A 70-year-old woman presented with dog bite avulsion to her upper lip. She lost about seventy percent of upper red lip and a part of white lip including the vermilion border. Through the wound, we could see the cut edges of the obricularis oris muscle in both sides. In the center of the wound, there was a part of mucosa left and she lost most of the obricularis oris muscle. She said that blood spouted from the wound directly after injury. We supposed that the both side of labial arteries were cut off in the muscle stumps. When she arrived the hospital, hemostasis had been achieved. We gave her the infusions of antibiotic Cefazolin only one day. Day 2, we confirmed that no signs of infection were seen. We did not use antibiotics during following days. We used Gentamicin ointment for topical use, and sealed the wound with the dressing which had brand name Tielle(tm) over the applied ointment. Day 4, the wound was covered with proper granulation. Days 7, we changed the dressing materials to Allevyn(tm) and ointment. Day 11, the defect of mucosa and skin reduced rapidly. Her lip was regenerated to form normally. We changed dressing materials to Duoactive ET(TM) only. Day 21, the wound closed completely and her lip formed normally. With regenerated lip, she could close her mouth, eat without problems and speak fully functionally.