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       # 2022-01-03 - Type 2 Diabetes and Fasting by Jason Fung
       
       An excerpt from the introduction to The Complete Guide to Fasting by
       Jason Fung (2016).
       
       However, in my work with type 2 diabetics, I realized that there was
       an inconsistency between the treatment of obesity and the treatment
       of type 2 diabetes, two problems that are closely linked.  Reducing
       insulin may be effective in reducing obesity, but doctors like me
       were prescribing insulin as a cure-all treatment for diabetes, both
       types 1 and 2.  Insulin certainly lowers blood sugars.  But just as
       surely, it causes weight gain.  I finally realized that the answer
       was really quite simple.  We were treating the wrong thing.
       
       Type 1 diabetes is an entirely different problem than type 2.  In
       type 2 diabetes, the body's own immune system destroys the
       insulin-producing cells in the pancreas.  The resulting low insulin
       level leads to high blood sugar.  Therefore, since insulin levels are
       low to begin with, it makes sense to treat the problem with
       supplemental insulin.  And sure enough, it works.
       
       In type 2 diabetes, however, insulin levels are not low but high.
       Blood sugar is elevated not because the body can't make insulin but
       because it's become resistant to insulin--it doesn't let insulin do
       its job.  By prescribing more insulin to treat type 2 diabetes, we
       were not treating the underlying cause of high blood sugar: insulin
       resistance.  That's why, over time, patients saw their type 2
       diabetes get worse and required higher and higher doses of
       medications.
       
       But what caused the high insulin resistance in the first place?  This
       was the real question.  After all, we didn't stand a chance of
       treating the underlying disease if we didn't know what caused it.  As
       it turns out, insulin causes insulin resistance.  The body responds
       to excessively high levels of any substance by developing resistance
       to it.  If you drink excessive alcohol, your body will develop
       resistance to it, up to a point--we often call this "tolerance."  If
       you use prescription sleep medications such as benzodiazepines, your
       body will develop resistance.  The same is true for insulin.
       
       Excessive insulin causes obesity, and excessive insulin causes
       insulin resistance, which is the disease known as type 2 diabetes.
       
       With that understanding, the problem with how doctors treat type 2
       diabetes became clear: were were prescribing insulin to treat it,
       when excessive insulin was the problem in the first place.
       Instinctively, most patients knew what we were doing was wrong.  They
       would say to me, "Doctor, you have always told me that weight loss is
       critical in the treatment of type 2 diabetes, yet you have prescribed
       me insulin, which has made me gain so much weight.  How is that good
       for me?"  I never had a good answer for this.  Now I know why.  They
       were absolutely right; it wasn't good for them.  As patients took
       insulin, they gained weight, and when they did, their type 2 diabetes
       got worse, demanding more insulin.  And the cycle repeated: they took
       more insulin, they gained more weight, and as they gained more
       weight, they needed more insulin, it was a classic vicious cycle.
       
       We doctors had been treating type 2 diabetes exactly wrong.  With the
       proper treatment, it is a curable disease.  Type 2 diabetes like
       obesity, is a disease of too much insulin.  The treatment is to lower
       insulin, not to raise it.  We were making things worse.  We were
       fighting fire with gasoline.
       
       I needed to help my obesity and type 2 diabetes patients lower their
       insulin levels, but what was the best approach?  Certainly, there are
       no medications that do this.  There are surgical options that help,
       such as bariatric surgery (commonly called "stomach stapling"), but
       they are highly invasive and have many irreversible side effects.
       The only feasible treatment left was dietary: reducing insulin levels
       by changing eating habits.
       
       ...
       
       I gave my patients lengthy sessions of dietary advice.  I reviewed
       their food diaries.  I begged.  I pleaded.  I cajoled.  But the diets
       just didn't work.  The advice seemed hard to follow; my patients had
       busy lives and changing their dietary habits was difficult,
       especially since much of it ran contrary to the standard advice to
       eat low-fat and low-calorie.
       
       But I couldn't just give up on them.  Their health, and indeed their
       very lives, depended upon reducing their insulin levels.  If they had
       trouble avoiding certain foods, then why not make it as simple as
       possible?  They could simply eat nothing at all.  The solution was,
       in a word, fasting.
       
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       tags: book,fasting,health
       
       # Tags
       
 (DIR) book
 (DIR) fasting
 (DIR) health