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Precision Public Health in Action: New CDC Pilot Projects Integrate Human Genomics into Public Health Surveillance and Applied Research

['Mindy Clyne', 'W. David Dotson', 'Muin J. Khoury', 'Office Of Genomics', 'Precision Public Health', 'Centers For Disease Control', 'Prevention', 'Atlanta']

Date: 2022-02-14 00:00:00

In collaboration with the CDC Office of Advanced Molecular Detection, we recently launched a new, five-year initiative to strengthen public health capacity by introducing elements of human genomics into both public health surveillance and applied research. We report here on the successful launch of one of the initiative’s components.

The Office of Genomics and Precision Public Health (OGPPH) put out a call for pilot exemplar projects throughout CDC and ATSDR Centers, Institutes, and Offices (CIOs). The process yielded 23 applications from across CDC, covering infectious and noninfectious disease topics throughout the lifespan.

Applications were reviewed by OGPPH staff and an objective review panel. The reviewers ranked the proposals according to six criteria: scientific merit, alignment with public health genomics priority areas, potential public health impact, focus on health equity, potential for growing program capacity, and feasibility.

Six projects across five CIOs were selected for funding in 2022 and 2023. They cover a wide range of topics, including:

A summary of these projects can be found in Table 1 below. In the coming weeks, investigators from each project will describe their study and its potential impact.

We are excited to announce these six projects and will regularly report progress in these and other efforts to integrate human genomics in public health surveillance and applied research.

This is just the beginning. We will continue working with the public health community at CDC to strengthen and sponsor other proposals. Our goal is for this process to lead to a new community of practice in genomics and precision public health.

We are interested in your feedback about priority areas for human genomics and public health. Please submit your input below.

Table 1: Six Pilot Projects in Human Genomics and Public Health Surveillance and Applied Research in 2022 and 2023.

[1] Url: https://blogs.cdc.gov/genomics/2022/02/14/precision-public-health-4/

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