Considering male and female is a spectrum and biochemically, we have the same stuff inside, just of different levels at different times of the day. If I drink coffee or cocoa, I get more copper which increases estrogen making me slightly more female. If I eat pumpkin seeds which have zinc, I become slightly more male because zinc leads to testosterone. Outside of the child-bearing capacity which comes from having formed those particularly shaped organs, ovum? or testicular sacs? Does your thingie go in or does it go out? ... not a heck of a lot of difference. Socially? Usually a big difference. Training begins at babies. Gets worst around 8 yrs old and it's downhill from there.