn't exist anymore because of it. Sounds like I was | technically wrong, but practically right. | | I also told him how amazing it is that when I was his age, I had | the chickenpox, but that he will never get it because they | developed a vaccine for it. | | None of this helped him today with not freaking out over getting | a shot, but hey, I tried and I made it clear why I had to hold | him down. Sometimes, irrational fears win. We'll get there, he's | just a kid. | gr2m wrote: | My kids are into superheros. We explained how vaccines are | basically super powers! Now they are sad when they go to the | doctor and don't get one they also get all their friends and | class mates pumped about vaccines which I take as a win | JumpCrisscross wrote: | In a real sense, vaccinations _are_ superpowers. Immunity | from pestilence was historically taken, across cultures and | for obvious reasons, as signs of divine influence. | Modified3019 wrote: | I had no idea there was a chicken pox vaccine. That's awesome. | ChrisMarshallNY wrote: | _> Only one human disease has so far been declared eradicated: | smallpox_ | | I was reading a post by someone, a few years ago, lamenting that | we had "killed" a virus. | | I am not 100% sure they were being serious, but they gave every | indication that they were. | | In any case, I'm sure that some bioweapons lab, somewhere (like, | maybe, in Frederick, MD) has samples of the virus, "just in case | it comes back." | nolok wrote: | Don't need to wonder, the US and Russian (Soviet at the time) | have made it public that they keep samples of smallpox. | | https://en.wikipedia.org/wiki/Smallpox_virus_retention_debat... | ChrisMarshallNY wrote: | I'm old enough to have a smallpox vaccination scar on my arm. | dghughes wrote: | I never got one since the doctor didn't like the look of a | birthmark on my arm. I don't have that puffy scar. My | sister got one though. | | Damn I just though I could have been a left arm bicep | model. | ls612 wrote: | Ostensibly this serves a purpose beyond the MAD incentive, | having stocks of the virus on hand makes manufacturing the | old style smallpox vaccine easier should the need ever arise | in the future. As we saw with monkeypox last year there is | much more limited capacity for more modern pox vaccines due | to the more advanced manufacturing process and limited | demand. | naravara wrote: | Someday soon we'll just be able to sequence its genome and | reconstruct it without needing to keep samples alive (and | no longer have the risk with all the maintenance and | security protocols that will entail). | | Of course however we store that genomic code had better be | on physical media in a sealed vault that isn't even within | spitting distance of anything with an internet connection. | Gare wrote: | https://thebulletin.org/2020/02/a-biotech-firm-made-a- | smallp... | kbenson wrote: | Yeah, as you allude to in your parting sentence, I'm not | sure if this idea makes me more or less secure. Chance | for accidental infection at the storage facility goes way | down, but should the sequence ever leak to the internet | chance for accidental infection from some stupid amateur | biohacker goes _way_ up in my opinion, and that 's before | we get to purposeful infection. | | If it's going to be preserved, I think I'm happier with | it not being digital and stored in highly secured areas | by professionals, but perhaps the threat model in my head | isn't accurate enough. | Turing_Machine wrote: | > Someday soon we'll just be able to sequence its genome | and reconstruct it without needing to keep samples alive | | That's already been done, I think. | vgel wrote: | Oh, we already sequenced it awhile back. As for physical | media, that's not exactly what happened... https://www.nc | bi.nlm.nih.gov/nuccore/NC_001611.1?report=fast... | anon84873628 wrote: | Well, there are still 12 other viruses in the genus (including | one newly discovered in 2015 and the monkeypox outbreak of | 2022-2023) so I think we are still good on source genetic | material. Still possible for one of those species to evolve to | be more virulent and deadly... | samatman wrote: | Many variations of the full genome are available online, and | current technology makes it feasible to synthesize de novo. | | Just in case you didn't have enough things to worry about! | bushbaba wrote: | Keeping samples is honestly a good thing as it allows for | further research into the virus should it ever mutate and come | back. | BurningFrog wrote: | The sacredness of every species is a fundamental belief for | many people! | verisimi wrote: | Banning chemicals from food, eg ddt, surely helps. | JumpCrisscross wrote: | > _Banning chemicals from food, eg ddt, surely helps_ | | No? | huytersd wrote: | The hell are you talking about. This is a viral infection. | verisimi wrote: | What do you think I'm talking about? I would be more clear, I | could say more, but I'm already riding a line around here. | | All I'd say is: we are told this or that, viral infection, | vaccines, etc... but how does one confirm any of it? Must one | take pharmaceutical companies or their related organisations | (WHO, Nature) at their word? | JumpCrisscross wrote: | > _how does one confirm any of it? Must one take | pharmaceutical companies or their related organisations | (WHO, Nature) at their word?