[HN Gopher] Light-shrinking material lets ordinary microscope se...
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       Light-shrinking material lets ordinary microscope see in super
       resolution
        
       Author : thedday
       Score  : 82 points
       Date   : 2021-06-01 18:01 UTC (4 hours ago)
        
 (HTM) web link (phys.org)
 (TXT) w3m dump (phys.org)
        
       | jl2718 wrote:
       | > The technology consists of a microscope slide that's coated
       | with a type of light-shrinking material called a hyperbolic
       | metamaterial. It is made up of nanometers-thin alternating layers
       | of silver and silica glass.
        
       | phkahler wrote:
       | Is something like this useful for chip fabrication somehow?
        
         | syntaxing wrote:
         | I was wondering the same exact thing. Wouldnt this be very
         | helpful for EUV masks?
        
         | Narew wrote:
         | probably not, speckle is random and they use several images to
         | reconstruct the final result.
        
           | buescher wrote:
           | You'd have to start from the speckles to illuminate it in
           | reverse somehow!
        
           | swiley wrote:
           | I thought they already used holography to make masks with
           | certain repeating patterns.
        
       | _Microft wrote:
       | The paper is open access and linked from the bottom of the
       | article btw.
       | 
       | [PDF] https://www.nature.com/articles/s41467-021-21835-8.pdf
        
       | m4x wrote:
       | > The wide-field of view image reconstruction takes 10 mins on a
       | desktop computer with a GTX 1080Ti graphics card and a i7-8700k
       | CPU to reconstruct an image with 100 by 100 raw pixels
       | 
       | That's an impressive amount of computation per pixel
        
         | nojokes wrote:
         | It is but this is also fairly ancient system. More modern
         | systems should be able to shrink time needed for computation -
         | also research facilities may have access to a cluster.
        
           | robotresearcher wrote:
           | I looked it up. GTX1080Ti is 4 years old.
        
             | LeifCarrotson wrote:
             | Same 4-year age for the i7-8700k. It's true that it's about
             | half as fast as a modern Ryzen 7 5800X or brand-new Intel
             | i7-11700K, and if you could get a new Nvidia 3080 or AMD RX
             | 6900-XT they'd have a similar doubling in speed, but it's
             | not ancient.
             | 
             | Regardless, does the difference between 5 minutes or 10
             | minutes for 10,000 pixels really matter? It still means
             | that you're running on the order of a hundred thousand
             | operations per pixel; what can you possibly need to do that
             | requires that much processing?
        
       | throwaway2568 wrote:
       | This article is not that clear (there is no frequency shift
       | occuring). As others say, the authors are using speckle imagery,
       | which relies on the wavevector of the illuminating beam (rather
       | than the frequency). By adding the hyperbolic metamaterial the
       | authors can access wavevectors beyond the diffraction limit, so
       | that once they do the appropriate prost processing achieve super
       | resolution imagery.
       | 
       | It's not directly related but reciprocal space and Fourier
       | imaging is quite interesting for those that are not aware of it
       | (such as estimating the size of a crystal lattice by looking at
       | the diffraction pattern)
        
         | dekhn wrote:
         | Most computer folks are actually unaware that physicists were
         | doing fourier transforms using optics long before the FFT
         | existed. You can do physical convolutions using lenses.
        
         | N1H1L wrote:
         | Yes - the technique is called ptychography [0] and there have
         | been several recent electron microscopy papers too
         | demonstrating how this technique (image reconstruction from
         | Fourier space patterns) can reach beyond instrumental
         | resolution limits [1, 2].
         | 
         |  _References_ :
         | 
         | [0] https://en.wikipedia.org/wiki/Ptychography
         | 
         | [1] 2018 Nature Paper:
         | https://www.nature.com/articles/s41586-018-0298-5 arXiv
         | version: https://arxiv.org/abs/1801.04630
         | 
         | [2] 2021 Science Paper:
         | https://science.sciencemag.org/content/372/6544/826 arXiv
         | version: https://arxiv.org/abs/2101.00465
        
       | mountainboy wrote:
       | Cool, and only about 90 years after Royal Raymond Rife.
        
       | whatshisface wrote:
       | The title "light-shrinking material" makes it sound like they are
       | adding a layer of something that turns optical wavelengths into
       | UV, but there's a mention of scattering and reconstruction that
       | makes it sound like more might be involved.
        
         | _Microft wrote:
         | I think you are thinking of oil immersion (microscopy) there.
         | They are using a meta material as a superlens though which
         | allows to work around the diffraction limit.
         | 
         | Edit: they seem to be improving an already known technique
         | called "structured illumination microscopy". For that, the
         | sample is illuminated with a light pattern (here: a speckle
         | pattern) and the phase of the light is shifted in the process.
         | After collecting various images, an image of better resolution
         | can be computed. Their improvement seems to be to use a
         | particular meta material that allows to capture far more
         | spatial detail than otherwise.
         | 
         | Links: https://en.wikipedia.org/wiki/Oil_immersion ,
         | https://en.wikipedia.org/wiki/Superlens ,
         | https://en.wikipedia.org/wiki/Plasmonic_metamaterial#Hyperbo...
         | , https://en.wikipedia.org/wiki/Diffraction-limited_system ,
         | https://en.wikipedia.org/wiki/Super-resolution_microscopy#St...
        
         | Narew wrote:
         | > As light passes through, its wavelengths shorten and scatter
         | to generate a series of random high-resolution speckled
         | patterns.
         | 
         | Speckle allow random illumination with small resolution. They
         | reconstruct several images with differente speckle pattern to
         | obtain better resolution on the object
        
       | [deleted]
        
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