An everyday example of a constraint is: a definition. The definition can be fixed. Even the very word itself: define. Directly from Latin here: definire "to limit, determine, explain," from de- "completely" (see de-) + finire "to bound, limit," from finis "boundary, end" boundaries, constraints. A set of markers that tell someone, "This is defined as depression", are constraints on the system and the actions/behaviors/thoughts/whatever is measurable that is occuring acively *within* the boundaries of that definition, is considered "depression". The definition fixes the measurement; but the measurement does not fix the active mind from thinking/emoting - and potentially being more than its definition. Rather self-fulfilling in a way.