_ | | No. But it takes some effort. | slackfan wrote: | We've been on the brink of eradicating polio for something like | 60 years. | | And then vaccine manufacturers across the world fuck up and cause | an outbreak. | | This is one of those cases that I have no sympathy for the hype | piece, no sympathy for "the science", or the pharma companies | making bank off of keeping this thing rolling. Only sympathy goes | out to the people hurt by polio and human idiocy. | JumpCrisscross wrote: | > _then vaccine manufacturers across the world fuck up and | cause an outbreak_ | | What? | DoreenMichele wrote: | In recent decades, infection from vaccines based on the live | virus, instead of the killed virus, has been a primary source | of outbreaks. The usual mechanism: Someone who was never | vaccinated changes the diaper of a child who has gotten the | live vaccine, gets exposed, gets sick. | | Many years ago on _Sixty Minutes_ , an elderly man who | changed the diaper for his grandchild caught it and diagnosis | and treatment was delayed because the doctor literally said | something like "Decades ago, I would say this was polio. You | have all the symptoms." and didn't consider that was possible | because "we've eradicated it." | JumpCrisscross wrote: | How is that vaccine manufacturers fucking up? Also, this is | literally what this article is about. | | (And we use the non-sterilising, non-virus containing non- | polio-producing IPV in the United States. So the | unvaccinated can change babies' diapers without fear.) | DoreenMichele wrote: | I'm not suggesting it is. But "What?" is hardly a | rebuttal a la "That's not a fuck up." So I explained what | I think the OP likely is referring to because you sounded | to me like you had no idea what they meant. | Izkata wrote: | > (And we use the non-sterilising, non-virus containing | non-polio-producing IPV in the United States. So the | unvaccinated can change babies' diapers without fear.) | | Not necessarily. All those migrants coming into the | country? Mostly they got the cheaper OPV vaccine, if they | got any. There was a case of it last year in New York: | https://www.cdc.gov/vaccines/vpd/polio/hcp/vaccine- | derived-p... | flatline wrote: | https://www.theatlantic.com/health/archive/2022/09/polio- | era... | chihuahua wrote: | I'm not sure what exactly GP is referencing, but maybe it's | the rare cases when the weakened virus in OPV mutates and | someone excretes infectious, vaccine-derived poliovirus. I | still don't see how that's the fault of the vaccine | providers, since it's due to mutation and not a mistake in | production of the vaccine, and OPV is a reasonable thing to | use and certainly better than doing nothing. | cyberax wrote: | DON'T JINX IT!!! | | I've been visiting https://polioeradication.org/ over the years, | and every time I get my hopes high, discover more polio cases or | polio-positive samples are discovered :( | | They have a regularly updates summary: | https://polioeradication.org/wp-content/uploads/2023/11/week... | | And the most recent case was on Oct 15 in Pakistan. | mcstafford wrote: | I suspect science has had more to do with the reduction than | superstitions like jinxes. | bendbro wrote: | I pray to god people let go of their superstitions. | kbenson wrote: | Some people play lip service to superstitions like this as a | form of fun or a way to communicate feelings on a topic, and | not necessarily because they believe the superstitions. | | For example, if I followed up a statement with "knock on | wood" it wouldn't be because I believe it helps, or expect | anyone to actually take that physical act (I probably won't | unless to emphasize my feeling more), it's to convey I hope | something succeeds or does not fail in a way that provides a | lot of context in a small amount of words. | cyberax wrote: | Jinxing means you hat people might consider the problem | solved and pay less attention to it. | DoreenMichele wrote: | Their imagined future resurgence scenario -- someone in a lab | gets infected, then travels abroad -- highlights one of the | reasons developed countries need to help less developed | countries: Out of enlightened self interest, not "charity" nor | "the goodness of their hearts." | | We currently are de facto breeding antibiotic resistant | infections in places without adequate sanitation or water | infrastructure and you can go from pretty much anywhere on the | planet to pretty much anywhere else these days in 24 hours or | less. When people from developed countries get sick while | someplace else, they are often medevaced out to get them good | care in a modern facility, thereby potentially exposing people in | their country to whatever they have. | | We need to do a better job of providing basics like adequate | water infrastructure worldwide if we want to be free from such | diseases in our cushy developed countries. | genman wrote: | We must collectively understand the reason why some countries | stay "developing". The reason is very simple - the rate of | population growth exceeds the rate of infrastructure | development by large margin. You can make large investments and | build everything for 1 million people, but after two decades | there are now 2 million people and then 4 and then 8. Africa | started out with 200 million people After the WW2 period. In | the beginning of this century there were around 800 people. Now | there are 1.5 billion people. The rate of population growth is | just unbearable. And Africa is here just an example. The same | problem affects also India and other places. | DoreenMichele wrote: | Malawi is one of the countries mentioned in this article as a | source of polio outbreaks. A famous singer has invested | millions in hospitals there and they still lack adequate | water infrastructure. I imagine their post operative stats | are probably not great. Getting surgery in a modern hospital | and going home to inadequate clean water and inadequate | nutrition likely actively fosters post operative infections. | | Population growth tends to stop with adequate education plus | reproductive rights for women. Development isn't just about | infrastructure. It's also about culture, education, | developing the local population so they can sustain a more | developed society. | | My recollection: water.org was started by a man who went to | Africa with a medical charity, concluded that a lot of the | health issues they were treating were directly caused by lack | of clean water, decided _we should fix that._ | | We already invest in other countries, just not necessarily | wisely. Advanced surgery being brought to primitive | conditions is more about people wanting to feel heroic than | about really improving things. | BariumBlue wrote: | The Malthusian argument is incorrect and I disagree with the | concept of physical infrastructure being the end-all-be-all. | Japan, South Korea, Germany, as well as the USSR had | explosive growth after WW2 not because they had massive | existing infrastructure, but because of social systems & | processes that enable a reliable, stable, productive society. | | If the societies are fragile (vulnerable to drought, markets, | or violence), or rotting (corruption, superstition, | tribalism), even great infrastructure can make for subpar | growth. | | An analogy I always think of are Wadis (dry riverbeds); in | very dry places with little rainfall (like Hudaydah in Yemen | / Saudi Arabia), when it DOES rain, the dry dirt riverbeds | don't soak up any water and transport it all out in flash | floods - but it IS possible (and has been done) to invest in | the land's ability to hold that water rather than purge it. | Similarly, in a "always-developing" society, there'd have to | be a investment in the people to ensure they can benefit from | solutions to their issues. | epicureanideal wrote: | I don't think they're making a Malthusian argument. It's | about the difference in the rate of change or two | variables, not the absolute carrying capacity of a set of | resources as in the Malthusian argument. | epicureanideal wrote: | Although some might be interpreting the previous poster as | having some bad motives for saying what they're saying, it | does seem to be objectively true that population growth in | developing countries is absolutely huge. If the population | level had remained the same as 50 years ago the level of | development would be much higher. But of course the | population growth rate is declining so standards of living | should hopefully start to catch up. | genman wrote: | Yes and no. This is my argument indeed that if the | population growth stayed lower then a lot more people would | have been able to rise above the poverty level (or even | much higher). | | UN prediction for Africa is that they fall close to the | reproduction threshold for the end of century. Until that | the poverty trap will continue. It also means that by that | time now 4 billion people require their needs satisfied | instead. | | But the population growth has been huge and exponential. | From 200 million to 4 billion in 150 years is an incredible | amount of growth. | andrewmutz wrote: | That's not the reason that nations stay "developing". Nations | stay "developing" due to extractive economic and political | institutions that prevent economic growth. Great book about | the topic by economist Daron Acemoglu ("Why nations fail"). | | The reason that countries that have high population growth | tend to be poor is because when a country gets rich its | people have fewer children. The high fertility rate does not | cause the poverty, instead its the other way around: the | poverty causes the high fertility rate. | genman wrote: | I can't agree with this unfortunately. While getting rich | further lowers the fertility rate then there is a certain | threshold that must be first exceeded to get rich | (relatively speaking of course). | | There must be a feedback loop that incentivizes to get | better education, to get better productivity to get richer. | Raising a child is expensive, raising a highly educated | child is very expensive. If you have 8 children then you | can barely feed them unless you are very rich indeed. Even | if you manage to provide good education for few of your | children then the larger part of them continues the poverty | loop. Breaking out of poverty requires breaking of this | loop. | | It should be very obvious - if your economy grows 5% but | your population grows 10% then everybody is getting poorer | as the growth per capita is negative. The same applies for | everything, education, sanitation, food production. If you | capacity to provide any of them is lower than the | population growth then the amount of the poor continues to | increase. | DoreenMichele wrote: | And providing more basics, like improved agriculture, | education and essential infrastructure like clean water | access, is a better means to combat that issue than | sending in surgeons to play hero and have a feel-good | moment without making any real difference in the root | causes that led to someone needing surgery. | genman wrote: | Current problem in Africa is that their capacity to | produce food, while it is increasing relatively fast, | doesn't increase enough to keep up with the population | growth. This is why Russia can play with the grain | shortage to begin with. | DoreenMichele wrote: | I don't think we really disagree per se. Not sure why you | seem so adversarial. | | And Russia is probably not playing with the grain | shortage. They had an agreement in place to let the | country they are at war with sell grain because it's so | critical. | | It's probably more complicated than that and a tangent. | genman wrote: | No, I don't think that I provided a counter argument but | rather a supplementary one. Population growth rate is a | huge problem that hinders capacity to provide enough aid. | | Russia certainly used the risk of hunger as a weapon to | increase political pressure on Ukraine on the | international level. Fortunately that attempt didn't play | out and Russia was instead pressurized to make | concessions. But they stopped the agreement the same | moment they thought that it is not beneficial for them | anymore. But this is just a side topic and was given as | an example how the African incapacity to keep up with the | population growth has wider geopolitical implications. | teddyh wrote: | > _why some countries stay "developing". The reason is very | simple - the rate of population growth exceeds the rate of | infrastructure development_ | | Opinions are divided: | <https://www.youtube.com/watch?v=xP8CzlFhc14#t=3m> | genman wrote: | Yes, the communist argument - everybody else is at fault | but not myself. Yet the communist paradise, the 1/6 of all | the land with incredible riches stayed poor and finally | collapsed. | harshalizee wrote: | Also forgot the part where India and North/West African | regions were incredibly wealthy in the past and were | basically strip mined by colonialism. It's been only 50 years | or so that they're trying to catch up. | OfSanguineFire wrote: | West Africa was never "incredibly wealthy". Yes, before | Europeans it was part of long-range trading routes with the | Muslim world, but empires were feudalistic and only a tiny | elite had access to that trade-related wealth, while the | vast majority of the population was barely surviving | through subsistence farming and pastoralism, just like so | many do today, or hunting and gathering. | boxed wrote: | This is the same reason rich people should put a ton of their | resources into basic science, tech, and health infrastructure. | mptest wrote: | And since philanthropic approaches to such aspirations | demonstrably do not work, we need extremely high taxes on the | ultra wealthy. | | Before the six-seven digit earning engineers here lambast me, | I'm talking billionaires. | | No one intelligent can/has yet looked me in the eye and told | me earnestly: anyone with a billion + $ would have a single | degree lower quality of life if their wealth was capped at | 999 million | | If you want empirics google "highest marginal tax rate 1950- | present" and "infrastructure spending 1950- present". | weaksauce wrote: | billionaires existing is an indictment on our greed and | failures of our systems. nobody needs 1000+ million | dollars. | gwd wrote: | You're confusing _resources they have control over_ with | _resources for their own personal utilization_. Money is | power; not to force someone to do what they don 't want | to do, but to _pay_ them to do what they 're _willing_ to | do. When capitalism works well, it 's because people who | made "good" choices with their money-power were rewarded | with more, and people who made "bad" choices were | rewarded with less. | | Warren Buffet doesn't have an extravagant lifestyle. He's | been entrusted to make decisions about how to spend our | economy's resources in part because he's made good | decisions in the past. | | Obviously it doesn't always happen this way; but the | accumulation of wealth _by itself_ isn 't necessarily | bad. It's bad when it can be accumulated by ways which | destroy value for society rather than creating it; and | it's bad when it can continue to be accumulated by doing | nothing. | mptest wrote: | >You're confusing resources they have control over with | resources for their own personal utilization | | I don't know if they're as different as you portray in | practice. I agree with the notion in theory, which is why | I distinctly used "wealth" in my original comment and not | "income". | | >He's been entrusted to make decisions about how to spend | our economy's resources in part because he's made good | decisions in the past. | | Sure, no one is saying don't aspire to a meritocracy when | considering control of the state's purse strings. | | The key to your example and your "accumulation of wealth | by itself isn't necessarily bad" notion is the reason I | didn't say "no organization" should have more than 999m. | I was strictly referring to excess personal accumulation | of capital. Which harms us all. | | Like I said, no one's quality of life is going to get | worse if personal wealth were capped at 999m, but I can | think of infinite ways to make a lot of people's quality | of life better with the money we'd have in such an | organization of the economy. | | >and it's bad when it can continue to be accumulated by | doing nothing | | I don't even know if I agree with this. A state fund that | earns interest and spends that interest makes sense. I | think the key is the first case you note where it's bad. | rpmisms wrote: | So, the state should control any large enough corporation? | Or there should be a ban on over $999m in cash? Or should | the government just not waste the absurd amounts of money | we already give them? | mptest wrote: | >state should control any large enough corporation | | Not necessarily, company could be broken down in to | smaller, become employee owned in some part, could have | some amount of stock become owned by an infrastructure | fund or something. There's many ways to skin a cat | wingworks wrote: | I'd love for this to work, but in practise I feel the | owner on the 999m will more likely stop investing in sed | company when it reaches 999m and spin up a new company or | some other loophole to get around it. (or if it's | individual wealth, then they'll use trusts or some of the | many other options available to them.) | | If there are no options, you better believe they'll | create them soon enough. | mptest wrote: | >or some other loophole to get around it. (or if it's | individual wealth, then they'll use trusts or some of the | many other options available to them | | Completely agree, it will always be a cat and mouse game. | But it's a worthy aspiration, and I'd argue the reason | the wealthy have been the cat more than the mouse in the | relationship with the state is due only to the budget | disparity between them. | | Start to shrink the disparity between the enforcement | budget (think IRS special forces for the ultra wealthy) | and the "avoid taxes" budget and the aspiration looks a | lot more doable. | | >owner of the 999m will stop investing | | Maybe. Or maybe they'll get better and spending rather | than hoarding and continuously need to replenish that | stock. | | Even if these "winners" of a more 'social capitalism' | stopped gracing us with their genius, the surplus of | wealth in endeavors like free stem schooling for everyone | (that wants it) would surely make up for that loss?? | robertlagrant wrote: | > Not necessarily, company could be broken down in to | smaller, become employee owned in some part, could have | some amount of stock become owned by an infrastructure | fund or something. There's many ways to skin a cat | | If you think taking money from paper billionaires is | going to make a material difference to the US's $6 | trillion spending each year, can you quantify how much | are you expecting it to raise? | mptest wrote: | You're right that reducing spending, particularly the | pentagon's blank check and the military budget is going | to play a larger role but stop reading ahead! I can only | push leftist politics one point at a time out here! | PoignardAzur wrote: | > _And since philanthropic approaches to such aspirations | demonstrably do not work, we need extremely high taxes on | the ultra wealthy._ | | Pretty bold to claim that government intervention post- | taxes would work better than philanthropic fundations. | mptest wrote: | Is it bold? What percentage of all of our modern | infrastructure is from the benevolence of | philanthropists?? I am sure it's not zero, but I can't | imagine it being a majority... But please enlighten me. | For "billionaires know best what to do with all that | wealth, they'll take care of us" sounds an awful lot like | what sbf was preaching. | robertlagrant wrote: | This reasoning doesn't seem very sound. Infrastructure is | far too broad, to the point of irrelevance. "Sounds like | SBF" is also not reasonable. | | How about this: the state is bad because it declares war | and sends people to their deaths. Its projects often go | astonishingly over budget, corruption is high in many | countries, and its funding is unreliable, as it's prone | to not keeping the promises of the people previously in | charge. | | That accurately describes almost every state that ever | existed. If you have a similar list for all philanthropic | institutions, that would be a good start in justifying | your claim that philanthropy doesn't work, so we have to | take the money and let the bureaucrats handle it. | mptest wrote: | >the state is bad because it declares war and sends | people to their deaths | | Wouldn't it make more sense to conclude war is bad, | rather than states themselves? | | >Its projects often go astonishingly over budget, | corruption is high in many countries, and its funding is | unreliable, as it's prone to not keeping the promises of | the people previously in charge | | All of this I agree with. But the solution isn't "less | states" it's... Better states, surely? What am I missing | here? | | My point with the question about where a majority of our | infrastructure comes from, (roads, schools, hospitals, | water, electricity and sewage systems to specify as a | start) the state or the benevolence of philanthropists | was to demonstrate that there is quite a bit of evidence | as to what structure is the better steward of societies, | a bunch of rich guys, or a state with some mandate to do | right by its constituents. | renegade-otter wrote: | Alas, spending their untold riches to make the government | _better_ is not in vogue. Never has been. | | Instead, their mission is to gut governments, "burn it all | down" for the sake of eradicating those cursed regulations, | in the name of making the government "more efficient". In | reality it just means "get those pesky bureaucrats out of my | way of making even more money with immoral, destructive, and | even illegal ways". | | Instead we get "effective altruism" which basically means - | "my mission is to get as rich as possible in unholy ways, and | if you are lucky enough to be within the gravity field of the | pet causes I happen to be a fan of, then you get some money". | | You cannot find a worse way of a _civilized_ way of | distributing money to those in need. It 's ineffective by | definition. | | People need to remind themselves once in a while that the | world like this already existed. A bunch of feudal lords | running around, trying to get favors with the king. Most | people suffered, and rivers of blood were spent to shed that | kind of system to create, you know, a _civilization_. | | So stop worshipping the ultra-rich - they are the most | destructive anti-civilization force were are dealing with | right now, unleashing their wrath if they are not adored | enough, stewing in anger and grievances. | | And no, I am not saying Capitalism is bad. Sure, greed is | good and all that, but running amok and without any | oversight, it leads to no good. | claytongulick wrote: | > stewing in anger and grievances | | It seems as if the targets of your ire are not the only | ones in the stewpot. | Danjoe4 wrote: | I mean, I sympathize with the "burn it all down" attitude | because the (US) government needs to be culled. Education | costs exploded in the last 50 years because the government | got involved. Fiscal irresponsibility is the new normal | because the government will get involved to bail out the | banks; why not give out credit like candy? Housing costs | are insane because governments get involved via zoning to | artificially reduce supply. US military spending today is | (inflation adjusted) _almost as high as during WW2_. | Federal government spending is 37% of our annual GDP which | is almost certainly slowing our economic growth. | | Someone needs to take an axe to the US fed. If we reduce | federal spending by 75%, do you honestly think that would | be a bad thing? | | The US has produced all the innovation and prosperity and | our government was founded on the principle of "fuck the | government". Government overgrowth is the problem. | jona-f wrote: | You're coming off rather paternalistic to me. At least in my | circles calling countries "developed" and "less developed" is | frowned upon. Might even be called racist. People would now | probably rather call it "privileged" and "less privileged", but | in my opinion it's the same paternalistic thing. | | Why not let others sort out there own problems while you take | care of your own. Then work together on global problems like | this one on equal terms. | | Also, instead of helping, stopping the exploitation would | suffice. All this charity and "helping" is a public charade so | people like you can keep ignorant about what's really going on. | DoreenMichele wrote: | If you must insult me, the word you are looking for here is | _maternalistic._ | | Please and thank you. | jona-f wrote: | I did not mean to insult you, i actually tried to make an | argument. Nor was I looking for maternalistic. That's a | different thing and i meant the negatively connoted one. | Also reading again I realize I went too far saying _all_ | the helping, which is an unfortunate generalization, | surely, being compassionate is a good thing. | DoreenMichele wrote: | I'm a woman. It's pretty well established that lack of | rights and education for women is a root cause of high | birth rates and other negative factors being discussed | here. | | "Paternalistic" implicitly assumes I'm male and that's | kind of a problem if we are wanting to treat all people | with respect as a baseline means to make the world a | better place. | | We absolutely shouldn't be interfering in a _colonial_ | sort of fashion, but the reality is that "not | interfering _at all_ " is not a realistic goal. The only | way you get that is by not interacting at all and that | amounts to calling for not trading with poorer countries | which is an excellent means to ensure they remain poor | and can't develop. | | The reality is we already do interfere and often in ways | that make the people going in to "help" feel good more | than _really helping._ Real help does, in fact (as you | suggested), require one to have some kind of baseline | respect for people that many people lack generally. | | I will suggest that if you think _maternalistic_ has | positive connotations but _paternalistic_ has negative, | you should spend some time examining your implicit | assumptions about men, women, parenting roles, etc and | wonder exactly why you think the female-coded version of | that word is not negative but the male-coded version is. | | FWIW: I'm an environmental studies major (as background | for wanting to do urban planning) and I'm far from | _ignorant_. If you weren 't intending to insult me, | leading with calling me paternalistic and ending with | saying "...so people like you can keep ignorant..." | seriously fails to achieve the stated intentions. | codezero wrote: | I'm pretty sure they were using the term to refer to the | concept of paternalism: | https://en.m.wikipedia.org/wiki/Paternalism | | not as a gendered term targeted at you. | constantly wrote: | Just a heads up: paternalism or being paternalistic is a | concept unrelated to the user's gender. It means | advocating for action that limits a groups freedom or | autonomy. Maternalism has a different meaning. You being | one gender or another has no bearing on whether it was | the correct word for the argument. It wasn't quite the | right word, condescending would probably have been better | given the context of their phrases. | DoreenMichele wrote: | Thank you. I stand by my opinion that gender issues are a | factor in global poverty, so someone insisting the cure | for such is to respect people and not think you know | what's best for them should find gender-neutral terms to | make that point in line with their stated values or at | least check the gender of the individual they are | attacking and insulting (in violation of HN guidelines) | and use gender appropriate insults if they insist on | getting personal. | constantly wrote: | Totally agree with your statement that gender issues are | a factor in global economics, and that we should strive | to use gender-neutral phrasing whenever practical. | Danjoe4 wrote: | The euphemisms are insufferable | DoreenMichele wrote: | I'm actually not someone big on insisting we say | "humankind" instead of "mankind" or similar. I did check | the link talking about _paternalism_ and I can understand | where the practice of using the word that way comes from, | but it implicitly smears _fatherly_ behavior and | implicitly reinforces an assumption that men have | political and economic power and women don 't. | | Gendered language is kind of a thorny issue for the | English language. Not all languages are like English. | Japanese and Farsi default to gender-neutral pronouns and | cultures that default to calling people by their family | name instead of their given name also sidestep a lot of | these issues. | | The US had a women-only baseball league during World War | II and someone said (or somewhere I read) that it was the | era of _radio_ broadcasts and baseball defaults to | referring to players by their last names, so listening to | a game of baseball with women-only was experientially | nearly identical to listening to men 's baseball: | | "And Smith is up to bat and knocks it out of the park for | a home run, winning the game!" | | It's probably a fiercely fought battle with English | because it's the default lingua franca for the world and | doesn't play well with a lot of cultures that feel forced | to use it. Various proposals for fixing it come from | interest groups rather than arising naturally in an | _emergent_ fashion and strike people as unnatural, top- | down solutions to a problem they personally may not have, | so see no reason to pursue. | | /off-topic tangent, oops, because linguistics and social | issues are both interests of mine | theduder99 wrote: | stop misgendering me!!! | DoreenMichele wrote: | Nah, my personal policy is to ignore that in most cases. | If you aren't insulting me while lecturing me that _the | cure for what ails this world is genuine respect for | others_ , I generally interpret that as "DoreenMichele | fits in with this overwhelmingly male forum and her | behavior doesn't just scream _I 'm a woman._" | | You would know that if you read my blogs. I wrote a long | and detailed blog post about that once. | ClassyJacket wrote: | "Why not let others sort out there own problems while you | take care of your own." | | Literally the entire point of the comment you were replying | to was to explain why you help others sort out their | problems. | hpenvy wrote: | TIL it's paternalistic to give people in 3rd world countries | free things that they like. | iwontberude wrote: | I had this realization when I was like 8 years old. It goes to | show how undemocratic our governments are that we still cannot | get the leaders, who are more insulated from the effects, to | act on our vulnerability. | robertlagrant wrote: | > We currently are de facto breeding antibiotic resistant | infections | | For my understanding, if no one else's: are there a lot of | places without decent water, but with antibiotics? What's | causing that strange inconsistency? | dralley wrote: | Yes, absolutely. Proper water infrastructure is both | difficult and expensive to develop, and requires constant | maintenance. | | Antibiotic pills are cheap and easy to distribute. | akdor1154 wrote: | Anecdotal, but most towns in Vietnam you'd want to boil your | water, and if you want antibiotics you go to the pharmacy, | pay about $2, and get some. | | What's causing it? The free market is working great to build | the systems to get drugs to people. In fact if a pharmacist | refused to give out antibiotics when they weren't needed, the | pharmacist would probably just go out of business because the | customer would just head up the street to the next guy. | | The free market is not so hot at building expensive | infrastructure like safe water in a tropical biome, that | requires government involvement (not meaning to rag on SE | Asian governments: building this stuff is difficult even if | your country has been stable for the last 100 years, which is | a luxury they haven't been lucky enough to have) | DoreenMichele wrote: | _In a global assessment for 103 countries, after accounting | for type of governance, education, economy, health care | spending and community infrastructure, it was concluded that | reducing antibiotic consumption alone would not control | resistance. Independent of antibiotic consumption, poor | infrastructure (e.g. sanitation), poor governance (e.g. | corruption) and low health expenditure were all associated | with higher rates of resistance._ | | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782542/ | piker wrote: | My dad is a severe paralytic polio survivor and turns 70 next | year. He's a happy man, but his life has been hard in | incomprehensible ways. As a father now, I cannot imagine what his | parents went through when he was paralysed in the hospital at the | age of 2. The world will be a better place without the fear of | polio. Let us hope. | DoreenMichele wrote: | I wish we would also figure out how to fix people damaged in | this fashion rather than accepting that you will just be maimed | for life. | kbenson wrote: | What are you referring to peiple accepting? That polio has no | cure, or that we we don't know how to cure paralysis due to | nerve and motor neuron destruction? | | The former I think people accept because if we can eradicate | it through vaccination then it's a problem solved, so we are | working towards that. The latter I don't think anyone | actually accepts, it's just a hard problem and progress is | slow. | DoreenMichele wrote: | You tend to hear mostly about research into repairing | nerves damaged due to injury. It seems to me that a broken | neck would be a harder thing to fix than neurons impaired | by infection. | | It seems likely to me that if you can identify the | nutrients depleted by the infection and also actually clear | the infection from the body, this should be relatively easy | to repair compared to something like a broken neck. | | I did a quick search ("are there any organizations working | specifically on polio paralysis" on Bing) and most hits are | about the news currently under discussion, not about | research into treating the paralysis. I did find this page | on The Christopher and Dana Reeve Foundation site: | | https://www.christopherreeve.org/todays-care/living-with- | par... | | They indicate there are a lot of studies on Post Polio | Syndrome, which is not per se research into treating | paralysis. Some stats from the page: | | _Over 12 million people, worldwide have been affected by | polio as indicated by the CDC. | | There is no central system for reporting post-polio | syndrome, but it is estimated that 300,000 individuals are | survivors of polio in the United States and have mild to | severe symptoms. | | Of the 300,000 survivors of polio, it is estimated that of | one fourth to one half may develop some form of post-polio | symptoms._ | dralley wrote: | > It seems to me that a broken neck would be a harder | thing to fix than neurons impaired by infection. | | Does it? We're still unable to cure MS, just slow or | stall the progression of it. | DoreenMichele wrote: | Yes, _it seems to me_ that way. | | AKA _personal opinion_. | ryzvonusef wrote: | I'm from Pakistan, and polio eradication has been frustrating to | say the least. | | Polio teams workers still get killed regularly, and in fact, in | searching for news on polio workers, discovered tragically that | one worker was killed just today: | | https://twitter.com/TNNEnglish/status/1727695070906957889 | | and polio vaccination drives have been delayed in other areas too | (separate from the unfortunate incident above) | | https://twitter.com/MajidBuhair/status/1727755867666452722 | | I mean what can I say of others, back in my own extended family, | I have cousins who refused to vaccinate their kids at all, like | no vaccine of any kind, and nothing I or anyone can say will | change their mind. Thing is that they are _not_ illiterate, they | have been to schools, they are just.. stubborn. | | That means attack vectors exist in all directions. | | I personally discovered this the hard way when I randomly caught | a case of mumps despite having been vaccinated as a child with | the MMR vaccine (my dumbass doctor thought I had "mild- | tonsillitis" and sent me home with antibiotics) Not sure where I | caught it from but thankfully it was mild and I recovered after | 10 days of absolute misery. | | But the moral of the story is, not only is polio unlikely to be | eradicated, but even people like me who thought they were covered | by vaccination from dutiful parents, are still vulnerable to all | these diseases, either as patients or carriers. | | Our vaccination drives are not forming effective vaccine shields, | and that means we have to think of treatment and not prevention | as the "first" step of our fights against diseases. | | ____ > The result came back a month later: it | was wild polio type 1, not seen in the continent since 2016. | > Sequencing traced its origin to Pakistan, but also revealed | that the virus had been circulating for two years undetected -- | possibly in Malawi, and possibly elsewhere. Because Malawi had no | wastewater surveillance at the time, it was impossible to know. | | If we can re-introduce polio to a place where polio had been | eradicated, then I fear one day the world will get frustrated | just decide to quarantine us, and I wouldn't know who to blame. | selimthegrim wrote: | What I saw on Pakistani TV/newspapers was people complaining | that government just wanted them to get tika (vaccination) but | wouldn't listen to them about anything else or fix any of their | other problems (roads, schools, jobs) | serial_dev wrote: | > even people like me who thought they were covered by | vaccination from dutiful parents, are still vulnerable to all | these diseases | | I was surprised to see that some of the vaccines I thought are | rock solid share some traits with the great COVID vaccines: not | everyone develops immunity, and the immunity gets worse and | worse over time, so you need "boosters" every 5-10 years, and | most adults have very little actual protection against the | diseases they thought they are vaxxed against. | | Example, whooping cough: | | > In children, DTaP protects: > (...) About 7 out of 10 | children for five years after the fifth shot. > In adults, Tdap | protects: > About 7 in 10 people for the first year after the | shot. > About 4 in 10 people for four years after the shot. | | https://my.clevelandclinic.org/health/drugs/21639-pertussis-... | | These numbers don't look all that great to me. | nojonestownpls wrote: | For some added context on the vaccine distrust: | | > In the early 2010s, the CIA ran a fake vaccination program in | Abbottabad, offering free Hepatitis B vaccines to children in | an attempt to collect DNA evidence linking Osama bin Laden to | the compound where he was suspected of residing. It is unclear | how samples were to be collected or how they would lead to bin | Laden, but when news of this scheme broke, it added proof to | existing conspiracy theories about vaccinations. As a | consequence, many local leaders began urging people not to | vaccinate their kids, various districts banned vaccination | teams, and the Taliban issued a fatwa against vaccination | programs. To this day, local leaders rail against vaccines as | Western spying programs. | | - https://www.vox.com/first-person/22256595/vaccine-covid- | paki... | niemandhier wrote: | Polio would likely be eradicated already, if not for a CIA op | that used a vaccination program as a cover to get DNA from bin | Laden. | | Source: | https://www.thelancet.com/journals/lancet/article/PIIS0140-6... | | As a result part of the Afghan and Pakistani population stopped | believing in what WHO workers told them. | actuallyalys wrote: | The CIA operation was definitely a setback for polio | eradication and doubtless caused other harms to public health, | but the article this thread is about discusses numerous | challenges to eradication so I suspect even without the CIA | campaign, we'd still be a ways away from eradication. | Animats wrote: | Polio is coming back, a little.[1] | | There are two polio vaccines. One takes four injections, spaced | months apart, and cannot cause polio because it doesn't contain | an active virus. The other is a live-virus vaccine, as a pill, | and has about a one in a million chance of causing polio. These | are both 1950s technology. | | "For most people, (polio) has no symptoms. For about a quarter of | people who get the polio virus, they will have mild symptoms that | may include fever, gastroenteritis, upset stomach, aches, and so- | on--in other words, flu-like symptoms. Most people would not know | they have a polio infection because those symptoms are so common | to many other infections." | | "Somewhere around one in 200 to one in 1000 people that get | infected with the polio virus will develop poliomyelitis, which | is also known as paralytic polio or acute flaccid paralysis but | can also include presentations that are less and more severe, | including delayed post-polio syndrome with mild disability or | acute respiratory failure and death." | | Those who are not suffering still spread the disease. | | What happened when the anti-vaxxers reached Pakistan.[2] | | [1] https://medicine.yale.edu/news-article/is-polio-making-a- | com... | | [2] https://archive.is/wJhkF | JumpCrisscross wrote: | > _Polio is coming back, a little_ | | This was a valid question in 2022. I don't think it's the case | anymore in 2023. We seem to have eliminated it from the African | continent. At this point, it's contained to Pakistan and | Afghanistan. One of those is cooperating with vaccination | efforts; the other is effectively quarantining itself. | serial_dev wrote: | You mean the CIA reached Pakistan. | | > The CIA's efforts to capture Osama bin Laden via a fake | vaccination drive in Pakistan led to a rise in vaccine | hesitancy in the years after the scheme was revealed. | | https://www.newscientist.com/article/2277145-cias-hunt-for-o... | SpaceManNabs wrote: | That is great news. I sincerely hope we continue that trajectory. | I am afraid at the uptick of recent antivaxxers but hopefully | that is just temporary. | | I went to the ER recently and saw an orthodox jewish kid in a | polio bed. I felt so sad for him. (This was in NYC). | MrDresden wrote: | After seeing news about a rise in polio cases last year I | immediately looked at my vaccinations. | | Turned out I was a few years overdue for a 10 year booster (which | was immediately remedied). | scottLobster wrote: | Don't worry, Rockland County NY will ensure it remains "on the | Brink" indefinitely. | londons_explore wrote: | Unfortunately, I believe the vaccine-type cases won't be | eliminated for decades or maybe centuries... | | Stopping vaccinating populations with oral polio vaccine tends to | make cases trend upwards, and the only fix for that I suspect is | to change over to injectable vaccines for a whole generation of | people (ie. 50 years). | raincom wrote: | First polio cases linked to new oral vaccine detected in Africa: | https://www.science.org/content/article/first-polio-cases-li... ___________________________________________________________________ (page generated 2023-11-23 23:00 UTC)